Immunogenicity and efficacy of single antigen Gp63, polytope and polytopeHSP70 DNA vaccines against visceral leishmaniasis in experimental mouse model

PLoS ONE

Volumn 4, Issue 12, 2009, Pages

  Sachdeva, Rakhee ^a   Banerjea, Akhil C ^b   Malla, Nancy ^a   Dubey, Mohan Lal ^a  

^a POSTGRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH   (India)

^b NATIONAL INSTITUTE OF IMMUNOLOGY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

DNA VACCINE; EPITOPE; GAMMA INTERFERON; HEAT SHOCK PROTEIN 70; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 4; PLASMID DNA; PLASMID VECTOR; POLYTOPE DNA VACCINE; POLYTOPE HEAT SHOCK PROTEIN 70 DNA VACCINE; SINGLE ANTIGEN GLYCOPROTEIN 63 DNA VACCINE; UNCLASSIFIED DRUG; CYTOKINE; GLYCOPROTEIN GP63, LEISHMANIA; METALLOPROTEINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BAGG ALBINO MOUSE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFICACY; FEMALE; GENETIC IMMUNIZATION; IMMUNOGENICITY; LEISHMANIA DONOVANI; LIVER; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; SPLEEN; TH1 CELL; VISCERAL LEISHMANIASIS; ANIMAL; BIOSYNTHESIS; CELL DEATH; CELL PROLIFERATION; CELL SEPARATION; CHEMICALLY INDUCED DISORDER; DISEASE MODEL; GENETICS; IMMUNOASSAY; IMMUNOLOGY; PARASITOLOGY; PATHOLOGY; PLASMID; TREATMENT OUTCOME; VACCINATION;

LEISHMANIA DONOVANI; MUS;

ANIMALS; CELL DEATH; CELL PROLIFERATION; CELL SEPARATION; CYTOKINES; DISEASE MODELS, ANIMAL; EPITOPES; FEMALE; HSP70 HEAT-SHOCK PROTEINS; IMMUNOASSAY; LEISHMANIASIS, VISCERAL; LIVER; METALLOENDOPEPTIDASES; MICE; MICE, INBRED BALB C; PLASMIDS; SPLEEN; TREATMENT OUTCOME; VACCINATION; VACCINES, DNA;

EID: 77949517376     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0007880     Document Type: Article

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