Designing and engineering of DNA-vaccine construction encoding multiple CTL-epitopes of major HIV-1 antigens

Vaccine

Volumn 22, Issue 13-14, 2004, Pages 1672-1682

  Bazhan, Sergei I ^a   Belavin, Pavel A ^a   Seregin, Sergei V ^a   Danilyuk, Nadezhda K ^a   Babkina, Irina N ^a   Karpenko, Larisa I ^a   Nekrasova, Nadezhda A ^a   Lebedev, Leonid R ^a   Ignatyev, George M ^a   Agafonov, Alexander P ^a   Poryvaeva, Vera A ^b   Aborneva, Irina V ^b   Ilyichev, Alexander A ^a  

^a STATE RESEARCH CENTER OF VIROLOGY AND BIOTECHNOLOGY VECTOR   (Russian Federation)

^b Novosibirsk Region   (Russian Federation)

Author keywords

Cytotoxic T lymphocytes (CTL); Designing a poly CTL epitope based immunogen; DNA vaccine; HIV CTL epitopes; Human immunodeficiency virus (HIV); Immunogenicity; Polymerase chain reaction (PCR); Synthetic gene expression; T helper lymphocytes (Th)

Indexed keywords

DNA VACCINE; EPITOPE; HLA ANTIGEN CLASS 1; HUMAN IMMUNODEFICIENCY VIRUS ANTIGEN; PLASMID VECTOR;

ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ANTIGEN DETECTION; ANTIGEN SPECIFICITY; ANTIGEN STRUCTURE; ARTICLE; BLAST TRANSFORMATION; CLONOGENIC ASSAY; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DRUG DESIGN; ENZYME LINKED IMMUNOSORBENT ASSAY; EUKARYOTE; GENE CONSTRUCT; GENETIC ENGINEERING; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOBLOTTING; IMMUNOGENICITY; MACACA; MAJOR HISTOCOMPATIBILITY COMPLEX; NONHUMAN; PRIORITY JOURNAL; PROKARYOTE; PROTEIN ASSEMBLY; VACCINE PRODUCTION;

AIDS VACCINES; ANIMALS; ANTIBODY SPECIFICITY; BASE SEQUENCE; CELL DIVISION; DNA, VIRAL; DRUG DESIGN; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITOPES; ESCHERICHIA COLI; GENETIC ENGINEERING; HIV ANTIBODIES; HIV ANTIGENS; HIV-1; HUMANS; IMMUNOCHEMISTRY; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; PLASMIDS; T-LYMPHOCYTES, CYTOTOXIC; VACCINES, DNA;

EID: 11144357556     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2003.09.048     Document Type: Article

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