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Volumn 17, Issue 3, 2010, Pages 380-388

Dual transgene expression by foamy virus vectors carrying an endogenous bidirectional promoter

Author keywords

Bidirectional promoter; FV; Gene transfer; Hematopoietic stem cells

Indexed keywords

ALPHA GALACTOSIDASE; CD34 ANTIGEN; ENHANCED GREEN FLUORESCENT PROTEIN; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN H2; NERVE GROWTH FACTOR RECEPTOR; SPUMA VIRUS VECTOR; UNCLASSIFIED DRUG; VIRUS VECTOR;

EID: 77949424086     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/gt.2009.147     Document Type: Article
Times cited : (10)

References (39)
  • 1
    • 0034990304 scopus 로고    scopus 로고
    • Protection and in vivo selection of hematopoietic stem cells using temozolomide O6-benzylguanine, and an alkyltransferase-expressing retroviral vector
    • Sawai N, Zhou S, Vanin EF, Houghton P, Brent TP, Sorrentino BP. Protection and in vivo selection of hematopoietic stem cells using temozolomide, O6-benzylguanine, and an alkyltransferase-expressing retroviral vector. Mol Ther 2001; 3: 78-87.
    • (2001) Mol Ther , vol.3 , pp. 78-87
    • Sawai, N.1    Zhou, S.2    Vanin, E.F.3    Houghton, P.4    Brent, T.P.5    Sorrentino, B.P.6
  • 2
    • 34249789022 scopus 로고    scopus 로고
    • In vivo selection and chemoprotection after drug resistance gene therapy in a nonmyeloablative allogeneic transplantation setting in dogs
    • Gerull S, Beard BC, Peterson LJ, Neff T, Kiem HP. In vivo selection and chemoprotection after drug resistance gene therapy in a nonmyeloablative allogeneic transplantation setting in dogs. Hum Gene Ther 2007; 18: 451-456.
    • (2007) Hum Gene Ther , vol.18 , pp. 451-456
    • Gerull, S.1    Beard, B.C.2    Peterson, L.J.3    Neff, T.4    Kiem, H.P.5
  • 3
    • 33646561281 scopus 로고    scopus 로고
    • Multicistronic lentiviral vectors containing the FMDV 2A cleavage factor demonstrate robust expression of encoded genes at limiting MOI
    • Chinnasamy D, Milsom MD, Shaffer J, Neuenfeldt J, Shaaban AF, Margison GP et al. Multicistronic lentiviral vectors containing the FMDV 2A cleavage factor demonstrate robust expression of encoded genes at limiting MOI. Virol J 2006; 3: 14.
    • (2006) Virol J , vol.3 , pp. 14
    • Chinnasamy, D.1    Milsom, M.D.2    Shaffer, J.3    Neuenfeldt, J.4    Shaaban, A.F.5    Margison, G.P.6
  • 4
    • 38949190971 scopus 로고    scopus 로고
    • In vivo selection of hematopoietic stem cells transduced at a low multiplicity-of-infection with a foamy viral MGMT(P140K) vector
    • Cai S, Ernstberger A, Wang H, Bailey BJ, Hartwell JR, Sinn AL et al. In vivo selection of hematopoietic stem cells transduced at a low multiplicity-of-infection with a foamy viral MGMT(P140K) vector. Exp Hematol 2008; 36: 283-292.
    • (2008) Exp Hematol , vol.36 , pp. 283-292
    • Cai, S.1    Ernstberger, A.2    Wang, H.3    Bailey, B.J.4    Hartwell, J.R.5    Sinn, A.L.6
  • 5
    • 0037772187 scopus 로고    scopus 로고
    • Successful treatment of murine beta-thalassemia using in vivo selection of genetically modified, drug-resistant hematopoietic stem cells
    • Persons DA, Allay ER, Sawai N, Hargrove PW, Brent TP, Hanawa H et al. Successful treatment of murine beta-thalassemia using in vivo selection of genetically modified, drug-resistant hematopoietic stem cells. Blood 2003; 102: 506-513.
    • (2003) Blood , vol.102 , pp. 506-513
    • Persons, D.A.1    Allay, E.R.2    Sawai, N.3    Hargrove, P.W.4    Brent, T.P.5    Hanawa, H.6
  • 6
    • 0034170820 scopus 로고    scopus 로고
    • IRES-dependent second gene expression is significantly lower than cap-dependent first gene expression in a bicistronic vector
    • Mizuguchi H, Xu Z, Ishii-Watabe A, Uchida E, Hayakawa T. IRES-dependent second gene expression is significantly lower than cap-dependent first gene expression in a bicistronic vector. Mol Ther 2000; 1: 376-382.
    • (2000) Mol Ther , vol.1 , pp. 376-382
    • Mizuguchi, H.1    Xu, Z.2    Ishii-Watabe, A.3    Uchida, E.4    Hayakawa, T.5
  • 7
    • 0035880772 scopus 로고    scopus 로고
    • Composition and arrangement of genes define the strength of IRES-driven translation in bicistronic mRNAs
    • Hennecke M, Kwissa M, Metzger K, Oumard A, Kroger A, Schirmbeck R et al. Composition and arrangement of genes define the strength of IRES-driven translation in bicistronic mRNAs. Nucleic Acids Res 2001; 29: 3327-3334.
    • (2001) Nucleic Acids Res , vol.29 , pp. 3327-3334
    • Hennecke, M.1    Kwissa, M.2    Metzger, K.3    Oumard, A.4    Kroger, A.5    Schirmbeck, R.6
  • 8
    • 0242285647 scopus 로고    scopus 로고
    • Alternative ways to think about mRNA sequences and proteins that appear to promote internal initiation of translation
    • Kozak M. Alternative ways to think about mRNA sequences and proteins that appear to promote internal initiation of translation. Gene 2003; 318: 1-23.
    • (2003) Gene , vol.318 , pp. 1-23
    • Kozak, M.1
  • 9
    • 0021726790 scopus 로고
    • Genes with promoters in retrovirus vectors can be independently suppressed by an epigenetic mechanism
    • Emerman M, Temin HM. Genes with promoters in retrovirus vectors can be independently suppressed by an epigenetic mechanism. Cell 1984; 39: 449-467.
    • (1984) Cell , vol.39 , pp. 449-467
    • Emerman, M.1    Temin, H.M.2
  • 10
    • 0036135719 scopus 로고    scopus 로고
    • Transcrip-tional interference by independently regulated genes occurs in any relative arrangement of the genes and is influenced by chromosomal integration position
    • Eszterhas SK, Bouhassira EE, Martin DI, Fiering S. Transcrip-tional interference by independently regulated genes occurs in any relative arrangement of the genes and is influenced by chromosomal integration position. Mol Cell Biol 2002; 22: 469-479.
    • (2002) Mol Cell Biol , vol.22 , pp. 469-479
    • Eszterhas, S.K.1    Bouhassira, E.E.2    Martin, D.I.3    Fiering, S.4
  • 11
    • 10744229841 scopus 로고    scopus 로고
    • Lentiviral vectors with two independent internal promoters transfer high-level expression of multiple transgenes to human hematopoietic stem-progenitor cells
    • Yu X, Zhan X, D'Costa J, Tanavde VM, Ye Z, Peng T et al. Lentiviral vectors with two independent internal promoters transfer high-level expression of multiple transgenes to human hematopoietic stem-progenitor cells. Mol Ther 2003; 7: 827-838.
    • (2003) Mol Ther , vol.7 , pp. 827-838
    • Yu, X.1    Zhan, X.2    D'Costa, J.3    Tanavde, V.M.4    Ye, Z.5    Peng, T.6
  • 12
    • 39449083194 scopus 로고    scopus 로고
    • Bidirectional promoter interference between two widely used internal heterologous promoters in a late-generation lentiviral construct
    • Curtin JA, Dane AP, Swanson A, Alexander IE, Ginn SL. Bidirectional promoter interference between two widely used internal heterologous promoters in a late-generation lentiviral construct. Gene Therapy 2008; 15: 384-390.
    • (2008) Gene Therapy , vol.15 , pp. 384-390
    • Curtin, J.A.1    Dane, A.P.2    Swanson, A.3    Alexander, I.E.4    Ginn, S.L.5
  • 13
    • 0028058011 scopus 로고
    • Foot-and-mouth disease virus 2A oligopep-tide mediated cleavage of an artificial polyprotein
    • Ryan MD, Drew J. Foot-and-mouth disease virus 2A oligopep-tide mediated cleavage of an artificial polyprotein. EMBO J 1994; 13: 928-933.
    • (1994) EMBO J , vol.13 , pp. 928-933
    • Ryan, M.D.1    Drew, J.2
  • 14
    • 0034973713 scopus 로고    scopus 로고
    • Recombinant AAV vectors containing the foot and mouth disease virus 2A sequence confer efficient bicistronic gene expression in cultured cells and rat substantia nigra neurons
    • Furler S, Paterna JC, Weibel M, Bueler H. Recombinant AAV vectors containing the foot and mouth disease virus 2A sequence confer efficient bicistronic gene expression in cultured cells and rat substantia nigra neurons. Gene Therapy 2001; 8: 864-873.
    • (2001) Gene Therapy , vol.8 , pp. 864-873
    • Furler, S.1    Paterna, J.C.2    Weibel, M.3    Bueler, H.4
  • 15
    • 16344365811 scopus 로고    scopus 로고
    • Skipping the co-expression problem: The new 2A 'CHYSEL' technology
    • de Felipe P. Skipping the co-expression problem: the new 2A 'CHYSEL' technology. Genet Vaccines Ther 2004; 2: 13.
    • (2004) Genet Vaccines Ther , vol.2 , pp. 13
    • De Felipe, P.1
  • 17
    • 15244351083 scopus 로고    scopus 로고
    • Coordinate dual-gene transgenesis by lentiviral vectors carrying synthetic bidirectional promoters
    • Amendola M, Venneri MA, Biffi A, Vigna E, Naldini L. Coordinate dual-gene transgenesis by lentiviral vectors carrying synthetic bidirectional promoters. Nat Biotechnol 2005; 23: 108-116.
    • (2005) Nat Biotechnol , vol.23 , pp. 108-116
    • Amendola, M.1    Venneri, M.A.2    Biffi, A.3    Vigna, E.4    Naldini, L.5
  • 18
    • 34548843603 scopus 로고    scopus 로고
    • Lentiviral vectors containing an enhancer-less ubiquitously acting chromatin opening element (UCOE) provide highly reproducible and stable transgene expression in hemato-poietic cells
    • Zhang F, Thornhill SI, Howe SJ, Ulaganathan M, Schambach A, Sinclair J et al. Lentiviral vectors containing an enhancer-less ubiquitously acting chromatin opening element (UCOE) provide highly reproducible and stable transgene expression in hemato-poietic cells. Blood 2007; 110: 1448-1457.
    • (2007) Blood , vol.110 , pp. 1448-1457
    • Zhang, F.1    Thornhill, S.I.2    Howe, S.J.3    Ulaganathan, M.4    Schambach, A.5    Sinclair, J.6
  • 19
    • 0037188910 scopus 로고    scopus 로고
    • Bidirectional gene organization: A common architectural feature of the human genome
    • Adachi N, Lieber MR. Bidirectional gene organization: a common architectural feature of the human genome. Cell 2002; 109: 807-809.
    • (2002) Cell , vol.109 , pp. 807-809
    • Adachi, N.1    Lieber, M.R.2
  • 20
    • 1542719907 scopus 로고    scopus 로고
    • Origins of bidirectional promoters: Computational analyses of intergenic distance in the human genome
    • Takai D, Jones PA. Origins of bidirectional promoters: computational analyses of intergenic distance in the human genome. Mol Biol Evol 2004; 21: 463-467.
    • (2004) Mol Biol Evol , vol.21 , pp. 463-467
    • Takai, D.1    Jones, P.A.2
  • 22
    • 0030844927 scopus 로고    scopus 로고
    • Expression of the murine RanBP1 and Htf9-c genes is regulated from a shared bidirectional promoter during cell cycle progression
    • Guarguaglini G, Battistoni A, Pittoggi C, Di Matteo G, Di Fiore B, Lavia P. Expression of the murine RanBP1 and Htf9-c genes is regulated from a shared bidirectional promoter during cell cycle progression. Biochem J 1997; 325(Part 1): 277-286.
    • (1997) Biochem J , vol.325 , Issue.PART 1 , pp. 277-286
    • Guarguaglini, G.1    Battistoni, A.2    Pittoggi, C.3    Di Matteo, G.4    Di Fiore, B.5    Lavia, P.6
  • 23
    • 0032863876 scopus 로고    scopus 로고
    • The genomic organization of the histone clusters on human 6p213
    • Ahn J, Gruen JR. The genomic organization of the histone clusters on human 6p213. Mamm Genome 1999; 10: 768-770.
    • (1999) Mamm Genome , vol.10 , pp. 768-770
    • Ahn, J.1    Gruen, J.R.2
  • 24
    • 0037208893 scopus 로고    scopus 로고
    • Genomic structure of the human mitochon-drial chaperonin genes: HSP60 and HSP10 are localised head to head on chromosome 2 separated by a bidirectional promoter
    • Hansen JJ, Bross P, Westergaard M, Nielsen MN, Eiberg H, Borglum AD et al. Genomic structure of the human mitochon-drial chaperonin genes: HSP60 and HSP10 are localised head to head on chromosome 2 separated by a bidirectional promoter. Hum Genet 2003; 112: 71-77.
    • (2003) Hum Genet , vol.112 , pp. 71-77
    • Hansen, J.J.1    Bross, P.2    Westergaard, M.3    Nielsen, M.N.4    Eiberg, H.5    Borglum, A.D.6
  • 25
    • 33847625884 scopus 로고    scopus 로고
    • A promoter with bidirectional activity is located between TLX1/HOX11 and a divergently transcribed novel human gene
    • Greene WK, Sontani Y, Sharp MA, Dunn DS, Kees UR, Bellgard MI. A promoter with bidirectional activity is located between TLX1/HOX11 and a divergently transcribed novel human gene. Gene 2007; 391: 223-232.
    • (2007) Gene , vol.391 , pp. 223-232
    • Greene, W.K.1    Sontani, Y.2    Sharp, M.A.3    Dunn, D.S.4    Kees, U.R.5    Bellgard, M.I.6
  • 26
    • 45149112416 scopus 로고    scopus 로고
    • Prediction-based approaches to characterize bidirectional promoters in the mammalian genome
    • Yang MQ, Elnitski LL. Prediction-based approaches to characterize bidirectional promoters in the mammalian genome. BMC Genomics 2008; 9(Suppl 1): S2.
    • (2008) BMC Genomics , vol.9 , Issue.SUPPL. 1
    • Yang, M.Q.1    Elnitski, L.L.2
  • 27
    • 29044435014 scopus 로고    scopus 로고
    • A novel bidirectional expression system for simultaneous expression of both the protein-coding genes and short hairpin RNAs in mammalian cells
    • Hung CF, Cheng TL, Wu RH, Teng CF, Chang WT. A novel bidirectional expression system for simultaneous expression of both the protein-coding genes and short hairpin RNAs in mammalian cells. Biochem Biophys Res Commun 2006; 339: 1035-1042.
    • (2006) Biochem Biophys Res Commun , vol.339 , pp. 1035-1042
    • Hung, C.F.1    Cheng, T.L.2    Wu, R.H.3    Teng, C.F.4    Chang, W.T.5
  • 29
    • 51349158298 scopus 로고    scopus 로고
    • Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients
    • Howe SJ, Mansour MR, Schwarzwaelder K, Bartholomae C, Hubank M, Kempski H et al. Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients. J Clin Invest 2008; 118: 3143-3150.
    • (2008) J Clin Invest , vol.118 , pp. 3143-3150
    • Howe, S.J.1    Mansour, M.R.2    Schwarzwaelder, K.3    Bartholomae, C.4    Hubank, M.5    Kempski, H.6
  • 31
    • 0035437131 scopus 로고    scopus 로고
    • Gene transfer into murine hematopoietic stem cells with helper-free foamy virus vectors
    • Vassilopoulos G, Trobridge G, Josephson NC, Russell DW. Gene transfer into murine hematopoietic stem cells with helper-free foamy virus vectors. Blood 2001; 98: 604-609.
    • (2001) Blood , vol.98 , pp. 604-609
    • Vassilopoulos, G.1    Trobridge, G.2    Josephson, N.C.3    Russell, D.W.4
  • 32
    • 1242296984 scopus 로고    scopus 로고
    • Cell cycle requirements for transduc-tion by foamy virus vectors compared to those of oncovirus and lentivirus vectors
    • Trobridge G, Russell DW. Cell cycle requirements for transduc-tion by foamy virus vectors compared to those of oncovirus and lentivirus vectors. J Virol 2004; 78: 2327-2335.
    • (2004) J Virol , vol.78 , pp. 2327-2335
    • Trobridge, G.1    Russell, D.W.2
  • 33
    • 39849099656 scopus 로고    scopus 로고
    • A rapid and quantitative assay for measuring neighboring gene activation by vector proviruses
    • Hendrie PC, Huo Y, Stolitenko RB, Russell DW. A rapid and quantitative assay for measuring neighboring gene activation by vector proviruses. Mol Ther 2008; 16: 534-540.
    • (2008) Mol Ther , vol.16 , pp. 534-540
    • Hendrie, P.C.1    Huo, Y.2    Stolitenko, R.B.3    Russell, D.W.4
  • 35
    • 33645734405 scopus 로고    scopus 로고
    • Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1
    • Ott MG, Schmidt M, Schwarzwaelder K, Stein S, Siler U, Koehl U et al. Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1. Nat Med 2006; 12: 401-409.
    • (2006) Nat Med , vol.12 , pp. 401-409
    • Ott, M.G.1    Schmidt, M.2    Schwarzwaelder, K.3    Stein, S.4    Siler, U.5    Koehl, U.6
  • 37
    • 0023647927 scopus 로고
    • Position-dependent sequence elements downstream of AAUAAA are required for efficient rabbit beta-globin mRNA 3 end formation
    • Gil A, Proudfoot NJ. Position-dependent sequence elements downstream of AAUAAA are required for efficient rabbit beta-globin mRNA 3 end formation. Cell 1987; 49: 399-406.
    • (1987) Cell , vol.49 , pp. 399-406
    • Gil, A.1    Proudfoot, N.J.2
  • 39
    • 23844493606 scopus 로고    scopus 로고
    • Comparison of HIV-and EIAV-based vectors on their efficiency in transducing murine and human hematopoietic repopulating cells
    • Siapati EK, Bigger BW, Miskin J, Chipchase D, Parsley KL, Mitrophanous K et al. Comparison of HIV-and EIAV-based vectors on their efficiency in transducing murine and human hematopoietic repopulating cells. Mol Ther 2005; 12: 537-546.
    • (2005) Mol Ther , vol.12 , pp. 537-546
    • Siapati, E.K.1    Bigger, B.W.2    Miskin, J.3    Chipchase, D.4    Parsley, K.L.5    Mitrophanous, K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.