Gene transfer into murine hematopoietic stem cells with helper-free foamy virus vectors

Blood

Volumn 98, Issue 3, 2001, Pages 604-609

  Vassilopoulos, George ^a   Trobridge, Grant ^a   Josephson, Neil C ^a   Russell, David W ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN; RETROVIRUS VECTOR; VIRUS VECTOR;

ANIMAL CELL; ARTICLE; BONE MARROW CELL; BONE MARROW TRANSPLANTATION; CELL LINEAGE; CONTROLLED STUDY; EMBRYO; GENE SILENCING; GENE TRANSFER; GENETIC CODE; HEMATOPOIETIC STEM CELL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; SPUMA VIRUS; STEM CELL; TRANSGENE; UMBILICAL CORD BLOOD; VIRAL GENE DELIVERY SYSTEM; VIRAL GENE THERAPY;

EID: 0035437131     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.V98.3.604     Document Type: Article

References (43)

1. Riviere I, Brose K, Mulligan RC. Effects of retroviral vector design on expression of human adenosine deaminase in murine bone marrow transplant recipients engrafted with genetically modified cells. Proc Natl Acad Sci U S A. 1995;92:6733-6737.
2. Persons DA, Allay JA, Allay ER, et al. Retroviral-mediated transfer of the green fluorescent protein gene into murine hematopoietic cells facilitates scoring and selection of transduced progenitors in vitro and identification of genetically modified cells in vivo. Blood. 1997;90:1777-1786.
3. Halene S, Wang L, Cooper RM, Bockstoce DC, Robbins PB, Kohn DB. Improved expression in hematopoietic and lymphoid cells in mice after transplantation of bone marrow transduced with a modified retroviral vector. Blood, 1999;94:3349-3357.
4. Orlic D, Girard LJ, Jordan CT, Anderson SM, Cline AP, Bodine DM, The level of mRNA encoding the amphotropic retrovirus receptor in mouse and human hematopoietic stem cells is low and correlates with the efficiency of retrovirus transduction. Proc Natl Acad Sci U S A. 1996;93:11097-11102.
5. Roe T, Reynolds TC, Yu G, Brown PO. Integration of murine leukemia virus DNA depends on mitosis. EMBO J. 1993;12:2099-2108.
6. + cells that mediate long-term engraftment of NOD/SCID mice by HIV vectors. Science. 1999;283:682-686.
7. May C, Rivella S, Callegari J, et al. Therapeutic haemoglobin synthesis in β-thalassaemic mice expressing lentivirus-encoded human β-globin. Nature. 2000;406:82-86.
8. Kiem HP, Heyward S, Winkler A, et al. Gene transfer into marrow repopulating cells: comparison between amphotropic and gibbon ape leukemia virus pseudotyped retroviral vectors in a competitive repopulation assay in baboons. Blood. 1997;90:4638-4645.
9. Bieniasz PD, Erlwein O, Aguzzi A, Rethwilm A, McClure MO. Gene transfer using replication-defective human foamy virus vectors. Virology. 1997;235:65-72.
10. Russell DW, Miller AD. Foamy virus vectors. J Virol. 1996;70:217-222.
11. Schmidt M, Rethwilm A. Replicating foamy virus-based vectors directing high level expression of foreign genes. Virology. 1995;210:167-178.
12. Hirata RK, Miller AD, Andrews RG, Russell DW. Transduction of hematopoietic cells by foamy virus vectors. Blood. 1996;88:3654-3661.
13. Flugel RM. Spumaviruses: a group of complex retroviruses. J Acquir Immune Defic Syndr. 1991;4:739-750.
14. Hooks JJ, Gibbs CJ Jr. The foamy viruses. Bacteriol Rev. 1975;39:169-185.
15. Ali M, Taylor GP, Pitman RJ, et al. No evidence of antibody to human foamy virus in widespread human populations. AIDS Res Hum Retroviruses. 1996;12:1473-1483.
16. Brown P, Nemo G, Gajdusek DC. Human foamy virus: further characterization, seroepidemiology, and relationship to chimpanzee foamy viruses. J Infect Dis. 1978;137:421-427.
17. Schweizer M, Turek R, Hahn H, et al. Markers of foamy virus infections in monkeys, apes, and accidentally infected humans: appropriate testing fails to confirm suspected foamy virus prevalence in humans. AIDS Res Hum Retroviruses. 1995;11:161-170.
18. Venkatesh LK, Theodorakis PA, Chinnadurai G. Distinct cis-acting regions in U3 regulate transactivation of the human spumaretrovirus long terminal repeat by the viral bell gene product. Nucleic Acids Res. 1991;19:3661-3666.
19. Rethwilm A, Erlwein O, Baunach G, Maurer B, ter Meulen V. The transcriptional transactivator of human foamy virus maps to the bel 1 genomic region. Proc Natl Acad Sci U S A. 1991;88:941-945.
20. Keller A, Partin KM, Lochelt M, Bannert H, Flugel RM, Cullen BR. Characterization of the transcriptional trans activator of human foamy retrovirus. J Virol. 1991;65:2589-2594.
21. Baunach G, Maurer B, Hahn H, Kranz M, Rethwilm A. Functional analysis of human foamy virus accessory reading frames. J Virol. 1993;67:5411-5418.
22. Yu SF, Linial ML. Analysis of the role of the bel and bet open reading frames of human foamy virus by using a new quantitative assay. J Virol. 1993;67:6618-6624.
23. Yu SF, Baldwin DN, Gwynn SR, Yendapalli S, Linial ML. Human foamy virus replication: a pathway distinct from that of retroviruses and hepadnaviruses. Science. 1996;271:1579-1582.
24. Moebes A, Enssle J, Bieniasz PD, et al. Human foamy virus reverse transcription that occurs late in the viral replication cycle. J Virol. 1997;71:7305-7311.
25. Trobridge GD, Russell DW. Helper-free foamy virus vectors. Hum Gene Ther. 1998;9:2517-2525.
26. Macpherson I, Stoker M. Polyoma transformation of hamster cell clones-an investigation of genetic factors affecting cell competence. Virology. 1962;16:147-151.
27. DuBridge RB, Tang P, Hsia HC, Leong PM, Miller JH, Calos MP. Analysis of mutation in human cells by using an Epstein-Barr virus shuttle system. Mol Cell Biol. 1987;7:379-387.
28. Hawley RG, Lieu FH, Fong AZ, Hawley TS. Versatile retroviral vectors for potential use in gene therapy. Gene Ther. 1994;1:136-138.
29. Sambrook J, Fritsch EF, Maniatis T, eds. Molecular Cloning. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press; 1989.
30. Tanaka T, Suda T, Suda J, et al. Stimulatory effects of granulocyte colony-stimulating factor on colony-forming units-spleen (CFU-S) differentiation and pre-CFU-S proliferation in mice. Blood. 1991;77:2597-2602,
31. Hanenberg H, Xiao XL, Dilloo D, Hashino K, Kato I, Williams DA. Colocalization of retrovirus and target cells on specific fibronectin fragments increases genetic transduction of mammalian cells. Nat Med. 1996;2:876-882.
32. Moritz T, Patel VP, Williams DA. Bone marrow extracellular matrix molecules improve gene transfer into human hematopoietic cells via retroviral vectors. J Clin Invest. 1994;93:1451-1457.
33. Bodine DM, Seidel NE, Gale MS, Nienhuis AW, Orlic D. Efficient retrovirus transduction of mouse pluripotent hematopoietic stem cells mobilized into the peripheral blood by treatment with granulocyte colony-stimulating factor and stem cell factor. Blood. 1994;84:1482-1491.
34. Heberling RL, Kalter SS. Isolation of foamy viruses from baboon (Papio cynocephalus) tissues. Am J Epidemiol. 1975;102:25-29.
35. McClure MO, Bieniasz PD, Schulz TF, et al. Isolation of a new foamy retrovirus from orangutans. J Virol. 1994;68:7124-7130.
36. Rhodes Feuillette A, Saal F, Lasneret J, Dubouch P, P'Eries J. Isolation and characterization of a new simian foamy virus serotype from lymphocytes of a Papio cynocephalus baboon. J Med Primatol. 1979;8:308-320.
37. Saib A, Puvion Dutilleul F, Schmid M, P'Eries J, de Th'e H. Nuclear targeting of incoming human foamy virus Gag proteins involves a centriolar step. J Virol. 1997;71:1155-1161.
38. Hill CL, Bieniasz PD, McClure MO. Properties of human foamy virus relevant to its development as a vector for gene therapy. J Gen Virol. 1999;80:2003-2009.
39. Palmer TD, Rosman GJ, Osborne WR, Miller AD. Genetically modified skin fibroblasts persist long after transplantation but gradually inactivate introduced genes. Proc Natl Acad Sci U S A. 1991;88:1330-1334.
40. Challita PM, Kohn DB. Lack of expression from a retroviral vector after transduction of murine hematopoietic stem cells is associated with methylation in vivo. Proc Natl Acad Sci U S A. 1994;91:2567-2571.
41. Lange C, Blankenstein T. Loss of retroviral gene expression in bone marrow reconstituted mice correlates with down-regulation of gene expression in long-term culture initiating cells. Gene Ther. 1997;4:303-308.
42. Heinkelein M, Schmidt M, Fischer N, et al. Characterization of a cis-acting sequence in the pol region required to transfer human foamy virus vectors. J Virol. 1998;72:6307-6314.
43. Erlwein O, Bieniasz PD, McClure MO. Sequences in pol are required for transfer of human foamy virus-based vectors. J Virol. 1998;72:5510-5516.