Impact of environmental chemicals on key transcription regulators and correlation to toxicity end points within EPA's toxcast program

Chemical Research in Toxicology

Volumn 23, Issue 3, 2010, Pages 578-590

  Martin, Matthew T ^a   Dix, David J ^a   Judson, Richard S ^a   Kavlock, Robert J ^a   Reif, David M ^a   Richard, Ann M ^a   Rotroff, Daniel M ^b   Romanov, Sergei ^d   Medvedev, Alexander ^c   Poltoratskaya, Natalia ^c   Gambarian, Maria ^c   Moeser, Matt ^c   Makarov, Sergei S ^c   Houck, Keith A ^a  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

^c Attagene Inc   (United States)

^d Nanosyn Biology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4,4' ISOPROPYLIDENEDIPHENOL; ALACHLOR; CELL NUCLEUS RECEPTOR; DICHLORVOS; DIQUAT; ENILCONAZOLE; ENVIRONMENTAL CHEMICAL; METHOXYCHLOR; METRIFONATE; PERFLUOROOCTANOIC ACID; PHTHALIC ACID BIS(2 ETHYLHEXYL) ESTER; ROSIGLITAZONE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NRF2;

ANIMAL EXPERIMENT; ARTICLE; BIOSENSOR; CELL STRAIN HEPG2; CONTROLLED STUDY; CYTOTOXICITY; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL IMPACT; GENE REGULATORY NETWORK; HEPATOMA CELL; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PREDICTION; RAT; TOXICITY; TRANSCRIPTION REGULATION;

ANIMALS; BIOSENSING TECHNIQUES; ENVIRONMENTAL POLLUTANTS; HEP G2 CELLS; RABBITS; RATS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RESPONSE ELEMENTS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 77949413202     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx900325g     Document Type: Article

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