HHQ and PQS, two Pseudomonas aeruginosa quorum-sensing molecules, down-regulate the innate immune responses through the nuclear factor-κB pathway

Immunology

Volumn 129, Issue 4, 2010, Pages 578-588

  Kim, Kiwan ^a   Kim, Young Uk ^a   Koh, Byung Hee ^a   Hwang, Soo Seok ^a   Kim, Seol Hee ^a   Lépine, Francois ^b   Cho, You Hee ^a   Lee, Gap Ryol ^a  

^a Sogang University   (South Korea)

^b INRS INSTITUT ARMAND FRAPPIER   (Canada)

Author keywords

4 hydroxy 2 alkylquinolines; Immune evasion; Innate cytokine; Innate immunity; Macrophage; Nuclear factor B; Quorum sensing

Indexed keywords

2 HEPTYL 3,4 DIHYDROXYQUINOLINE; 4 HYDROXY 2 HEPTYLQUINOLINE; CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING SITE; C57BL 6 MOUSE; CELL CULTURE; CELL LINE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; GENE TARGETING; HUMAN; HUMAN CELL; IN VIVO STUDY; INNATE IMMUNITY; LUNG LAVAGE; LUNG PARENCHYMA; MACROPHAGE; MAMMAL; MONOCYTE; MOUSE; MUTANT; NONHUMAN; PATHOGENICITY; PRIORITY JOURNAL; PROTEIN DEGRADATION; PSEUDOMONAS AERUGINOSA; QUORUM SENSING; SUPERNATANT; WILD TYPE;

ANIMALS; CELL SURVIVAL; CELLS, CULTURED; DISEASE MODELS, ANIMAL; DOWN-REGULATION; HYDROXYQUINOLINES; IMMUNITY, INNATE; MICE; MICE, INBRED C57BL; NF-KAPPA B; PSEUDOMONAS AERUGINOSA; QUORUM SENSING;

EID: 77949409691     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/j.1365-2567.2009.03160.x     Document Type: Article

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