Hydrophobicity - Shake flasks, protein folding and drug discovery

Current Topics in Medicinal Chemistry

Volumn 10, Issue 1, 2010, Pages 67-83

  Sarkar, Aurijit ^a   Kellogg, Glen E ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

Drug Design; HINT; Hydrophobic Interactions; Hydrophobicity; Hydrophobicity Scales; LogP; Protein Folding; QSAR

Indexed keywords

AMINO ACID; ANESTHETIC AGENT; HYDROCARBON; NARCOTIC AGENT; PROTEIN; QUINIDINE; WATER;

CIRCULAR DICHROISM; DRUG DESIGN; DRUG STRUCTURE; GEOMETRY; HYDROPHOBICITY; LIGAND BINDING; MOLECULAR INTERACTION; MOLECULE; PARTITION COEFFICIENT; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; QUANTITATIVE STRUCTURE ACTIVITY RELATION; REVIEW; SOLUBILITY; TECHNOLOGY; THREE DIMENSIONAL IMAGING; X RAY CRYSTALLOGRAPHY;

DRUG DESIGN; DRUG DISCOVERY; HYDROPHOBICITY; PHARMACEUTICAL PREPARATIONS; PROTEIN FOLDING; PROTEINS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 77949347414     PISSN: 15680266     EISSN: None     Source Type: Journal    
DOI: 10.2174/156802610790232233     Document Type: Review

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