Activation of the hexosamine pathway by glucosamine in vivo induces insulin resistance of early postreceptor insulin signaling events in skeletal muscle

Diabetes

Volumn 48, Issue 8, 1999, Pages 1562-1571

  Patti, Mary Elizabeth ^a   Virkamäki, Antti ^b   Landaker, Edwin J ^a   Kahn, C Ronald ^a   Yki Järvinen, Hannele ^c  

^a JOSLIN DIABETES CENTER   (United States)

^b MINERVA FOUNDATION INSTITUTE FOR MEDICAL RESEARCH   (Finland)

^c UNIVERSITY OF HELSINKI   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSAMINE; GLYCOGEN; HEXOSAMINE; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; PHOSPHATIDYLINOSITOL 3 KINASE; URIDINE DIPHOSPHATE N ACETYLGLUCOSAMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARBOHYDRATE METABOLISM; CONTROLLED STUDY; ENZYME ACTIVITY; GLUCOSE CLAMP TECHNIQUE; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; GLYCOGEN METABOLISM; GLYCOGEN MUSCLE LEVEL; HYPERGLYCEMIA; INSULIN RESISTANCE; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; RAT; SIGNAL TRANSDUCTION; SKELETAL MUSCLE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; ENZYME ACTIVATION; GLUCOSAMINE; GLYCOSYLATION; HEXOSAMINES; INSULIN; INSULIN RESISTANCE; LIPID METABOLISM; MALE; MUSCLE, SKELETAL; PHOSPHORYLATION; PHOSPHOTRANSFERASES; PROTEIN ISOFORMS; RATS; RATS, WISTAR; RECEPTOR, INSULIN; SIGNAL TRANSDUCTION; TYROSINE;

EID: 0344298921     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.48.8.1562     Document Type: Article

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