메뉴 건너뛰기




Volumn 56, Issue 1, 2010, Pages 19-26

Polymorphisms of genes for brain-derived neurotrophic factor, methylenetetrahydrofolate reductase, tyrosine hydroxylase, and endothelial nitric oxide synthase in depression and metabolic syndrome

Author keywords

BDNF; Depression; Gene polymorphism; Metabolic syndrome

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); BRAIN DERIVED NEUROTROPHIC FACTOR; ENDOTHELIAL NITRIC OXIDE SYNTHASE; METHIONINE; TYROSINE 3 MONOOXYGENASE; VALINE; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); MICROSATELLITE DNA;

EID: 77949286063     PISSN: 00155500     EISSN: 25337602     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (26)

References (67)
  • 1
    • 33645978121 scopus 로고    scopus 로고
    • Metabolic syndrome - a new world-wide definition. A Consensus Statement from the International Diabetes Federation
    • Alberti, K. G., Zimmet, P., Shaw, J. (2006) Metabolic syndrome - a new world-wide definition. A Consensus Statement from the International Diabetes Federation. Diabet. Med. 23, 469-480.
    • (2006) Diabet. Med , vol.23 , pp. 469-480
    • Alberti, K.G.1    Zimmet, P.2    Shaw, J.3
  • 2
    • 0033079596 scopus 로고    scopus 로고
    • Neurotrophins and depression
    • Altar, C. A. (1999) Neurotrophins and depression. Trends Pharmacol. Sci. 20, 59-61.
    • (1999) Trends Pharmacol. Sci , vol.20 , pp. 59-61
    • Altar, C.A.1
  • 3
    • 0004235298 scopus 로고
    • American Psychiatric Association , Fourth Edition, American Psychiatric Press, Washington, DC
    • American Psychiatric Association (1994) Diagnostic and Statistical Manual for Mental Disorders - Fourth Edition, American Psychiatric Press, Washington, DC.
    • (1994) Diagnostic and Statistical Manual for Mental Disorders
  • 7
    • 0037384215 scopus 로고    scopus 로고
    • 5,10-Methylenetetrahydrofolate reductase 677C→T and 1298A→C mutations are genetic determinants of elevated homocysteine
    • Castro, R., Rivera, I., Ravasco, P., Jakobs, C., Blom, H. J., Camilo, M. E., De Almeida, I. T. (2003) 5,10-Methylenetetrahydrofolate reductase 677C→T and 1298A→C mutations are genetic determinants of elevated homocysteine. Q. J. Med. 96, 297-303.
    • (2003) Q. J. Med , vol.96 , pp. 297-303
    • Castro, R.1    Rivera, I.2    Ravasco, P.3    Jakobs, C.4    Blom, H.J.5    Camilo, M.E.6    De Almeida, I.T.7
  • 9
    • 2342550552 scopus 로고    scopus 로고
    • Variant brain-derived neurotrophic factor (BDNF) (Met66) alters the intracellular trafficking and activity-dependent secretion of wildtype BDNF in neurosecretory cells and cortical neurons
    • Chen, Z. Y., Patel, P. D., Sant, G., Meng, C. X., Teng, K. K., Hempstead, B. L., Lee, F. S. (2004) Variant brain-derived neurotrophic factor (BDNF) (Met66) alters the intracellular trafficking and activity-dependent secretion of wildtype BDNF in neurosecretory cells and cortical neurons. J. Neurosci. 24, 4401-4411.
    • (2004) J. Neurosci , vol.24 , pp. 4401-4411
    • Chen, Z.Y.1    Patel, P.D.2    Sant, G.3    Meng, C.X.4    Teng, K.K.5    Hempstead, B.L.6    Lee, F.S.7
  • 11
    • 33750371336 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor gene polymorphism (Val66Met) and citalopram response in major depressive disorder
    • Choi, M. J., Kang, R. H., Lim, S. W., Oh, K. S., Lee, M. S. (2006) Brain-derived neurotrophic factor gene polymorphism (Val66Met) and citalopram response in major depressive disorder. Brain Res. 1118, 176-182.
    • (2006) Brain Res , vol.1118 , pp. 176-182
    • Choi, M.J.1    Kang, R.H.2    Lim, S.W.3    Oh, K.S.4    Lee, M.S.5
  • 12
    • 3042609836 scopus 로고    scopus 로고
    • Decreased plasma nitric oxide metabolites and platelet nitric oxide synthase activity in patients with major depression
    • Chrapko, W. E., Juracz, P., Radomski, M. W., Lara, N., Archer, S., Le Melledo, J. M. (2004) Decreased plasma nitric oxide metabolites and platelet nitric oxide synthase activity in patients with major depression. Biol. Psychiatry 56, 129-134.
    • (2004) Biol. Psychiatry , vol.56 , pp. 129-134
    • Chrapko, W.E.1    Juracz, P.2    Radomski, M.W.3    Lara, N.4    Archer, S.5    Le Melledo, J.M.6
  • 13
    • 85069252537 scopus 로고    scopus 로고
    • Czech Health Statistics Yearbook, Prague, Czech Republic
    • Czech Health Statistics Yearbook 2006, ÚZIS ČR, Prague, Czech Republic (2007).
    • (2006) ÚZIS ČR
  • 14
    • 3242745166 scopus 로고    scopus 로고
    • Depression: A case of neuronal life and death?
    • Duman, R. S. (2004) Depression: a case of neuronal life and death? Biol. Psychiatry 56, 140-145.
    • (2004) Biol. Psychiatry , vol.56 , pp. 140-145
    • Duman, R.S.1
  • 15
    • 0042154427 scopus 로고    scopus 로고
    • Altered gene expression of brain-derived neurotrophic factor and receptor tyrosine kinase B in postmortem brain of suicide subjects
    • Dwivedi, Y., Rizavi, H. S., Conley, R. R., Roberts, R. C., Tamminga, C. A., Pandey, G. N. (2003) Altered gene expression of brain-derived neurotrophic factor and receptor tyrosine kinase B in postmortem brain of suicide subjects. Arch. Gen. Psychiatry 60, 804-815.
    • (2003) Arch. Gen. Psychiatry , vol.60 , pp. 804-815
    • Dwivedi, Y.1    Rizavi, H.S.2    Conley, R.R.3    Roberts, R.C.4    Tamminga, C.A.5    Pandey, G.N.6
  • 16
    • 36849066949 scopus 로고    scopus 로고
    • Metabolic syndrome and insulin resistance in schizophrenia patients receiving antipsychotics genotyped for the methylenetetrahydrofolate reductase (MTHFR) 677C/T and 1298A/C variants
    • Ellingrod, V. L., Miller del, D., Taylor, S. F., Moline, J., Holman, T., Kerr, J. (2008) Metabolic syndrome and insulin resistance in schizophrenia patients receiving antipsychotics genotyped for the methylenetetrahydrofolate reductase (MTHFR) 677C/T and 1298A/C variants. Schizophr. Res. 98, 47-54.
    • (2008) Schizophr. Res , vol.98 , pp. 47-54
    • Ellingrod, V.L.1    Miller del, D.2    Taylor, S.F.3    Moline, J.4    Holman, T.5    Kerr, J.6
  • 21
    • 33748349409 scopus 로고    scopus 로고
    • Significance of hyperhomocysteinemia
    • Herrmann, W. (2006) Significance of hyperhomocysteinemia. Clin. Lab. 52, 367-374.
    • (2006) Clin. Lab , vol.52 , pp. 367-374
    • Herrmann, W.1
  • 22
    • 0347380124 scopus 로고    scopus 로고
    • Association study of a brain-derived neurotrophic-factor genetic polymorphism and mood disorders, age of onset and suicidal behavior
    • Hong, C. J., Huo, S. J., Yen, F. C., Tung, C. L., Pan, G. M., Tsai, S. J. (2003) Association study of a brain-derived neurotrophic-factor genetic polymorphism and mood disorders, age of onset and suicidal behavior. Neuropsychobiology 48, 186-189.
    • (2003) Neuropsychobiology , vol.48 , pp. 186-189
    • Hong, C.J.1    Huo, S.J.2    Yen, F.C.3    Tung, C.L.4    Pan, G.M.5    Tsai, S.J.6
  • 24
    • 0034811586 scopus 로고    scopus 로고
    • Association of the Glu298Asp polymorphism in the endothelial nitric oxide synthase gene with essential hypertension resistant to conventional therapy
    • Jáchymová, M., Horký, K., Bultas, J., Kožich, V., Jindra, A., Peleška, J., Martásek, P. (2001) Association of the Glu298Asp polymorphism in the endothelial nitric oxide synthase gene with essential hypertension resistant to conventional therapy. Biochem. Biophys. Res. Comm. 284, 426-430.
    • (2001) Biochem. Biophys. Res. Comm , vol.284 , pp. 426-430
    • Jáchymová, M.1    Horký, K.2    Bultas, J.3    Kožich, V.4    Jindra, A.5    Peleška, J.6    Martásek, P.7
  • 25
    • 0034538597 scopus 로고    scopus 로고
    • Association analysis of two tyrosine hydroxylase gene polymorphisms in normotensive offspring from hypertensive families
    • Jindra, A., Jáchymová, M., Horký, K., Peleška, J., Umnerová, V., Bultas, J., Šavlí ková, J. (2000) Association analysis of two tyrosine hydroxylase gene polymorphisms in normotensive offspring from hypertensive families. Blood Press. 9, 250-254.
    • (2000) Blood Press , vol.9 , pp. 250-254
    • Jindra, A.1    Jáchymová, M.2    Horký, K.3    Peleška, J.4    Umnerová, V.5    Bultas, J.6    Šavlí ková, J.7
  • 26
    • 0036202956 scopus 로고    scopus 로고
    • Decreased serum brain-derived neurotrophic factor levels in major depressed patients
    • Karege, F., Perret, G., Bondolfi, G., Schwald, M., Bertschy, G., Aubry, J. M. (2002). Decreased serum brain-derived neurotrophic factor levels in major depressed patients. Psychiatry Res. 109, 143-148.
    • (2002) Psychiatry Res , vol.109 , pp. 143-148
    • Karege, F.1    Perret, G.2    Bondolfi, G.3    Schwald, M.4    Bertschy, G.5    Aubry, J.M.6
  • 28
    • 0142042983 scopus 로고    scopus 로고
    • Depressed new neurons - adult hippocampal neurogenesis and a cellular plasticity hypothesis of major depression
    • Kempermann, G., Kronenberg, G. (2003) Depressed new neurons - adult hippocampal neurogenesis and a cellular plasticity hypothesis of major depression. Biol. Psychiatry 54, 499-503.
    • (2003) Biol. Psychiatry , vol.54 , pp. 499-503
    • Kempermann, G.1    Kronenberg, G.2
  • 29
    • 33846551159 scopus 로고    scopus 로고
    • Distribution of 1298 A > C polymorphism of methylenetetrahydrofolate reductase gene in patients with bipolar disorder and schizophrenia
    • Kempisty, B., Bober, A., Łuczak, M., Czerski, P., Szczepankiewicz, A., Hauser, J., Jagodziński, P. P. (2007) Distribution of 1298 A > C polymorphism of methylenetetrahydrofolate reductase gene in patients with bipolar disorder and schizophrenia. Eur. Psychiatry 22, 39-43.
    • (2007) Eur. Psychiatry , vol.22 , pp. 39-43
    • Kempisty, B.1    Bober, A.2    Łuczak, M.3    Czerski, P.4    Szczepankiewicz, A.5    Hauser, J.6    Jagodziński, P.P.7
  • 30
    • 15244360210 scopus 로고    scopus 로고
    • TH01, a tetrameric short tandem repeat locus in the tyrosine hydroxylase gene: Association with myocardial hypertrophy and death from myocardial infarction?
    • Klintschar, M., Immel, U. D., Stiller, D., Kleiber, M. (2005) TH01, a tetrameric short tandem repeat locus in the tyrosine hydroxylase gene: association with myocardial hypertrophy and death from myocardial infarction? Dis. Markers 21, 9-13.
    • (2005) Dis. Markers , vol.21 , pp. 9-13
    • Klintschar, M.1    Immel, U.D.2    Stiller, D.3    Kleiber, M.4
  • 32
    • 0038798590 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor gene and schizophrenia: Polymorphism screening and association analysis
    • Kunugi, H., Nanko, S., Hirasawa, H., Kato, N., Nabika, T., Kobayashi, S. (2003) Brain-derived neurotrophic factor gene and schizophrenia: polymorphism screening and association analysis. Schizophr. Res. 62, 281-283.
    • (2003) Schizophr. Res , vol.62 , pp. 281-283
    • Kunugi, H.1    Nanko, S.2    Hirasawa, H.3    Kato, N.4    Nabika, T.5    Kobayashi, S.6
  • 34
    • 11344265673 scopus 로고    scopus 로고
    • Nitric oxide: A key player in the relation between cardiovascular disease and major depressive disorder?
    • Le Mellédo, J.-M., Mahil, N., Baker, G. B. (2004) Nitric oxide: A key player in the relation between cardiovascular disease and major depressive disorder? J. Psychiatry Neurosci. 29, 414-416.
    • (2004) J. Psychiatry Neurosci , vol.29 , pp. 414-416
    • Le Mellédo, J.-M.1    Mahil, N.2    Baker, G.B.3
  • 36
    • 3042609839 scopus 로고    scopus 로고
    • Gene-environment interaction and the genetics of depression
    • Lesch, K. P. (2004) Gene-environment interaction and the genetics of depression. J. Psychiatry Neurosci. 29, 174-182.
    • (2004) J. Psychiatry Neurosci , vol.29 , pp. 174-182
    • Lesch, K.P.1
  • 37
  • 38
    • 33745726353 scopus 로고    scopus 로고
    • The genetics of depression: A review
    • Levinson, D. F. (2006) The genetics of depression: a review. Biol. Psychiatry 60, 84-92.
    • (2006) Biol. Psychiatry , vol.60 , pp. 84-92
    • Levinson, D.F.1
  • 39
    • 33645527632 scopus 로고    scopus 로고
    • The thermolabile variant of MTHFR is associated with depression in the British Women's Heart and Health Study and a meta-analysis
    • Lewis, S. J., Lawlor, D. A., Davey Smith, G., Araya, R., Timpson, N., Day, I. N. M., Ebrahim, S. (2006) The thermolabile variant of MTHFR is associated with depression in the British Women's Heart and Health Study and a meta-analysis. Mol. Psychiatry 11, 352-360.
    • (2006) Mol. Psychiatry , vol.11 , pp. 352-360
    • Lewis, S.J.1    Lawlor, D.A.2    Davey Smith, G.3    Araya, R.4    Timpson, N.5    Day, I.N.M.6    Ebrahim, S.7
  • 43
    • 17444413709 scopus 로고    scopus 로고
    • Glucocorticoids, depression and mood disorders: Structural remodeling in the brain
    • Mc Ewen, B. S. (2005) Glucocorticoids, depression and mood disorders: structural remodeling in the brain. Metabolism 54 (Suppl 1), 20-23.
    • (2005) Metabolism , vol.54 , Issue.SUPPL. 1 , pp. 20-23
    • Mc Ewen, B.S.1
  • 44
    • 0030040316 scopus 로고    scopus 로고
    • A hospital-based twin register of the heritability of DSM-IV unipolar depression
    • McGuffin, P., Katz, R., Watkins, S., Rutherford, J. (1996) A hospital-based twin register of the heritability of DSM-IV unipolar depression. Arch. Gen. Psychiatry 53, 129-136.
    • (1996) Arch. Gen. Psychiatry , vol.53 , pp. 129-136
    • McGuffin, P.1    Katz, R.2    Watkins, S.3    Rutherford, J.4
  • 45
    • 0024284028 scopus 로고
    • A simple salting out extraction DNA from human nucleated cells
    • Miller, S. A., Dykes, D. D., Polesky, H. F. (1988) A simple salting out extraction DNA from human nucleated cells. Nucleic Acids Res. 16, 1215.
    • (1988) Nucleic Acids Res , vol.16 , pp. 1215
    • Miller, S.A.1    Dykes, D.D.2    Polesky, H.F.3
  • 47
    • 0031822289 scopus 로고    scopus 로고
    • The relationship of depression to cardiovascular disease: Epidemiology, biology, and treatment
    • Musselman, D. L., Evans, D. L., Nemeroff, C. B. (1998) The relationship of depression to cardiovascular disease: epidemiology, biology, and treatment. Arch. Gen. Psychiatry 55, 580-592.
    • (1998) Arch. Gen. Psychiatry , vol.55 , pp. 580-592
    • Musselman, D.L.1    Evans, D.L.2    Nemeroff, C.B.3
  • 48
    • 0141832614 scopus 로고    scopus 로고
    • Relationship of depression to diabetes types 1 and 2: Epidemiology, biology, and treatment
    • Musselman, D. L., Betan, E., Larsen, H., Phillips, L. S. (2003) Relationship of depression to diabetes types 1 and 2: epidemiology, biology, and treatment. Biol. Psychiatry 54, 317-329.
    • (2003) Biol. Psychiatry , vol.54 , pp. 317-329
    • Musselman, D.L.1    Betan, E.2    Larsen, H.3    Phillips, L.S.4
  • 50
    • 0033787726 scopus 로고    scopus 로고
    • Insulin resistance in patients with depression and its changes during the clinical course of depression: Minimal model analysis
    • Okamura, F., Tashiro, A., Utumi, A., Imai, T., Suchi, T., Tamura, D., Sato, Y., Suzuki, S., Hongo, M. (2000) Insulin resistance in patients with depression and its changes during the clinical course of depression: Minimal model analysis. Metabolism 49, 1255-1260.
    • (2000) Metabolism , vol.49 , pp. 1255-1260
    • Okamura, F.1    Tashiro, A.2    Utumi, A.3    Imai, T.4    Suchi, T.5    Tamura, D.6    Sato, Y.7    Suzuki, S.8    Hongo, M.9
  • 51
    • 33846863589 scopus 로고    scopus 로고
    • Nitric oxide and peroxynitrite in health and disease
    • Pacher, P., Beckman, J. S., Liaudet, L. (2007) Nitric oxide and peroxynitrite in health and disease. Physiol. Rev. 87, 315-424.
    • (2007) Physiol. Rev , vol.87 , pp. 315-424
    • Pacher, P.1    Beckman, J.S.2    Liaudet, L.3
  • 53
    • 0026906520 scopus 로고
    • Dinucleotide repeat polymorphism at the human gene for the brain-derived neurotrophic factor (BDNF)
    • Pröschel, M., Saunders, A., Roses, A. D., Müller, C. R. (1992) Dinucleotide repeat polymorphism at the human gene for the brain-derived neurotrophic factor (BDNF). Hum. Mol. Genet. 1, 353.
    • (1992) Hum. Mol. Genet , vol.1 , pp. 353
    • Pröschel, M.1    Saunders, A.2    Roses, A.D.3    Müller, C.R.4
  • 55
    • 0037118703 scopus 로고    scopus 로고
    • Metabolic syndrome. Pathophysiology and implications for management of cardiovascular disease
    • Reaven, G. M. (2002) Metabolic syndrome. Pathophysiology and implications for management of cardiovascular disease. Circulation 106, 286-288.
    • (2002) Circulation , vol.106 , pp. 286-288
    • Reaven, G.M.1
  • 58
    • 49749101642 scopus 로고    scopus 로고
    • Serum brain-derived neurotrophic factor, depression, and antidepressant medications: Meta analyses and implications
    • Sen, S., Duman, R, Sanacora, G. (2008) Serum brain-derived neurotrophic factor, depression, and antidepressant medications: meta analyses and implications. Biol. Psychiatry 64, 527-532.
    • (2008) Biol. Psychiatry , vol.64 , pp. 527-532
    • Sen, S.1    Duman, R.2    Sanacora, G.3
  • 59
  • 60
    • 1842486891 scopus 로고    scopus 로고
    • Ethnic difference of the BDNF 196G/A (va166met) polymorphism frequencies: The possibility to explain ethnic mental traits
    • Shimizu, E., Hashimoto, K., Iyo, M. (2004) Ethnic difference of the BDNF 196G/A (va166met) polymorphism frequencies: the possibility to explain ethnic mental traits. Am. J. Med. Genet. B Neuropsychiatr. Genet. 126, 122-123.
    • (2004) Am. J. Med. Genet. B Neuropsychiatr. Genet , vol.126 , pp. 122-123
    • Shimizu, E.1    Hashimoto, K.2    Iyo, M.3
  • 62
    • 33846634095 scopus 로고    scopus 로고
    • No association between the BDNF Va166Met polymorphism and mood status in a non-clinical community sample of 7389 older adults
    • Surtees, P. G., Wainwright, N. W., Willis-Owen, S. A., Sandhu, M. S., Luben, R., Day, N. E., Flint, J. (2007) No association between the BDNF Va166Met polymorphism and mood status in a non-clinical community sample of 7389 older adults. J. Psychiatr. Res. 41, 404-409.
    • (2007) J. Psychiatr. Res , vol.41 , pp. 404-409
    • Surtees, P.G.1    Wainwright, N.W.2    Willis-Owen, S.A.3    Sandhu, M.S.4    Luben, R.5    Day, N.E.6    Flint, J.7
  • 63
    • 36949031489 scopus 로고    scopus 로고
    • Are genetic variants of the methyl group metabolism enzymes risk factors predisposing to obesity?
    • Terruzzi, L, Senesi, P., Fermo, I., Lattuada, G., Luzi, L. (2007) Are genetic variants of the methyl group metabolism enzymes risk factors predisposing to obesity? J. Endocrinol. Invest. 30, 747-753.
    • (2007) J. Endocrinol. Invest , vol.30 , pp. 747-753
    • Terruzzi, L.1    Senesi, P.2    Fermo, I.3    Lattuada, G.4    Luzi, L.5
  • 65
    • 0032964266 scopus 로고    scopus 로고
    • A systematic review of the mortality of depression
    • Wulsin, L. R, Vaillant, G. E., Wells, V. E. (1999). A systematic review of the mortality of depression. Psychosom. Med. 61, 6-17.
    • (1999) Psychosom. Med , vol.61 , pp. 6-17
    • Wulsin, L.R.1    Vaillant, G.E.2    Wells, V.E.3
  • 66
    • 3042524986 scopus 로고    scopus 로고
    • Consequences of moderate hyperhomocysteinaemia in internal medicine
    • In Czech
    • Zǎk, A., Zeman, M. (2004) Consequences of moderate hyperhomocysteinaemia in internal medicine. Cas. Lek. Cesk. 143, 367-374. (In Czech)
    • (2004) Cas. Lek. Cesk , vol.143 , pp. 367-374
    • Zǎk, A.1    Zeman, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.