Role of MT-MMPs and MMP-2 in pancreatic cancer progression

International Journal of Cancer

Volumn 85, Issue 1, 2000, Pages 14-20

  Ellenrieder, Volker ^a   Alber, Burkhard ^a   Lacher, Ulrike ^a   Hendler, Sandra F ^a   Menke, Andre ^a   Boeck, Wolfgang ^a   Wagner, Martin ^a   Wilda, Monika ^a   Friess, Helmut ^b   Büchler, Markus ^b   Adler, Guido ^a   Gress, Thomas M ^a  

^a UNIVERSITY OF ULM   (Germany)

^b UNIVERSITY OF BERN   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

GELATINASE A; MATRIX METALLOPROTEINASE;

ARTICLE; CANCER GROWTH; CANCER INVASION; CHRONIC PANCREATITIS; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; IN SITU HYBRIDIZATION; PANCREAS CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION;

ADENOCARCINOMA; DISEASE PROGRESSION; FIBROSIS; GELATIN; HUMANS; MATRIX METALLOPROTEINASE 15; MATRIX METALLOPROTEINASE 16; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MATRIX METALLOPROTEINASES; MATRIX METALLOPROTEINASES, MEMBRANE-ASSOCIATED; METALLOENDOPEPTIDASES; NEOPLASM INVASIVENESS; PANCREATIC NEOPLASMS; RNA, MESSENGER; TUMOR CELLS, CULTURED;

EID: 0033991191     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(20000101)85:1<14::AID-IJC3>3.0.CO;2-O     Document Type: Article

References (19)

1. ALBINI, A., IWAMOTO, Y., KLEINMAN, H.K., MARTIN, G.R., AARONSON, S.A., KOZLOWSKI, J.M. and MCEWAN, R.N., A rapid in vitro assay for quantitating the invasive potential of tumor cells. Cancer Res., 47, 3239-3245 (1987).
2. BRAMHALL, S.R., NEOPTOLEMOS, J.P., STAMP, G.W. and LEMOINE, N.R., Imbalance of expression of matrix metalloproteinases (MMPs) and tissue inhibitors of the matrix metalloproteinases (TIMPs) in human pancreatic carcinoma. J. Pathol., 182, 347-355 (1998).
3. BROWN, P.D., BLOXIDGE, R.E., STUART, N.S.A., GATTER, K.C. and CARMICHAEL, J., Association between expression of activated 72-kilodalton gelatinase and tumor spread in non-small-cell lung carcinoma. J. nat. Cancer Inst., 85, 574-578 (1993).
4. CAMPO, E., MERINO, M.J., TAVASSOLI, F.A., CHARONIS, A.S., STETLER-STEVENSON, W.G. and LIOTTA, L.A., Evaluation of basement membrane components and the 72 kDaA type IV collagenase in serous tumors of the ovary. Amer. J. surg. Pathol., 16, 500-507 (1992).
5. DAVIES, B., MILES, D.W., HAPPERFIELD, L.C., NAYLOR, M.S., BOBROW, L.G., RUBENS, R.D. and BALKWILL, F.R., Activity of type IV collagenases in benign and malignant breast disease. Brit. J. Cancer, 67, 1126-1131 (1993).
6. ELLENRIEDER, V., ADLER, G. and GRESS, T.M., Invasion and metastasis in pancreatic cancer. Ann. Oncol., 10 (Suppl. 4), 46-50 (1999).
7. FRIESS, H., YAMANAKI, Y., BÜCHLER, M., EBERT, M., BEGER, H.G., GOLD, L.I. and KORC, M., Enhanced expression of transforming growth factor beta isoforms in pancreatic cancer correlates with decreased survival. Gastroenterology, 105, 1846-1856 (1993).
8. GRESS, T.M., MENKE, A., BACHEM, M., MÜLLER-PILLASCH, F., ELLENRIEDER, V., WEIDENBACH, H., WAGNER, M. and ADLER, G., The role of extracellular matrix in pancreatic diseases. Digestion, 59, 625-637 (1998).
9. GRESS, T.M., MÜLLER-PILLASCH, F., LERCH, M.M., FRIESS, H., BÜCHLER, M. and ADLER, G., Expression and in situ localization of genes coding for extracellular matrix proteins and extracellular matrix degrading proteases in pancreatic cancer. Int. J. Cancer, 62, 407-413 (1995).
10. KINOSHITA, T., SATO, H., TAKINO, T., ITOH, M., AKIZAWA, T. and SEIKI M., Processing of a precursor of 72-kilodalton type IV collagenase/gelatinase A by a recombinant membrane-type 1 matrix metalloproteinase. Cancer Res 56, 2535-2538 (1996).
11. LIOTTA, L.A., STEEG, P.S. and STETLER-STEVENSON, W.G., Cancer metastasis and angiogenesis: an imbalance of positive and negative regulation. Cell, 64, 327-336 (1991).
12. NOMURA, H., SATO, H., SEIKI, M., MAI, M. and OKADA, Y., Expression of membrane-type matrix metalloproteinase in human gastric carcinomas Cancer Res., 55, 3263-3266 (1995).
13. OKADA, A., BELLOCQ, J.P., ROUYER, N., CHENARD, M.P., RIO, M.C., CHAMBON, P. and BASSET, P., Membrane-type matrix metalloproteinase (MT-MMP) gene is expressed in stromal cells of colon, breast, and head and neck carcinomas. Proc. nat. Acad. Sci. (Wash.), 92, 2730-2734 (1995).
14. OKADA, Y., MORODOMI, T., ENGHILD, J.J., SUZUKI, K., YASUI, A., NAKANISHI, I., SALVESEN, G. and NAGASE, H., Matrix metalloproteinase 2 from human rheumatoid synovial fibroblasts. Purification and activation of the precursor and enzymic properties. Europ. J. Biochem., 194, 721-730 (1990).
15. SATO, H., TAKINO, T., OKADA, Y., CAO, J., SHINAGAWA, A., YAMAMOTO, E. and SEIKI, M., A matrix metalloproteinase expressed on the surface of invasive tumor cells. Nature (Lond.), 370, 61-65 (1994).
16. SATO, H., TANAKA, M., TAKINO, T., INOUE, M. and SEIKI, M., Assignment of the human genes for membrane-type-1, -2, and -3 matrix metalloproteinases (MMP14, MMP15, and MMP16) to 14q12.2, 16q12.2-q21, and 8q21, respectively, by in situ hybridization. Genomics, 39, 412-413 (1997).
17. STONELAKE, P.S., JONES, C.E., NEOPTOLEMOS, J.P. and BAKER, P.R., Proteinase inhibitors reduce basement membrane degradation by human breast cancer cell lines. Brit. J. Cancer, 75, 951-959 (1997).
18. TAKAHARA, T., FURUI, K., YATA, Y., JIN, B., ZHANG, L.P., NAMBU, S., SATO, H., SEIKI, M. and WATANABE, A., Dual expression of matrix metalloproteinase-2 and membrane-type 1-matrix metalloproteinase in fibrotic human livers. Hepatology, 26, 1521-1529 (1997).
19. TAKINO, T., SATO, H., SHINAGAWA, A. and SEIKI, M., Identification of the second membrane-type matrix metalloproteinase (MT-MMP-2) gene from a human placenta cDNA library. J. biol. Chem., 270, 23013-23020 (1995).