Mycobacterium tuberculosis Rv1419 encodes a secreted 13 kDa lectin with immunological reactivity during human tuberculosis

European Journal of Immunology

Volumn 40, Issue 3, 2010, Pages 744-753

  Nogueira, Lucas ^a,b   Cardoso, Fernanda C ^c   Mattos, Ana M ^d   Bordignon, Juliano ^e   Figueiredo, Cláudia P ^a   Dahlstrom, Pedro ^a   Frota, Cristiane C ^f   Duarte Dos Santos, Cláudia N ^e   Chalhoub, Marcelo ^g   Cavada, Benildo S ^f   Teixeira, Henrique C ^d   Oliveira, Sérgio C ^c   Barral Netto, Manoel ^b   Báfica, André ^a  

^a FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

^b INSTITUTO OSWALDO CRUZ   (Brazil)

^c FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^d FEDERAL UNIVERSITY OF JUIZ DE FORA   (Brazil)

^e INSTITUTO CARLOS CHAGAS   (Brazil)

^f FEDERAL UNIVERSITY OF CEARÁ   (Brazil)

^g Octavio Mangabeira Hospital   (Brazil)

Author keywords

Biomarkers; Lectin; Mycobacterium tuberculosis

Indexed keywords

BACTERIAL PROTEIN; BCG VACCINE; BIOLOGICAL MARKER; CYTOKINE; GAMMA INTERFERON; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G ANTIBODY; LECTIN; MONOCLONAL ANTIBODY; SIGNAL PEPTIDE; TUBERCULOSTATIC AGENT;

AMINO ACID SEQUENCE; ANTIBODY TITER; ARTICLE; BACTERIUM CULTURE; BCG VACCINATION; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN TISSUE; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; LUNG TUBERCULOSIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PERIPHERAL BLOOD MONONUCLEAR CELL; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; TREATMENT OUTCOME; WESTERN BLOTTING;

AMINO ACID SEQUENCE; ANTIBODIES, BACTERIAL; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; BASE SEQUENCE; BLOTTING, WESTERN; HUMANS; IMMUNOGLOBULIN G; IMMUNOHISTOCHEMISTRY; LECTINS; MOLECULAR SEQUENCE DATA; MYCOBACTERIUM TUBERCULOSIS; TUBERCULOSIS, PULMONARY;

EID: 77749260598     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.200939747     Document Type: Article

References (50)

1. World Health Organization. 2006. Fact Sheet No. 104. Geneva.
2. Maartens, G. and Wilkinson, R. J., Tuberculosis. Lancet 2007. 370: 2030-2043.
3. Feng, C. G., Jankovic, D., Kullberg, M., Cheever, A., Scanga, C. A., Hieny, S., Caspar, P. et al., Maintenance of pulmonary Th1 effector function in chronic tuberculosis requires persistent IL-12 production. J. Immunol. 2005. 174: 4185-4192.
4. Maglione, P. J. and Chan, J., How B cells shape the immune response against Mycobacterium tuberculosis. Eur. J. Immunol. 2009. 39: 676-686.
5. Flynn, J. L. and Chan, J., Immunology of tuberculosis. Annu. Rev. Immunol. 2001. 19: 93-129.
6. Cooper, A. M. and Flynn, J. L., The protective immune response to Mycobacterium tuberculosis. Curr. Opin. Immunol. 1995. 7: 512-516.
7. Glatman-Freedman, A., The role of antibody-mediated immunity in defense against Mycobacterium tuberculosis: advances toward a novel vaccine strategy. Tuberculosis (Edinb.) 2006. 86: 191-197.
8. Stanley, S. A., Johndrow, J. E., Manzanillo, P. and Cox, J. S., The Type I IFN response to infection with Mycobacterium tuberculosis requires ESX-1-mediated secretion and contributes to pathogenesis. J. Immunol. 2007. 178: 3143-3152.
9. Frigui, W., Bottai, D., Majlessi, L., Monot, M., Josselin, E., Brodin, P., Garnier, T. et al., Control of M tuberculosis ESAT-6 secretion and specific T cell recognition by PhoP. PLoS Pathog. 2008. 4: e33.
10. Smith, I., Mycobacterium tuberculosis pathogenesis and molecular determinants of virulence. Clin. Microbiol. Rev. 2003. 16: 463-496.
11. Abdallah, A. M., Gey van Pittius, N. C., Champion, P. A., Cox, J., Luirink, J., Vandenbroucke-Grauls, C. M., Appelmelk, B. J. and Bitter, W., Type VII secretion - mycobacteria show the way. Nat. Rev. Microbiol. 2007. 5: 883-891.
12. Guinn, K. M., Hickey, M. J., Mathur, S. K., Zakel, K. L., Grotzke, J. E., Lewinsohn, D. M., Smith, S. and Sherman, D. R., Individual RD1-region genes are required for export of ESAT-6/CFP-10 and for virulence of Mycobacterium tuberculosis. Mol. Microbiol. 2004. 51: 359-370.
13. Malen, H., Berven, F. S., Fladmark, K. E. andWiker, H. G., Comprehensive analysis of exported proteins from Mycobacterium tuberculosis H37Rv. Proteomics 2007. 7: 1702-1718.
14. Sonnenberg, M. G. and Belisle, J. T., Definition of Mycobacterium tuberculosis culture filtrate proteins by two-dimensional polyacrylamide gel electrophoresis, N-terminal amino acid sequencing, and electrospray mass spectrometry. Infect. Immun. 1997. 65: 4515-4524.
15. Brightbill, H. D., Libraty, D. H., Krutzik, S. R., Yang, R. B., Belisle, J. T., Bleharski, J. R., Maitland, M. et al., Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors. Science 1999. 285: 732-736.
16. Pathak, S. K., Basu, S., Basu, K. K., Banerjee, A., Pathak, S., Bhattacharyya, A., Kaisho, T. et al., Direct extracellular interaction between the early secreted antigen ESAT-6 of Mycobacterium tuberculosis and TLR2 inhibits TLR signaling in macrophages. Nat. Immunol. 2007. 8: 610-618.
17. Soto, G. E. and Hultgren, S. J., Bacterial adhesins: common themes and variations in architecture and assembly. J. Bacteriol. 1999. 181: 1059-1071.
18. Coutte, L., Alonso, S., Reveneau, N.,Willery, E., Quatannens, B., Locht, C. and Jacob-Dubuisson, F., Role of adhesin release for mucosal colonization by a bacterial pathogen. J. Exp. Med. 2003. 197: 735-742.
19. Prince, A., Adhesins and receptors of Pseudomonas aeruginosa associated with infection of the respiratory tract. Microb. Pathog. 1992. 13: 251-260.
20. Pethe, K., Alonso, S., Biet, F., Delogu, G., Brennan, M. J., Locht, C. and Menozzi, F. D., The heparin-binding haemagglutinin of M tuberculosis is required for extrapulmonary dissemination. Nature 2001. 412: 190-194.
21. Singh, D. D., Chandran, D., Jeyakani, J. and Chandra, N., Scanning the genome of Mycobacterium tuberculosis to identify potential lectins. Protein Pept. Lett. 2007. 14: 683-691.
22. Masungi, C., Temmerman, S., Van Vooren, J. P., Drowart, A., Pethe, K., Menozzi, F. D., Locht, C. and Mascart, F., Differential T and B cell responses against Mycobacterium tuberculosis heparin-binding hemagglutinin adhesin in infected healthy individuals and patients with tuberculosis. J. Infect. Dis. 2002. 185: 513-520.
23. Shin, A. R., Lee, K. S., Lee, J. S., Kim, S. Y., Song, C. H., Jung, S. B., Yang, C. S. et al., Mycobacterium tuberculosis HBHA protein reacts strongly with the serum immunoglobulin M of tuberculosis patients. Clin. Vaccine Immunol. 2006. 13: 869-875.
24. Moreno, F. B., Facó , F., Ceccatto, V. M., Sampaio, A. H., Costa, A. B. S., Freitas, J. L. T., Nogueira, L. L. et al., Matching carbohydrate-binding domains in Arabidopsis thaliana genome: development of a lectin database. Online J. Bioinform. 2003. 4: 96-105.
25. Tuteja, R., Type I signal peptidase: an overview. Arch. Biochem. Biophys. 2005. 441: 107-111.
26. Hazes, B., The (QxW)3 domain: a flexible lectin scaffold. Protein Sci. 1996. 5: 1490-1501.
27. Hartley, M. R. and Lord, J. M., Cytotoxic ribosome-inactivating lectins from plants. Biochim. Biophys. Acta 2004. 1701: 1-14.
28. Rosenkrands, I., King, A., Weldingh, K., Moniatte, M., Moertz, E. and Andersen, P., Towards the proteome of Mycobacterium tuberculosis. Electrophoresis 2000. 21: 3740-3756.
29. Raghavan, S., Manzanillo, P., Chan, K., Dovey, C. and Cox, J. S., Secreted transcription factor controls Mycobacterium tuberculosis virulence. Nature 2008. 454: 717-721.
30. Andersen, P., Effective vaccination of mice against Mycobacterium tuberculosis infection with a soluble mixture of secreted mycobacterial proteins. Infect. Immun. 1994. 62: 2536-2544.
31. Hubbard, R. D., Flory, C. M. and Collins, F. M., Immunization of mice with mycobacterial culture filtrate proteins. Clin. Exp. Immunol. 1992. 87: 94-98.
32. Boesen, H., Jensen, B. N., Wilcke, T. and Andersen, P., Human T-cell responses to secreted antigen fractions of Mycobacterium tuberculosis. Infect. Immun. 1995. 63: 1491-1497.
33. Coler, R. N., Skeiky, Y. A., Vedvick, T., Bement, T., Ovendale, P., Campos-Neto, A., Alderson, M. R. and Reed, S. G., Molecular cloning and immunologic reactivity of a novel low molecular mass antigen of Mycobacterium tuberculosis. J. Immunol. 1998. 161: 2356-2364.
34. Orme, I. M., Andersen, P. and Boom, W. H., T cell response to Mycobacterium tuberculosis. J. Infect. Dis. 1993. 167: 1481-1497.
35. Orme, I. M., Induction of nonspecific acquired resistance and delayed-type hypersensitivity, but not specific acquired resistance in mice inoculated with killed mycobacterial vaccines. Infect. Immun. 1988. 56: 3310-3312.
36. Cole, S. T., Brosch, R., Parkhill, J., Garnier, T., Churcher, C., Harris, D., Gordon, S. V. et al., Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature 1998. 393: 537-544.
37. Ben Amor, Y., Shashkina, E., Johnson, S., Bifani, P. J., Kurepina, N., Kreiswirth, B., Bhattacharya, S. et al., Immunological characterization of novel secreted antigens of Mycobacterium tuberculosis. Scand. J. Immunol. 2005. 61: 139-146.
38. Menozzi, F. D., Rouse, J. H., Alavi,M., Laude-Sharp, M., Muller, J., Bischoff, R., Brennan, M. J. and Locht, C., Identification of a heparin-binding hemagglutinin present in mycobacteria. J. Exp. Med. 1996. 184: 993-1001.
39. Kinhikar, A. G., Vargas, D., Li, H., Mahaffey, S. B., Hinds, L., Belisle, J. T. and Laal, S., Mycobacterium tuberculosis malate synthase is a laminin-binding adhesin. Mol. Microbiol. 2006. 60: 999-1013.
40. Laal, S., Samanich, K. M., Sonnenberg, M. G., Zolla-Pazner, S., Phadtare, J. M. and Belisle, J. T., Human humoral responses to antigens of Mycobacterium tuberculosis: immunodominance of high-molecular-mass antigens. Clin. Diagn. Lab. Immunol. 1997. 4: 49-56.
41. Samanich, K. M., Belisle, J. T., Sonnenberg, M. G., Keen, M. A., Zolla-Pazner, S. and Laal, S., Delineation of human antibody responses to culture filtrate antigens of Mycobacterium tuberculosis. J. Infect. Dis. 1998. 178: 1534-1538.
42. Imaz, M. S. and Zerbini, E., Antibody response to culture filtrate antigens of Mycobacterium tuberculosis during and after treatment of tuberculosis patients. Int. J. Tuberc. Lung Dis. 2000. 4: 562-569.
43. Reece, S. T. and Kaufmann, S. H., Rational design of vaccines against tuberculosis directed by basic immunology. Int. J. Med. Microbiol. 2008. 298: 143-150.
44. Verma, R. K. and Jain, A., Antibodies to mycobacterial antigens for diagnosis of tuberculosis. FEMS Immunol. Med. Microbiol. 2007. 51: 453-461.
45. Gasteiger, E., Gattiker, A., Hoogland, C., Ivanyi, I., Appel, R. D. and Bairoch, A., ExPASy: The proteomics server for in-depth protein knowledge and analysis. Nucleic Acids Res. 2003. 31: 3784-3788.
46. Emanuelsson, O., Brunak, S., von Heijne, G. and Nielsen, H., Locating proteins in the cell using TargetP, SignalP and related tools. Nat. Protoc. 2007. 2: 953-971.
47. Notredame, C., Higgins, D. G. and Heringa, J., T-Coffee: A novel method for fast and accurate multiple sequence alignment. J. Mol. Biol. 2000. 302: 205-217.
48. Hirschfield, G. R., McNeil, M. and Brennan, P. J., Peptidoglycan-associated polypeptides of Mycobacterium tuberculosis. J. Bacteriol. 1990. 172: 1005-1013.
49. Lee, B. Y., Hefta, S. A. and Brennan, P. J., Characterization of the major membrane protein of virulent Mycobacterium tuberculosis. Infect. Immun. 1992. 60: 2066-2074.
50. Van Weyenbergh, J., MP, P. S., Bafica, A., Cardoso, S., Wietzerbin, J. and Barral-Netto, M., IFN-beta and TGF-beta differentially regulate IL-12 activity in human peripheral blood mononuclear cells. Immunol. Lett. 2001. 75: 117-122.