Hepatic cell transplantation. Technical and methodological aspects;Trasplante celular hepático. Aspectos técnicos y metodológicos

Cirugia Espanola

Volumn 87, Issue 3, 2010, Pages 139-147

  Pareja, Eugenia ^a   Martínez, Amparo ^a   Cortés, Miriam ^a   Bonora, Ana ^a   Moya, Ángel ^a   Sanjuán, Fernando ^a   Gómez Lechón, M José ^a   Mir, José ^a  

^a HOSPITAL UNIVERSITARIO LA FE   (Spain)

Author keywords

Cell therapy; Cryopreservation; Isolation of hepatocytes; Liver cell transplantation

Indexed keywords

ARTICLE; CELL TRANSPLANTATION; CYTOLOGY; HUMAN; LIVER; LIVER CELL; METHODOLOGY; TRANSPLANTATION;

CELL TRANSPLANTATION; HEPATOCYTES; HUMANS; LIVER;

EID: 77649339428     PISSN: 0009739X     EISSN: 1578147X     Source Type: Journal    
DOI: 10.1016/j.ciresp.2009.10.002     Document Type: Article

References (50)

1. Strom S.C., Fisher R.A., Thompson M.T., Sanyal A.J., Cole P.E., Ham J.M., et al. Hepatocyte transplantation as a bridge to orthotopic liver transplantation in terminal liver failure. Transplantation 1997, 63:559-569.
2. Smets F., Najimi M., Sokal E.M. Cell transplantation in the treatment of liver diseases. Pediatr Transplant 2008, 12:6-13.
3. Palmes D., Qayumi A.K., Spiegel H.U. Liver bridging techniques in the treatment of acute liver failure. J Invest Surg 2000, 3:299-311.
4. Riordan S.M., Williams R. Extracorporeal support and hepatocyte transplantation in acute liver failure and cirrhosis. J Gastroenterol Hepatol 1999, 14:757-770.
5. Yang Y.G., Sykes M. Xenotransplantation: Current status and a perspective on the future. Nat Rev Immunol 2007, 7:519-531.
6. Strom S.C., Fisher R.A., Rubinstein W.S., Barranger J.A., Towbin R.B., Charron M., et al. Transplantation of human hepatocytes. Transplant Proc 1997, 29:2103-2106.
7. Dhawan A., Mitry R.R., Hughes R.D. Hepatocyte transplantation for metabolic disorders, experience at King's College Hospital and review of literature. Acta Gastroenterol Belg 2005, 68:457-460.
8. Fisher R.A., Strom S.C. Human hepatocyte transplantation: Worldwide results. Transplantation 2006, 82:441-449.
9. Muraca M., Gerunda G., Neri D., Vilei M.T., Granato A., Feltracco P., et al. Hepatocyte transplantation as a treatment for glycogen storage disease type 1a. Lancet 2002, 359:317-318.
10. Bilir B.M., Guinette D., Karrer F., Kumpe D.A., Krysl J., Stephens J., et al. Hepatocyte transplantation in acute liver failure. Liver Transpl 2000, 6:32-40.
11. Habibullah C.M., Syed I.H., Qamar A., Taher-Uz Z. Human fetal hepatocyte transplantation in patients with fulminant hepatic failure. Transplantation 1994, 58:951-952.
12. Dhawan A., Mitry R.R., Hughes R.D., Lehec S., Terry C., Bansal S., et al. Hepatocyte transplantation for inherited factor VII deficiency. Transplantation 2004, 78:1812-1814.
13. Ambrosino G., Varotto S., Strom S.C., Guariso G., Franchin E., Miotto D., et al. Isolated hepatocyte transplantation for Crigler-Najjar syndrome type 1. Cell Transplant 2005, 14:151-157.
14. Navarro-Álvarez N., Soto-Gutiérrez A., Kobayashi N. Hepatocyte transplantation: A step forward. Curr Opin Organ Transplant 2007, 12:652-658.
15. Ito M., Nagata H., Miyakawa S., Fox I.J. Review of hepatocyte transplantation. J Hepatobiliary Pancreat Surg 2008, 6:34-38.
16. Alexandrova K., Griesel C., Barthold M., Heuft H.G., Ott M., Winkler M., et al. Large-scale isolation of human hepatocytes for therapeutic application. Cell Transplant 2005, 14:845-853.
17. Fox I.J., Chowdhury J.R., Kaufman S.S., Goertzen T.C., Chowdhury N.R., Warkentin P.I., et al. Treatment of the Crigler-Najjar syndrome type I with hepatocyte transplantation. N Engl J Med 1998, 338:1422-1426.
18. Mitry R.R., Hughes R.D., Dhawan A. Progress in human hepatocytes: Isolation, culture & cryopreservation. Semin Cell Dev Biol 2002, 13:463-467.
19. Mitry R.R., Dhawan A., Hughes R.D., Bansal S., Lehec S., Terry C., et al. One liver, three recipients: Segment IV from split-liver procedures as a source of hepatocytes for cell transplantation. Transplantation 2004, 77:1614-1616.
20. Gunasegaram A., Akhter J., Yao P., Johnson L.A., Riodan S.M., Morris D.L. Hepatocytes isolated from neoplastic liver-immunomagnetic purging as a new source for transplantation. World J Gastroenterol 2008, 28:5025-5031.
21. Terry C., Dhawan A., Mitry R.R., Hughes R.D. Cryopreservation of isolated human hepatocytes for transplantation: State of the art. Cryobiology 2006, 53:149-159.
22. Strom S.C., Jirtle R.L., Jones R.S., Novicki D.L., Rosenberg M.R., Novotny A, et al. Isolation, culture, and transplantation of human hepatocytes. J Natl Cancer Inst 1982, 68:771-778.
23. Gómez-Lechón M.J., Donato M.T., Ponsoda X., Fabra R., Trullenque R., Castell J.V. Isolation, culture and use of human hepatocytes in drug research. In vitro methods in pharmaceitical research 1997, Academic Press, London.
24. Donini A., Baccarini U., Piccolo G., Lavaroni S., Dialti V., Cautero N., et al. Hepatocyte isolation using human livers discarded from transplantation. Analysis of cell yield and function. Transplant Proc 2001, 33:654-655.
25. Nakazawa F, Cai H, Miki T, Dorko K, Abdelmeguid A, Walldorf J, et al. Human hepatocyte isolation from cadaver donor liver, Proccedings of Falk Symposium 126 (Progress in Gastroenterology and Hepatology Part III), Kluwer Academic Publishers (Dordrecht, Londres). 2001. p. 147-58.
26. Gómez-Lechón M.J., Donato M.T., Castell J.V. Use of cultured hepatocytes to investigate drug metabolism and toxicity. In Vitro Toxicol 1997, 10:63-70.
27. Mitry R.R., Hughes R.D., Aw M.M., Terry C., Mieli-Vergani G., Girlanda R., et al. Human hepatocyte isolation and relationship of cell viability to early graft function. Cell Transplant 2003, 12:69-74.
28. Berry M.N., Friend D.S. High-yield preparation of isolated rat liver parenchymal cells: A biochemical and fine structural study. J Cell Biol 1969, 43:506-520.
29. Donato M.T., Lahoz A., Jiménez N., Pérez G., Serralta A., Mir J., et al. Potential impact of steatosis on cytochrome P450 enzymes of human hepatocytes isolated from fatty liver grafts. Drug Metab Dispos 2006, 34:1556-1562.
30. Serralta A., Donato M.T., Orbis F., Castell J.V., Mir J., Gómez-Lechón M.J. Functionality of cultured human hepatocytes from elective samples, cadaveric grafts and hepatectomies. Toxicol In Vitro 2003, 17:769-774.
31. Donato M.T., Serralta A., Jiménez N., Pérez G., Castell J.V., Mir J., et al. Liver grafts preserved in Celsior solution as source of hepatocytes for drug metabolism studies: Comparison with surgical liver biopsies. Drug Metab Dispos 2005, 33:108-114.
32. Bonora-Centelles A., Jover R., Donato M.T., Lahoz A., Pareja E., Castell J.V., et al. Desarrollo, análisis y optimización de modelos celulares hepáticos para estudios de fármaco-toxicología y terapia celular. An R Acad Nac Farm 2008, 74:283-306.
33. Gómez-Lechón M.J., Lahoz A., Jiménez N., Bonora A., Castell J.V., Donato M.T. Evaluation of drug-metabolising and functional competence of human hepatocytes incubatedunder hypothermia in different media for clinical infusion. Cell Transplantation 2008, 17:887-897.
34. Donato M.T., Jiménez N., Castell J.V., Gómez-Lechón M.J. Fluorescence-based assays for screening nine cytochrome P450 (P450) activities in intact cells expressing individual human P450 enzymes. Drug Metab Dispos 2004, 32:699-706.
35. Dhawan A., Mitry R.R., Hughes R.D. Hepatocyte transplantation for liver-based metabolic disorders. J Inherit Metab Dis 2006, 29:431-435.
36. Donato M.T., Viitala P., Rodríguez-Antona C., Lindfors A., Castell J.V., Raunio H., et al. CYP2A5/CYP2A6 expression in mouse and human hepatocytes treated with various in vivo inducers. Drug Metab Dispos 2000, 28:1321-1326.
37. Rodríguez-Antona C., Jover R., Gómez-Lechón M.J., Castell J.V. Quantitative RT-PCR measurement of human cytochrome P-450s: Application to drug induction studies. Arch Biochem Biophys 2000, 376:109-116.
38. Donato M.T., Lahoz A., Montero S., Bonora A., Pareja E., Mir J., et al. A functional assessment of the quality of human hepatocyte preparations for cell transplantation. Cell Transplantation 2008, 17:1211-1219.
39. Selden C., Hodgson H. Cellular therapies for liver replacement. Transpl Immunol 2004, 12:273-288.
40. Stepehenne X., Najimi M., Smets F., Reding R., De Ville de Goyet J., Sokal E.M. Cryopreserved liver cell transplantation controls ornithine transcarbamylase deficient patient while awaiting liver transplantation. Am J Transplant 2005, 5:2058-2061.
41. Sokal E.M. Liver transplantation for inborn errors of liver metabolism. J Inherit Metab Dis 2006, 29:426-430.
42. Horslen S.P., McCowan T.C., Goertzen T.C., Warkentin P.I., Cai H.B., Strom S.C., et al. Isolated hepatocyte transplantation in an infant with a severe urea cycle disorder. Pediatrics 2003, 111:1262-1267.
43. Darwish A.A., Sokal E., Stephenne X., Najimi M., De Ville de Goyet J., Reding R. Permanent access to the portal system for cellular transplantation using an implantable port device. Liver Transpl 2004, 10:1213-1215.
44. Baccarini U., Adani G.L., Sanna A., Avellini C., Sainz-Barriga M., Lorenzin D., et al. Portal vein trombosis after intraportal hepatocytes transplantation in a liver transplant recipient. Transpl Int 2005, 18:750-754.
45. Strom S.C., Roy-Chowdhury J., Fox I.J. Hepatocyte transplantation for the treatment of human disease. Sem Liver Dis 1999, 9:39-48.
46. Nagata Route of hepatocyte delivery affects hepatocyte engraftment in the spleen. Transplantation 2003, 76:732-734.
47. Gómez-Lechón M.J., Serralta A., Donato M.T., Jiménez N., O'Connorc E., Castell J.V., et al. The immunosuppressant drug FK506 prevents Fas-induced apoptosis in human hepatocytes. Biochem Pharmacol 2004, 68:2427-2433.
48. Zvibel I., Smets F., Soriano H. Anoikis: Roadblock to cell transplantation?. Cell Transplant 2002, 11:621-630.
49. Fisher R A., Bu D., Thompson M., Wolfe L., Ritter J K. Optimization of conditions for clinical human hepatocyte infusion. Cell Transplant 2004, 13:677-689.
50. Terry C., Hughes R.D., Mitry R R., Lehec S C., Dhawan A. Cryopreservation-induced nonattachment of human hepatocytes: Role of adhesion molecules. Cell Transplant 2007, 16:639-647.