-
1
-
-
0021126053
-
Prolonged maintenance of active cytochrome P450 in adult rat hepatocytes co-cultured with another liver cell type
-
BEGUE, J., GUGUEN-GUILLOUZO, C., PASDELOUP, N., and GUILLOUZO, A. (1984). Prolonged maintenance of active cytochrome P450 in adult rat hepatocytes co-cultured with another liver cell type. Hepatology 4, 839-842.
-
(1984)
Hepatology
, vol.4
, pp. 839-842
-
-
Begue, J.1
Guguen-Guillouzo, C.2
Pasdeloup, N.3
Guillouzo, A.4
-
2
-
-
0344363469
-
The in vitro evaluation of the potential risk of hepatotoxicity of drugs
-
J.V. Castell and M.J. Gómez-Lechón (eds.) Farmaindustria: Madrid
-
CASTELL, J.V., and GOMEZ-LECHON, M.J. (1992). The in vitro evaluation of the potential risk of hepatotoxicity of drugs, in: In Vitro Alternatives to Animal Pharmacotoxicology. J.V. Castell and M.J. Gómez-Lechón (eds.) Farmaindustria: Madrid, pp. 179-204.
-
(1992)
In Vitro Alternatives to Animal Pharmacotoxicology
, pp. 179-204
-
-
Castell, J.V.1
Gomez-Lechon, M.J.2
-
3
-
-
0028783267
-
Relationship between in vitro and in vivo biotransformation of drugs in humans and animals: Pharma-toxicological consequences
-
DE SOUSA, G., FLORENCE, N., VALLES, B., COASSOLO, P., and RAHAMANI, R. (1995). Relationship between in vitro and in vivo biotransformation of drugs in humans and animals: pharma-toxicological consequences. Cell. Biol. Toxicol. 11, 147-153.
-
(1995)
Cell. Biol. Toxicol.
, vol.11
, pp. 147-153
-
-
De Sousa, G.1
Florence, N.2
Valles, B.3
Coassolo, P.4
Rahamani, R.5
-
4
-
-
0025605025
-
Drug metabolizing enzymes in rat hepatocytes co-cultured with cell lines
-
DONATO, M.T., GOMEZ-LECHON, M.J., and CASTELL, J.V. (1990). Drug metabolizing enzymes in rat hepatocytes co-cultured with cell lines. In Vitro Cell Dev. Biol. 26, 1057-1062.
-
(1990)
In Vitro Cell Dev. Biol.
, vol.26
, pp. 1057-1062
-
-
Donato, M.T.1
Gomez-Lechon, M.J.2
Castell, J.V.3
-
5
-
-
0000697342
-
Biotransformation of drugs by cultured hepatocytes
-
J.V. Castell and M.J. Gómez-Lechón (eds.) Farmaindustria: Madrid
-
DONATO, M.T., CASTELL, J.V., and GOMEZ-LECHON, M.J. (1992). Biotransformation of drugs by cultured hepatocytes, in: In Vitro Alternatives to Animal Pharmaco-toxicology. J.V. Castell and M.J. Gómez-Lechón (eds.) Farmaindustria: Madrid, pp. 149-178.
-
(1992)
In Vitro Alternatives to Animal Pharmaco-toxicology
, pp. 149-178
-
-
Donato, M.T.1
Castell, J.V.2
Gomez-Lechon, M.J.3
-
6
-
-
0028120329
-
Evaluation of the xenobiotic biotransformation capability of six rodent hepatoma cell lines in comparison with rat hepatocytes
-
DONATO, M.T., BASSI, A.M., GOMEZ-LECHON, M.J., PENCO, S., HERRERO, E., ADAMO, D., CASTELL, J.V., et al. (1994a). Evaluation of the xenobiotic biotransformation capability of six rodent hepatoma cell lines in comparison with rat hepatocytes. In Vitro Cell. Dev. Biol 30A, 574-580.
-
(1994)
In Vitro Cell. Dev. Biol
, vol.30 A
, pp. 574-580
-
-
Donato, M.T.1
Bassi, A.M.2
Gomez-Lechon, M.J.3
Penco, S.4
Herrero, E.5
Adamo, D.6
Castell, J.V.7
-
7
-
-
0028586738
-
Cytochrome P450 activities in pure and co-cultured rat hepatocytes. Effect of model inducers
-
DONATO, M.T., CASTELL, J.V., and GOMEZ-LECHON, M.J. (1994b). Cytochrome P450 activities in pure and co-cultured rat hepatocytes. Effect of model inducers. In Vitro Cell. Dev. Biol. 30A, 825-832.
-
(1994)
In Vitro Cell. Dev. Biol.
, vol.30 A
, pp. 825-832
-
-
Donato, M.T.1
Castell, J.V.2
Gomez-Lechon, M.J.3
-
8
-
-
0029033092
-
Effect of model inducers on cytochrome P450 activities of human hepatocytes in primary cultures
-
DONATO, M.T., CASTELL, J.V., and GOMEZ-LECHON, M.J. (1995). Effect of model inducers on cytochrome P450 activities of human hepatocytes in primary cultures. Drug Metab. Dispos. 23, 553-558.
-
(1995)
Drug Metab. Dispos.
, vol.23
, pp. 553-558
-
-
Donato, M.T.1
Castell, J.V.2
Gomez-Lechon, M.J.3
-
9
-
-
0026547439
-
Hepatocytes in collagen sandwich: Evidence for transcriptional and translational regulation
-
DUNN, J.C.Y., TOMPKINS, R.G., and YARMUSH, M.L. (1992). Hepatocytes in collagen sandwich: Evidence for transcriptional and translational regulation. J. Cell Biol. 116, 1043-1053.
-
(1992)
J. Cell Biol.
, vol.116
, pp. 1043-1053
-
-
Dunn, J.C.Y.1
Tompkins, R.G.2
Yarmush, M.L.3
-
10
-
-
0342474025
-
Predictive value of the in vitro tests for hepatotoxicity of xenobiotics
-
A. Guillouzo (ed.) Colloque INSERM, John Libbey Eurotext: Paris
-
GOMEZ-LECHON, M.J., LARRAURI, A., DONATO, T., LOPEZ, P., MONTOYA, A., and CASTELL, J.V. (1988). Predictive value of the in vitro tests for hepatotoxicity of xenobiotics, in: Liver Cells and Drugs. A. Guillouzo (ed.) Colloque INSERM, John Libbey Eurotext: Paris, vol 164, pp. 371-377.
-
(1988)
Liver Cells and Drugs
, vol.164
, pp. 371-377
-
-
Gomez-Lechon, M.J.1
Larrauri, A.2
Donato, T.3
Lopez, P.4
Montoya, A.5
Castell, J.V.6
-
11
-
-
0025037764
-
Culture of human hepatocytes from small surgical liver biopsies. Biochemical characterization and comparison with in vivo
-
GOMEZ-LECHON, M.J., LOPEZ, P., DONATO, T., MONTOYA, A., LARRAURI, A., GIMENEZ, P., TRULLENQUE, R., et al. (1990). Culture of human hepatocytes from small surgical liver biopsies. Biochemical characterization and comparison with in vivo. In Vitro Cell. Dev. Biol. 26, 67-74.
-
(1990)
In Vitro Cell. Dev. Biol.
, vol.26
, pp. 67-74
-
-
Gomez-Lechon, M.J.1
Lopez, P.2
Donato, T.3
Montoya, A.4
Larrauri, A.5
Gimenez, P.6
Trullenque, R.7
-
12
-
-
0023197883
-
Human adult hepatocytes in primary monolayer cultures. Maintenance of mixed function oxidase and conjugation pathways of drug metabolism
-
GRANT, M.H., BURKE, M.D., HAWKSWORTH, G.M., DUTHIE, S.J., ENGESET, J., and PETRIE, J.C. (1987). Human adult hepatocytes in primary monolayer cultures. Maintenance of mixed function oxidase and conjugation pathways of drug metabolism. Biochem. Pharmacol. 36, 2311-2816.
-
(1987)
Biochem. Pharmacol.
, vol.36
, pp. 2311-2816
-
-
Grant, M.H.1
Burke, M.D.2
Hawksworth, G.M.3
Duthie, S.J.4
Engeset, J.5
Petrie, J.C.6
-
13
-
-
0027489375
-
Use of human hepatocyte cultures for drug metabolism studies
-
GUILLOUZO, A., MOREL, F., FARDEL, O., and MEUNIER, B. (1993). Use of human hepatocyte cultures for drug metabolism studies. Toxicology 82, 209-219.
-
(1993)
Toxicology
, vol.82
, pp. 209-219
-
-
Guillouzo, A.1
Morel, F.2
Fardel, O.3
Meunier, B.4
-
14
-
-
0027932864
-
Expression of xenobioticmetabolizing cytochrome P450 forms in human adult and fetal liver
-
HAKKOLA, J., PASANEN, M., PURKUNEN, R., SAARIKOSKI, S., PELKONEN, O., MAENPA, J., RANE, A., et al. (1994). Expression of xenobioticmetabolizing cytochrome P450 forms in human adult and fetal liver. Biochem. Pharmacol. 48, 59-64.
-
(1994)
Biochem. Pharmacol.
, vol.48
, pp. 59-64
-
-
Hakkola, J.1
Pasanen, M.2
Purkunen, R.3
Saarikoski, S.4
Pelkonen, O.5
Maenpa, J.6
Rane, A.7
-
15
-
-
0028209259
-
Collagen gel immobilization: A useful cell culture technique for long-term metabolic studies on human hepatocytes
-
KOEBE, H.G., PATHERNIK, S., EYER, P., and SCHILDBERG, F.W. (1994). Collagen gel immobilization: A useful cell culture technique for long-term metabolic studies on human hepatocytes. Xenobiotica 24, 95-107.
-
(1994)
Xenobiotica
, vol.24
, pp. 95-107
-
-
Koebe, H.G.1
Pathernik, S.2
Eyer, P.3
Schildberg, F.W.4
-
16
-
-
0002252722
-
Physiologically based pharmacokinetic modeling in toxicology
-
A.W. Hayes (ed.) Raven Press: New York
-
KRISHNAN, K., and ANDERSEN, M.E. (1994). Physiologically based pharmacokinetic modeling in toxicology, in: Principles and Methods of Toxicology. A.W. Hayes (ed.) Raven Press: New York, pp. 149-188.
-
(1994)
Principles and Methods of Toxicology
, pp. 149-188
-
-
Krishnan, K.1
Andersen, M.E.2
-
17
-
-
0022472879
-
Induction of drug-metabolizing enzymes: Mechanisms and consequences
-
OKEY, A.B., ROBERTS, E.A., HARPER, P.A., and DENISON, M.S. (1986). Induction of drug-metabolizing enzymes: Mechanisms and consequences. Clin. Biochem. 19, 132-141.
-
(1986)
Clin. Biochem.
, vol.19
, pp. 132-141
-
-
Okey, A.B.1
Roberts, E.A.2
Harper, P.A.3
Denison, M.S.4
-
18
-
-
0026590009
-
Potentiation of cocaine hepatotoxicity in human hepatocytes by ethanol
-
PONSODA, X., JOVER, R., CASTELL, J.V., and GOMEZ-LECHON, M.J. (1992). Potentiation of cocaine hepatotoxicity in human hepatocytes by ethanol. Toxicol. In Vitro 6, 155-158.
-
(1992)
Toxicol. In Vitro
, vol.6
, pp. 155-158
-
-
Ponsoda, X.1
Jover, R.2
Castell, J.V.3
Gomez-Lechon, M.J.4
-
19
-
-
0029033229
-
Molecular mechanisms of diclofenac hepatotoxicity: Cell injury is associated to the metabolism of the drug and is preluded by a decrease in ATP levels
-
PONSODA, X., BORT, R., JOVER, R., GOMEZ-LECHON, M.J., and CASTELL, J.V. (1995). Molecular mechanisms of diclofenac hepatotoxicity: Cell injury is associated to the metabolism of the drug and is preluded by a decrease in ATP levels. Toxicol. In Vitro 9, 439-444.
-
(1995)
Toxicol. In Vitro
, vol.9
, pp. 439-444
-
-
Ponsoda, X.1
Bort, R.2
Jover, R.3
Gomez-Lechon, M.J.4
Castell, J.V.5
-
20
-
-
0028347408
-
Metabolism of three pharmacologically active drugs in isolated human and rat hepatocytes: Analysis of interspecies variability and comparison with metabolism in vivo
-
SANDKER, G.W., VOS, R.M., DELBRESSINE, L.P., SLOOFF, M.J., MEIJER, D.K., and GROOTHIS, G.M. (1994). Metabolism of three pharmacologically active drugs in isolated human and rat hepatocytes: Analysis of interspecies variability and comparison with metabolism in vivo. Xenobiotica 24, 143-155.
-
(1994)
Xenobiotica
, vol.24
, pp. 143-155
-
-
Sandker, G.W.1
Vos, R.M.2
Delbressine, L.P.3
Slooff, M.J.4
Meijer, D.K.5
Groothis, G.M.6
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