-
1
-
-
0034791598
-
The spectrum of liver disease in the general population: Lesson from the Dionysos study
-
BELLENTANI, S. y TRIBELLI, C. (2001): The spectrum of liver disease in the general population: lesson from the Dionysos study. Physiol. Rev. 35: 531-537.
-
(2001)
Physiol. Rev
, vol.35
, pp. 531-537
-
-
BELLENTANI, S.1
TRIBELLI, C.2
-
2
-
-
33747871550
-
Human hepatocyte transplantation: Worldwide results
-
FISHER, R. A. y STROM, S. C. (2006): Human hepatocyte transplantation: worldwide results. Transplantation. 82: 441-449.
-
(2006)
Transplantation
, vol.82
, pp. 441-449
-
-
FISHER, R.A.1
STROM, S.C.2
-
3
-
-
0038282311
-
The role of absorption, distribution, metabolism, secretion and toxicity in drug discovery
-
LIN, J.; SAHAKIAN, D. C.; DE MORAIS, S. M.; XU, J. J.; POLZER, R. J. y WINTER, S. M. (2003): The role of absorption, distribution, metabolism, secretion and toxicity in drug discovery. Curr. Top. Med. Chem. 3: 1125-1154.
-
(2003)
Curr. Top. Med. Chem
, vol.3
, pp. 1125-1154
-
-
LIN, J.1
SAHAKIAN, D.C.2
DE MORAIS, S.M.3
XU, J.J.4
POLZER, R.J.5
WINTER, S.M.6
-
4
-
-
0002195237
-
Isolation, culture and use of human hepatocytes in drug research
-
Academic Press, London, pp
-
GÓMEZ-LECHÓN, M. J.; DONATO, T.; PONSODA, X.; FABRA, R.; TRULLENQUE, R. y CASTELL, J. V. (1997): Isolation, culture and use of human hepatocytes in drug research. In Vitro Methods in Pharmaceutical Research. Academic Press, London, pp. 129-153.
-
(1997)
Vitro Methods in Pharmaceutical Research
, pp. 129-153
-
-
GÓMEZ-LECHÓN, M.J.1
DONATO, T.2
PONSODA, X.3
FABRA, R.4
TRULLENQUE, R.5
CASTELL, J.V.6
-
5
-
-
33750103346
-
-
Phillips GO, eds. World Scientific Publishing Co. Pte. Ltd
-
MIRABET, V.; VACA, P.; CARBONELL-U BEROS, F.; MONTERO, J. A.; DALMAU, M. J.; HORNERO, F.; LEQUERICA, J. L. y PIQUER, S. (2002): Ischaemic Herat disease: searching for therapeutical solutions. In: Phillips GO, eds. World Scientific Publishing Co. Pte. Ltd., 359-374.
-
(2002)
Ischaemic Herat disease: Searching for therapeutical solutions
, pp. 359-374
-
-
MIRABET, V.1
VACA, P.2
CARBONELL-U3
BEROS, F.4
MONTERO, J.A.5
DALMAU, M.J.6
HORNERO, F.7
LEQUERICA, J.L.8
PIQUER, S.9
-
6
-
-
33747834018
-
Potential impact of steatosis on cytochrome P450 enzymes of human hepatocytes isolated from fatty liver grafts
-
DONATO, M. T.; LAHOZ, A.; JIMÉNEZ, N.; PEREZ, G.; SERRALTA, A.; MIR, J.; CASTELL, J. V. y GÓMEZ-LECHÓN, M. J. (2006): Potential impact of steatosis on cytochrome P450 enzymes of human hepatocytes isolated from fatty liver grafts. Drug metabolism and Dispositions. 34: 1556-1562.
-
(2006)
Drug metabolism and Dispositions
, vol.34
, pp. 1556-1562
-
-
DONATO, M.T.1
LAHOZ, A.2
JIMÉNEZ, N.3
PEREZ, G.4
SERRALTA, A.5
MIR, J.6
CASTELL, J.V.7
GÓMEZ-LECHÓN, M.J.8
-
7
-
-
71849104860
-
Protein measurement with the Follin phenol reagent
-
LOWRY, O. H.; ROSEBROUGH, N. J.; FARR, A. I. y RANDALL, R. J. (1951): Protein measurement with the Follin phenol reagent. J. Biol. Chem. 193: 265-275.
-
(1951)
J. Biol. Chem
, vol.193
, pp. 265-275
-
-
LOWRY, O.H.1
ROSEBROUGH, N.J.2
FARR, A.I.3
RANDALL, R.J.4
-
8
-
-
0035083477
-
Expression and induction of a large set of drug metabolism enzymes by the highly differentiated human hematoma cell line BC2
-
GÓMEZ-LECHÓN, M. J.; DONATO, T.; JOVER, R.; RODRÍGUEZ, C.; PONSODA, X.; CLAISE, D.; CASTELL, J. V. y GUGUEN-G UILLOUZO, C. (2001): Expression and induction of a large set of drug metabolism enzymes by the highly differentiated human hematoma cell line BC2. Eur. J. Biochem. 268: 1448-1459.
-
(2001)
Eur. J. Biochem
, vol.268
, pp. 1448-1459
-
-
GÓMEZ-LECHÓN, M.J.1
DONATO, T.2
JOVER, R.3
RODRÍGUEZ, C.4
PONSODA, X.5
CLAISE, D.6
CASTELL, J.V.7
GUGUEN-G8
UILLOUZO, C.9
-
9
-
-
35649018168
-
Determination of major human cytochrome P450s activities in 96-well plates using liquid chromatography tandem mass spectrometry
-
in press
-
LAHOZ, A.; DONATO, M. T.; PICAZO, L.; GÓMEZ-LECHÓN, M. J. y CASTELL, J. V. (2007): Determination of major human cytochrome P450s activities in 96-well plates using liquid chromatography tandem mass spectrometry. Toxicol In Vitro (in press).
-
(2007)
Toxicol In Vitro
-
-
LAHOZ, A.1
DONATO, M.T.2
PICAZO, L.3
GÓMEZ-LECHÓN, M.J.4
CASTELL, J.V.5
-
10
-
-
0345017786
-
Transcription factors in liver development, differentiation, and regeneration
-
COSTA, R. H.; KALINICHENKO, V. V.; HOLTERMAN, A. X. y WANG, X. (2003): Transcription factors in liver development, differentiation, and regeneration. Hepatology. 38: 1331-1347.
-
(2003)
Hepatology
, vol.38
, pp. 1331-1347
-
-
COSTA, R.H.1
KALINICHENKO, V.V.2
HOLTERMAN, A.X.3
WANG, X.4
-
11
-
-
33846864449
-
CYP3A4 regulation and expression in hepatocytes
-
MARTÍNEZ-JIMÉNEZ, C. P.; JOVER, R.; DONATO, T.; CASTELL, J. V y GÓMEZ- LECHÓN, M. J. (2007): CYP3A4 regulation and expression in hepatocytes. Curr. Drug. Metab. 8: 185-195.
-
(2007)
Curr. Drug. Metab
, vol.8
, pp. 185-195
-
-
MARTÍNEZ-JIMÉNEZ, C.P.1
JOVER, R.2
DONATO, T.3
CASTELL, J.V.4
GÓMEZ- LECHÓN, M.J.5
-
12
-
-
33747834018
-
Potential impact of steatosis on cytochrome P450 enzymes of human hepatocytes isolated from fatty liver grafts
-
DONATO, M. T.; LAHOZ, A.; JIMÉNEZ, N.; PÉREZ, G.; SERRALTA, A.; MIR, J.; CASTELL, J. V. y GÓMEZ-LECHÓN, M. J. (2006): Potential impact of steatosis on cytochrome P450 enzymes of human hepatocytes isolated from fatty liver grafts. Drug metabolism and Dispositions. 34: 1556-1562.
-
(2006)
Drug metabolism and Dispositions
, vol.34
, pp. 1556-1562
-
-
DONATO, M.T.1
LAHOZ, A.2
JIMÉNEZ, N.3
PÉREZ, G.4
SERRALTA, A.5
MIR, J.6
CASTELL, J.V.7
GÓMEZ-LECHÓN, M.J.8
-
13
-
-
4644341747
-
Human hepatocytes in primary culture: The choice to investigate drug metabolism in man
-
GÓMEZ-LECHÓN, M. J.; DONATO, T.; CASTELL, J. V. y JOVER, R. (2004): Human hepatocytes in primary culture: the choice to investigate drug metabolism in man. Current Drug. Metab. 5: 443-462.
-
(2004)
Current Drug. Metab
, vol.5
, pp. 443-462
-
-
GÓMEZ-LECHÓN, M.J.1
DONATO, T.2
CASTELL, J.V.3
JOVER, R.4
-
14
-
-
0032582677
-
Biological role of the CCAAT/enhancer-binding protein family of transcription factors
-
LEKSTROM-HIMES, J. y XANTHOPOULOS, K. G. (1998): Biological role of the CCAAT/enhancer-binding protein family of transcription factors. J. Biol. Chem. 273: 28545-28548.
-
(1998)
J. Biol. Chem
, vol.273
, pp. 28545-28548
-
-
LEKSTROM-HIMES, J.1
XANTHOPOULOS, K.G.2
-
15
-
-
0034090310
-
Mammalian hepatocyte differentiation requires the transcription factor HNF-4alpha
-
LI, J.; NING, G. y DUNCAN, S. A. (2000): Mammalian hepatocyte differentiation requires the transcription factor HNF-4alpha. Genes Dev. 14: 464-474.
-
(2000)
Genes Dev
, vol.14
, pp. 464-474
-
-
LI, J.1
NING, G.2
DUNCAN, S.A.3
-
16
-
-
84888702510
-
-
JOVER, R. (2004): Control génico de la expresión del citocromo P-450 en el hígado. En: Citocromo P-450 (Cascales-Angosto, M. y Gómez-Lechón, M. J., Eds.), pp. 205-239. Realigraf, S. A. Press, Madrid, Spain.
-
JOVER, R. (2004): Control génico de la expresión del citocromo P-450 en el hígado. En: Citocromo P-450 (Cascales-Angosto, M. y Gómez-Lechón, M. J., Eds.), pp. 205-239. Realigraf, S. A. Press, Madrid, Spain.
-
-
-
-
17
-
-
10744231826
-
-
GEBHARDT, R.; HENGSTLER, J. G.; MULLER, D.; GLOCKNER, R.; BUENNING, P.; LAUBE, B.; SCHMELZER, E.; ULLRICH, M.; UTESCH, D.; HEWITT, N.; RINGEL, M.; HILZ, B. R.; BADER, A.; LANGSCH, A.; KOOSE, T.; BURGER, H. J.; MAAS, J. y OESCH, F. (2003): New hepatocyte in vitro systems for drug metabolism: metabolic capacity and recommendations for application in basic research and drug development, standard operation procedures. Drug Metab. Rev. 35: 145-213.
-
GEBHARDT, R.; HENGSTLER, J. G.; MULLER, D.; GLOCKNER, R.; BUENNING, P.; LAUBE, B.; SCHMELZER, E.; ULLRICH, M.; UTESCH, D.; HEWITT, N.; RINGEL, M.; HILZ, B. R.; BADER, A.; LANGSCH, A.; KOOSE, T.; BURGER, H. J.; MAAS, J. y OESCH, F. (2003): New hepatocyte in vitro systems for drug metabolism: metabolic capacity and recommendations for application in basic research and drug development, standard operation procedures. Drug Metab. Rev. 35: 145-213.
-
-
-
-
18
-
-
34547461813
-
Adipose Tissue-derived mesenchymal stem cells as a source of human hepatocytes
-
BANAS, A.; TERATANI, T.; YAMAMOTO, Y.; TOKUHARA, M.; TAKESHITA, F.; QUINN, G.; OKOCHI, H. y OCHIYA, T. (2007): Adipose Tissue-derived mesenchymal stem cells as a source of human hepatocytes. Hepatology. 46: 219-228.
-
(2007)
Hepatology
, vol.46
, pp. 219-228
-
-
BANAS, A.1
TERATANI, T.2
YAMAMOTO, Y.3
TOKUHARA, M.4
TAKESHITA, F.5
QUINN, G.6
OKOCHI, H.7
OCHIYA, T.8
-
19
-
-
12844269935
-
Differentiation of human adipose stromal cells into hepatic lineage in vitro and in vivo
-
SEO, M. J.; SUH, S. Y.; BAE, Y. C. y JUNG, J. S. (2005): Differentiation of human adipose stromal cells into hepatic lineage in vitro and in vivo. BBRC. 328: 258-264.
-
(2005)
BBRC
, vol.328
, pp. 258-264
-
-
SEO, M.J.1
SUH, S.Y.2
BAE, Y.C.3
JUNG, J.S.4
-
20
-
-
0036106054
-
Multipotent adult progenitor cells from bone marrow differentiate into functional hepatocyte-like cells
-
SCHWARTZ, R. E.; REYES, M.; KOODIE, L.; JIANG, Y.; BLACKSTAD, M. and LUND, T. (2002): Multipotent adult progenitor cells from bone marrow differentiate into functional hepatocyte-like cells. J. Clin. Invest. 109: 1291-1302.
-
(2002)
J. Clin. Invest
, vol.109
, pp. 1291-1302
-
-
SCHWARTZ, R.E.1
REYES, M.2
KOODIE, L.3
JIANG, Y.4
BLACKSTAD, M.5
LUND, T.6
-
21
-
-
0033580985
-
Initiation of mammalian liver development from endoderm by fibroblast growth factors
-
JUNG, J.; ZHENG, M.; GOLDFARB, M. and ZARET, K. S. (1999): Initiation of mammalian liver development from endoderm by fibroblast growth factors. Science. 284: 1998-2003.
-
(1999)
Science
, vol.284
, pp. 1998-2003
-
-
JUNG, J.1
ZHENG, M.2
GOLDFARB, M.3
ZARET, K.S.4
-
22
-
-
0035423751
-
Distinct mesodermal signals, including BMPs from the septum transversum mesenchyme, are required in combination for hepatogenesis from the endoderm
-
ROSSI, J. M.; DUNN, N. R.; HOGAN, L. M. and ZARET, K. S. (2001): Distinct mesodermal signals, including BMPs from the septum transversum mesenchyme, are required in combination for hepatogenesis from the endoderm. Genes & Development. 15: 1998-2009.
-
(2001)
Genes & Development
, vol.15
, pp. 1998-2009
-
-
ROSSI, J.M.1
DUNN, N.R.2
HOGAN, L.M.3
ZARET, K.S.4
-
23
-
-
0029051386
-
Effects of hepatocyte growth factor on the growth and metabolism of human hepatocytes in primary culture
-
GÓMEZ-LECHÓN, M. J.; CASTELL, J.; GUILLEN, I.; O'CONNOR, E.; NAKAMURA, T.; FABRA, R. and TRULLENQUE, R. (1995): Effects of hepatocyte growth factor on the growth and metabolism of human hepatocytes in primary culture. Hepatology. 21: 1248-1254.
-
(1995)
Hepatology
, vol.21
, pp. 1248-1254
-
-
GÓMEZ-LECHÓN, M.J.1
CASTELL, J.2
GUILLEN, I.3
O'CONNOR, E.4
NAKAMURA, T.5
FABRA, R.6
TRULLENQUE, R.7
-
24
-
-
0034119770
-
Role of oncostatin M in hematopoyesis and liver development
-
MIYAJIMA, A.; KINOSHITA, T.; TANAKA, M.; KAMIYA, A.; MUKOUYAMA, Y. and HARA, T. (2000): Role of oncostatin M in hematopoyesis and liver development. Cytokines & Growth Factors Reviews. 11: 177-183.
-
(2000)
Cytokines & Growth Factors Reviews
, vol.11
, pp. 177-183
-
-
MIYAJIMA, A.1
KINOSHITA, T.2
TANAKA, M.3
KAMIYA, A.4
MUKOUYAMA, Y.5
HARA, T.6
-
25
-
-
0026525255
-
Cell surface antigens on human marrow-derived mesenchymal cells are detected by monoclonal antibodies
-
HAYNESWORTH, S. E.; BABER, M. A. y CAPLAN, A. I. (1992): Cell surface antigens on human marrow-derived mesenchymal cells are detected by monoclonal antibodies. Bone. 13: 69-80.
-
(1992)
Bone
, vol.13
, pp. 69-80
-
-
HAYNESWORTH, S.E.1
BABER, M.A.2
CAPLAN, A.I.3
|