Identification of a new analogue of sildenafil added illegally to a functional food marketed for penile erectile dysfunction

Food Additives and Contaminants

Volumn 20, Issue 9, 2003, Pages 793-796

  Shin, M H ^a   Hong, M K ^a   Kim, W S ^a   Lee, Y J ^a   Jeoung, Y C ^a  

^a Korea Food and Drug Administration   (South Korea)

Author keywords

Erectile dysfunction; Homosildenafil; HPLC; NMR; Sildenafil

Indexed keywords

CARBENE; FOOD ADDITIVE; HOMOSILDENAFIL; PHOSPHODIESTERASE INHIBITOR; SILDENAFIL; UNCLASSIFIED DRUG; VARDENAFIL;

ANALYTIC METHOD; ARTICLE; CONTROLLED STUDY; DRUG STRUCTURE; ERECTILE DYSFUNCTION; FOOD COMPOSITION; FOOD CONTROL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LEGAL ASPECT; MARKETING; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FOOD ANALYSIS; FOOD CONTAMINATION; FOOD, FORTIFIED; HUMANS; IMPOTENCE; MALE; PHOSPHODIESTERASE INHIBITORS; PIPERAZINES; VASODILATOR AGENTS;

EID: 0142030118     PISSN: 0265203X     EISSN: None     Source Type: Journal    
DOI: 10.1080/0265203031000121455     Document Type: Article

References (4)

1. Boolell, M., Allen, M. J., Ballard, S. A., Gepi-Attee, S., Muirhead, G. J., Naylor, A. M., Osterloh, I. H., and Gingell, C., 1996, Sildenafil: an orally active type 5 cyclic GMP-specific phosphodiesterase inhibitor for the treatment of penile erectile dysfunction. International Journal of Impotence Research, 8, 47-52.
2. Dega-Szafran, Z., Jakolski, M., Kurzyca, I., Barczynski, P., and Szafran, M., 2002, Molecular structure, hydrogen bonding, basicity and spectroscopic properties of N,N′-dimethylpiperazine betaines and their hydrohalides. Journal of Molecular Structure, 614, 23-32.
3. Food Sanitation (Republic of Korea), 2000, article 2,6.
4. Ormrod, D., Easthope, S. E., and Figgitt, D. P., 2002, Vardenafil. Drug Aging, 19, 217-227.