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Volumn 5, Issue 1, 2010, Pages 73-86

In vivo neural stem cell imaging: Current modalities and future directions

Author keywords

Bioluminescence; Cell labeling; In vivo imaging; Magnetic resonance; MRI; Neural stem cells; Optical imaging; PET; Positron emission tomography; Quantum dots

Indexed keywords

QUANTUM DOT;

EID: 77649333547     PISSN: 17460751     EISSN: None     Source Type: Journal    
DOI: 10.2217/rme.09.79     Document Type: Review
Times cited : (35)

References (91)
  • 1
    • 12844257556 scopus 로고    scopus 로고
    • Sizing it up: Cellular MRI using micron-sized iron oxide particles
    • Shapiro EM, Skrtic S, Koretsky AP: Sizing it up: cellular MRI using micron-sized iron oxide particles. Magn. Reson. Med. 53(2), 329-338 (2005).
    • (2005) Magn. Reson. Med. , vol.53 , Issue.2 , pp. 329-338
    • Shapiro, E.M.1    Skrtic, S.2    Koretsky, A.P.3
  • 2
    • 57649227456 scopus 로고    scopus 로고
    • Vivo labeling of adult neural progenitors for MRI with micron sized particles of iron oxide: Quantification of labeled cell phenotype
    • Sumner JP, Shapiro EM, Maric D, Conroy R, Koretsky AP: In vivo labeling of adult neural progenitors for MRI with micron sized particles of iron oxide: quantification of labeled cell phenotype. Neuroimage 44(3), 671-678 (2009).
    • (2009) Neuroimage , vol.44 , Issue.3 , pp. 671-678
    • Sumner, J.P.1    Shapiro, E.M.2    Maric, D.3    Conroy, R.4    Koretsky, A.P.5
  • 4
    • 33947521295 scopus 로고    scopus 로고
    • The in vitro effects of a bimodal contrast agent on cellular functions and relaxometry
    • Brekke C, Morgan SC, Lowe AS et al.: The in vitro effects of a bimodal contrast agent on cellular functions and relaxometry. NMR Biomed. 20(2), 77-89 (2007).
    • (2007) NMR Biomed. , vol.20 , Issue.2 , pp. 77-89
    • Brekke, C.1    Morgan, S.C.2    Lowe, A.S.3
  • 5
    • 67651151175 scopus 로고    scopus 로고
    • A chronic 1 year assessment of MRI contrast agent-labelled neural stem cell transplants in stroke
    • Modo M, Beech JS, Meade TJ, Williams SC, Price J: A chronic 1 year assessment of MRI contrast agent-labelled neural stem cell transplants in stroke. Neuroimage 47(Suppl. 2), T133-T142 (2008).
    • (2008) Neuroimage , vol.47 , Issue.SUPPL. 2
    • Modo, M.1    Beech, J.S.2    Meade, T.J.3    Williams, S.C.4    Price, J.5
  • 6
    • 57149111298 scopus 로고    scopus 로고
    • In vivo "hot spot"MR imaging of neural stem cells using fluorinated nanoparticles
    • Ruiz-Cabello J, Walczak P, Kedziorek DA et al.: In vivo "hot spot" MR imaging of neural stem cells using fluorinated nanoparticles. Magn. Reson. Med. 60(6), 1506-1511 (2008).
    • (2008) Magn. Reson. Med. , vol.60 , Issue.6 , pp. 1506-1511
    • Ruiz-Cabello, J.1    Walczak, P.2    Kedziorek, D.A.3
  • 8
    • 34249890215 scopus 로고    scopus 로고
    • MR-based imaging of neural stem cells
    • Politi LS: MR-based imaging of neural stem cells. Neuroradiology 49(6), 523-534 (2007).
    • (2007) Neuroradiology , vol.49 , Issue.6 , pp. 523-534
    • Politi, L.S.1
  • 9
    • 34548695230 scopus 로고    scopus 로고
    • Molecular neuroimaging: From conventional to emerging techniques
    • Hammoud DA, Hoffman JM, Pomper MG: Molecular neuroimaging: from conventional to emerging techniques. Radiology 245(1), 21-42 (2007).
    • (2007) Radiology , vol.245 , Issue.1 , pp. 21-42
    • Hammoud, D.A.1    Hoffman, J.M.2    Pomper, M.G.3
  • 10
    • 36849064645 scopus 로고    scopus 로고
    • Comparison of imaging techniques for tracking cardiac stem cell therapy
    • Zhang SJ, Wu JC: Comparison of imaging techniques for tracking cardiac stem cell therapy. J. Nucl. Med. 48(12), 1916-1919 (2007).
    • (2007) J. Nucl. Med. , vol.48 , Issue.12 , pp. 1916-1919
    • Zhang, S.J.1    Wu, J.C.2
  • 11
    • 33646155387 scopus 로고    scopus 로고
    • Understanding stem cell-mediated brain repair through neuroimaging
    • Modo M: Understanding stem cell-mediated brain repair through neuroimaging. Curr. Stem Cell Res. Ther. 1(1), 55-63 (2006).
    • (2006) Curr. Stem Cell Res. Ther. , vol.1 , Issue.1 , pp. 55-63
    • Modo, M.1
  • 12
    • 21244466333 scopus 로고    scopus 로고
    • MRI detection of macrophage activity after experimental stroke in rats: New indicators for late appearance of vascular degradation?
    • Weber R, Wegener S, Ramos-Cabrer P, Wiedermann D, Hoehn M: MRI detection of macrophage activity after experimental stroke in rats: new indicators for late appearance of vascular degradation? Magn. Reson. Med. 54(1), 59-66 (2005).
    • (2005) Magn. Reson. Med. , vol.54 , Issue.1 , pp. 59-66
    • Weber, R.1    Wegener, S.2    Ramos-Cabrer, P.3    Wiedermann, D.4    Hoehn, M.5
  • 13
    • 23444432500 scopus 로고    scopus 로고
    • In vivo imaging platform for tracking immunotherapeutic cells
    • Ahrens ET, Flores R, Xu H, Morel PA: In vivo imaging platform for tracking immunotherapeutic cells. Nat. Biotechnol. 23(8), 983-987 (2005).
    • (2005) Nat. Biotechnol. , vol.23 , Issue.8 , pp. 983-987
    • Ahrens, E.T.1    Flores, R.2    Xu, H.3    Morel, P.A.4
  • 14
    • 33751047338 scopus 로고    scopus 로고
    • Imaging stem cells implanted in infarcted myocardium
    • Zhou R, Acton PD, Ferrari VA: Imaging stem cells implanted in infarcted myocardium. J. Am. Coll. Cardiol. 48(10), 2094-2106 (2006).
    • (2006) J. Am. Coll. Cardiol. , vol.48 , Issue.10 , pp. 2094-2106
    • Zhou, R.1    Acton, P.D.2    Ferrari, V.A.3
  • 15
    • 33646776364 scopus 로고    scopus 로고
    • Transfection of neuroprogenitor cells with iron nanoparticles for magnetic resonance imaging tracking: Cell viability, differentiation, and intracellular localization
    • Miyoshi S, Flexman JA, Cross DJ et al.: Transfection of neuroprogenitor cells with iron nanoparticles for magnetic resonance imaging tracking: cell viability, differentiation, and intracellular localization. Mol. Imaging Biol. 7(4), 286-295 (2005).
    • (2005) Mol. Imaging Biol. , vol.7 , Issue.4 , pp. 286-295
    • Miyoshi, S.1    Flexman, J.A.2    Cross, D.J.3
  • 16
    • 40949154295 scopus 로고    scopus 로고
    • Efficient in vitro labeling of human neural precursor cells with superparamagnetic iron oxide particles: Relevance for in vivo cell tracking
    • Neri M, Maderna C, Cavazzin C et al.: Efficient in vitro labeling of human neural precursor cells with superparamagnetic iron oxide particles: relevance for in vivo cell tracking. Stem Cells 26(2), 505-516 (2008).
    • (2008) Stem Cells , vol.26 , Issue.2 , pp. 505-516
    • Neri, M.1    Maderna, C.2    Cavazzin, C.3
  • 17
    • 3843053490 scopus 로고    scopus 로고
    • Efficient magnetic cell labeling with protamine sulfate complexed to ferumoxides for cellular MRI
    • Arbab AS, Yocum GT, Kalish H et al.: Efficient magnetic cell labeling with protamine sulfate complexed to ferumoxides for cellular MRI. Blood 104(4), 1217-1223 (2004).
    • (2004) Blood , vol.104 , Issue.4 , pp. 1217-1223
    • Arbab, A.S.1    Yocum, G.T.2    Kalish, H.3
  • 19
    • 33745435248 scopus 로고    scopus 로고
    • Magnetoelectroporation: Improved labeling of neural stem cells and leukocytes for cellular magnetic resonance imaging using a single FDA-approved agent
    • Walczak P, Ruiz-Cabello J, Kedziorek DA et al.: Magnetoelectroporation: improved labeling of neural stem cells and leukocytes for cellular magnetic resonance imaging using a single FDA-approved agent. Nanomedicine 2(2), 89-94 (2006).
    • (2006) Nanomedicine , vol.2 , Issue.2 , pp. 89-94
    • Walczak, P.1    Ruiz-Cabello, J.2    Kedziorek, D.A.3
  • 20
    • 34547143397 scopus 로고    scopus 로고
    • Long-term monitoring of transplanted human neural stem cells in developmental and pathological contexts with MRI
    • Guzman R, Uchida N, Bliss TM et al.: Long-term monitoring of transplanted human neural stem cells in developmental and pathological contexts with MRI. Proc. Natl Acad. Sci. USA 104(24), 10211-10216 (2007).
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , Issue.24 , pp. 10211-10216
    • Guzman, R.1    Uchida, N.2    Bliss, T.M.3
  • 21
    • 34547959018 scopus 로고    scopus 로고
    • Applicability and limitations of MR tracking of neural stem cells with asymmetric cell division and rapid turnover: The case of the shiverer dysmyelinated mouse brain
    • Walczak P, Kedziorek DA, Gilad AA, Barnett BP, Bulte JW: Applicability and limitations of MR tracking of neural stem cells with asymmetric cell division and rapid turnover: the case of the shiverer dysmyelinated mouse brain. Magn. Reson. Med. 58(2), 261-269 (2007).
    • (2007) Magn. Reson. Med. , vol.58 , Issue.2 , pp. 261-269
    • Walczak, P.1    Kedziorek, D.A.2    Gilad, A.A.3    Barnett, B.P.4    Bulte, J.W.5
  • 22
    • 67349162449 scopus 로고    scopus 로고
    • Comparison of optical bioluminescence reporter gene and superparamagnetic iron oxide MR contrast agent as cell markers for noninvasive imaging of cardiac cell transplantation
    • Chen IY, Greve JM, Gheysens O et al.: Comparison of optical bioluminescence reporter gene and superparamagnetic iron oxide MR contrast agent as cell markers for noninvasive imaging of cardiac cell transplantation. Mol. Imaging Biol. 11(3), 178-187 (2009).
    • (2009) Mol. Imaging Biol. , vol.11 , Issue.3 , pp. 178-187
    • Chen, I.Y.1    Greve, J.M.2    Gheysens, O.3
  • 23
    • 14644420216 scopus 로고    scopus 로고
    • Ferritin as an endogenous MRI reporter for noninvasive imaging of gene expression in C6 glioma tumors
    • Cohen B, Dafni H, Meir G, Harmelin A, Neeman M: Ferritin as an endogenous MRI reporter for noninvasive imaging of gene expression in C6 glioma tumors. Neoplasia 7(2), 109-117 (2005).
    • (2005) Neoplasia , vol.7 , Issue.2 , pp. 109-117
    • Cohen, B.1    Dafni, H.2    Meir, G.3    Harmelin, A.4    Neeman, M.5
  • 24
    • 34147154719 scopus 로고    scopus 로고
    • MRI detection of transcriptional regulation of gene expression in transgenic mice
    • Cohen B, Ziv K, Plaks V et al.: MRI detection of transcriptional regulation of gene expression in transgenic mice. Nat. Med. 13(4), 498-503 (2007).
    • (2007) Nat. Med. , vol.13 , Issue.4 , pp. 498-503
    • Cohen, B.1    Ziv, K.2    Plaks, V.3
  • 25
    • 17644394164 scopus 로고    scopus 로고
    • A new transgene reporter for in vivo magnetic resonance imaging
    • Genove G, DeMarco U, Xu H, Goins WF, Ahrens ET: A new transgene reporter for in vivo magnetic resonance imaging. Nat. Med. 11(4), 450-454 (2005).
    • (2005) Nat. Med. , vol.11 , Issue.4 , pp. 450-454
    • Genove, G.1    Demarco, U.2    Xu, H.3    Goins, W.F.4    Ahrens, E.T.5
  • 26
    • 44949199326 scopus 로고    scopus 로고
    • MagA is sufficient for producing magnetic nanoparticles in mammalian cells, making it an MRI reporter
    • Zurkiya O, Chan AW, Hu X: MagA is sufficient for producing magnetic nanoparticles in mammalian cells, making it an MRI reporter. Magn. Reson. Med. 59(6), 1225-1231 (2008).
    • (2008) Magn. Reson. Med. , vol.59 , Issue.6 , pp. 1225-1231
    • Zurkiya, O.1    Chan, A.W.2    Hu, X.3
  • 27
    • 10644263595 scopus 로고    scopus 로고
    • Migration of iron oxide-labeled human hematopoietic progenitor cells in a mouse model: In vivo monitoring with 1.5-T MR imaging equipment
    • Daldrup-Link HE, Rudelius M, Piontek G et al.: Migration of iron oxide-labeled human hematopoietic progenitor cells in a mouse model: in vivo monitoring with 1.5-T MR imaging equipment. Radiology 234(1), 197-205 (2005).
    • (2005) Radiology , vol.234 , Issue.1 , pp. 197-205
    • Daldrup-Link, H.E.1    Rudelius, M.2    Piontek, G.3
  • 28
    • 12844271633 scopus 로고    scopus 로고
    • Detection threshold of single SPIO-labeled cells with FIESTA
    • Heyn C, Bowen CV, Rutt BK, Foster PJ: Detection threshold of single SPIO-labeled cells with FIESTA. Magn. Reson. Med. 53(2), 312-320 (2005).
    • (2005) Magn. Reson. Med. , vol.53 , Issue.2 , pp. 312-320
    • Heyn, C.1    Bowen, C.V.2    Rutt, B.K.3    Foster, P.J.4
  • 29
    • 30344471084 scopus 로고    scopus 로고
    • In vivo magnetic resonance imaging of single cells in mouse brain with optical validation
    • Heyn C, Ronald JA, Mackenzie LT et al.: In vivo magnetic resonance imaging of single cells in mouse brain with optical validation. Magn. Reson. Med. 55(1), 23-29 (2006).
    • (2006) Magn. Reson. Med. , vol.55 , Issue.1 , pp. 23-29
    • Heyn, C.1    Ronald, J.A.2    MacKenzie, L.T.3
  • 31
    • 0032938311 scopus 로고    scopus 로고
    • Detection of single mammalian cells by high-resolution magnetic resonance imaging
    • Dodd SJ, Williams M, Suhan JP, Williams DS, Koretsky AP, Ho C: Detection of single mammalian cells by high-resolution magnetic resonance imaging. Biophys. J. 76(1 Pt 1), 103-109 (1999).
    • (1999) Biophys. J. , vol.76 , Issue.1 PART 1 , pp. 103-109
    • Dodd, S.J.1    Williams, M.2    Suhan, J.P.3    Williams, D.S.4    Koretsky, A.P.5    Ho, C.6
  • 32
    • 29544452356 scopus 로고    scopus 로고
    • Labeling of cells with ferumoxides-protamine sulfate complexes does not inhibit function or differentiation capacity of hematopoietic or mesenchymal stem cells
    • Arbab AS, Yocum GT, Rad AM et al.: Labeling of cells with ferumoxides-protamine sulfate complexes does not inhibit function or differentiation capacity of hematopoietic or mesenchymal stem cells. NMR Biomed. 18(8), 553-559 (2005).
    • (2005) NMR Biomed. , vol.18 , Issue.8 , pp. 553-559
    • Arbab, A.S.1    Yocum, G.T.2    Rad, A.M.3
  • 33
    • 8644263269 scopus 로고    scopus 로고
    • Chondrogenic differentiation of mesenchymal stem cells is inhibited after magnetic labeling with ferumoxides
    • author reply 3412-3413
    • Bulte JW, Kraitchman DL, Mackay AM, Pittenger MF: Chondrogenic differentiation of mesenchymal stem cells is inhibited after magnetic labeling with ferumoxides. Blood 104(10), 3410-3412; author reply 3412-3413 (2004).
    • (2004) Blood , vol.104 , Issue.10 , pp. 3410-3412
    • Bulte, J.W.1    Kraitchman, D.L.2    MacKay, A.M.3    Pittenger, M.F.4
  • 34
    • 9244233296 scopus 로고    scopus 로고
    • Feridex labeling of mesenchymal stem cells inhibits chondrogenesis but not adipogenesis or osteogenesis
    • Kostura L, Kraitchman DL, Mackay AM, Pittenger MF, Bulte JW: Feridex labeling of mesenchymal stem cells inhibits chondrogenesis but not adipogenesis or osteogenesis. NMR Biomed. 17(7), 513-517 (2004).
    • (2004) NMR Biomed. , vol.17 , Issue.7 , pp. 513-517
    • Kostura, L.1    Kraitchman, D.L.2    MacKay, A.M.3    Pittenger, M.F.4    Bulte, J.W.5
  • 35
    • 29444439070 scopus 로고    scopus 로고
    • Development of functional human embryonic stem cell-derived neurons in mouse brain
    • Muotri AR, Nakashima K, Toni N, Sandler VM, Gage FH: Development of functional human embryonic stem cell-derived neurons in mouse brain. Proc. Natl Acad. Sci. USA 102(51), 18644-18648 (2005).
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , Issue.51 , pp. 18644-18648
    • Muotri, A.R.1    Nakashima, K.2    Toni, N.3    Sandler, V.M.4    Gage, F.H.5
  • 36
    • 0034687840 scopus 로고    scopus 로고
    • Direct isolation of human central nervous system stem cells
    • Uchida N, Buck DW, He D et al.: Direct isolation of human central nervous system stem cells. Proc. Natl Acad. Sci. USA 97(26) 14720-14725 (2000).
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , Issue.26 , pp. 14720-14725
    • Uchida, N.1    Buck, D.W.2    He, D.3
  • 37
    • 4143071470 scopus 로고    scopus 로고
    • Transplanted human fetal neural stem cells survive, migrate, and differentiate in ischemic rat cerebral cortex
    • Kelly S, Bliss TM, Shah AK et al.: Transplanted human fetal neural stem cells survive, migrate, and differentiate in ischemic rat cerebral cortex. Proc. Natl Acad. Sci. USA 101(32), 11839-11844 (2004).
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , Issue.32 , pp. 11839-11844
    • Kelly, S.1    Bliss, T.M.2    Shah, A.K.3
  • 38
    • 40549084702 scopus 로고    scopus 로고
    • Neural progenitor cells transplanted into the uninjured brain undergo targeted migration after stroke onset
    • Guzman R, Bliss T, De Los Angeles A, Moseley M, Palmer T, Steinberg G: Neural progenitor cells transplanted into the uninjured brain undergo targeted migration after stroke onset. J. Neurosci. Res. 86(4), 873-882 (2008).
    • (2008) J. Neurosci. Res. , vol.86 , Issue.4 , pp. 873-882
    • Guzman, R.1    Bliss, T.2    De Los Angeles, A.3    Moseley, M.4    Palmer, T.5    Steinberg, G.6
  • 39
    • 0037059050 scopus 로고    scopus 로고
    • Monitoring of implanted stem cell migration in vivo: A highly resolved in vivo magnetic resonance imaging investigation of experimental stroke in rat
    • Hoehn M, Kustermann E, Blunk J et al.: Monitoring of implanted stem cell migration in vivo: a highly resolved in vivo magnetic resonance imaging investigation of experimental stroke in rat. Proc. Natl Acad. Sci. USA 99(25), 16267-16272 (2002).
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , Issue.25 , pp. 16267-16272
    • Hoehn, M.1    Kustermann, E.2    Blunk, J.3
  • 40
    • 1642533659 scopus 로고    scopus 로고
    • Mapping transplanted stem cell migration after a stroke: A serial, in vivo magnetic resonance imaging study
    • Modo M, Mellodew K, Cash D et al.: Mapping transplanted stem cell migration after a stroke: a serial, in vivo magnetic resonance imaging study. Neuroimage 21(1), 311-317 (2004).
    • (2004) Neuroimage , vol.21 , Issue.1 , pp. 311-317
    • Modo, M.1    Mellodew, K.2    Cash, D.3
  • 41
    • 0037307904 scopus 로고    scopus 로고
    • Magnetic resonance imaging and neurosphere therapy of stroke in rat
    • Zhang ZG, Jiang Q, Zhang R et al.: Magnetic resonance imaging and neurosphere therapy of stroke in rat. Ann. Neurol. 53(2), 259-263 (2003).
    • (2003) Ann. Neurol. , vol.53 , Issue.2 , pp. 259-263
    • Zhang, Z.G.1    Jiang, Q.2    Zhang, R.3
  • 42
    • 67349231950 scopus 로고    scopus 로고
    • MRI tracking of intravenously transplanted human neural stem cells in rat focal ischemia model
    • Song M, Kim Y, Ryu S, Song I, Kim SU, Yoon BW: MRI tracking of intravenously transplanted human neural stem cells in rat focal ischemia model. Neurosci. Res. 64(2), 235-239 (2009).
    • (2009) Neurosci. Res. , vol.64 , Issue.2 , pp. 235-239
    • Song, M.1    Kim, Y.2    Ryu, S.3    Song, I.4    Kim, S.U.5    Yoon, B.W.6
  • 43
    • 44449176192 scopus 로고    scopus 로고
    • Dual-modality monitoring of targeted intraarterial delivery of mesenchymal stem cells after transient ischemia
    • Walczak P, Zhang J, Gilad AA et al.: Dual-modality monitoring of targeted intraarterial delivery of mesenchymal stem cells after transient ischemia. Stroke 39(5), 1569-1574 (2008).
    • (2008) Stroke , vol.39 , Issue.5 , pp. 1569-1574
    • Walczak, P.1    Zhang, J.2    Gilad, A.A.3
  • 44
    • 33846081868 scopus 로고    scopus 로고
    • Serial in vivo MR tracking of magnetically labeled neural spheres transplanted in chronic EAE mice
    • Ben-Hur T, van Heeswijk RB, Einstein O et al.: Serial in vivo MR tracking of magnetically labeled neural spheres transplanted in chronic EAE mice. Magn. Reson. Med. 57(1), 164-171 (2007).
    • (2007) Magn. Reson. Med. , vol.57 , Issue.1 , pp. 164-171
    • Ben-Hur, T.1    Van Heeswijk, R.B.2    Einstein, O.3
  • 45
    • 0033592971 scopus 로고    scopus 로고
    • Neurotransplantation of magnetically labeled oligodendrocyte progenitors: Magnetic resonance tracking of cell migration and myelination
    • Bulte JW, Zhang S, van Gelderen P et al.: Neurotransplantation of magnetically labeled oligodendrocyte progenitors: magnetic resonance tracking of cell migration and myelination. Proc. Natl Acad. Sci. USA 96(26), 15256-15261 (1999).
    • (1999) Proc. Natl Acad. Sci. USA , vol.96 , Issue.26 , pp. 15256-15261
    • Bulte, J.W.1    Zhang, S.2    Van Gelderen, P.3
  • 46
    • 35348920583 scopus 로고    scopus 로고
    • Magnetic-resonance-based tracking and quantification of intravenously injected neural stem cell accumulation in the brains of mice with experimental multiple sclerosis
    • Politi LS, Bacigaluppi M, Brambilla E et al.: Magnetic-resonance-based tracking and quantification of intravenously injected neural stem cell accumulation in the brains of mice with experimental multiple sclerosis. Stem Cells 25(10), 2583-2592 (2007).
    • (2007) Stem Cells , vol.25 , Issue.10 , pp. 2583-2592
    • Politi, L.S.1    Bacigaluppi, M.2    Brambilla, E.3
  • 47
    • 0034619328 scopus 로고    scopus 로고
    • Neural stem cells display extensive tropism for pathology in adult brain: Evidence from intracranial gliomas
    • Aboody KS, Brown A, Rainov NG et al.: Neural stem cells display extensive tropism for pathology in adult brain: evidence from intracranial gliomas. Proc. Natl Acad. Sci. USA 97(23), 12846-12851 (2000).
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , Issue.23 , pp. 12846-12851
    • Aboody, K.S.1    Brown, A.2    Rainov, N.G.3
  • 48
    • 0037115671 scopus 로고    scopus 로고
    • Induction of glioblastoma apoptosis using neural stem cell-mediated delivery of tumor necrosis factor-related apoptosis-inducing ligand
    • Ehtesham M, Kabos P, Gutierrez MA et al.: Induction of glioblastoma apoptosis using neural stem cell-mediated delivery of tumor necrosis factor-related apoptosis-inducing ligand. Cancer Res. 62(24), 7170-7174 (2002).
    • (2002) Cancer Res. , vol.62 , Issue.24 , pp. 7170-7174
    • Ehtesham, M.1    Kabos, P.2    Gutierrez, M.A.3
  • 49
    • 0034117480 scopus 로고    scopus 로고
    • Gene therapy of experimental brain tumors using neural progenitor cells
    • Benedetti S, Pirola B, Pollo B et al.: Gene therapy of experimental brain tumors using neural progenitor cells. Nat. Med. 6(4), 447-450 (2000).
    • (2000) Nat. Med. , vol.6 , Issue.4 , pp. 447-450
    • Benedetti, S.1    Pirola, B.2    Pollo, B.3
  • 50
    • 0346059589 scopus 로고    scopus 로고
    • Cellular and genetic characterization of human adult bone marrow-derived neural stem-like cells: A potential antiglioma cellular vector
    • Lee J, Elkahloun AG, Messina SA et al.: Cellular and genetic characterization of human adult bone marrow-derived neural stem-like cells: a potential antiglioma cellular vector. Cancer Res. 63(24), 8877-8889 (2003).
    • (2003) Cancer Res. , vol.63 , Issue.24 , pp. 8877-8889
    • Lee, J.1    Elkahloun, A.G.2    Messina, S.A.3
  • 51
    • 0033730294 scopus 로고    scopus 로고
    • Can neural stem cells be used to track down and destroy migratory brain tumor cells while also providing a means of repairing tumor-associated damage?
    • Noble M: Can neural stem cells be used to track down and destroy migratory brain tumor cells while also providing a means of repairing tumor-associated damage? Proc. Natl Acad. Sci. USA 97(23), 12393-12395 (2000).
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , Issue.23 , pp. 12393-12395
    • Noble, M.1
  • 52
    • 4344580303 scopus 로고    scopus 로고
    • In vivo magnetic resonance imaging tracks adult neural progenitor cell targeting of brain tumor
    • Zhang Z, Jiang Q, Jiang F et al.: In vivo magnetic resonance imaging tracks adult neural progenitor cell targeting of brain tumor. Neuroimage 23(1), 281-287 (2004).
    • (2004) Neuroimage , vol.23 , Issue.1 , pp. 281-287
    • Zhang, Z.1    Jiang, Q.2    Jiang, F.3
  • 53
    • 34547851774 scopus 로고    scopus 로고
    • Cellular multiparametric MRI of neural stem cell therapy in a rat glioma model
    • Brekke C, Williams SC, Price J, Thorsen F, Modo M: Cellular multiparametric MRI of neural stem cell therapy in a rat glioma model. Neuroimage 37(3), 769-782 (2007).
    • (2007) Neuroimage , vol.37 , Issue.3 , pp. 769-782
    • Brekke, C.1    Williams, S.C.2    Price, J.3    Thorsen, F.4    Modo, M.5
  • 54
    • 33751544180 scopus 로고    scopus 로고
    • Tracking neural stem cells in patients with brain trauma
    • Zhu J, Zhou L, XingWu F: Tracking neural stem cells in patients with brain trauma. N. Engl. J. Med. 355(22), 2376-2378 (2006).
    • (2006) N. Engl. J. Med. , vol.355 , Issue.22 , pp. 2376-2378
    • Zhu, J.1    Zhou, L.2    Xingwu, F.3
  • 55
    • 60549098262 scopus 로고    scopus 로고
    • Positron emission tomography imaging of poststroke angiogenesis
    • Cai W, Guzman R, Hsu AR et al.: Positron emission tomography imaging of poststroke angiogenesis. Stroke 40(1), 270-277 (2009).
    • (2009) Stroke , vol.40 , Issue.1 , pp. 270-277
    • Cai, W.1    Guzman, R.2    Hsu, A.R.3
  • 56
    • 67449083632 scopus 로고    scopus 로고
    • Multitracer assessment of dopamine function after transplantation of embryonic stem cell-derived neural stem cells in a primate model of Parkinson's disease
    • Muramatsu S, Okuno T, Suzuki Y et al.: Multitracer assessment of dopamine function after transplantation of embryonic stem cell-derived neural stem cells in a primate model of Parkinson's disease. Synapse 63(7), 541-548 (2009).
    • (2009) Synapse , vol.63 , Issue.7 , pp. 541-548
    • Muramatsu, S.1    Okuno, T.2    Suzuki, Y.3
  • 57
    • 0030928619 scopus 로고    scopus 로고
    • Gene therapy - Promises, problems and prospects
    • Verma IM, Somia N: Gene therapy - promises, problems and prospects. Nature 389(6648), 239-242 (1997).
    • (1997) Nature , vol.389 , Issue.6648 , pp. 239-242
    • Verma, I.M.1    Somia, N.2
  • 58
    • 6944232374 scopus 로고    scopus 로고
    • Robust in vivo gene transfer into adult mammalian neural stem cells by lentiviral vectors
    • Consiglio A, Gritti A, Dolcetta D et al.: Robust in vivo gene transfer into adult mammalian neural stem cells by lentiviral vectors. Proc. Natl Acad. Sci. USA 101(41), 14835-14840 (2004).
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , Issue.41 , pp. 14835-14840
    • Consiglio, A.1    Gritti, A.2    Dolcetta, D.3
  • 60
    • 0242385251 scopus 로고    scopus 로고
    • A mutant herpes simplex virus type 1 thymidine kinase reporter gene shows improved sensitivity for imaging reporter gene expression with positron emission tomography
    • Gambhir SS, Bauer E, Black ME et al.: A mutant herpes simplex virus type 1 thymidine kinase reporter gene shows improved sensitivity for imaging reporter gene expression with positron emission tomography. Proc. Natl Acad. Sci. USA 97(6), 2785-2790 (2000).
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , Issue.6 , pp. 2785-2790
    • Gambhir, S.S.1    Bauer, E.2    Black, M.E.3
  • 61
    • 67449110898 scopus 로고    scopus 로고
    • Conditional ablation and recovery of forebrain neurogenesis in the mouse
    • Singer BH, Jutkiewicz EM, Fuller CL et al.: Conditional ablation and recovery of forebrain neurogenesis in the mouse. J. Comp. Neurol. 514(6), 567-582 (2009).
    • (2009) J. Comp. Neurol. , vol.514 , Issue.6 , pp. 567-582
    • Singer, B.H.1    Jutkiewicz, E.M.2    Fuller, C.L.3
  • 62
    • 0036324348 scopus 로고    scopus 로고
    • Comparison of radiolabeled nucleoside probes (FIAU, FHBG, and FHPG) for PET imaging of HSV1-tk gene expression
    • Tjuvajev JG, Doubrovin M, Akhurst T et al.: Comparison of radiolabeled nucleoside probes (FIAU, FHBG, and FHPG) for PET imaging of HSV1-tk gene expression. J. Nucl. Med. 43(8), 1072-1083 (2002).
    • (2002) J. Nucl. Med. , vol.43 , Issue.8 , pp. 1072-1083
    • Tjuvajev, J.G.1    Doubrovin, M.2    Akhurst, T.3
  • 63
    • 63849134637 scopus 로고    scopus 로고
    • Multimodal imaging of neural progenitor cell fate in rodents
    • Waerzeggers Y, Klein M, Miletic H et al.: Multimodal imaging of neural progenitor cell fate in rodents. Mol. Imaging 7(2), 77-91 (2008).
    • (2008) Mol. Imaging , vol.7 , Issue.2 , pp. 77-91
    • Waerzeggers, Y.1    Klein, M.2    Miletic, H.3
  • 64
    • 27744493024 scopus 로고    scopus 로고
    • Mesenchymal stem cell targeting of microscopic tumors and tumor stroma development monitored by noninvasive in vivo positron emission tomography imaging
    • Hung SC, Deng WP, Yang WK et al.: Mesenchymal stem cell targeting of microscopic tumors and tumor stroma development monitored by noninvasive in vivo positron emission tomography imaging. Clin. Cancer Res. 11(21), 7749-7756 (2005).
    • (2005) Clin. Cancer Res. , vol.11 , Issue.21 , pp. 7749-7756
    • Hung, S.C.1    Deng, W.P.2    Yang, W.K.3
  • 65
    • 67650083560 scopus 로고    scopus 로고
    • Imaging gene expression in human mesenchymal stem cells: From small to large animals
    • Willmann JK, Paulmurugan R, Rodriguez-Porcel M et al.: Imaging gene expression in human mesenchymal stem cells: from small to large animals. Radiology 252, 117-127 (2009).
    • (2009) Radiology , vol.252 , pp. 117-127
    • Willmann, J.K.1    Paulmurugan, R.2    Rodriguez-Porcel, M.3
  • 66
    • 62649107264 scopus 로고    scopus 로고
    • Embryonic stem cell grafting in normal and infarcted myocardium: Serial assessment with MR imaging and PET dual detection
    • Qiao H, Zhang H, Zheng Y et al.: Embryonic stem cell grafting in normal and infarcted myocardium: serial assessment with MR imaging and PET dual detection. Radiology 250(3), 821-829 (2009).
    • (2009) Radiology , vol.250 , Issue.3 , pp. 821-829
    • Qiao, H.1    Zhang, H.2    Zheng, Y.3
  • 67
    • 0141653938 scopus 로고    scopus 로고
    • Molecular imaging of cardiac cell transplantation in living animals using optical bioluminescence and positron emission tomography
    • Wu JC, Chen IY, Sundaresan G et al.: Molecular imaging of cardiac cell transplantation in living animals using optical bioluminescence and positron emission tomography. Circulation 108(11), 1302-1305 (2003).
    • (2003) Circulation , vol.108 , Issue.11 , pp. 1302-1305
    • Wu, J.C.1    Chen, I.Y.2    Sundaresan, G.3
  • 68
    • 34250768170 scopus 로고    scopus 로고
    • Bystander killing of malignant glioma by bone marrow-derived tumor-infiltrating progenitor cells expressing a suicide gene
    • Miletic H, Fischer Y, Litwak S et al.: Bystander killing of malignant glioma by bone marrow-derived tumor-infiltrating progenitor cells expressing a suicide gene. Mol. Ther. 15(7), 1373-1381 (2007).
    • (2007) Mol. Ther. , vol.15 , Issue.7 , pp. 1373-1381
    • Miletic, H.1    Fischer, Y.2    Litwak, S.3
  • 69
    • 45849116863 scopus 로고    scopus 로고
    • The SPECT imaging shows the accumulation of neural progenitor cells into internal organs after systemic administration in middle cerebral artery occlusion rats
    • Lappalainen RS, Narkilahti S, Huhtala T et al.: The SPECT imaging shows the accumulation of neural progenitor cells into internal organs after systemic administration in middle cerebral artery occlusion rats. Neurosci. Lett. 440(3), 246-250 (2008).
    • (2008) Neurosci. Lett. , vol.440 , Issue.3 , pp. 246-250
    • Lappalainen, R.S.1    Narkilahti, S.2    Huhtala, T.3
  • 71
    • 80055113528 scopus 로고    scopus 로고
    • Labeling stem cells with fluorescent dyes for non-invasive detection with optical imaging
    • Boddington S, Henning TD, Sutton EJ, Daldrup-Link HE: Labeling stem cells with fluorescent dyes for non-invasive detection with optical imaging. J. Vis. Exp. 14, 686 (2008).
    • (2008) J. Vis. Exp. , vol.14 , pp. 686
    • Boddington, S.1    Henning, T.D.2    Sutton, E.J.3    Daldrup-Link, H.E.4
  • 72
    • 9144270498 scopus 로고    scopus 로고
    • Fluorescent peptide probes for in vivo diagnostic imaging
    • Tung CH: Fluorescent peptide probes for in vivo diagnostic imaging. Biopolymers 76(5), 391-403 (2004).
    • (2004) Biopolymers , vol.76 , Issue.5 , pp. 391-403
    • Tung, C.H.1
  • 73
    • 7444235966 scopus 로고    scopus 로고
    • In vivo near-infrared fluorescence imaging of integrin avb3 in brain tumor xenografts
    • Chen X, Conti PS, Moats RA: In vivo near-infrared fluorescence imaging of integrin avb3 in brain tumor xenografts. Cancer Res. 64(21), 8009-8014 (2004).
    • (2004) Cancer Res. , vol.64 , Issue.21 , pp. 8009-8014
    • Chen, X.1    Conti, P.S.2    Moats, R.A.3
  • 74
    • 0037983399 scopus 로고    scopus 로고
    • Fluorescence imaging with near-infrared light: New technological advances that enable in vivo molecular imaging
    • Ntziachristos V, Bremer C, Weissleder R: Fluorescence imaging with near-infrared light: new technological advances that enable in vivo molecular imaging. Eur. Radiol. 13(1), 195-208 (2003).
    • (2003) Eur. Radiol. , vol.13 , Issue.1 , pp. 195-208
    • Ntziachristos, V.1    Bremer, C.2    Weissleder, R.3
  • 75
    • 0348087040 scopus 로고    scopus 로고
    • Long-term multiple color imaging of live cells using quantum dot bioconjugates
    • Jaiswal JK, Mattoussi H, Mauro JM, Simon SM: Long-term multiple color imaging of live cells using quantum dot bioconjugates. Nat. Biotechnol. 21(1), 47-51 (2003).
    • (2003) Nat. Biotechnol. , vol.21 , Issue.1 , pp. 47-51
    • Jaiswal, J.K.1    Mattoussi, H.2    Mauro, J.M.3    Simon, S.M.4
  • 76
    • 33846370222 scopus 로고    scopus 로고
    • Imaging single events at the cell membrane
    • Jaiswal JK, Simon SM: Imaging single events at the cell membrane. Nat. Chem. Biol. 3(2), 92-98 (2007).
    • (2007) Nat. Chem. Biol. , vol.3 , Issue.2 , pp. 92-98
    • Jaiswal, J.K.1    Simon, S.M.2
  • 77
    • 0037416207 scopus 로고    scopus 로고
    • Fluorescence resonance energy transfer (FRET) microscopy imaging of live cell protein localizations
    • Sekar RB, Periasamy A: Fluorescence resonance energy transfer (FRET) microscopy imaging of live cell protein localizations. J. Cell Biol. 160(5), 629-633 (2003).
    • (2003) J. Cell Biol. , vol.160 , Issue.5 , pp. 629-633
    • Sekar, R.B.1    Periasamy, A.2
  • 78
    • 17844385071 scopus 로고    scopus 로고
    • Differential labeling of myosin v heads with quantum dots allows direct visualization of hand-over-hand processivity
    • Warshaw DM, Kennedy GG, Work SS, Krementsova EB, Beck S, Trybus KM: Differential labeling of myosin V heads with quantum dots allows direct visualization of hand-over-hand processivity. Biophys. J. 88(5), L30-L32 (2005).
    • (2005) Biophys. J. , vol.88 , Issue.5
    • Warshaw, D.M.1    Kennedy, G.G.2    Work, S.S.3    Krementsova, E.B.4    Beck, S.5    Trybus, K.M.6
  • 79
    • 31144475647 scopus 로고    scopus 로고
    • Forster resonance energy transfer investigations using quantum-dot fluorophores
    • Clapp AR, Medintz IL, Mattoussi H: Forster resonance energy transfer investigations using quantum-dot fluorophores. Chemphyschem 7(1), 47-57 (2006).
    • (2006) Chemphyschem , vol.7 , Issue.1 , pp. 47-57
    • Clapp, A.R.1    Medintz, I.L.2    Mattoussi, H.3
  • 80
    • 19944433260 scopus 로고    scopus 로고
    • Quantum dots for live cells, in vivo imaging, and diagnostics
    • Michalet X, Pinaud FF, Bentolila LA et al.: Quantum dots for live cells, in vivo imaging, and diagnostics. Science 307(5709), 538-544 (2005).
    • (2005) Science , vol.307 , Issue.5709 , pp. 538-544
    • Michalet, X.1    Pinaud, F.F.2    Bentolila, L.A.3
  • 82
    • 37249069890 scopus 로고    scopus 로고
    • In vivo quantum dot labeling of mammalian stem and progenitor cells
    • Slotkin JR, Chakrabarti L, Dai HN et al.: In vivo quantum dot labeling of mammalian stem and progenitor cells. Dev. Dyn. 236(12), 3393-3401 (2007).
    • (2007) Dev. Dyn. , vol.236 , Issue.12 , pp. 3393-3401
    • Slotkin, J.R.1    Chakrabarti, L.2    Dai, H.N.3
  • 83
    • 43749114031 scopus 로고    scopus 로고
    • Bimodal viral vectors and in vivo imaging reveal the fate of human neural stem cells in experimental glioma model
    • Shah K, Hingtgen S, Kasmieh R et al.: Bimodal viral vectors and in vivo imaging reveal the fate of human neural stem cells in experimental glioma model. J. Neurosci. 28(17), 4406-4413 (2008).
    • (2008) J. Neurosci. , vol.28 , Issue.17 , pp. 4406-4413
    • Shah, K.1    Hingtgen, S.2    Kasmieh, R.3
  • 84
    • 1842418723 scopus 로고    scopus 로고
    • Imaging of stem cell recruitment to ischemic infarcts in a murine model
    • Kim DE, Schellingerhout D, Ishii K, Shah K, Weissleder R: Imaging of stem cell recruitment to ischemic infarcts in a murine model. Stroke 35(4), 952-957 (2004).
    • (2004) Stroke , vol.35 , Issue.4 , pp. 952-957
    • Kim, D.E.1    Schellingerhout, D.2    Ishii, K.3    Shah, K.4    Weissleder, R.5
  • 85
    • 33846678019 scopus 로고    scopus 로고
    • Neural stem cell transplant survival in brains of mice: Assessing the effect of immunity and ischemia by using real-time bioluminescent imaging
    • Kim DE, Tsuji K, Kim YR et al.: Neural stem cell transplant survival in brains of mice: assessing the effect of immunity and ischemia by using real-time bioluminescent imaging. Radiology 241(3), 822-830 (2006).
    • (2006) Radiology , vol.241 , Issue.3 , pp. 822-830
    • Kim, D.E.1    Tsuji, K.2    Kim, Y.R.3
  • 86
    • 67649856579 scopus 로고    scopus 로고
    • Molecular and magnetic resonance imaging of human embryonic stem cell-derived neural stem cell grafts in ischemic rat brain
    • Daadi MM, Li Z, Arac A et al.: Molecular and magnetic resonance imaging of human embryonic stem cell-derived neural stem cell grafts in ischemic rat brain. Mol. Ther. 17(7), 1282-1291 (2009).
    • (2009) Mol. Ther. , vol.17 , Issue.7 , pp. 1282-1291
    • Daadi, M.M.1    Li, Z.2    Arac, A.3
  • 87
    • 72249088174 scopus 로고    scopus 로고
    • Noninvasive monitoring of embryonic stem cells in vivo with MRI transgene reporter
    • Epub ahead of print
    • Liu J, Cheng EC, Long RC Jr et al.: Noninvasive monitoring of embryonic stem cells in vivo with MRI transgene reporter. Tissue Eng. Part C Methods (2009) (Epub ahead of print).
    • (2009) Tissue Eng. Part C Methods
    • Liu, J.1    Cheng, E.C.2    Long Jr., R.C.3
  • 88
    • 0042475156 scopus 로고    scopus 로고
    • Development of a new reporter gene system - DsRed/xanthine phosphoribosyltransferase-xanthine for molecular imaging of processes behind the intact blood-brain barrier
    • Doubrovin M, Ponomarev V, Serganova I et al.: Development of a new reporter gene system - dsRed/xanthine phosphoribosyltransferase-xanthine for molecular imaging of processes behind the intact blood-brain barrier. Mol. Imaging 2(2), 93-112 (2003).
    • (2003) Mol. Imaging , vol.2 , Issue.2 , pp. 93-112
    • Doubrovin, M.1    Ponomarev, V.2    Serganova, I.3
  • 89
    • 14844284671 scopus 로고    scopus 로고
    • Combined inhibition of vascular endothelial growth factor and platelet-derived growth factor signaling: Effects on the angiogenesis, microcirculation, and growth of orthotopic malignant gliomas
    • Farhadi MR, Capelle HH, Erber R, Ullrich A, Vajkoczy P: Combined inhibition of vascular endothelial growth factor and platelet-derived growth factor signaling: effects on the angiogenesis, microcirculation, and growth of orthotopic malignant gliomas. J. Neurosurg. 102(2), 363-370 (2005).
    • (2005) J. Neurosurg. , vol.102 , Issue.2 , pp. 363-370
    • Farhadi, M.R.1    Capelle, H.H.2    Erber, R.3    Ullrich, A.4    Vajkoczy, P.5
  • 90


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