Evidence of interaction between type 2 diabetes susceptibility genes and dietary fat intake for adiposity and glucose homeostasis-related phenotypes

Journal of Nutrigenetics and Nutrigenomics

Volumn 2, Issue 4-5, 2010, Pages 225-234

  Ruchat, Stephanie May ^a,b   Elks, Cathy E ^c   Loos, Ruth J F ^c   Vohl, Marie Claude ^b,e   Weisnagel, S John ^a,b,e   Rankinen, Tuomo ^d   Bouchard, Claude ^d   Pérusse, Louis ^a,b,e  

^a UNIVERSITÉ LAVAL   (Canada)

^b LAVAL UNIVERSITY   (Canada)

^c INSTITUTE OF METABOLIC SCIENCE   (United Kingdom)

^d PENNINGTON BIOMEDICAL RESEARCH CENTER   (United States)

^e LAVAL UNIVERSITY   (Canada)

Author keywords

Adiposity; Diabetes susceptibility genes; Dietary fat; Gene diet interaction; Glucose homeostasis related phenotypes

Indexed keywords

CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE AL1; CYCLIN DEPENDENT KINASE INHIBITOR 2A; CYCLIN DEPENDENT KINASE INHIBITOR 2B; GENE PRODUCT; HEPATOCYTE NUCLEAR FACTOR 1BETA; INSULIN; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR6.2; PROTEIN HHEX; PROTEIN SLC30A8; PROTEIN WFS1; SOMATOMEDIN BINDING PROTEIN 2; TRANSCRIPTION FACTOR 7 LIKE 2; UNCLASSIFIED DRUG;

ABDOMINAL FAT; ADULT; ARTICLE; CANADA; CONTROLLED STUDY; FAT INTAKE; FEMALE; GENETIC SUSCEPTIBILITY; GENOTYPE ENVIRONMENT INTERACTION; GLUCOSE HOMEOSTASIS; GLUCOSE TOLERANCE; HUMAN; INSULIN SENSITIVITY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; ORAL GLUCOSE TOLERANCE TEST; PHENOTYPE; PRIORITY JOURNAL; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM;

ADIPOSITY; ADULT; BLOOD GLUCOSE; DIABETES MELLITUS, TYPE 2; DIET; DIETARY FATS; FAMILY; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; GLUCOSE; GLUCOSE TOLERANCE TEST; HOMEOSTASIS; HUMANS; INSULIN; MALE; MIDDLE AGED; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; QUEBEC; WAIST CIRCUMFERENCE;

EID: 77649278685     PISSN: 16616499     EISSN: 16616758     Source Type: Journal    
DOI: 10.1159/000259341     Document Type: Article

References (45)

1. WTCCC: Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007; 447: 661-678.
2. Gudmundsson J, Sulem P, Steinthorsdottir V, et al: Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes. Nat Genet 2007; 39: 977-983.
3. Saxena R, Voight BF, Lyssenko V, et al: Genome- wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science 2007; 316: 1331-1336.
4. Scott LJ, Mohlke KL, Bonnycastle LL, et al: A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. Science 2007; 316: 1341-1345.
5. Sladek R, Rocheleau G, Rung J, et al: A genome- wide association study identifies novel risk loci for type 2 diabetes. Nature 2007; 445: 881-885.
6. Steinthorsdottir V, Thorleifsson G, Reynisdottir I, et al: A variant in CDKAL1 influences insulin response and risk of type 2 diabetes. Nat Genet 2007; 39: 770-775.
7. Zeggini E, Weedon MN, Lindgren CM, et al: Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. Science 2007; 316: 1336-1341.
8. Zeggini E, Scott LJ, Saxena R, et al: Metaanalysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat Genet 2008;40:638-645.
9. Perry JR, Frayling TM: New gene variants alter type 2 diabetes risk predominantly through reduced beta-cell function. Curr Opin Clin Nutr Metab Care 2008; 11: 371-377.
10. Kaput J, Noble J, Hatipoglu B, Kohrs K, Dawson K, Bartholomew A: Application of nutrigenomic concepts to type 2 diabetes mellitus. Nutr Metab Cardiovasc Dis 2007; 17: 89-103.
11. Dedoussis GV, Kaliora AC, Panagiotakos DB: Genes, diet and type 2 diabetes mellitus: a review. Rev Diabet Stud 2007; 4: 13-24.
12. Franks PW, Mesa JL, Harding AH, Wareham NJ: Gene-lifestyle interaction on risk of type 2 diabetes. Nutr Metab Cardiovasc Dis 2007; 17: 104-124.
13. Florez JC, Jablonski KA, Bayley N, et al: TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program. N Engl J Med 2006; 355: 241-250.
14. Moore AF, Jablonski KA, McAteer JB, et al: Extension of type 2 diabetes genome-wide association scan results in the diabetes prevention program. Diabetes 2008; 57: 2503-2510
15. Brito EC, Lyssenko V, Renstrom F, et al: Previously associated type 2 diabetes variants may interact with physical activity to modify the risk of impaired glucose regulation and type 2 diabetes: a study of 16,003 Swedish adults. Diabetes 2009; 7: 7.
16. Muller M, Kersten S: Nutrigenomics: goals and strategies. Nat Rev Genet 2003; 4: 315-322.
17. Doria A, Patti ME, Kahn CR: The emerging genetic architecture of type 2 diabetes. Cell Metab 2008; 8: 186-200.
18. Bouchard C: Genetic epidemiology, association and sib-pair linkage: results from the Quebec Family Study; in Bray G, Ryan D (eds): Molecular and Genetic Aspects of Obesity. Baton Rouge, Louisiana State University Press, 1994, pp 470-481.
19. WHO: Definition, Diagnosis and Classification of Diabetes Mellitus and Its Complications. Geneva, WHO; 1999.
20. Lohman T, Roche A, Martorell F (eds): Anthropometric Standardization Reference Manual. Champaign, Human Kinetics, 1988.
21. Siri WE: The gross composition of the body. Adv Biol Med Phys 1956; 4: 239-280.
22. Ferland M, Despres JP, Tremblay A, et al: Assessment of adipose tissue distribution by computed axial tomography in obese women: association with body density and anthropometric measurements. Br J Nutr 1989; 61: 139-148.
23. Rice T, Nadeau A, Perusse L, Bouchard C, Rao DC: Familial correlations in the Quebec Family Study: cross-trait familial resemblance for body fat with plasma glucose and insulin. Diabetologia 1996; 39: 1357-1364.
24. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC: Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985; 28: 412-419.
25. Cederholm J, Wibell L: Insulin release and peripheral sensitivity at the oral glucose tolerance test. Diabetes Res Clin Pract 1990; 10: 167-175.
26. Bergstrom RW, Wahl PW, Leonetti DL, Fujimoto WY: Association of fasting glucose levels with a delayed secretion of insulin after oral glucose in subjects with glucose intolerance. J Clin Endocrinol Metab 1990; 71: 1447-1453.
27. Bergman RN, Ader M, Huecking K, Van Citters G: Accurate assessment of beta-cell function: the hyperbolic correction. Diabetes 2002; 51(suppl 1):S212-S220.
28. Hanson RL, Pratley RE, Bogardus C, et al: Evaluation of simple indices of insulin sensitivity and insulin secretion for use in epidemiologic studies. Am J Epidemiol 2000; 151: 190-198.
29. Stumvoll M, Mitrakou A, Pimenta W, et al: Use of the oral glucose tolerance test to assess insulin release and insulin sensitivity. Diabetes Care 2000; 23: 295-301.
30. Tremblay A, Sévigny J, Leblanc C, et al: The reproductibility of a three-day dietary record. Nutr Res 1983;3:819-830.
31. Gibson RS: Measuring food consumption in individuals; in Principles of Nutritional Assessment. Oxford, Oxford University Press, 2005, pp 41-64.
32. Thompson FE, Subar AF: Dietary assessment methodology; in Coulston AM, Rock C, Monsen ER (eds): Nutrition in the Prevention and Treatment of Disease. San Diego, Academic Press, 2001, pp 3-30.
33. Ruchat SM, Elks CE, Loos RJ, et al: Association between insulin secretion, insulin sensitivity and type 2 diabetes susceptibility variants identified in genome-wide association studies. Acta Diabetol 2009; 46: 217-226.
34. Livak KJ: Allelic discrimination using fluorogenic probes and the 5 nuclease assay. Genet Anal 1999; 14: 143-149.
35. O'Connell JR, Weeks DE: PedCheck: a program for identification of genotype incompatibilities in linkage analysis. Am J Hum Genet 1998; 63: 259-266.
36. Devlin B, Risch N: A comparison of linkage disequilibrium measures for fine-scale mapping. Genomics 1995; 29: 311-322.
37. Lohmueller KE, Pearce CL, Pike M, Lander ES, Hirschhorn JN: Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease. Nat Genet 2003; 33: 177-182.
38. Dietary Guidelines for Americans - Adequate Nutrients within Calorie Needs. United States Department of Agriculture (USDA), 2005.
39. Dietary Reference Intakes for Energy, Carbohydrate, Fiber, Fat, Fatty Acids, Cholesterol, Protein, and Amino Acids (Macronutrients). Health Canada, 2005.
40. Rodriguez S, Gaunt TR, Day IN: Molecular genetics of human growth hormone, insulin- like growth factors and their pathways in common disease. Hum Genet 2007; 122: 1-21.
41. Heald A, Stephens R, Gibson JM: The insulin- like growth factor system and diabetes- an overview. Diabet Med 2006; 23(suppl 1):19-24.
42. Province MA, Borecki IB: Gathering the gold dust: methods for assessing the aggregate impact of small effect genes in genomic scans. Pac Symp Biocomput, 2008, pp 190- 200.
43. Sabatti C, Service SK, Hartikainen AL, et al: Genome-wide association analysis of metabolic traits in a birth cohort from a founder population. Nat Genet 2009; 41: 35-46.
44. Prokopenko I, Langenberg C, Florez JC, et al: Variants in MTNR1B influence fasting glucose levels. Nat Genet 2009; 41: 77-81.
45. Bouatia-Naji N, Bonnefond A, Cavalcanti- Proenca C, et al: A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk. Nat Genet 2009; 41: 89-94.