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Volumn 51, Issue 15, 2010, Pages 1989-1993

Synthetic studies toward the development of novel minoxidil analogs and conjugates with polyamines

Author keywords

Minoxidil; N,N Carbonyldiimidazole; N Oxides; Nucleophilic aromatic substitution; Polyamine conjugates; Pyrimidines

Indexed keywords

MINOXIDIL; MINOXIDIL DERIVATIVE; POLYAMINE DERIVATIVE; UNCLASSIFIED DRUG;

EID: 77649275279     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2010.02.037     Document Type: Article
Times cited : (12)

References (46)
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    • Recently, solubility studies of minoxidil in water in the form of inclusion complexes with β-CD have been described in:
    • Recently, solubility studies of minoxidil in water in the form of inclusion complexes with β-CD have been described in:. Calderini A., and Pessine F.B.T. J. Incl. Phemon. Macrocycl. Chem. 60 (2008) 369
    • (2008) J. Incl. Phemon. Macrocycl. Chem. , vol.60 , pp. 369
    • Calderini, A.1    Pessine, F.B.T.2
  • 24
    • 0021040644 scopus 로고
    • For selected examples of other minoxidil derivatives, their synthesis and mode of action, see:
    • For selected examples of other minoxidil derivatives, their synthesis and mode of action, see:. McCall J.M., Aiken J.W., Chidester C.G., DuCharme D.W., and Wendling M.G. J. Med. Chem. 26 (1983) 1791
    • (1983) J. Med. Chem. , vol.26 , pp. 1791
    • McCall, J.M.1    Aiken, J.W.2    Chidester, C.G.3    DuCharme, D.W.4    Wendling, M.G.5
  • 29
    • 77649270435 scopus 로고    scopus 로고
    • note
    • Part of this work was presented in the form of a poster at the 10th Tetrahedron Symposium, Paris, 2009, Abstract Book (P C132).
  • 31
    • 0036532331 scopus 로고    scopus 로고
    • The preparation, in only 31% yield (see however Supplementary data), and the characterization of 2 was subsequently described in:
    • The preparation, in only 31% yield (see however Supplementary data), and the characterization of 2 was subsequently described in:. Vassis S., Govaris I., Voyatzi K., Mamos P., and Papaioannou D. Tetrahedron Lett. 43 (2002) 2597
    • (2002) Tetrahedron Lett. , vol.43 , pp. 2597
    • Vassis, S.1    Govaris, I.2    Voyatzi, K.3    Mamos, P.4    Papaioannou, D.5
  • 34
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    • The preparation of this compound (see Supplementary data) initially required selective protection of the primary amino functions using the trifluoroacetyl group as described in:
    • The preparation of this compound (see Supplementary data) initially required selective protection of the primary amino functions using the trifluoroacetyl group as described in:. O'Sullivan M.C., and Dalrymple D.M. Tetrahedron Lett. 36 (1995) 3451
    • (1995) Tetrahedron Lett. , vol.36 , pp. 3451
    • O'Sullivan, M.C.1    Dalrymple, D.M.2
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    • Allaigre, J. P.; Desbois, J. FR. Patent 2,632,954, 1989; Chem. Abstr. 1989, 113, 212009.
    • Allaigre, J. P.; Desbois, J. FR. Patent 2,632,954, 1989; Chem. Abstr. 1989, 113, 212009.
  • 44


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.