Inhibition of anticancer drug efflux transporter P-glycoprotein by rosemary phytochemicals

Pharmacological Research

Volumn 61, Issue 3, 2010, Pages 259-263

  Nabekura, Tomohiro ^a   Yamaki, Takeshi ^a   Hiroi, Takashi ^a   Ueno, Kazuyuki ^a   Kitagawa, Shuji ^b  

^a NIIGATA UNIVERSITY OF PHARMACY AND APPLIED LIFE SCIENCES   (Japan)

^b KOBE PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Anticancer drug; Drug transporter; P glycoprotein; Phytochemical; Rosemary

Indexed keywords

ADENOSINE TRIPHOSPHATASE; CALCEIN; CARNOSIC ACID; CARNOSOL; DAUNORUBICIN; GLYCOPROTEIN P; MULTIDRUG RESISTANCE PROTEIN 1; PLANT MEDICINAL PRODUCT; RHODAMINE 123; ROSMARINIC ACID; URSOLIC ACID; VINBLASTINE; ANTINEOPLASTIC AGENT; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1; PLANT EXTRACT;

ARTICLE; CANCER CELL; CANCER CHEMOTHERAPY; CELL STRAIN KB; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOTOXICITY; DRUG MECHANISM; DRUG POTENTIATION; DRUG SCREENING; DRUG STRUCTURE; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN CELL; MULTIDRUG RESISTANCE; PRIORITY JOURNAL; PROTEIN FUNCTION; ROSEMARY; ANTAGONISTS AND INHIBITORS; CHEMISTRY; COMPARATIVE STUDY; ISOLATION AND PURIFICATION; KB CELL LINE; METABOLISM; PHYSIOLOGY; PHYTOTHERAPY; PLANT LEAF; ROSMARINUS;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; DAUNORUBICIN; HUMANS; KB CELLS; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; P-GLYCOPROTEIN; PHYTOTHERAPY; PLANT EXTRACTS; PLANT LEAVES; ROSMARINUS;

EID: 77649274473     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2009.11.010     Document Type: Article

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