Sodium permeability and sensitivity induced by mutations in the selectivity filter of the KcsA channel towards Kir channels

Biochimie

Volumn 92, Issue 3, 2010, Pages 232-244

  Raja, Mobeen ^a   Vales, Elisabeth ^a  

^a JOHANNES KEPLER UNIVERSITY LINZ   (Austria)

Author keywords

Inwardly rectifying K+ channel; Ion ion interaction; K+ channel KcsA; Mutation; Selectivity filter; Sodium permeability; Tetramer stability

Indexed keywords

BACTERIAL PROTEIN; BARIUM; INWARDLY RECTIFYING POTASSIUM CHANNEL; POTASSIUM CHANNEL; POTASSIUM CHANNEL KCSA; PROTEIN T74V; PROTEIN V76I; TETRAMER; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; ESCHERICHIA COLI; FLUORESCENCE; GENE MUTATION; IMMUNOBLOTTING; ION PERMEABILITY; NONHUMAN; POINT MUTATION; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN STABILITY; SITE DIRECTED MUTAGENESIS; SODIUM PERMEABILITY; SODIUM TRANSPORT;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; BARIUM; ION CHANNEL GATING; LIPID BILAYERS; LIPOSOMES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PATCH-CLAMP TECHNIQUES; POINT MUTATION; POTASSIUM; POTASSIUM CHANNELS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PROTEIN CONFORMATION; PROTEIN FOLDING; SEQUENCE ALIGNMENT; SODIUM;

BACTERIA (MICROORGANISMS);

EID: 77649271426     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2009.11.007     Document Type: Article

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