Use of DNA-damaging agents and RNA pooling to assess expression profiles associated with BRCA1 and BRCA2 mutation status in familial breast cancer patients

PLoS Genetics

Volumn 6, Issue 2, 2010, Pages

  Walker, Logan C ^a   Thompson, Bryony A ^a   Waddell, Nic ^a   Thorne, Heather ^b   Niedermayr, Eveline ^b   Grimmond, Sean M ^c   Spurdle, Amanda B ^a  

^a QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^b PETER MACCALLUM CANCER CENTRE   (Australia)

^c UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN; DNA; MITOMYCIN C; MITOMYCIN; RNA;

ARTICLE; BREAST CANCER; CANCER PATIENT; CANCER RADIOTHERAPY; CONTROLLED STUDY; DNA DAMAGE; FEMALE; GENE EXPRESSION; GENE MUTATION; HIGH RISK PATIENT; HUMAN; HUMAN CELL; LYMPHOBLASTOID CELL LINE; ONCOGENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; BREAST TUMOR; CLASSIFICATION; DRUG EFFECT; FAMILY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; IONIZING RADIATION; METABOLISM; MUTATION; RADIATION EXPOSURE; REPRODUCIBILITY; TUMOR CELL LINE; TUMOR GENE;

BRCA1 PROTEIN; BRCA2 PROTEIN; BREAST NEOPLASMS; CELL LINE, TUMOR; DNA DAMAGE; FAMILY; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, NEOPLASM; HUMANS; MITOMYCIN; MUTATION; RADIATION, IONIZING; REPRODUCIBILITY OF RESULTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, NEOPLASM;

EID: 77649229346     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1000850     Document Type: Article

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