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Volumn 112, Issue 2, 2008, Pages 229-236

Use of expression data and the CGEMS genome-wide breast cancer association study to identify genes that may modify risk in BRCA1/2 mutation carriers

Author keywords

BRCA1; BRCA2; BRCAX; Breast cancer; Cancer Genetic Markers of Susceptibilty (CGEMS); Cell cycle; Irradiation; Microarray; Modifier genes

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN;

EID: 53949111816     PISSN: 01676806     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10549-007-9848-5     Document Type: Article
Times cited : (11)

References (41)
  • 2
    • 0038744296 scopus 로고    scopus 로고
    • Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case Series unselected for family history: A combined analysis of 22 studies
    • 5
    • A Antoniou PD Pharoah S Narod 2003 Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case Series unselected for family history: a combined analysis of 22 studies Am J Hum Genet 72 5 1117 1130
    • (2003) Am J Hum Genet , vol.72 , pp. 1117-1130
    • Antoniou, A.1    Pharoah, P.D.2    Narod, S.3
  • 3
    • 33644865633 scopus 로고    scopus 로고
    • Familial clustering of site-specific cancer risks associated with BRCA1 and BRCA2 mutations in the Ashkenazi Jewish population
    • 10
    • S Simchoni E Friedman B Kaufman 2006 Familial clustering of site-specific cancer risks associated with BRCA1 and BRCA2 mutations in the Ashkenazi Jewish population Proc Natl Acad Sci USA 103 10 3770 3774
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 3770-3774
    • Simchoni, S.1    Friedman, E.2    Kaufman, B.3
  • 4
    • 33846425741 scopus 로고    scopus 로고
    • Phenocopies in BRCA1 and BRCA2 families: Evidence for modifier genes and implications for screening
    • 1
    • A Smith A Moran MC Boyd 2007 Phenocopies in BRCA1 and BRCA2 families: evidence for modifier genes and implications for screening J Med Genet 44 1 10 15
    • (2007) J Med Genet , vol.44 , pp. 10-15
    • Smith, A.1    Moran, A.2    Boyd, M.C.3
  • 5
    • 36749002743 scopus 로고    scopus 로고
    • RAD51 135G>C modifies breast cancer risk among BRCA2 mutation carriers: Results from a combined analysis of 19 studies
    • 6
    • AC Antoniou OM Sinilnikova J Simard 2007 RAD51 135G>C modifies breast cancer risk among BRCA2 mutation carriers: results from a combined analysis of 19 studies Am J Hum Genet 81 6 1186 1200
    • (2007) Am J Hum Genet , vol.81 , pp. 1186-1200
    • Antoniou, A.C.1    Sinilnikova, O.M.2    Simard, J.3
  • 6
    • 33645226075 scopus 로고    scopus 로고
    • A haplotype containing the p53 polymorphisms Ins16bp and Arg72Pro modifies cancer risk in BRCA2 mutation carriers
    • 3
    • A Osorio B Martinez-Delgado M Pollan 2006 A haplotype containing the p53 polymorphisms Ins16bp and Arg72Pro modifies cancer risk in BRCA2 mutation carriers Hum Mutat 27 3 242 248
    • (2006) Hum Mutat , vol.27 , pp. 242-248
    • Osorio, A.1    Martinez-Delgado, B.2    Pollan, M.3
  • 7
    • 0001516492 scopus 로고    scopus 로고
    • Modification of BRCA1-associated breast cancer risk by the polymorphic androgen-receptor CAG repeat
    • 5
    • TR Rebbeck PW Kantoff K Krithivas 1999 Modification of BRCA1-associated breast cancer risk by the polymorphic androgen-receptor CAG repeat Am J Hum Genet 64 5 1371 1377
    • (1999) Am J Hum Genet , vol.64 , pp. 1371-1377
    • Rebbeck, T.R.1    Kantoff, P.W.2    Krithivas, K.3
  • 8
    • 0035878970 scopus 로고    scopus 로고
    • Modification of BRCA1- and BRCA2-associated breast cancer risk by AIB1 genotype and reproductive history
    • 14
    • TR Rebbeck Y Wang PW Kantoff 2001 Modification of BRCA1- and BRCA2-associated breast cancer risk by AIB1 genotype and reproductive history Cancer Res 61 14 5420 5424
    • (2001) Cancer Res , vol.61 , pp. 5420-5424
    • Rebbeck, T.R.1    Wang, Y.2    Kantoff, P.W.3
  • 9
    • 29344471975 scopus 로고    scopus 로고
    • The androgen receptor CAG repeat polymorphism and modification of breast cancer risk in BRCA1 and BRCA2 mutation carriers
    • 2
    • AB Spurdle AC Antoniou DL Duffy 2005 The androgen receptor CAG repeat polymorphism and modification of breast cancer risk in BRCA1 and BRCA2 mutation carriers Breast Cancer Res 7 2 R176 R183
    • (2005) Breast Cancer Res , vol.7
    • Spurdle, A.B.1    Antoniou, A.C.2    Duffy, D.L.3
  • 10
    • 33645449964 scopus 로고    scopus 로고
    • The AIB1 polyglutamine repeat does not modify breast cancer risk in BRCA1 and BRCA2 mutation carriers
    • 1
    • AB Spurdle AC Antoniou L Kelemen 2006 The AIB1 polyglutamine repeat does not modify breast cancer risk in BRCA1 and BRCA2 mutation carriers Cancer Epidemiol Biomarkers Prev 15 1 76 79
    • (2006) Cancer Epidemiol Biomarkers Prev , vol.15 , pp. 76-79
    • Spurdle, A.B.1    Antoniou, A.C.2    Kelemen, L.3
  • 11
    • 0034031137 scopus 로고    scopus 로고
    • DNA double strand break repair in mammalian cells
    • 2
    • P Karran 2000 DNA double strand break repair in mammalian cells Curr Opin Genet Dev 10 2 144 150
    • (2000) Curr Opin Genet Dev , vol.10 , pp. 144-150
    • Karran, P.1
  • 12
    • 33748559470 scopus 로고    scopus 로고
    • A region of human BRCA2 containing multiple BRC repeats promotes RAD51-mediated strand exchange
    • 14
    • MK Shivji OR Davies JM Savill 2006 A region of human BRCA2 containing multiple BRC repeats promotes RAD51-mediated strand exchange Nucleic Acids Res 34 14 4000 4011
    • (2006) Nucleic Acids Res , vol.34 , pp. 4000-4011
    • Shivji, M.K.1    Davies, O.R.2    Savill, J.M.3
  • 13
    • 34250197864 scopus 로고    scopus 로고
    • Identification of women with an increased risk of developing radiation-induced breast cancer: A case only study
    • 2
    • A Broeks LM Braaf A Huseinovic 2007 Identification of women with an increased risk of developing radiation-induced breast cancer: a case only study Breast Cancer Res 9 2 R26
    • (2007) Breast Cancer Res , vol.9 , pp. 26
    • Broeks, A.1    Braaf, L.M.2    Huseinovic, A.3
  • 14
    • 33749000596 scopus 로고    scopus 로고
    • The role of BRCA1 in transcriptional regulation and cell cycle control
    • 43
    • PB Mullan JE Quinn DP Harkin 2006 The role of BRCA1 in transcriptional regulation and cell cycle control Oncogene 25 43 5854 5863
    • (2006) Oncogene , vol.25 , pp. 5854-5863
    • Mullan, P.B.1    Quinn, J.E.2    Harkin, D.P.3
  • 15
    • 0035951405 scopus 로고    scopus 로고
    • A human BRCA2 complex containing a structural DNA binding component influences cell cycle progression
    • 2
    • LY Marmorstein AV Kinev GK Chan 2001 A human BRCA2 complex containing a structural DNA binding component influences cell cycle progression Cell 104 2 247 257
    • (2001) Cell , vol.104 , pp. 247-257
    • Marmorstein, L.Y.1    Kinev, A.V.2    Chan, G.K.3
  • 16
    • 33644949696 scopus 로고    scopus 로고
    • Analysis of cancer risk and BRCA1 and BRCA2 mutation prevalence in the kConFab familial breast cancer resource
    • 1
    • GJ Mann H Thorne RL Balleine 2006 Analysis of cancer risk and BRCA1 and BRCA2 mutation prevalence in the kConFab familial breast cancer resource Breast Cancer Res 8 1 R12
    • (2006) Breast Cancer Res , vol.8 , pp. 12
    • Mann, G.J.1    Thorne, H.2    Balleine, R.L.3
  • 17
    • 35348930441 scopus 로고    scopus 로고
    • Mutation analysis of five candidate genes in familial breast cancer
    • 3
    • A Marsh S Healey A Lewis 2007 Mutation analysis of five candidate genes in familial breast cancer Breast Cancer Res Treat 105 3 377 389
    • (2007) Breast Cancer Res Treat , vol.105 , pp. 377-389
    • Marsh, A.1    Healey, S.2    Lewis, A.3
  • 18
    • 33644549954 scopus 로고    scopus 로고
    • Genetic and histopathologic evaluation of BRCA1 and BRCA2 DNA sequence variants of unknown clinical significance
    • 4
    • G Chenevix-Trench S Healey S Lakhani 2006 Genetic and histopathologic evaluation of BRCA1 and BRCA2 DNA sequence variants of unknown clinical significance Cancer Res 66 4 2019 2027
    • (2006) Cancer Res , vol.66 , pp. 2019-2027
    • Chenevix-Trench, G.1    Healey, S.2    Lakhani, S.3
  • 19
    • 0141853958 scopus 로고    scopus 로고
    • Transcriptional response of lymphoblastoid cells to ionizing radiation
    • 9
    • KY Jen VG Cheung 2003 Transcriptional response of lymphoblastoid cells to ionizing radiation Genome Res 13 9 2092 2100
    • (2003) Genome Res , vol.13 , pp. 2092-2100
    • Jen, K.Y.1    Cheung, V.G.2
  • 20
    • 35948953262 scopus 로고    scopus 로고
    • Power to detect risk alleles using genome-wide tag SNP panels
    • 10
    • MA Eberle PC Ng K Kuhn 2007 Power to detect risk alleles using genome-wide tag SNP panels PLoS Genet 3 10 1827 1837
    • (2007) PLoS Genet , vol.3 , pp. 1827-1837
    • Eberle, M.A.1    Ng, P.C.2    Kuhn, K.3
  • 21
    • 34250006413 scopus 로고    scopus 로고
    • Genome-wide association study identifies novel breast cancer susceptibility loci
    • 7148
    • DF Easton KA Pooley AM Dunning 2007 Genome-wide association study identifies novel breast cancer susceptibility loci Nature 447 7148 1087 1093
    • (2007) Nature , vol.447 , pp. 1087-1093
    • Easton, D.F.1    Pooley, K.A.2    Dunning, A.M.3
  • 22
    • 0037499970 scopus 로고    scopus 로고
    • MatchMiner: A tool for batch navigation among gene and gene product identifiers
    • 4
    • KJ Bussey D Kane M Sunshine 2003 MatchMiner: a tool for batch navigation among gene and gene product identifiers Genome Biol 4 4 R27
    • (2003) Genome Biol , vol.4 , pp. 27
    • Bussey, K.J.1    Kane, D.2    Sunshine, M.3
  • 23
    • 33646570913 scopus 로고    scopus 로고
    • A genome wide linkage search for breast cancer susceptibility genes
    • 7
    • P Smith L McGuffog DF Easton 2006 A genome wide linkage search for breast cancer susceptibility genes Genes Chromosomes Cancer 45 7 646 655
    • (2006) Genes Chromosomes Cancer , vol.45 , pp. 646-655
    • Smith, P.1    McGuffog, L.2    Easton, D.F.3
  • 24
    • 33847337318 scopus 로고    scopus 로고
    • A common coding variant in CASP8 is associated with breast cancer risk
    • 3
    • A Cox AM Dunning M Garcia-Closas 2007 A common coding variant in CASP8 is associated with breast cancer risk Nat Genet 39 3 352 358
    • (2007) Nat Genet , vol.39 , pp. 352-358
    • Cox, A.1    Dunning, A.M.2    Garcia-Closas, M.3
  • 25
    • 33846625493 scopus 로고    scopus 로고
    • PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene
    • 2
    • N Rahman S Seal D Thompson 2007 PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene Nat Genet 39 2 165 167
    • (2007) Nat Genet , vol.39 , pp. 165-167
    • Rahman, N.1    Seal, S.2    Thompson, D.3
  • 26
    • 33746491583 scopus 로고    scopus 로고
    • ATM mutations that cause ataxia-telangiectasia are breast cancer susceptibility alleles
    • 8
    • A Renwick D Thompson S Seal 2006 ATM mutations that cause ataxia-telangiectasia are breast cancer susceptibility alleles Nat Genet 38 8 873 875
    • (2006) Nat Genet , vol.38 , pp. 873-875
    • Renwick, A.1    Thompson, D.2    Seal, S.3
  • 27
    • 33750465216 scopus 로고    scopus 로고
    • Truncating mutations in the Fanconi anemia J gene BRIP1 are low-penetrance breast cancer susceptibility alleles
    • 11
    • S Seal D Thompson A Renwick 2006 Truncating mutations in the Fanconi anemia J gene BRIP1 are low-penetrance breast cancer susceptibility alleles Nat Genet 38 11 1239 1241
    • (2006) Nat Genet , vol.38 , pp. 1239-1241
    • Seal, S.1    Thompson, D.2    Renwick, A.3
  • 28
    • 33745225487 scopus 로고    scopus 로고
    • Germline mutations 657del5 of the NBS1 gene contribute significantly to the incidence of breast cancer in Central Poland
    • 2
    • J Steffen D Nowakowska A Niwinska 2006 Germline mutations 657del5 of the NBS1 gene contribute significantly to the incidence of breast cancer in Central Poland Int J Cancer 119 2 472 475
    • (2006) Int J Cancer , vol.119 , pp. 472-475
    • Steffen, J.1    Nowakowska, D.2    Niwinska, A.3
  • 29
    • 16444384985 scopus 로고    scopus 로고
    • TGFbeta1/Smad3 counteracts BRCA1-dependent repair of DNA damage
    • 14
    • A Dubrovska T Kanamoto M Lomnytska 2005 TGFbeta1/Smad3 counteracts BRCA1-dependent repair of DNA damage Oncogene 24 14 2289 2297
    • (2005) Oncogene , vol.24 , pp. 2289-2297
    • Dubrovska, A.1    Kanamoto, T.2    Lomnytska, M.3
  • 30
    • 0037097982 scopus 로고    scopus 로고
    • JunB potentiates function of BRCA1 activation domain 1 (AD1) through a coiled-coil-mediated interaction
    • 12
    • YF Hu R Li 2002 JunB potentiates function of BRCA1 activation domain 1 (AD1) through a coiled-coil-mediated interaction Genes Dev 16 12 1509 1517
    • (2002) Genes Dev , vol.16 , pp. 1509-1517
    • Hu, Y.F.1    Li, R.2
  • 31
    • 0037104029 scopus 로고    scopus 로고
    • BRCA2 and Smad3 synergize in regulation of gene transcription
    • 36
    • O Preobrazhenska M Yakymovych T Kanamoto 2002 BRCA2 and Smad3 synergize in regulation of gene transcription Oncogene 21 36 5660 5664
    • (2002) Oncogene , vol.21 , pp. 5660-5664
    • Preobrazhenska, O.1    Yakymovych, M.2    Kanamoto, T.3
  • 32
    • 0036228955 scopus 로고    scopus 로고
    • Nucleotide exchange factor GEF-H1 mediates cross-talk between microtubules and the actin cytoskeleton
    • 4
    • M Krendel FT Zenke GM Bokoch 2002 Nucleotide exchange factor GEF-H1 mediates cross-talk between microtubules and the actin cytoskeleton Nat Cell Biol 4 4 294 301
    • (2002) Nat Cell Biol , vol.4 , pp. 294-301
    • Krendel, M.1    Zenke, F.T.2    Bokoch, G.M.3
  • 33
    • 0242509224 scopus 로고    scopus 로고
    • ROCK-generated contractility regulates breast epithelial cell differentiation in response to the physical properties of a three-dimensional collagen matrix
    • 3
    • MA Wozniak R Desai PA Solski 2003 ROCK-generated contractility regulates breast epithelial cell differentiation in response to the physical properties of a three-dimensional collagen matrix J Cell Biol 163 3 583 595
    • (2003) J Cell Biol , vol.163 , pp. 583-595
    • Wozniak, M.A.1    Desai, R.2    Solski, P.A.3
  • 34
    • 0032530501 scopus 로고    scopus 로고
    • Interleukin 4 inhibits growth and induces apoptosis in human breast cancer cells
    • 18
    • JL Gooch AV Lee D Yee 1998 Interleukin 4 inhibits growth and induces apoptosis in human breast cancer cells Cancer Res 58 18 4199 4205
    • (1998) Cancer Res , vol.58 , pp. 4199-4205
    • Gooch, J.L.1    Lee, A.V.2    Yee, D.3
  • 35
    • 33748092356 scopus 로고    scopus 로고
    • Interleukin gene polymorphisms and breast cancer: A case control study and systematic literature review
    • SP Balasubramanian IA Azmy SE Higham 2006 Interleukin gene polymorphisms and breast cancer: a case control study and systematic literature review BMC Cancer 6 188
    • (2006) BMC Cancer , vol.6 , pp. 188
    • Balasubramanian, S.P.1    Azmy, I.A.2    Higham, S.E.3
  • 36
    • 79959503826 scopus 로고    scopus 로고
    • The international HapMap project
    • 6968
    • TIH Consortium 2003 The international HapMap project Nature 426 6968 789 796
    • (2003) Nature , vol.426 , pp. 789-796
    • Consortium, T.I.H.1
  • 38
    • 0032880757 scopus 로고    scopus 로고
    • Is TP53 dysfunction required for BRCA1-associated carcinogenesis?
    • 1-2
    • M Schuyer EM Berns 1999 Is TP53 dysfunction required for BRCA1-associated carcinogenesis? Mol Cell Endocrinol 155 1-2 143 152
    • (1999) Mol Cell Endocrinol , vol.155 , pp. 143-152
    • Schuyer, M.1    Berns, E.M.2
  • 39
    • 0027429964 scopus 로고
    • A C-terminal protein-binding domain in the retinoblastoma protein regulates nuclear c-Abl tyrosine kinase in the cell cycle
    • 4
    • PJ Welch JY Wang 1993 A C-terminal protein-binding domain in the retinoblastoma protein regulates nuclear c-Abl tyrosine kinase in the cell cycle Cell 75 4 779 790
    • (1993) Cell , vol.75 , pp. 779-790
    • Welch, P.J.1    Wang, J.Y.2
  • 40
    • 33646084831 scopus 로고    scopus 로고
    • The circadian gene per1 plays an important role in cell growth and DNA damage control in human cancer cells
    • 3
    • S Gery N Komatsu L Baldjyan 2006 The circadian gene per1 plays an important role in cell growth and DNA damage control in human cancer cells Mol Cell 22 3 375 382
    • (2006) Mol Cell , vol.22 , pp. 375-382
    • Gery, S.1    Komatsu, N.2    Baldjyan, L.3
  • 41
    • 35448985252 scopus 로고    scopus 로고
    • Expression of the circadian clock genes Per1 and Per2 in sporadic and familial breast tumors
    • 10
    • SL Winter L Bosnoyan-Collins D Pinnaduwage 2007 Expression of the circadian clock genes Per1 and Per2 in sporadic and familial breast tumors Neoplasia 9 10 797 800
    • (2007) Neoplasia , vol.9 , pp. 797-800
    • Winter, S.L.1    Bosnoyan-Collins, L.2    Pinnaduwage, D.3


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