A novel cationic lipophosphoramide with diunsaturated lipid chains: Synthesis, physicochemical properties, and transfection activities

Journal of Medicinal Chemistry

Volumn 53, Issue 4, 2010, Pages 1496-1508

  Le Gall, Tony ^a,b   Loizeau, Damien ^c   Picquet, Erwan ^c   Carmoy, Nathalie ^a,b   Yaouanc, Jean Jacques ^a,b   Burel Deschamps, Laure ^c   Delépine, Pascal ^a,b   Giamarchi, Philippe ^c   Jaffrès, Paul Alain ^b,c   Lehn, Pierre ^a,b   Montier, Tristan ^a,b  

^a INSERM   (France)

^b CS 51819   (France)

^c UNIVERSITÉ DE BRETAGNE OCCIDENTALE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ARSONIC ACID DERIVATIVE; DILINOLEYLPHOSPHATIDYL 2 AMINOETHYLTRIMETHYLARSONIUM IODIDE; KLN 47; LINOLEIC ACID; LIPOPLEX; LIPOSOME; O,O DILINOLEYL N (2 BROMOETHYL)PHOSPHORAMIDATE; O,O DILINOLEYL N (2 IODOETHYL)PHOSPHORAMIDATE; PHOSPHORAMIDIC ACID DERIVATIVE; POLYUNSATURATED FATTY ACID; UNCLASSIFIED DRUG; UNSATURATED FATTY ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG DESIGN; DRUG DISTRIBUTION; DRUG SYNTHESIS; FEMALE; GENE DELIVERY SYSTEM; GENE VECTOR; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO GENE TRANSFER; IN VITRO STUDY; IN VIVO GENE TRANSFER; LUNG FIBROSIS; MOUSE; NONHUMAN; PHYSICAL CHEMISTRY;

EID: 77649201549     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm900897a     Document Type: Article

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