Fluorescence study of lipid-based DNA carriers properties: influence of cationic lipid chemical structure

Journal of Fluorescence

Volumn 18, Issue 5, 2008, Pages 835-841

  Burel Deschamps, Laure ^a   Mével, Mathieu ^a   Loizeau, Damien ^a   Ayadi, Farouk ^a   Yaouanc, Jean Jacques ^a   Clément, Jean Claude ^a   Jaffrès, Paul Alain ^a   Giamarchi, Philippe ^a  

^a UNIVERSITÉ DE BRETAGNE OCCIDENTALE   (France)

Author keywords

Anisotropy; Cationic phospholipids; Fluorescence; FRET; Liposomes

Indexed keywords

CATIONIC PHOSPHOLIPIDS; FRET; LIPID CHAINS; LIPOPLEX;

ANISOTROPY; CHEMICAL PROPERTIES; DNA; ENERGY TRANSFER; FLUORESCENCE; GENES; LIGHT EMISSION; LIPIDS; LIPOSOMES; LUMINESCENCE; NUCLEIC ACIDS; ORGANIC ACIDS;

PHOSPHOLIPIDS;

CATION; DNA; DRUG CARRIER; FLUORESCENT DYE; LIPID; LIPOSOME; PHOSPHOLIPID; RHODAMINE;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; FLUORESCENCE; FLUORESCENCE POLARIZATION; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENE TRANSFER; GENE VECTOR; GENETICS; METABOLISM; PHYSICAL CHEMISTRY; SPECTROFLUOROMETRY; VISCOSITY;

CATIONS; CHEMISTRY, PHYSICAL; DNA; DRUG CARRIERS; FLUORESCENCE; FLUORESCENCE POLARIZATION; FLUORESCENCE RESONANCE ENERGY TRANSFER; FLUORESCENT DYES; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; LIPIDS; LIPOSOMES; MOLECULAR STRUCTURE; PHOSPHOLIPIDS; RHODAMINES; SPECTROMETRY, FLUORESCENCE; VISCOSITY;

EID: 51649086194     PISSN: 10530509     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10895-008-0312-7     Document Type: Article

References (15)

1. Martin B, Aissaoui A, Sainlos M, Oudrhiri N, Hauchecorne M, Vigneron JP, Lehn JM, Lehn P (2003) Advances in cationic lipid-mediated gene delivery. Gene. Ther. Mol. Biol. 7:273-289
2. Martin B, Sainlos M, Aissaoui A, Oudrhiri N, Hauchecorne M, Vigneron JP, Lehn JM, Lehn P (2005) The design of cationic lipids for gene delivery. Curr. Pharm. Des. 11:375-394
3. Miller AD (1998) Cationic liposomes for gene therapy. Angew. Chem. Int. Ed. 37:1768-1785
4. Lehn P, Fabrega S, Oudrhiri N, Navarro J (1998) Gene delivery systems: bridging the gap between recombinant viruses and artificial vectors. Adv. Drug Deliv. Rev. 30:5-11
5. Guenin E, Herve AC, Floch VV, Loisel S, Yaouanc JJ, Clement JC, Ferec C, des Abbayes H (2000) Cationic phosphonolipids containing quaternary phosphonium and arsonium groups for DNA transfection with good efficiency and low cellular toxicity. Angew. Chem. Int. Ed. Engl. 39:629-631
6. Lamarche F, Mével M, Montier T, Burel-Deschamps L, Giamarchi P, Tripier R, Le Gall T, Cartier D, Lehn P, Clément JC, Jaffrès PA (2007) Lipophosphoramidates as lipidic part of lipospermines for gene delivery. Bioconjug. Chem. 18:1575-1582
7. Mével M, Montier T, Lamarche F, Delépine P, Le Gall T, Yaouanc JJ, Jaffrès PA, Cartier D, Lehn P, Clément JC (2007) Dicationic lipophosphoramidates as DNA carriers. Bioconjug. Chem. 18:1604-1611
8. Koumbi D, Clément JC, Sideratou Z, Yaouanc JJ, Loukopoulos D, Kollia P (2006) Factors mediating lipofection potency of a series of cationic phosphonolipids in human cell lines. Biochim. Biophys. Acta. 1760:1151-1159
9. Montier T, Delépine P, Le Ny K, Fichou Y, Le Bris M, Hardy E, Picquet E, Clément JC, Yaouanc JJ, Férec C (2004) KLN-5: a safe monocationic lipophosphoramide to transfect efficiently haematopoietic cell lines and human CD34+ cells. Biochim. Biophys. Acta. 1665:118-133
10. Picquet E, Le Ny K, Delepine P, Montier T, Yaouanc JJ, Cartier D, des Abbayes H, Ferec C, Clement JC (2005) Cationic lipophosphoramidates and lipophosphoguanidines are very efficient for in vivo DNA delivery. Bioconjug. Chem. 16:1051-1053
11. Valeur B (2002) Molecular fluorescence: principles and applications. Wiley, Weinheim
12. Struck DK, Hoeckstra D, Pagano RE (1981) Use of resonance energy transfer to monitor membrane fusion. Biochemistry 20:4093-4099
13. Mével M, Breuzard G, Yaouanc JJ, Clément JC, Lhen P, Pichon C, Jaffrès PA, Midoux P: Synthesis and gene delivery evaluation of new cationic phosphoramidate lipids: high efficiency of an imidazolium derivative. Chem Bio Chem (2008, in press)
14. Christiansson A, Wieslander A (1978) Membrane lipid metabolism in Acholeplasma laidlawii A EF 22. Eur. J. Biochem. 85:65-76
15. Regelin AE, Fankhaenel S, Gurtesch L, Prinz C, Von Kiedrowski G, Massing U (2000) Biophysical and lipofection studies of DOTAP analogs. Biochim. Biophys. Acta. (BBA)-Biomembranes 1464:151-164