Crystal structures of an oligopeptide-binding protein from the biosynthetic pathway of the β-lactamase inhibitor clavulanic acid

Journal of Molecular Biology

Volumn 396, Issue 2, 2010, Pages 332-344

  Mackenzie, Alasdair K ^a   Valegård, Karin ^a   Iqbal, Aman ^b   Caines, Matthew E C ^b   Kershaw, Nadia J ^b   Jensen, Susan E ^c   Schofield, Christopher J ^b   Andersson, Inger ^a  

^a SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Clavulanic acid; Oligopeptide binding proteins; Solute binding proteins; lactam; lactamase inhibitor

Indexed keywords

ALDEHYDE DERIVATIVE; ARGININE; BETA LACTAMASE INHIBITOR; BINDING PROTEIN; BRADYKININ; CLAVULANIC ACID; DIPEPTIDE DERIVATIVE; GLYCERALDEHYDE 3 PHOSPHATE; NONAPEPTIDE; OLIGOPEPTIDE; PROTEIN OPPA1; PROTEIN OPPA2; TRIPEPTIDE DERIVATIVE; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; BETA LACTAMASE; CARRIER PROTEIN; LIPOPROTEIN; OLIGOPEPTIDE BINDING PROTEIN, BACTERIA; OLIGOPEPTIDE-BINDING PROTEIN, BACTERIA;

ARTICLE; BINDING ASSAY; BIOSYNTHESIS; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE TRANSPORT; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG DECOMPOSITION; DRUG STRUCTURE; GENE CLUSTER; GENETIC CODE; NONHUMAN; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN STRUCTURE; PROTEIN TRANSPORT; STREPTOMYCES CLAVULIGERUS; STRUCTURE ANALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; ENZYME ACTIVE SITE; ENZYMOLOGY; METABOLISM; PHYSIOLOGY; PROTEIN CONFORMATION; STREPTOMYCES; X RAY CRYSTALLOGRAPHY;

STREPTOMYCES CLAVULIGERUS;

ARGININE; BACTERIAL PROTEINS; BETA-LACTAMASES; CARRIER PROTEINS; CATALYTIC DOMAIN; CLAVULANIC ACID; CRYSTALLOGRAPHY, X-RAY; LIPOPROTEINS; METABOLIC NETWORKS AND PATHWAYS; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION; STREPTOMYCES;

EID: 77449119599     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2009.11.045     Document Type: Article

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