Two Sets of Paralogous Genes Encode the Enzymes Involved in the Early Stages of Clavulanic Acid and Clavam Metabolite Biosynthesis in Streptomyces clavuligerus

Antimicrobial Agents and Chemotherapy

Volumn 48, Issue 3, 2004, Pages 930-939

  Tahlan, Kapil ^a   Park, Hyeon Ung ^a,b   Wong, Annie ^a   Beatty, Perrin H ^a   Jensen, Susan E ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA LACTAM SYNTHASE; CARBOXYETHYLARGININE SYNTHASE; CLAVAM; CLAVULANIC ACID; DRUG METABOLITE; DRUG METABOLIZING ENZYME; GLUTAMATE ACETYLTRANSFERASE; HYDROLASE; PROCALVAMINATE AMIDINOHYDROLASE; SYNTHETASE; UNCLASSIFIED DRUG;

ANTIBIOTIC BIOSYNTHESIS; ARGJ GENE; ARTICLE; BACTERIAL GENE; BACTERIUM MUTANT; BLS1 GENE; CEAS GENE; CEAS1 GENE; ENZYME DEFECT; GENE CLUSTER; GENE IDENTIFICATION; GENE ISOLATION; GENE LOCATION; NONHUMAN; NUCLEOTIDE SEQUENCE; OAT1 GENE; PAH 1 GENE; PARALOGY; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; SOUTHERN BLOTTING; STREPTOMYCES CLAVULIGERUS;

AMINO ACID SEQUENCE; ANTI-BACTERIAL AGENTS; BLOTTING, SOUTHERN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CLAVULANIC ACID; CLAVULANIC ACIDS; CULTURE MEDIA; DNA, BACTERIAL; FRAMESHIFT MUTATION; GENE EXPRESSION REGULATION, BACTERIAL; GENE TARGETING; MOLECULAR SEQUENCE DATA; MUTATION; PLASMIDS; STREPTOMYCES;

EID: 1442300124     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.48.3.930-939.2004     Document Type: Article

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