Oligomeric structure of proclavaminic acid amidino hydrolase: Evolution of a hydrolytic enzyme in clavulanic acid biosynthesis

Biochemical Journal

Volumn 366, Issue 2, 2002, Pages 423-434

  Elkins, Jonathan M ^a   Clifton, Ian J ^a   Hernández, Helena ^a   Doan, Linh X ^a   Robinson, Carol V ^a   Schofield, Christopher J ^a   Hewitson, Kirsty S ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Arginase; Manganese enzyme; Oligomerization

Indexed keywords

AMINO ACIDS; BACTERIA; BIOSYNTHESIS; HYDROLYSIS; METABOLISM; OLIGOMERS; POLYCYCLIC AROMATIC HYDROCARBONS; POSITIVE IONS; UREA;

HOMOLOGY;

ENZYMES;

ARGINASE; ARGININE; BETA LACTAM ANTIBIOTIC; CLAVULANIC ACID; COBALT; HYDROLASE; MANGANESE; ORNITHINE; UREA;

ARTICLE; BIOSYNTHESIS; CATALYSIS; CONFORMATION; CONTROLLED STUDY; DRUG STRUCTURE; ENZYME STRUCTURE; HYDROLYSIS; NONHUMAN; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; STREPTOMYCES CLAVULIGERUS;

AMINO ACID SEQUENCE; ARGININE; BACILLUS; BINDING SITES; CIRCULAR DICHROISM; CLAVULANIC ACID; CRYSTALLOGRAPHY, X-RAY; HYDROLYSIS; KINETICS; MACROMOLECULAR SUBSTANCES; MASS SPECTROMETRY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; UREOHYDROLASES;

BACTERIA (MICROORGANISMS); POSIBACTERIA; STREPTOMYCES; STREPTOMYCES CLAVULIGERUS;

EID: 0036712695     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20020125     Document Type: Article

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