The mechanism whereby heat shock induces apoptosis depends on the innate sensitivity of cells to stress

Cell Stress and Chaperones

Volumn 15, Issue 1, 2010, Pages 101-113

  Bellmann, Kerstin ^a   Charette, Steve J ^a,b   Nadeau, Philippe J ^a   Poirier, Dominic J ^a   Loranger, Anne ^a   Landry, Jacques ^a  

^a LAVAL UNIVERSITY   (Canada)

^b LAVAL UNIVERSITY   (Canada)

Author keywords

Aggresome; Apoptosis; Heat shock; Huntingtin; Nuclei morphology; Proteasome

Indexed keywords

HD PROTEIN, HUMAN; MYC PROTEIN; NERVE PROTEIN; NUCLEAR PROTEIN; PROTEASOME; PROTEIN BCL 2;

ANIMAL; APOPTOSIS; ARTICLE; CELL LINE; GENETIC TRANSFECTION; GENETICS; HEAT SHOCK RESPONSE; HUMAN; METABOLISM; RAT; SIGNAL TRANSDUCTION; TEMPERATURE;

ANIMALS; APOPTOSIS; CELL LINE; HEAT-SHOCK RESPONSE; HUMANS; MAP KINASE SIGNALING SYSTEM; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTO-ONCOGENE PROTEINS C-BCL-2; PROTO-ONCOGENE PROTEINS C-MYC; RATS; TEMPERATURE; TRANSFECTION;

EID: 77449113027     PISSN: 13558145     EISSN: 14661268     Source Type: Journal    
DOI: 10.1007/s12192-009-0126-9     Document Type: Article

References (38)

1. Auluck PK, Chan HY, Trojanowski JQ, Lee VM, Bonini NM (2002) Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease. Science 295:865-868 (Pubitemid 34118369)
2. Bailey CK, Andriola IF, Kampinga HH, Merry DE (2002) Molecular chaperones enhance the degradation of expanded polyglutamine repeat androgen receptor in a cellular model of spinal and bulbar muscular atrophy. Hum Mol Genet 11:515-523 (Pubitemid 34257488)
3. Bennett EJ, Bence NF, Jayakumar R, Kopito RR (2005) Global impairment of the ubiquitin-proteasome system by nuclear or cytoplasmic protein aggregates precedes inclusion body formation. Mol Cell 17:351-365 (Pubitemid 40193307)
4. Bredesen DE, Rao RV, Mehlen P (2006) Cell death in the nervous system. Nature 443:796-802 (Pubitemid 44622684)
5. Broers JL, Bronnenberg NM, Kuijpers HJ, Schutte B, Hutchison CJ, Ramaekers FC (2002) Partial cleavage of A-type lamins concurs with their total disintegration from the nuclear lamina during apoptosis. Eur J Cell Biol 81:677-691 (Pubitemid 36104763)
6. Bucciantini M, Giannoni E, Chiti F et al (2002) Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases. Nature 416:507-511 (Pubitemid 34288846)
7. Cao X, Bennett RL, May WS (2008) c-Myc and caspase-2 are involved in activating Bax during cytotoxic drug-induced apoptosis. J Biol Chem 283:14490-14496
8. Chang HY, Nishitoh H, Yang X, Ichijo H, Baltimore D (1998) Activation of apoptosis signal-regulating kinase 1 (ASK1) by the adapter protein Daxx. Science 281:1860-1863 (Pubitemid 28450508)
9. Charette SJ, Lavoie JN, Lambert H, Landry J (2000) Inhibition of Daxx-mediated apoptosis by heat shock protein 27. Mol Cell Biol 20:7602-7612
10. Cummings CJ, Sun Y, Opal P et al (2001) Over-expression of inducible HSP70 chaperone suppresses neuropathology and improves motor function in SCA1 mice. Hum Mol Genet 10:1511-1518 (Pubitemid 32684893)
11. Desbiens KM, Deschesnes RG, Labrie MM, Desfosses Y, Lambert H, Landry J, Bellmann K (2003) c-Myc potentiates the mitochondrial pathway of apoptosis by acting upstream of apoptosis signal-regulating kinase 1 (Ask1) in the p38 signalling cascade. Biochem J 372:631-641 (Pubitemid 36723910)
12. Evan GI, Wyllie AH, Gilbert CS et al (1992) Induction of apoptosis in fibroblasts by c-myc protein. Cell 69:119-128
13. Fortun J, Dunn WA Jr, Joy S, Li J, Notterpek L (2003) Emerging role for autophagy in the removal of aggresomes in Schwann cells. J Neurosci 23:10672-10680 (Pubitemid 37485281)
14. Friant S, Meier KD, Riezman H (2003) Increased ubiquitin-dependent degradation can replace the essential requirement for heat shock protein induction. EMBO J 22:3783-3791 (Pubitemid 36975707)
15. Gabai VL, Yaglom JA, Volloch V et al (2000) Hsp72-mediated suppression of c-Jun. N-terminal kinase is implicated in development of tolerance to caspase-independent cell death. Mol Cell Biol 20:6826-6836
16. Glover JR, Lindquist S (1998) Hsp104, Hsp70, and Hsp40: a novel chaperone system that rescues previously aggregated proteins. Cell 94:73-82 (Pubitemid 28347471)
17. Hohfeld J, Cyr DM, Patterson C (2001) From the cradle to the grave: molecular chaperones that may choose between folding and degradation. EMBO Rep 2:885-890 (Pubitemid 33040574)
18. Huot J, Houle F, Spitz DR, Landry J (1996) HSP27 phosphorylationmediated resistance against actin fragmentation and cell death induced by oxidative stress. Cancer Res 56:273-279 (Pubitemid 26026354)
19. Hut HM, Kampinga HH, Sibon OC (2005) Hsp70 protects mitotic cells against heat-induced centrosome damage and division abnormalities. Mol Biol Cell 16:3776-3785 (Pubitemid 41077086)
20. Johnston JA, Ward CL, Kopito RR (1998) Aggresomes: a cellular response to misfolded proteins. J Cell Biol 143:1883-1898 (Pubitemid 29022611)
21. Juin P, Hunt A, Littlewood T, Griffiths B, Swigart LB, Korsmeyer S, Evan G (2002) c-Myc functionally cooperates with Bax to induce apoptosis. Mol Cell Biol 22:6158-6169 (Pubitemid 34857836)
22. Kopito RR (2000) Aggresomes, inclusion bodies and protein aggregation. Trends Cell Biol 10:524-530
23. Kregel KC (2002) Heat shock proteins: modifying factors in physiological stress responses and acquired thermotolerance. J Appl Physiol 92:2177-2186 (Pubitemid 34666449)
24. Landry J, Chretien P, Lambert H, Hickey E, Weber LA (1989) Heat shock resistance conferred by expression of the human HSP27 gene in rodent cells. J Cell Biol 109:7-15 (Pubitemid 19180115)
25. Lindquist S (1986) The heat-shock response. Annu Rev Biochem 55:1151-1191 (Pubitemid 16070798)
26. Littlewood TD, Hancock DC, Danielian PS, Parker MG, Evan GI (1995) A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins. Nucleic Acids Res 23:1686-1690
27. Maulik N, Das DK (2008) Emerging potential of thioredoxin and thioredoxin interacting proteins in various disease conditions. Biochim Biophys Acta 1780:1368-1382
28. Michels AA, Kanon B, Konings AW, Bensaude O, Kampinga HH (2000) Cycloheximide-and puromycin-induced heat resistance: different effects on cytoplasmic and nuclear luciferases. Cell Stress Chaperones 5:181-187
29. Moir RD, Yoon M, Khuon S, Goldman RD (2000) Nuclear lamins A and B1: different pathways of assembly during nuclear envelope formation in living cells. J Cell Biol 151:1155-1168
30. Nadeau SI, Landry J (2007) Mechanisms of activation and regulation of the heat shock-sensitive signaling pathways. Adv Exp Med Biol 594:100-113
31. Perche PY, Vourc'h C, Konecny L, Souchier C, Robert-Nicoud M, Dimitrov S, Khochbin S (2000) Higher concentrations of histone macroH2A in the Barr body are correlated with higher nucleosome density. Curr Biol 10:1531-1534 (Pubitemid 32003647)
32. Salomons FA, Menendez-Benito V, Bottcher C, McCray BA, Taylor JP, Dantuma NP (2009) Selective accumulation of aggregationprone proteasome substrates in response to proteotoxic stress. Mol Cell Biol 29:1774-1785
33. Vidair CA, Doxsey SJ, Dewey WC (1993) Heat shock alters centrosome organization leading to mitotic dysfunction and cell death. J Cell Physiol 154:443-455 (Pubitemid 23076312)
34. Waelter S, Boeddrich A, Lurz R, Scherzinger E, Lueder G, Lehrach H, Wanker EE (2001) Accumulation of mutant huntingtin fragments in aggresome-like inclusion bodies as a result of insufficient protein degradation. Mol Biol Cell 12:1393-1407 (Pubitemid 33044419)
35. Ward CL, Omura S, Kopito RR (1995) Degradation of CFTR by the ubiquitin-proteasome pathway. Cell 83:121-127
36. Wigley WC, Fabunmi RP, Lee MG, Marino CR, Muallem S, De Martino GN, Thomas PJ (1999) Dynamic association of proteasomal machinery with the centrosome. J Cell Biol 145:481-490 (Pubitemid 29215713)
37. Wolter KG, Hsu YT, Smith CL, Nechushtan A, Xi XG, Youle RJ (1997) Movement of Bax from the cytosol to mitochondria during apoptosis. J Cell Biol 139:1281-1292 (Pubitemid 27523214)
38. Wyttenbach A, Carmichael J, Swartz J, Furlong RA, Narain Y, Rankin J, Rubinsztein DC (2000) Effects of heat shock, heat shock protein 40 (HDJ-2), and proteasome inhibition on protein aggregation in cellular models of Huntington's disease. Proc Natl Acad Sci U S A 97:2898-2903 (Pubitemid 30159269)