Transcutaneous electroporation mediated delivery of doxepin-HPCD complex: A sustained release approach for treatment of postherpetic neuralgia

Journal of Controlled Release

Volumn 142, Issue 3, 2010, Pages 361-367

  Sammeta, Srinivasa M ^a   Vaka, Siva Ram K ^a   Murthy, S Narasimha ^a  

^a UNIVERSITY OF MISSISSIPPI   (United States)

Author keywords

Doxepin; Electroporation; Hairless rats; Hydroxypropyl cyclodextrin; Sustained release

Indexed keywords

ANALGESIC EFFECT; CDS; COMPLEX SOLUTION; DOXEPIN; DRUG SOLUTIONS; ELECTROPORATION; INCLUSION COMPLEX; MECHANISTIC STUDIES; SUSTAINED RELEASE; TRANSCUTANEOUS; TRANSDERMAL DELIVERY;

DIFFERENTIAL SCANNING CALORIMETRY; RATS; STOICHIOMETRY;

DATA STORAGE EQUIPMENT;

2 HYDROXYPROPYL BETA CYCLODEXTRIN; DOXEPIN;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DISSOCIATION; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG SOLUTION; ELECTROPORATION; EPIDERMIS; HAIRLESS RAT; MALE; NONHUMAN; PERMEABILITY BARRIER; PHARMACODYNAMICS; POSTHERPETIC NEURALGIA; PRIORITY JOURNAL; RAT; STOICHIOMETRY; SUSTAINED DRUG RELEASE; SWINE;

ADMINISTRATION, CUTANEOUS; ANIMALS; ANTIDEPRESSIVE AGENTS, TRICYCLIC; BETA-CYCLODEXTRINS; DELAYED-ACTION PREPARATIONS; DOXEPIN; DRUG CARRIERS; ELECTROPORATION; EPIDERMIS; MEMBRANES, ARTIFICIAL; NEURALGIA, POSTHERPETIC; PERMEABILITY; RATS; RATS, HAIRLESS; SKIN ABSORPTION; SWINE;

EID: 77349126632     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2009.10.036     Document Type: Article

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