Doxepin by topical application and intrathecal route in rats

Anesthesia and Analgesia

Volumn 102, Issue 1, 2006, Pages 283-287

  Gerner, Peter ^a   Srinivasa, Venkatesh ^a   Zizza, Anthony M ^a   Zhuang, Zhi Ye ^a   Luo, ShiHua ^a   Zurakowski, David ^b   Eappen, Sunil ^a   Wang, GingKuo ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BUPIVACAINE; DOXEPIN; TRICYCLIC ANTIDEPRESSANT AGENT;

ANIMAL EXPERIMENT; ANTINOCICEPTION; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CONVALESCENCE; DRUG POTENCY; ERYTHEMA; LOCAL ANESTHESIA; MOTOR PERFORMANCE; NERVE BLOCK; NEUROTOXICITY; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; PROPRIOCEPTION; RAT; SCAR FORMATION; SCIATIC NERVE; WITHDRAWAL REFLEX;

EID: 29844440582     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/01.ane.0000183639.37428.4d     Document Type: Article

References (17)

1. Ayd FJ, Jr. Long-term treatment of chronic depression: 15-year experience with doxepin HC1. J Clin Psychiatry 1984;45:39-46.
2. Richeimer SH, Bajwa ZH, Kahraman SS, et al. Utilization patterns of tricyclic antidepressants in a multidisciplinary pain clinic: a survey. Clin J Pain 1997;13:324-9.
3. Edwards NB, Murphy JK, Downs AD, et al. Doxepin as an adjunct to smoking cessation: a double-blind pilot study. Am J Psychiatry 1989;146:373-6.
4. Greene SL, Reed CE, Schroeter AL. Double-blind crossover study comparing doxepin with diphenhydramine for the treatment of chronic urticaria. J Am Acad Dermatol 1985;12:669-75.
5. Epstein JB, Truelove EL, Oien H, et al. Oral topical doxepin rinse: analgesic effect in patients with oral mucosal pain due to cancer or cancer therapy. Oral Oncol 2001;37:632-7.
6. Wordliczek J, Banach M, Dorazil M, Przewlocka B. Influence of doxepin used in preemptive analgesia on the nociception in the perioperative period: experimental and clinical study. Pol J Pharmacol 2001;53:253-61.
7. Pancrazio JJ, Kamatchi GL, Roscoe AK, Lynch C, III. Inhibition of neuronal Na+ channels by antidepressant drugs. J Pharmacol Exp Ther 1998;284:208-14.
8. Sudoh Y, Cahoon EE, Gerner P, Wang GK. Tricyclic antidepressants as long-acting local anesthetics. Pain 2003;103:49-55.
9. Vohra J, Burrows G, Hunt D, Sloman G. The effect of toxic and therapeutic doses of tricyclic antidepressant drugs on intracardiac conduction. Eur J Cardiol 1975;3:219-27.
10. Kissin I, McDanal J, Xavier AV. Topical lidocaine for relief of superficial pain in postherpetic neuralgia. Neurology 1989;39:1132-3.
11. Haderer A, Gerner P, Kao G, et al. Cutaneous analgesia after transdermal application of amitriptyline versus lidocaine in rats. Anesth Analg 2003;96:1707-10.
12. Khan MA, Gerner P, Kuo WG. Amitriptyline for prolonged cutaneous analgesia in the rat. Anesthesiology 2002;96:109-16.
13. Storkson RV, Kjorsvik A, Tjolsen A, Hole K. Lumbar catheterization of the spinal subarachnoid space in the rat. J Neurosci Methods 1996;65:167-72.
14. Thalhammer JG, Vladimirova M, Bershadsky B, Strichartz GR. Neurologic evaluation of the rat during sciatic nerve block with lidocaine. Anesthesiology 1995;82:1013-25.
15. Wallenstein S, Zucker CL, Fleiss JL. Some statistical methods useful in circulation research. Circ Res 1980;47:1-9.
16. Epstein JB, Truelove EL, Oien H, et al., Oral topical doxepin rinse: analgesic effect in patients with oral mucosal pain due to cancer or cancer therapy. Oral Oncol 2001;37:632-7.
17. Lopachin RM, Rudy TA, Yaksh TL. An improved method for chronic catheterization of the rat spinal subarachnoid space. Physiol Behav 1981;27:559-61.