Transdermal delivery of fentanyl: Rapid onset of analgesia using skin electroporation

Journal of Controlled Release

Volumn 50, Issue 1-3, 1998, Pages 225-235

  Vanbever, Rita ^a   Langers, Gilles ^a   Montmayeur, Sonia ^a   Préat, Véronique ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

Fentanyl; In vivo; Iontophoresis; Skin electroporation; Transdermal drug delivery

Indexed keywords

FENTANYL;

ANALGESIA; ANIMAL EXPERIMENT; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG TOLERABILITY; ELECTROPORATION; ERYTHEMA; IONTOPHORESIS; MALE; NONHUMAN; PHARMACODYNAMICS; PRIORITY JOURNAL; RAT; SUBCUTANEOUS DRUG ADMINISTRATION; TRANSDERMAL DRUG ADMINISTRATION;

ADMINISTRATION, CUTANEOUS; ANALGESIA; ANALGESICS, OPIOID; ANIMALS; DRUG DELIVERY SYSTEMS; ELECTROPORATION; FENTANYL; MALE; RATS; SKIN;

EID: 0032472297     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(97)00147-8     Document Type: Article

References (34)

1. J. Hadgraft, R.H. Guy (Eds.), Transdermal Drug Delivery in Developmental Issues and Research Initiatives, Marcel Dekker, 1989.
2. Duthie D.J.R., Rowbotham D.J., Wyld R., Henderson P.D., Nimmo W.S. Plasma fentanyl concentrations during transdermal delivery of fentanyl to surgical patients. Br. J. Anaesth. 60:1988;614-618.
3. Varvel J.R., Shafer S.L., Hwang S.S., Coen P.A., Stanski D.R. Absorption characteristics of transdermally administered fentanyl. Anethesiology. 70:1989;928-934.
4. Roy S.D., Flynn G.L. Transdermal delivery of narcotic analgesics: pH, anatomical and subject influences on cutaneous permeability of fentanyl and sufentanil. Pharm. Res. 7:1990;842-847.
5. Lee L.Y., Lopez J.R. Transdermal fentanyl. Ann. Pharmacother. 26:1992;1393-1399.
6. Potenoy R.K., Southam M.A., Gupta S.K.et al. Transdermal fentanyl for cancer pain. Anesthesiology. 78:1993;36-43.
7. Thysman S., Préat V. In vivo iontophoresis of fentanyl and sufentanil in rats: pharmacokinetics and acute antinociceptive effects. Anesthesiology. 77:1993;61-66.
8. Thysman S., Tasset C., Préat V. Transdermal iontophoresis of fentanyl: delivery and mechanistic analysis. Int. J. Pharm. 101:1994;105-113.
9. Ashburn M.A., Streisand J., Zhang J. The iontophoresis of fentanyl citrate in humans. Anesthesiology. 82:1995;1146-1153.
10. Streisand J.B., Varvel J.R., Stanski D.R.et al. Absorption and bioavailability of oral transmucosal fentanyl citrate. Anesthesiology. 75:1991;223-229.
11. Schelter N.L., Weisman S., Rosenblum M., Bernstein B., Conard P.L. The use of oral transmucosal fentanyl citrate for painful procedures in children. Pediatrics. 95:1995;335-339.
12. Vercauteren M., Boeckx E., Hanegreefs G., Noorduin H., Vanden Bussche G. Intranasal sufentanil for pre-operative sedation. Anesthesia. 43:1988;270-273.
13. Prausnitz M.R., Bose V.G., Langer R., Weaver J.C. Electroporation of mammalian skin: a mechanism to enhance transdermal drug delivery. Proc. Natl. Acad. Sci. USA. 90:1993;10504-10508.
14. Vanbever R., Lecouturier N., Préat V. Transdermal delivery of metoprolol by electroporation. Pharm. Res. 11:1994;1657-1662.
15. Bommannan D.B., Tamada J., Leung L., Potts R.O. Effect of electroporation on transdermal iontophoretic delivery of luteinizing hormone (LHRH) in vitro. Pharm. Res. 11:1994;1809-1814.
16. Pliquett U., Weaver J.C. Electroporation of human skin: simultaneous measurement of changes in the transport of two fluorescent molecules and the passive electrical properties. Bioelectrochem. Bioenerg. 39:1996;1-12.
17. Chizmadzhev Y.A., Zarnytsin V.G., Weaver J.C., Potts R.O. Mechanism of electroinduced ionic species transport through a multilamellar lipid system. Biophys. J. 68:1995;749-765.
18. Edwards D.A., Prausnitz M.R., Langer R., Weaver J.C. Analysis of enhanced transdermal transport by skin electroporation. J. Control. Release. 34:1995;211-221.
19. V. Préat, R. Vanbever, Transdermal drug delivery by electroporation, in: K.R. Brain, V.J. James, K.A. Walters (Eds.), Prediction of Percutaneous Penetration, 4b, Cardiff, 1995, pp. 26-29.
20. Vanbever R., Le Boulengé E., Préat V. Transdermal delivery of fentanyl by electroporation I. Influence of electrical factors. Pharm. Res. 13:1996;559-565.
21. Vanbever R., De Morre N., Préat V. Transdermal delivery of fentanyl by electroporation II. Mechanisms involved in drug transport. Pharm. Res. 13:1996;1359-1365.
22. 2-adrenoceptor agonist, the volume of injection, and the global pain state of the animal on the activity of epidural fentanyl. Acta Anaesth. Belg. 40:1989;247-261.
23. 2-adrenoceptor agonist in rats. Anesthesiology. 81:1994;677-688.
24. Buerkle H., Yaksh T.L. Continuous intrathecal administration of short-lasting μ opioids remifentanil and alfentanil in the rat. Anesthesiology. 84:1996;926-935.
25. Prausnitz M.R. The effects of electric current applied to the skin: a review for transdermal drug delivery. Adv. Drug Deliv. Rev. 18:1996;395-425.
26. Zewert T., Pliquett U., Langer R., Weaver J.C. Transdermal transport of DNA antisense oligonucleotides by electroporation. Biochem. Biophys. Acta. 212:1995;286-292.
27. Prausnitz M.R., Edelman E.R., Gimm J.A., Langer R., Weaver J.C. Transdermal delivery of heparin by skin electroporation. Biotechnology. 13:1995;1205-1209.
28. R. Vanbever, D. Fouchard, A. Jadoul, N. De Morre, V. Préat, J.-P. Marty, In vivo non-invasive evaluation of hairless rat skin after high-voltage pulse exposure. Skin Pharmacol. (in press).
29. Prausnitz M.R., Pliquett U., Langer R., Weaver J.C. Rapid temporal control of transdermal drug delivery by electroporation. Pharm. Res. 11:1994;1834-1837.
30. Poklis A. Fentanyl: a review for clinical and analytical toxicologists. J. Toxicol. Clin. Toxicol. 33:1995;439-447.
31. Hug C.C., Murphy M.R. Tissue redistribution of fentanyl and termination of its effects in rats. Anesthesiology. 55:1981;369-375.
32. Björkman S., Stanski D.R., Verotta D., Harashima H. Comparative tissue concentration profiles of fentanyl and sufentanil in humans predicted from tissue/blood partition data obtained in rats. Anesthesiology. 72:1990;865-873.
33. Riviere J.E., Monteiro-Riviere A.N., Rogers R.A., Bommannan D., Tamada J.A., Potts R.O. Pulsatile transdermal delivery of LHRH using electroporation: drug delivery and skin toxicology. J. Control. Release. 36:1995;229-233.
34. R. Vanbever, D. Skrypczak, A. Jadoul, V. Préat, Comparison of skin electroperturbations induced by iontophoresis and electroporation, in: K.R. Brain, V.J. James, K.A. Walters (Eds.), Prediction of Percutaneous Penetration, 4b, Cardiff, 1995, pp. 243-246.