메뉴 건너뛰기




Volumn 10, Issue , 2010, Pages

Rac1 and Cdc42 are regulators of HRasV12-transformation and angiogenic factors in human fibroblasts

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENIC FACTOR; GUANOSINE TRIPHOSPHATASE; H RAS PROTEIN; MUTANT PROTEIN; PROTEIN CDC42; RAC1 PROTEIN; TETRACYCLINE; UNCLASSIFIED DRUG; UROKINASE; VASCULOTROPIN; RAS PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; VASCULOTROPIN A;

EID: 77349116199     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-10-13     Document Type: Article
Times cited : (13)

References (55)
  • 1
    • 0023898932 scopus 로고
    • The Ras gene family and human carcinogenesis
    • Bos JL. The Ras gene family and human carcinogenesis. Mutat Res 1988, 195:255-271.
    • (1988) Mutat Res , vol.195 , pp. 255-271
    • Bos, J.L.1
  • 2
    • 0024376173 scopus 로고
    • Ras oncogenes in human cancer: A review
    • Bos JL. Ras oncogenes in human cancer: A review. Cancer Res 1989, 49:4682-4689.
    • (1989) Cancer Res , vol.49 , pp. 4682-4689
    • Bos, J.L.1
  • 3
    • 0036488510 scopus 로고    scopus 로고
    • RHO-GTPases and cancer
    • 10.1038/nrc725, 12635176
    • Sahai E, Marshall CJ. RHO-GTPases and cancer. Nat Rev Cancer 2002, 2:133-142. 10.1038/nrc725, 12635176.
    • (2002) Nat Rev Cancer , vol.2 , pp. 133-142
    • Sahai, E.1    Marshall, C.J.2
  • 4
    • 0028961293 scopus 로고
    • Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia
    • 10.1016/0092-8674(95)90370-4, 7536630
    • Nobes CD, Hall A. Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia. Cell 1995, 81:53-62. 10.1016/0092-8674(95)90370-4, 7536630.
    • (1995) Cell , vol.81 , pp. 53-62
    • Nobes, C.D.1    Hall, A.2
  • 5
    • 0026778133 scopus 로고
    • The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors
    • 10.1016/0092-8674(92)90163-7, 1643657
    • Ridley AJ, Hall A. The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors. Cell 1992, 70:389-399. 10.1016/0092-8674(92)90163-7, 1643657.
    • (1992) Cell , vol.70 , pp. 389-399
    • Ridley, A.J.1    Hall, A.2
  • 6
    • 0026654125 scopus 로고
    • The small GTP-binding protein rac regulates growth factor-induced membrane ruffling
    • 10.1016/0092-8674(92)90164-8, 1643658
    • Ridley AJ, Paterson HF, Johnston CL, Diekmann D, Hall A. The small GTP-binding protein rac regulates growth factor-induced membrane ruffling. Cell 1992, 70:401-410. 10.1016/0092-8674(92)90164-8, 1643658.
    • (1992) Cell , vol.70 , pp. 401-410
    • Ridley, A.J.1    Paterson, H.F.2    Johnston, C.L.3    Diekmann, D.4    Hall, A.5
  • 7
    • 0030968580 scopus 로고    scopus 로고
    • Rho GTPases and signalling networks
    • 10.1101/gad.11.18.2295, 9308960
    • Van Aelst L, D'Souza-Schorey C. Rho GTPases and signalling networks. Genes Dev 1997, 11:2295-2322. 10.1101/gad.11.18.2295, 9308960.
    • (1997) Genes Dev , vol.11 , pp. 2295-2322
    • Van Aelst, L.1    D'Souza-Schorey, C.2
  • 8
    • 0030992814 scopus 로고    scopus 로고
    • Cdc42 regulates anchorage-independent growth and is necessary for Ras transformation
    • 232198, 9154844
    • Qiu RG, Abo A, McCormick F, Symons M. Cdc42 regulates anchorage-independent growth and is necessary for Ras transformation. Mol Cell Biol 1997, 17:3449-3458. 232198, 9154844.
    • (1997) Mol Cell Biol , vol.17 , pp. 3449-3458
    • Qiu, R.G.1    Abo, A.2    McCormick, F.3    Symons, M.4
  • 9
    • 0028903247 scopus 로고
    • An essential role for Rac in Ras transformation
    • 10.1038/374457a0, 7700355
    • Qiu RG, Chen J, Kirn D, McCormick F, Symons M. An essential role for Rac in Ras transformation. Nature 1995, 374:457-459. 10.1038/374457a0, 7700355.
    • (1995) Nature , vol.374 , pp. 457-459
    • Qiu, R.G.1    Chen, J.2    Kirn, D.3    McCormick, F.4    Symons, M.5
  • 10
    • 0033551698 scopus 로고    scopus 로고
    • Specific contributions of the small GTPases Rho, Rac, and Cdc42 to Dbl transformation
    • 10.1074/jbc.274.33.23633, 10438546
    • Lin R, Cerione RA, Manor D. Specific contributions of the small GTPases Rho, Rac, and Cdc42 to Dbl transformation. J Biol Chem 1999, 274:23633-23641. 10.1074/jbc.274.33.23633, 10438546.
    • (1999) J Biol Chem , vol.274 , pp. 23633-23641
    • Lin, R.1    Cerione, R.A.2    Manor, D.3
  • 11
    • 4344646902 scopus 로고    scopus 로고
    • Species- and cell type-specific requirements for cellular transformation
    • 10.1016/j.ccr.2004.07.009, 15324700
    • Rangarajan A, Hong SJ, Gifford A, Weinberg RA. Species- and cell type-specific requirements for cellular transformation. Cancer Cell 2004, 6:171-183. 10.1016/j.ccr.2004.07.009, 15324700.
    • (2004) Cancer Cell , vol.6 , pp. 171-183
    • Rangarajan, A.1    Hong, S.J.2    Gifford, A.3    Weinberg, R.A.4
  • 12
    • 0026066232 scopus 로고
    • Characteristics of an infinite life span diploid human fibroblast cell strain and a near-diploid strain arising from a clone of cells expressing a transfected v-myc oncogene
    • 10.1016/0014-4827(91)90489-H, 1915659
    • Morgan TL, Yang DJ, Fry DG, Hurlin PJ, Kohler SK, Maher VM, McCormick JJ. Characteristics of an infinite life span diploid human fibroblast cell strain and a near-diploid strain arising from a clone of cells expressing a transfected v-myc oncogene. Exp Cell Res 1991, 197:125-136. 10.1016/0014-4827(91)90489-H, 1915659.
    • (1991) Exp Cell Res , vol.197 , pp. 125-136
    • Morgan, T.L.1    Yang, D.J.2    Fry, D.G.3    Hurlin, P.J.4    Kohler, S.K.5    Maher, V.M.6    McCormick, J.J.7
  • 13
    • 0023572270 scopus 로고
    • Morphological transformation, focus formation, and anchorage independence induced in diploid human fibroblasts by expression of a transfected H-ras oncogene
    • Hurlin PJ, Fry DG, Maher VM, McCormick JJ. Morphological transformation, focus formation, and anchorage independence induced in diploid human fibroblasts by expression of a transfected H-ras oncogene. Cancer Res 1987, 47:5752-5757.
    • (1987) Cancer Res , vol.47 , pp. 5752-5757
    • Hurlin, P.J.1    Fry, D.G.2    Maher, V.M.3    McCormick, J.J.4
  • 14
    • 0023927992 scopus 로고
    • Transformation of diploid human fibroblasts by transfection with the v-sis, PDGF2/c-sis, or T24 H-ras genes
    • Fry DG, Hurlin PJ, Maher VM, McCormick JJ. Transformation of diploid human fibroblasts by transfection with the v-sis, PDGF2/c-sis, or T24 H-ras genes. Mutat Res 1988, 199:341-351.
    • (1988) Mutat Res , vol.199 , pp. 341-351
    • Fry, D.G.1    Hurlin, P.J.2    Maher, V.M.3    McCormick, J.J.4
  • 15
    • 0024548165 scopus 로고
    • Malignant transformation of human fibroblasts caused by expression of a transfected T24 HRAS oncogene
    • 10.1073/pnas.86.1.187, 286429, 2643097
    • Hurlin PJ, Maher VM, McCormick JJ. Malignant transformation of human fibroblasts caused by expression of a transfected T24 HRAS oncogene. Proc Natl Acad Sci USA 1989, 86:187-191. 10.1073/pnas.86.1.187, 286429, 2643097.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 187-191
    • Hurlin, P.J.1    Maher, V.M.2    McCormick, J.J.3
  • 17
    • 0025040839 scopus 로고
    • Malignant transformation of an infinite life span human fibroblast cell strain by transfection with v-Ki-ras
    • Fry DG, Milam LD, Dillberger JE, Maher VM, McCormick JJ. Malignant transformation of an infinite life span human fibroblast cell strain by transfection with v-Ki-ras. Oncogene 1990, 5:1415-1418.
    • (1990) Oncogene , vol.5 , pp. 1415-1418
    • Fry, D.G.1    Milam, L.D.2    Dillberger, J.E.3    Maher, V.M.4    McCormick, J.J.5
  • 18
    • 0025844741 scopus 로고
    • Malignant transformation of human fibroblasts correlates with increased activity of receptor-bound plasminogen activator
    • Jankun J, Maher VM, McCormick JJ. Malignant transformation of human fibroblasts correlates with increased activity of receptor-bound plasminogen activator. Cancer Res 1991, 51:1221-1226.
    • (1991) Cancer Res , vol.51 , pp. 1221-1226
    • Jankun, J.1    Maher, V.M.2    McCormick, J.J.3
  • 19
    • 67649600825 scopus 로고    scopus 로고
    • K-Ras promotes angiogenesis mediated by immortalized human pancreatic epithelial cells through mitogen-activated protein kinase signalling pathways
    • 10.1158/1541-7786.MCR-08-0577, 19509115
    • Matsuo Y, Campbell PM, Brekken RA, Sung B, Ouellette MM, Fleming JB, Aggarwal BB, Der CJ, Guha S. K-Ras promotes angiogenesis mediated by immortalized human pancreatic epithelial cells through mitogen-activated protein kinase signalling pathways. Mol Cancer Res 2009, 7:799-808. 10.1158/1541-7786.MCR-08-0577, 19509115.
    • (2009) Mol Cancer Res , vol.7 , pp. 799-808
    • Matsuo, Y.1    Campbell, P.M.2    Brekken, R.A.3    Sung, B.4    Ouellette, M.M.5    Fleming, J.B.6    Aggarwal, B.B.7    Der, C.J.8    Guha, S.9
  • 20
    • 0035877728 scopus 로고    scopus 로고
    • Rac1 activity is required for the activation of hypoxia-inducible factor 1
    • 10.1074/jbc.M100677200, 11283021
    • Hirota K, Semenza GL. Rac1 activity is required for the activation of hypoxia-inducible factor 1. J Biol Chem 2001, 276:21166-21172. 10.1074/jbc.M100677200, 11283021.
    • (2001) J Biol Chem , vol.276 , pp. 21166-21172
    • Hirota, K.1    Semenza, G.L.2
  • 21
    • 33646395416 scopus 로고    scopus 로고
    • Role of Rac1 and Cdc42 in hypoxia induced p53 and von Hippel-Lindau suppression and HIF1alpha activation
    • 10.1002/ijc.21763, 16395716
    • Xue Y, Bi F, Zhang X, Zhang S, Pan Y, Liu N, Shi Y, Yao X, Zheng Y, Fan D. Role of Rac1 and Cdc42 in hypoxia induced p53 and von Hippel-Lindau suppression and HIF1alpha activation. Int J Cancer 2006, 118:2965-2972. 10.1002/ijc.21763, 16395716.
    • (2006) Int J Cancer , vol.118 , pp. 2965-2972
    • Xue, Y.1    Bi, F.2    Zhang, X.3    Zhang, S.4    Pan, Y.5    Liu, N.6    Shi, Y.7    Yao, X.8    Zheng, Y.9    Fan, D.10
  • 22
    • 0028800305 scopus 로고
    • Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation
    • 230895, 7565796
    • Khosravi-Far R, Solski PA, Clark GJ, Kinch MS, Der CJ. Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation. Mol Cell Biol 1995, 15:6443-6453. 230895, 7565796.
    • (1995) Mol Cell Biol , vol.15 , pp. 6443-6453
    • Khosravi-Far, R.1    Solski, P.A.2    Clark, G.J.3    Kinch, M.S.4    Der, C.J.5
  • 23
    • 27944479854 scopus 로고    scopus 로고
    • Rho GTPases: biochemistry and biology
    • 10.1146/annurev.cellbio.21.020604.150721, 16212495
    • Jaffe AB, Hall A. Rho GTPases: biochemistry and biology. Annu Rev Cell Dev Biol 2005, 21:247-269. 10.1146/annurev.cellbio.21.020604.150721, 16212495.
    • (2005) Annu Rev Cell Dev Biol , vol.21 , pp. 247-269
    • Jaffe, A.B.1    Hall, A.2
  • 25
    • 33846273089 scopus 로고    scopus 로고
    • The Ras-MAPK pathway downregulates Caveolin-1 in rodent fibroblast but not in human fibroblasts: implications in the resistance to oncogene-mediated transformation
    • 10.1038/sj.onc.1209792, 16832346
    • Sasai K, Kakumoto K, Hanafusa H, Akagi T. The Ras-MAPK pathway downregulates Caveolin-1 in rodent fibroblast but not in human fibroblasts: implications in the resistance to oncogene-mediated transformation. Oncogene 2007, 26:449-455. 10.1038/sj.onc.1209792, 16832346.
    • (2007) Oncogene , vol.26 , pp. 449-455
    • Sasai, K.1    Kakumoto, K.2    Hanafusa, H.3    Akagi, T.4
  • 26
    • 0034077529 scopus 로고    scopus 로고
    • Regulation of cyclooxygenase 2 mRNA stability by the mitogen-activated protein kinase p38 signalling cascade
    • 10.1128/MCB.20.12.4265-4274.2000, 85794, 10825190
    • Lasa M, Mahtani KR, Finch A, Brewer G, Saklatvala J, Clark AR. Regulation of cyclooxygenase 2 mRNA stability by the mitogen-activated protein kinase p38 signalling cascade. Mol Cell Biol 2000, 20:4265-4274. 10.1128/MCB.20.12.4265-4274.2000, 85794, 10825190.
    • (2000) Mol Cell Biol , vol.20 , pp. 4265-4274
    • Lasa, M.1    Mahtani, K.R.2    Finch, A.3    Brewer, G.4    Saklatvala, J.5    Clark, A.R.6
  • 27
    • 0034714265 scopus 로고    scopus 로고
    • Stress-activated protein kinases (JNK and p38/HOG) are essential for vascular endothelial growth factor mRNA stability
    • 10.1074/jbc.M002104200, 10849421
    • Pages G, Berra E, Milanini J, Levy AP, Pouyssegur J. Stress-activated protein kinases (JNK and p38/HOG) are essential for vascular endothelial growth factor mRNA stability. J Biol Chem 2000, 275:26484-26491. 10.1074/jbc.M002104200, 10849421.
    • (2000) J Biol Chem , vol.275 , pp. 26484-26491
    • Pages, G.1    Berra, E.2    Milanini, J.3    Levy, A.P.4    Pouyssegur, J.5
  • 28
    • 0030734520 scopus 로고    scopus 로고
    • Cooperation of two PEA3/AP1 sites in uPA gene induction by TPA and FGF-2
    • 10.1016/S0378-1119(97)00445-9, 9409785
    • D'Orazio D, Besser D, Marksitzer R, Kunz C, Hume DA, Kiefer B, Nagamine Y. Cooperation of two PEA3/AP1 sites in uPA gene induction by TPA and FGF-2. Gene 1997, 201:179-187. 10.1016/S0378-1119(97)00445-9, 9409785.
    • (1997) Gene , vol.201 , pp. 179-187
    • D'Orazio, D.1    Besser, D.2    Marksitzer, R.3    Kunz, C.4    Hume, D.A.5    Kiefer, B.6    Nagamine, Y.7
  • 29
    • 33846345880 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase/Akt regulates the balance between plasminogen activator inhibitor-1 and urokinase to promote migration of SKOV-3 ovarian cancer cells
    • 10.1016/j.ygyno.2006.08.048, 17070899
    • Whitley BR, Beaulieu LM, Carter JC, Church FC. Phosphatidylinositol 3-kinase/Akt regulates the balance between plasminogen activator inhibitor-1 and urokinase to promote migration of SKOV-3 ovarian cancer cells. Gynecol Oncol 2007, 104:470-479. 10.1016/j.ygyno.2006.08.048, 17070899.
    • (2007) Gynecol Oncol , vol.104 , pp. 470-479
    • Whitley, B.R.1    Beaulieu, L.M.2    Carter, J.C.3    Church, F.C.4
  • 30
    • 0009374793 scopus 로고    scopus 로고
    • RalA requirement for v-Src- and v-Ras-induced tumorigenicity and overproduction of urokinase-type plasminogen activator: involvement of metalloproteases
    • 10.1038/sj.onc.1202850, 10467419
    • Aguirre-Ghiso JA, Frankel P, Farias EF, Lu Z, Jiang H, Olsen A, Feig LA, de Kier Joffe EB, Foster DA. RalA requirement for v-Src- and v-Ras-induced tumorigenicity and overproduction of urokinase-type plasminogen activator: involvement of metalloproteases. Oncogene 1999, 18:4718-4725. 10.1038/sj.onc.1202850, 10467419.
    • (1999) Oncogene , vol.18 , pp. 4718-4725
    • Aguirre-Ghiso, J.A.1    Frankel, P.2    Farias, E.F.3    Lu, Z.4    Jiang, H.5    Olsen, A.6    Feig, L.A.7    de Kier Joffe, E.B.8    Foster, D.A.9
  • 31
    • 0036782278 scopus 로고    scopus 로고
    • VEGF and the quest for tumour angiogenesis factors
    • 10.1038/nrc909, 12360282
    • Ferrara N. VEGF and the quest for tumour angiogenesis factors. Nat Rev Cancer 2002, 2:795-803. 10.1038/nrc909, 12360282.
    • (2002) Nat Rev Cancer , vol.2 , pp. 795-803
    • Ferrara, N.1
  • 32
    • 0032541029 scopus 로고    scopus 로고
    • P42/p44 MAP kinase module plays a key role in the transcriptional regulation of the vascular endothelial growth factor gene in fibroblasts
    • 10.1074/jbc.273.29.18165, 9660776
    • Milanini J, Vinals F, Pouyssegur J, Pages G. p42/p44 MAP kinase module plays a key role in the transcriptional regulation of the vascular endothelial growth factor gene in fibroblasts. J Biol Chem 1998, 273:18165-18172. 10.1074/jbc.273.29.18165, 9660776.
    • (1998) J Biol Chem , vol.273 , pp. 18165-18172
    • Milanini, J.1    Vinals, F.2    Pouyssegur, J.3    Pages, G.4
  • 33
    • 0037036451 scopus 로고    scopus 로고
    • Identification of two Sp1 phosphorylation sites for p42/p44 mitogen-activated protein kinases: their implication in vascular endothelial growth factor gene transcription
    • 10.1074/jbc.M201753200, 11904305
    • Milanini-Mongiat J, Pouyssegur J, Pages G. Identification of two Sp1 phosphorylation sites for p42/p44 mitogen-activated protein kinases: their implication in vascular endothelial growth factor gene transcription. J Biol Chem 2002, 277:20631-20639. 10.1074/jbc.M201753200, 11904305.
    • (2002) J Biol Chem , vol.277 , pp. 20631-20639
    • Milanini-Mongiat, J.1    Pouyssegur, J.2    Pages, G.3
  • 34
    • 33646540142 scopus 로고    scopus 로고
    • C-Jun kinase mediates expression of VEGF induced at transcriptional level by Rac1 and Cdc42Hs but not by RhoA
    • 10.1002/jcb.20801, 16440308
    • Saniger ML, Oya R, Macias D, Dominguez JN, Aranega A, Luque F. c-Jun kinase mediates expression of VEGF induced at transcriptional level by Rac1 and Cdc42Hs but not by RhoA. J Cell Biochem 2006, 98:650-660. 10.1002/jcb.20801, 16440308.
    • (2006) J Cell Biochem , vol.98 , pp. 650-660
    • Saniger, M.L.1    Oya, R.2    Macias, D.3    Dominguez, J.N.4    Aranega, A.5    Luque, F.6
  • 35
    • 13444267281 scopus 로고    scopus 로고
    • Down-regulation of overexpressed sp1 protein in human fibrosarcoma cell lines inhibits tumor formation
    • Lou Z, O'Reilly S, Liang H, Maher VM, Sleight SD, McCormick JJ. Down-regulation of overexpressed sp1 protein in human fibrosarcoma cell lines inhibits tumor formation. Cancer Res 2005, 65:1007-1017.
    • (2005) Cancer Res , vol.65 , pp. 1007-1017
    • Lou, Z.1    O'Reilly, S.2    Liang, H.3    Maher, V.M.4    Sleight, S.D.5    McCormick, J.J.6
  • 36
    • 43649093915 scopus 로고    scopus 로고
    • Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway
    • 10.1016/j.molcel.2008.04.009, 18498744
    • Kaelin WG, Ratcliffe PJ. Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway. Mol Cell 2008, 30:393-402. 10.1016/j.molcel.2008.04.009, 18498744.
    • (2008) Mol Cell , vol.30 , pp. 393-402
    • Kaelin, W.G.1    Ratcliffe, P.J.2
  • 37
    • 0033584464 scopus 로고    scopus 로고
    • Distinct expression patterns and transforming properties of multiple isoforms of Ost, an exchange factor for RhoA and Cdc42
    • 10.1038/sj.onc.1202851, 10467422
    • Lorenzi MV, Castagnino P, Chen Q, Hori Y, Miki T. Distinct expression patterns and transforming properties of multiple isoforms of Ost, an exchange factor for RhoA and Cdc42. Oncogene 1999, 18:4742-4755. 10.1038/sj.onc.1202851, 10467422.
    • (1999) Oncogene , vol.18 , pp. 4742-4755
    • Lorenzi, M.V.1    Castagnino, P.2    Chen, Q.3    Hori, Y.4    Miki, T.5
  • 38
    • 0141426629 scopus 로고    scopus 로고
    • Activated Cdc42 sequesters c-Cbl and prevents EGF receptor degradation
    • 10.1016/S0092-8674(03)00688-3, 14505571
    • Wu WJ, Tu S, Cerione RA. Activated Cdc42 sequesters c-Cbl and prevents EGF receptor degradation. Cell 2003, 114:715-725. 10.1016/S0092-8674(03)00688-3, 14505571.
    • (2003) Cell , vol.114 , pp. 715-725
    • Wu, W.J.1    Tu, S.2    Cerione, R.A.3
  • 39
    • 1942532875 scopus 로고    scopus 로고
    • Mechanism of processing of the NF-kappa B2 p100 precursor: identification of the specific polyubiquitin chain-anchoring lysine residue and analysis of the role of NEDD8-modification on the SCF(beta-TrCP) ubiquitin ligase
    • 10.1038/sj.onc.1207366, 14676825
    • Amir RE, Haecker H, Karin M, Ciechanover A. Mechanism of processing of the NF-kappa B2 p100 precursor: identification of the specific polyubiquitin chain-anchoring lysine residue and analysis of the role of NEDD8-modification on the SCF(beta-TrCP) ubiquitin ligase. Oncogene 2004, 23:2540-2547. 10.1038/sj.onc.1207366, 14676825.
    • (2004) Oncogene , vol.23 , pp. 2540-2547
    • Amir, R.E.1    Haecker, H.2    Karin, M.3    Ciechanover, A.4
  • 40
    • 26844440904 scopus 로고    scopus 로고
    • Translation elongation factor eEF1A2 is a potential oncoprotein that is overexpressed in two-thirds of breast tumours
    • 10.1186/1471-2407-5-113, 1236916, 16156888
    • Tomlinson VA, Newbery HJ, Wray NR, Jackson J, Larionov A, Miller WR, Dixon JM, Abbott CM. Translation elongation factor eEF1A2 is a potential oncoprotein that is overexpressed in two-thirds of breast tumours. BMC Cancer 2005, 5:113. 10.1186/1471-2407-5-113, 1236916, 16156888.
    • (2005) BMC Cancer , vol.5 , pp. 113
    • Tomlinson, V.A.1    Newbery, H.J.2    Wray, N.R.3    Jackson, J.4    Larionov, A.5    Miller, W.R.6    Dixon, J.M.7    Abbott, C.M.8
  • 42
    • 0032733652 scopus 로고    scopus 로고
    • Differential gene expression in tumorigenic and nontumorigenic HeLa × normal human fibroblast hybrid cells
    • 10.1002/(SICI)1098-2744(199912)26:4<298::AID-MC8>3.0.CO;2-M, 10569806
    • Tsujimoto H, Nishizuka S, Redpath JL, Stanbridge EJ. Differential gene expression in tumorigenic and nontumorigenic HeLa × normal human fibroblast hybrid cells. Mol Carcinog 1999, 26:298-304. 10.1002/(SICI)1098-2744(199912)26:4<298::AID-MC8>3.0.CO;2-M, 10569806.
    • (1999) Mol Carcinog , vol.26 , pp. 298-304
    • Tsujimoto, H.1    Nishizuka, S.2    Redpath, J.L.3    Stanbridge, E.J.4
  • 43
    • 0034041606 scopus 로고    scopus 로고
    • Disordered expression of inhibitory receptors on the NK1-type natural killer (NK) leukaemic cells from patients with hypersensitivity to mosquito bites
    • 10.1046/j.1365-2249.2000.01253.x, 1905558, 10844517
    • Seo N, Tokura Y, Ishihara S, Takeoka Y, Tagawa S, Takigawa M. Disordered expression of inhibitory receptors on the NK1-type natural killer (NK) leukaemic cells from patients with hypersensitivity to mosquito bites. Clin Exp Immunol 2000, 120:413-419. 10.1046/j.1365-2249.2000.01253.x, 1905558, 10844517.
    • (2000) Clin Exp Immunol , vol.120 , pp. 413-419
    • Seo, N.1    Tokura, Y.2    Ishihara, S.3    Takeoka, Y.4    Tagawa, S.5    Takigawa, M.6
  • 44
    • 21744445069 scopus 로고    scopus 로고
    • Heat shock proteins in cancer: diagnostic, prognostic, predictive, and treatment implications
    • 10.1379/CSC-99r.1, 1176476, 16038406
    • Ciocca DR, Calderwood SK. Heat shock proteins in cancer: diagnostic, prognostic, predictive, and treatment implications. Cell Stress Chaperones 2005, 10:86-103. 10.1379/CSC-99r.1, 1176476, 16038406.
    • (2005) Cell Stress Chaperones , vol.10 , pp. 86-103
    • Ciocca, D.R.1    Calderwood, S.K.2
  • 45
    • 22144457035 scopus 로고    scopus 로고
    • Essential roles of IGFBP-3 and IGFBP-rP1 in breast cancer
    • 10.1016/j.ejca.2005.04.023, 15979304
    • Burger AM, Leyland-Jones B, Banerjee K, Spyropoulos DD, Seth AK. Essential roles of IGFBP-3 and IGFBP-rP1 in breast cancer. Eur J Cancer 2005, 41:1515-1527. 10.1016/j.ejca.2005.04.023, 15979304.
    • (2005) Eur J Cancer , vol.41 , pp. 1515-1527
    • Burger, A.M.1    Leyland-Jones, B.2    Banerjee, K.3    Spyropoulos, D.D.4    Seth, A.K.5
  • 46
    • 18444408375 scopus 로고    scopus 로고
    • COX-2: a molecular target for colorectal cancer prevention
    • 10.1200/JCO.2005.09.051, 15837998
    • Brown JR, DuBois RN. COX-2: a molecular target for colorectal cancer prevention. J Clin Oncol 2005, 23:2840-2855. 10.1200/JCO.2005.09.051, 15837998.
    • (2005) J Clin Oncol , vol.23 , pp. 2840-2855
    • Brown, J.R.1    DuBois, R.N.2
  • 47
    • 27944473690 scopus 로고    scopus 로고
    • VEGF as a key mediator of angiogenesis in cancer
    • 10.1159/000088478, 16301830
    • Carmeliet P. VEGF as a key mediator of angiogenesis in cancer. Oncology 2005, 69(Suppl 3):4-10. 10.1159/000088478, 16301830.
    • (2005) Oncology , vol.69 , Issue.SUPPL. 3 , pp. 4-10
    • Carmeliet, P.1
  • 48
    • 33847052927 scopus 로고    scopus 로고
    • Tumor-associated proteolytic factors uPA and PAI-1: critical appraisal of their clinical relevance in breast cancer and their integration into decision-support algorithms
    • 10.1080/10408360601040970, 17364692
    • Harbeck N, Schmitt M, Paepke S, Allgayer H, Kates RE. Tumor-associated proteolytic factors uPA and PAI-1: critical appraisal of their clinical relevance in breast cancer and their integration into decision-support algorithms. Crit Rev Clin Lab Sci 2007, 44:179-201. 10.1080/10408360601040970, 17364692.
    • (2007) Crit Rev Clin Lab Sci , vol.44 , pp. 179-201
    • Harbeck, N.1    Schmitt, M.2    Paepke, S.3    Allgayer, H.4    Kates, R.E.5
  • 54
    • 0035839425 scopus 로고    scopus 로고
    • Requirement for high mobility group protein HMGI-C interaction with STAT3 inhibitor PIAS3 in repression of alpha-subunit of epithelial Na+ channel (alpha-ENaC) transcription by Ras activation in salivary epithelial cells
    • 10.1074/jbc.M103153200, 11390395
    • Zentner MD, Lin HH, Deng HT, Kim KJ, Shih HM, Ann DK. Requirement for high mobility group protein HMGI-C interaction with STAT3 inhibitor PIAS3 in repression of alpha-subunit of epithelial Na+ channel (alpha-ENaC) transcription by Ras activation in salivary epithelial cells. J Biol Chem 2001, 276:29805-29814. 10.1074/jbc.M103153200, 11390395.
    • (2001) J Biol Chem , vol.276 , pp. 29805-29814
    • Zentner, M.D.1    Lin, H.H.2    Deng, H.T.3    Kim, K.J.4    Shih, H.M.5    Ann, D.K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.