Mechanism of processing of the NF-κB2 p100 precursor: Identification of the specific polyubiquitin chain-anchoring lysine residue and analysis of the role of NEDD8-modification on the SCFβ-TrCP ubiquitin ligase

Oncogene

Volumn 23, Issue 14, 2004, Pages 2540-2547

  Amir, Ruthie E ^a   Haecker, Hans ^b   Karin, Michael ^b   Ciechanover, Aaron ^a  

^a TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

NEDD8; NF B2; p100; p52; Processing; Ubiquitin

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LYSINE; POLYUBIQUITIN; PROTEIN P100; UBIQUITIN PROTEIN LIGASE; UBIQUITIN PROTEIN LIGASE NEDD8; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; EMBRYO; HUMAN; HUMAN CELL; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PURIFICATION; REGULATORY MECHANISM; RESIDUE ANALYSIS; UBIQUITINATION;

BACULOVIRIDAE; BETA-TRANSDUCIN REPEAT-CONTAINING PROTEINS; CELL CYCLE PROTEINS; CELL LINE; HELA CELLS; HUMANS; I-KAPPA B PROTEINS; LIGASES; LYSINE; MUTAGENESIS, SITE-DIRECTED; NF-KAPPA B; PHOSPHORYLATION; POINT MUTATION; PROTEIN PRECURSORS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; RNA, SMALL INTERFERING; UBIQUITINS;

EID: 1942532875     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1207366     Document Type: Article

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