Knockdown of integrin β4 in primary cultured mouse neurons blocks survival and induces apoptosis by elevating NADPH oxidase activity and reactive oxygen species level

International Journal of Biochemistry and Cell Biology

Volumn 40, Issue 4, 2008, Pages 689-699

  Lv, Xin ^a,b   Su, Le ^a,b   Yin, Deling ^c   Sun, Chunhui ^a,b   Zhao, Jing ^a,b   Zhang, Shangli ^a,b   Miao, Junying ^a,b  

^a SHANDONG UNIVERSITY   (China)

^b BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^c East Tennessee State University   (United States)

Author keywords

Apoptosis; Integrin 4; Primary culture neurons; Reactive oxygen species; RNA interference

Indexed keywords

BETA4 INTEGRIN; COPPER; MANGANESE SUPEROXIDE DISMUTASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SMALL INTERFERING RNA; SUPEROXIDE DISMUTASE; ZINC;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL CULTURE; CELL SURVIVAL; CELL VIABILITY; DOWN REGULATION; EMBRYO; ENZYME ACTIVITY; ENZYME INHIBITION; MOUSE; NERVE CELL; NERVE CELL NECROSIS; NONHUMAN; PROTEIN EXPRESSION; ANIMAL; BRAIN CORTEX; CYTOLOGY; GENETICS; IMMUNOHISTOCHEMISTRY; METABOLISM; NICK END LABELING; PHYSIOLOGY; RNA INTERFERENCE; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELL SURVIVAL; CELLS, CULTURED; CEREBRAL CORTEX; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; INTEGRIN BETA4; MICE; NADPH OXIDASE; NEURONS; REACTIVE OXYGEN SPECIES; RNA INTERFERENCE;

EID: 39649123986     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2007.10.006     Document Type: Article

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