Stability of low concentrations of guanine-based antivirals in sucrose or maltitol solutions

International Journal of Pharmaceutics

Volumn 342, Issue 1-2, 2007, Pages 87-94

  Desai, D ^a   Rao, V ^a   Guo, H ^a   Li, D ^a   Bolgar, M ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

Acyclovir; Entecavir; Lobucavir; Maltitol; Nucleophilic addition; pH effect; Stability; Sucrose

Indexed keywords

ACICLOVIR; ALDEHYDE; AMINE; ANTIVIRUS AGENT; CARBONYL DERIVATIVE; DISACCHARIDE; ENTECAVIR; FRUCTOSE; GLUCOSE; GUANINE; KETONE; LOBUCAVIR; MALTITOL; MONOSACCHARIDE; SUCROSE;

ARTICLE; DRUG DEGRADATION; DRUG STABILITY; HYDROLYSIS; PH MEASUREMENT; PRIORITY JOURNAL; TEMPERATURE SENSITIVITY;

ACYCLOVIR; ANTIVIRAL AGENTS; DRUG STABILITY; FRUCTOSE; GLUCOSE; GUANINE; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; MALTOSE; PHARMACEUTICAL SOLUTIONS; SOLUTIONS; SUCROSE; SUGAR ALCOHOLS; TEMPERATURE;

EID: 34547875780     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2007.05.025     Document Type: Article

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