Effect of pH, counter ion, and phosphate concentration on the glass transition temperature of freeze-dried sugar-phosphate mixtures

Pharmaceutical Research

Volumn 21, Issue 9, 2004, Pages 1615-1621

  Ohtake, Satoshi ^a   Schebor, Carolina ^b   Palecek, Sean P ^a   De Pablo, Juan J ^a  

^a University of Wisconsin Madison   (United States)

^b UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

Freeze drying; Glass transition, sucrose; Phosphate; Trehalose

Indexed keywords

HYDROXYL GROUP; PHOSPHATE; POTASSIUM DIHYDROGEN PHOSPHATE; SODIUM DIHYDROGEN PHOSPHATE; SUCROSE; TREHALOSE; WATER;

ACIDITY; ALKALINITY; ANALYTIC METHOD; ARTICLE; DIFFERENTIAL SCANNING CALORIMETRY; FREEZE DRYING; GLASS TRANSITION TEMPERATURE; INFRARED SPECTROSCOPY; MOLECULAR INTERACTION; PH; PRIORITY JOURNAL; TEMPERATURE DEPENDENCE; CHEMISTRY; TEMPERATURE; THERMODYNAMICS;

CALORIMETRY, DIFFERENTIAL SCANNING; FREEZE DRYING; HYDROGEN-ION CONCENTRATION; PHOSPHATES; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; SUCROSE; TEMPERATURE; THERMODYNAMICS; TREHALOSE; WATER;

EID: 21644451625     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:PHAM.0000041456.19377.87     Document Type: Article

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