메뉴 건너뛰기




Volumn 131, Issue 2, 2005, Pages 437-449

Effect of glutamine synthetase inhibition on astrocyte swelling and altered astroglial protein expression during hyperammonemia in rats

Author keywords

Ammonia; Astrocyte; Cerebral edema; Connexin; Glial fibrillary Acidic protein; Glutamine

Indexed keywords

ACETIC ACID; AMMONIUM ACETATE; CONNEXIN 43; GAP JUNCTION PROTEIN; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUTAMATE AMMONIA LIGASE; GLUTAMATE TRANSPORTER; METHIONINE SULFOXIMINE;

EID: 13544270851     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2004.10.045     Document Type: Article
Times cited : (72)

References (48)
  • 2
    • 0036096020 scopus 로고    scopus 로고
    • Loss of expression of glial fibrillary acidic protein in acute hyperammonemia
    • M. Belanger, P. Desjardins, N. Chatauret, R.F. Butterworth Loss of expression of glial fibrillary acidic protein in acute hyperammonemia Neurochem Int 41 2002 155 160
    • (2002) Neurochem Int , vol.41 , pp. 155-160
    • Belanger, M.1    Desjardins, P.2    Chatauret, N.3    Butterworth, R.F.4
  • 3
    • 84989509425 scopus 로고
    • Ammonia-induced brain edema and intracranial hypertension in rats after portacaval anastomosis
    • A.T. Blei, S. Olafsson, G. Therrien, R.F. Butterworth Ammonia-induced brain edema and intracranial hypertension in rats after portacaval anastomosis Hepatology 19 1994 1437 1444
    • (1994) Hepatology , vol.19 , pp. 1437-1444
    • Blei, A.T.1    Olafsson, S.2    Therrien, G.3    Butterworth, R.F.4
  • 4
    • 0036146912 scopus 로고    scopus 로고
    • Chronic inhibition of glutamine synthetase is not associated with impairment of learning and memory in mice
    • M. Blin, W.E. Crusio, T. Hevor, J.F. Cloix Chronic inhibition of glutamine synthetase is not associated with impairment of learning and memory in mice Brain Res Bull 57 2002 11 15
    • (2002) Brain Res Bull , vol.57 , pp. 11-15
    • Blin, M.1    Crusio, W.E.2    Hevor, T.3    Cloix, J.F.4
  • 7
    • 0041469937 scopus 로고    scopus 로고
    • Effects of hypothermia on brain glucose metabolism in acute liver failure: A H/C-nuclear magnetic resonance study
    • N. Chatauret, C. Zwingmann, C. Rose, D. Leibfritz, R.F. Butterworth Effects of hypothermia on brain glucose metabolism in acute liver failure a H/C-nuclear magnetic resonance study Gastroenterology 125 2003 815 824
    • (2003) Gastroenterology , vol.125 , pp. 815-824
    • Chatauret, N.1    Zwingmann, C.2    Rose, C.3    Leibfritz, D.4    Butterworth, R.F.5
  • 8
    • 0035181229 scopus 로고    scopus 로고
    • Role of glutamine in cerebral nitrogen metabolism and ammonia neurotoxicity
    • A.J.L. Cooper Role of glutamine in cerebral nitrogen metabolism and ammonia neurotoxicity Ment Retard Dev Disabil Res Rev 7 2001 280 286
    • (2001) Ment Retard Dev Disabil Res Rev , vol.7 , pp. 280-286
    • Cooper, A.J.L.1
  • 10
    • 0029827933 scopus 로고    scopus 로고
    • Glutamine, myo-inositol, and organic brain osmolytes after portocaval anastomosis in the rat: Implications for ammonia-induced brain edema
    • J. Cordoba, J. Gottstein, A.T. Blei Glutamine, myo-inositol, and organic brain osmolytes after portocaval anastomosis in the rat implications for ammonia-induced brain edema Hepatology 24 1996 919 923
    • (1996) Hepatology , vol.24 , pp. 919-923
    • Cordoba, J.1    Gottstein, J.2    Blei, A.T.3
  • 11
    • 0342314620 scopus 로고    scopus 로고
    • Effect of portacaval anastomosis on glutamine synthetase protein and gene expression in brain, liver and skeletal muscle
    • P. Desjardins, K.V. Rao, A. Michalak, C. Rose, R.F. Butterworth Effect of portacaval anastomosis on glutamine synthetase protein and gene expression in brain, liver and skeletal muscle Metab Brain Dis 14 1999 273 280
    • (1999) Metab Brain Dis , vol.14 , pp. 273-280
    • Desjardins, P.1    Rao, K.V.2    Michalak, A.3    Rose, C.4    Butterworth, R.F.5
  • 12
    • 0027474144 scopus 로고
    • Effect of reducing brain glutamine synthesis on metabolic symptoms of hepatic encephalopathy
    • R.A. Hawkins, J. Jessy, A.M. Mans, M.R. De Joseph Effect of reducing brain glutamine synthesis on metabolic symptoms of hepatic encephalopathy J Neurochem 60 1993 1000 1006
    • (1993) J Neurochem , vol.60 , pp. 1000-1006
    • Hawkins, R.A.1    Jessy, J.2    Mans, A.M.3    De Joseph, M.R.4
  • 14
    • 0032986418 scopus 로고    scopus 로고
    • Preserved hypocapnic pial arteriolar constriction during hyperammonemia by glutamine synthetase inhibition
    • T. Hirata, T. Kawaguchi, S.W. Brusilow, R.J. Traystman, R.C. Koehler Preserved hypocapnic pial arteriolar constriction during hyperammonemia by glutamine synthetase inhibition Am J Physiol 276 1999 H456 H463
    • (1999) Am J Physiol , vol.276
    • Hirata, T.1    Kawaguchi, T.2    Brusilow, S.W.3    Traystman, R.J.4    Koehler, R.C.5
  • 15
    • 0029975974 scopus 로고    scopus 로고
    • Impaired pial arteriolar reactivity to hypercapnia during hyperammonemia depends on glutamine synthesis
    • T. Hirata, R.C. Koehler, T. Kawaguchi, S.W. Brusilow, R.J. Traystman Impaired pial arteriolar reactivity to hypercapnia during hyperammonemia depends on glutamine synthesis Stroke 27 1996 729 736
    • (1996) Stroke , vol.27 , pp. 729-736
    • Hirata, T.1    Koehler, R.C.2    Kawaguchi, T.3    Brusilow, S.W.4    Traystman, R.J.5
  • 16
    • 2542491081 scopus 로고    scopus 로고
    • Glutamine-induced free radical production in cultured astrocytes
    • A.R. Jayakumar, K.V. Rama Rao, A. Schousboe, M.D. Norenberg Glutamine-induced free radical production in cultured astrocytes Glia 46 2004 296 301
    • (2004) Glia , vol.46 , pp. 296-301
    • Jayakumar, A.R.1    Rama Rao, K.V.2    Schousboe, A.3    Norenberg, M.D.4
  • 17
    • 0022595320 scopus 로고
    • Glial fibrillary acidic protein and S-100 protein in human hepatic encephalopathy: Immunocytochemical demonstration of dissociation of two glia-associated proteins
    • T. Kimura, H. Budka Glial fibrillary acidic protein and S-100 protein in human hepatic encephalopathy immunocytochemical demonstration of dissociation of two glia-associated proteins Acta Neuropathol (Berl) 70 1986 17 21
    • (1986) Acta Neuropathol (Berl) , vol.70 , pp. 17-21
    • Kimura, T.1    Budka, H.2
  • 18
    • 0030789808 scopus 로고    scopus 로고
    • Decreased glutamate transporter (GLT-1) expression in frontal cortex of rats with acute liver failure
    • K. Knecht, A. Michalak, C. Rose, J.D. Rothstein, R.F. Butterworth Decreased glutamate transporter (GLT-1) expression in frontal cortex of rats with acute liver failure Neurosci Lett 229 1997 201 203
    • (1997) Neurosci Lett , vol.229 , pp. 201-203
    • Knecht, K.1    Michalak, A.2    Rose, C.3    Rothstein, J.D.4    Butterworth, R.F.5
  • 19
    • 0026541298 scopus 로고
    • Metabolic disorders of the brain in chronic hepatic encephalopathy detected with H-1 MR spectroscopy
    • R. Kreis, B.D. Ross, N.A. Farrow, Z. Ackerman Metabolic disorders of the brain in chronic hepatic encephalopathy detected with H-1 MR spectroscopy Radiology 182 1992 19 27
    • (1992) Radiology , vol.182 , pp. 19-27
    • Kreis, R.1    Ross, B.D.2    Farrow, N.A.3    Ackerman, Z.4
  • 20
    • 0021967542 scopus 로고
    • Measurement of GFAP in hepatic encephalopathy by ELISA and transblots
    • H.A. Kretzschmar, S.J. DeArmond, L.S. Forno Measurement of GFAP in hepatic encephalopathy by ELISA and transblots J Neuropathol Exp Neurol 44 1985 459 471
    • (1985) J Neuropathol Exp Neurol , vol.44 , pp. 459-471
    • Kretzschmar, H.A.1    Dearmond, S.J.2    Forno, L.S.3
  • 21
    • 0014277351 scopus 로고
    • The duration of the inhibition of glutamine synthetase by methionine sulfoximine
    • C. Lamar Jr The duration of the inhibition of glutamine synthetase by methionine sulfoximine Biochem Pharmacol 17 1968 636 640
    • (1968) Biochem Pharmacol , vol.17 , pp. 636-640
    • Lamar, C.1    Jr2
  • 22
    • 0028130422 scopus 로고
    • Destabilization of glial fibrillary acidic protein mRNA in astrocytes by ammonia and protection by extracellular ATP
    • J.T. Neary, S.R. Whittemore, Q. Zhu, M.D. Norenberg Destabilization of glial fibrillary acidic protein mRNA in astrocytes by ammonia and protection by extracellular ATP J Neurochem 63 1994 2021 2027
    • (1994) J Neurochem , vol.63 , pp. 2021-2027
    • Neary, J.T.1    Whittemore, S.R.2    Zhu, Q.3    Norenberg, M.D.4
  • 23
    • 0032427875 scopus 로고    scopus 로고
    • Astroglial dysfunction in hepatic encephalopathy
    • M.D. Norenberg Astroglial dysfunction in hepatic encephalopathy Metab Brain Dis 13 1998 319 335
    • (1998) Metab Brain Dis , vol.13 , pp. 319-335
    • Norenberg, M.D.1
  • 24
    • 0031238547 scopus 로고    scopus 로고
    • The glial glutamate transporter in hyperammonemia and hepatic encephalopathy: Relation to energy metabolism and glutamatergic neurotransmission
    • M.D. Norenberg, Z. Huo, J.T. Neary, A. Roig-Cantesano The glial glutamate transporter in hyperammonemia and hepatic encephalopathy relation to energy metabolism and glutamatergic neurotransmission Glia 21 1997 124 133
    • (1997) Glia , vol.21 , pp. 124-133
    • Norenberg, M.D.1    Huo, Z.2    Neary, J.T.3    Roig-Cantesano, A.4
  • 25
    • 0018382256 scopus 로고
    • Fine structural localization of glutamine synthetase in astrocytes of rat brain
    • M.D. Norenberg, A. Martinez-Hernandez Fine structural localization of glutamine synthetase in astrocytes of rat brain Brain Res 161 1979 303 310
    • (1979) Brain Res , vol.161 , pp. 303-310
    • Norenberg, M.D.1    Martinez-Hernandez, A.2
  • 27
    • 0003161574 scopus 로고
    • Neuroglia: Quantitative aspects
    • E. Schoffeniels Pergamon Press Oxford *et al.
    • A. Pope Neuroglia quantitative aspects E. Schoffeniels Dynamic properties of glial cells 1978 Pergamon Press Oxford 13 20
    • (1978) Dynamic Properties of Glial Cells , pp. 13-20
    • Pope, A.1
  • 28
    • 0024842863 scopus 로고
    • Ammonium decreases excitatory synaptic transmission in cat spinal cord in vivo
    • W. Raabe Ammonium decreases excitatory synaptic transmission in cat spinal cord in vivo J Neurophysiol 62 1989 1461 1473
    • (1989) J Neurophysiol , vol.62 , pp. 1461-1473
    • Raabe, W.1
  • 29
    • 0038741859 scopus 로고    scopus 로고
    • Induction of the mitochondrial permeability transition in cultured astrocytes by glutamine
    • K.V. Rama Rao, A.R. Jayakumar, M.D. Norenberg Induction of the mitochondrial permeability transition in cultured astrocytes by glutamine Neurochem Int 43 2003 517 523
    • (2003) Neurochem Int , vol.43 , pp. 517-523
    • Rama Rao, K.V.1    Jayakumar, A.R.2    Norenberg, M.D.3
  • 30
    • 0015526761 scopus 로고
    • In vivo formation of methionine sulfoximine phosphate, a protein-bound metabolite of methionine sulfoximine
    • S.L.N. Rao, A. Meister In vivo formation of methionine sulfoximine phosphate, a protein-bound metabolite of methionine sulfoximine Biochemistry 11 1972 1123 1127
    • (1972) Biochemistry , vol.11 , pp. 1123-1127
    • Rao, S.L.N.1    Meister, A.2
  • 31
    • 0035869546 scopus 로고    scopus 로고
    • Cell-specific expression of connexins and evidence of restricted gap junctional coupling between glial cells and between neurons
    • J.E. Rash, T. Yasumura, F.E. Dudek, J.I. Nagy Cell-specific expression of connexins and evidence of restricted gap junctional coupling between glial cells and between neurons J Neurosci 21 2001 1983 2000
    • (2001) J Neurosci , vol.21 , pp. 1983-2000
    • Rash, J.E.1    Yasumura, T.2    Dudek, F.E.3    Nagy, J.I.4
  • 33
    • 0016426092 scopus 로고
    • Effect of methionine and methionine sulphoximine on rat brain S-adenosyl methionine levels
    • R.A. Schatz, O.Z. Sellinger Effect of methionine and methionine sulphoximine on rat brain S-adenosyl methionine levels J Neurochem 24 1975 63 66
    • (1975) J Neurochem , vol.24 , pp. 63-66
    • Schatz, R.A.1    Sellinger, O.Z.2
  • 34
    • 0014355252 scopus 로고
    • Methionine sulfoximine seizures: VIII. the dissociation of the convulsant and glutamine synthetase inhibitory effects
    • O.Z. Sellinger, J.M. Azcurra, W.G. Ohlsson Methionine sulfoximine seizures: VIII. The dissociation of the convulsant and glutamine synthetase inhibitory effects J Pharmacol Exp Ther 164 1968 212 222
    • (1968) J Pharmacol Exp Ther , vol.164 , pp. 212-222
    • Sellinger, O.Z.1    Azcurra, J.M.2    Ohlsson, W.G.3
  • 35
    • 0021683793 scopus 로고
    • Brain methylation and epileptogenesis: The case of methionine sulfoximine
    • O.Z. Sellinger, R.A. Schatz, R. Porta, T.E. Wilens Brain methylation and epileptogenesis the case of methionine sulfoximine Ann Neurol 16 Suppl 1984 S115 S120
    • (1984) Ann Neurol , vol.16 , Issue.SUPPL.
    • Sellinger, O.Z.1    Schatz, R.A.2    Porta, R.3    Wilens, T.E.4
  • 36
    • 0019812127 scopus 로고
    • Glial fibrillary acidic protein in hepatic encephalopathy: An immunohistochemical study
    • R.A. Sobel, S.J. De Armond, L.S. Forno, L.F. Eng Glial fibrillary acidic protein in hepatic encephalopathy an immunohistochemical study J Neuropathol Exp Neurol 40 1981 625 632
    • (1981) J Neuropathol Exp Neurol , vol.40 , pp. 625-632
    • Sobel, R.A.1    De Armond, S.J.2    Forno, L.S.3    Eng, L.F.4
  • 37
    • 0030456377 scopus 로고    scopus 로고
    • Long-term changes in glial fibrillary acidic protein and glutamine synthetase immunoreactivities in the supraoptic nucleus of portacaval shunted rats
    • I. Suarez, G. Bodega, E. Arilla, B. Fernandez Long-term changes in glial fibrillary acidic protein and glutamine synthetase immunoreactivities in the supraoptic nucleus of portacaval shunted rats Metab Brain Dis 11 1996 369 379
    • (1996) Metab Brain Dis , vol.11 , pp. 369-379
    • Suarez, I.1    Bodega, G.2    Arilla, E.3    Fernandez, B.4
  • 38
    • 0030919629 scopus 로고    scopus 로고
    • Region-selective glutamine synthetase expression in the rat central nervous system following portocaval anastomosis
    • I. Suarez, G. Bodega, E. Arilla, B. Fernandez Region-selective glutamine synthetase expression in the rat central nervous system following portocaval anastomosis Neuropathol Appl Neurobiol 23 1997 254 261
    • (1997) Neuropathol Appl Neurobiol , vol.23 , pp. 254-261
    • Suarez, I.1    Bodega, G.2    Arilla, E.3    Fernandez, B.4
  • 39
    • 0027013365 scopus 로고
    • Different response of astrocytes and Bergmann glial cells to portacaval shunt: An immunohistochemical study in the rat cerebellum
    • I. Suarez, G. Bodega, E. Arilla, M. Rubio, R. Villalba, B. Fernandez Different response of astrocytes and Bergmann glial cells to portacaval shunt an immunohistochemical study in the rat cerebellum Glia 6 1992 172 179
    • (1992) Glia , vol.6 , pp. 172-179
    • Suarez, I.1    Bodega, G.2    Arilla, E.3    Rubio, M.4    Villalba, R.5    Fernandez, B.6
  • 40
    • 0036093019 scopus 로고    scopus 로고
    • Glutamine synthetase in brain: Effect of ammonia
    • I. Suarez, G. Bodega, B. Fernandez Glutamine synthetase in brain effect of ammonia Neurochem Int 41 2002 123 142
    • (2002) Neurochem Int , vol.41 , pp. 123-142
    • Suarez, I.1    Bodega, G.2    Fernandez, B.3
  • 41
    • 0031012701 scopus 로고    scopus 로고
    • Methionine sulfoximine, a glutamine synthetase inhibitor, attenuates increased extracellular potassium activity during acute hyperammonemia
    • H. Sugimoto, R.C. Koehler, D.A. Wilson, S.W. Brusilow, R.J. Traystman Methionine sulfoximine, a glutamine synthetase inhibitor, attenuates increased extracellular potassium activity during acute hyperammonemia J Cereb Blood Flow Metab 17 1997 44 49
    • (1997) J Cereb Blood Flow Metab , vol.17 , pp. 44-49
    • Sugimoto, H.1    Koehler, R.C.2    Wilson, D.A.3    Brusilow, S.W.4    Traystman, R.J.5
  • 42
    • 0025093504 scopus 로고
    • Methionine sulfoximine reduces cortical infarct size in rats after middle cerebral artery occlusion
    • R.A. Swanson, K. Shiraishi, M.T. Morton, F.R. Sharp Methionine sulfoximine reduces cortical infarct size in rats after middle cerebral artery occlusion Stroke 21 1990 322 327
    • (1990) Stroke , vol.21 , pp. 322-327
    • Swanson, R.A.1    Shiraishi, K.2    Morton, M.T.3    Sharp, F.R.4
  • 43
    • 0026583030 scopus 로고
    • Effect of ammonium ions on synaptic transmission in the mammalian central nervous system
    • J.C. Szerb, R.F. Butterworth Effect of ammonium ions on synaptic transmission in the mammalian central nervous system Prog Neurobiol 39 1992 135 153
    • (1992) Prog Neurobiol , vol.39 , pp. 135-153
    • Szerb, J.C.1    Butterworth, R.F.2
  • 44
    • 0026004760 scopus 로고
    • Inhibition of brain glutamine accumulation prevents cerebral edema in hyperammonemic rats
    • H. Takahashi, R.C. Koehler, S.W. Brusilow, R.J. Traystman Inhibition of brain glutamine accumulation prevents cerebral edema in hyperammonemic rats Am J Physiol 261 1991 H825 H829
    • (1991) Am J Physiol , vol.261
    • Takahashi, H.1    Koehler, R.C.2    Brusilow, S.W.3    Traystman, R.J.4
  • 47
    • 0037311146 scopus 로고    scopus 로고
    • Selective increase of brain lactate synthesis in experimental acute liver failure: Results of a [H-C] nuclear magnetic resonance study
    • C. Zwingmann, N. Chatauret, D. Leibfritz, R.F. Butterworth Selective increase of brain lactate synthesis in experimental acute liver failure results of a [H-C] nuclear magnetic resonance study Hepatology 37 2003 420 428
    • (2003) Hepatology , vol.37 , pp. 420-428
    • Zwingmann, C.1    Chatauret, N.2    Leibfritz, D.3    Butterworth, R.F.4
  • 48
    • 1642513500 scopus 로고    scopus 로고
    • Selective alterations of brain osmolytes in acute liver failure: Protective effect of mild hypothermia
    • C. Zwingmann, N. Chatauret, C. Rose, D. Leibfritz, R.F. Butterworth Selective alterations of brain osmolytes in acute liver failure protective effect of mild hypothermia Brain Res 999 2004 118 123
    • (2004) Brain Res , vol.999 , pp. 118-123
    • Zwingmann, C.1    Chatauret, N.2    Rose, C.3    Leibfritz, D.4    Butterworth, R.F.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.