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Volumn 68, Issue 2, 2010, Pages 279-287

Intestinal mucus layer preservation in female rats attenuates gut injury after trauma-hemorrhagic shock

Author keywords

Gender; Gut injury; Hemorrhagic shock; Intestinal mucus layer; Trauma

Indexed keywords

EOSIN; HEMATOXYLIN; MUCIN; PROTEINASE; ACETYLCYSTEINE; ESTRADIOL; ESTROGEN RECEPTOR; MACROGOL; SEX HORMONE;

EID: 77249117806     PISSN: 00225282     EISSN: 15298809     Source Type: Journal    
DOI: 10.1097/TA.0b013e3181caa6bd     Document Type: Article
Times cited : (14)

References (47)
  • 1
    • 33745074125 scopus 로고    scopus 로고
    • Gut lymph hypothesis of early shock and trauma-induced multiple organ dysfunction syndrome: A new look at gut origin sepsis
    • Deitch EA, Xu DZ, Lu Q. Gut lymph hypothesis of early shock and trauma-induced multiple organ dysfunction syndrome: a new look at gut origin sepsis. J Organ Dysfunct. 2006;2:70-79.
    • (2006) J Organ Dysfunct , vol.2 , pp. 70-79
    • Deitch, E.A.1    Xu, D.Z.2    Lu, Q.3
  • 2
    • 34548682085 scopus 로고    scopus 로고
    • Intestinal crosstalk: A new paradigm for understanding the gut as the "motor"of critical illness
    • Clark JA, Coopersmith CM. Intestinal crosstalk: a new paradigm for understanding the gut as the "motor" of critical illness. Shock. 2007;28: 384-393.
    • (2007) Shock , vol.28 , pp. 384-393
    • Clark, J.A.1    Coopersmith, C.M.2
  • 3
    • 53949120704 scopus 로고    scopus 로고
    • Role of intestinal mucus and pancreatic proteases in the pathogenesis of trauma-hemorrhagic shock induced gut barrier failure and multiple organ dysfunction syndrome
    • Sharpe SM, Doucet DR, Qin X, Deitch EA. Role of intestinal mucus and pancreatic proteases in the pathogenesis of trauma-hemorrhagic shock induced gut barrier failure and multiple organ dysfunction syndrome. J Organ Dysfunct. 2008;4:168-176.
    • (2008) J Organ Dysfunct , vol.4 , pp. 168-176
    • Sharpe, S.M.1    Doucet, D.R.2    Qin, X.3    Deitch, E.A.4
  • 4
    • 0026081411 scopus 로고
    • Functional biology of intestinal goblet cells
    • Specian RD, Oliver MG. Functional biology of intestinal goblet cells. Am J Physiol. 1991;260:C183-C193.
    • (1991) Am J Physiol , vol.260
    • Specian, R.D.1    Oliver, M.G.2
  • 5
    • 33947310779 scopus 로고    scopus 로고
    • Relationship between disruption of the unstirred mucus layer and intestinal restitution in loss of gut barrier function after trauma hemorrhagic shock
    • Rupani B, Caputo F, Watkins A, et al.. Relationship between disruption of the unstirred mucus layer and intestinal restitution in loss of gut barrier function after trauma hemorrhagic shock. Surgery. 2004;141: 481-489.
    • (2004) Surgery , vol.141 , pp. 481-489
    • Rupani, B.1    Caputo, F.2    Watkins, A.3
  • 6
    • 43349102298 scopus 로고    scopus 로고
    • Gender dimorphism following injury: Making the connection from bench to bedside
    • Sperry JL, Minei JP. Gender dimorphism following injury: making the connection from bench to bedside. J Leukoc Biol. 2008;83:499-506.
    • (2008) J Leukoc Biol , vol.83 , pp. 499-506
    • Sperry, J.L.1    Minei, J.P.2
  • 7
    • 67650519406 scopus 로고    scopus 로고
    • Females have fewer complications and lower mortality following trauma than similarly injured males: A risk adjusted analysis of adults in the National Trauma Data Bank
    • Haider AH, Crompton JG, Oyetunji T, et al.. Females have fewer complications and lower mortality following trauma than similarly injured males: a risk adjusted analysis of adults in the National Trauma Data Bank. Surgery. 2009;146:308-315.
    • (2009) Surgery , vol.146 , pp. 308-315
    • Haider, A.H.1    Crompton, J.G.2    Oyetunji, T.3
  • 9
    • 34548188065 scopus 로고    scopus 로고
    • Hormonally active women tolerate shock-trauma better than do men: A prospective study of over 4000 trauma patients
    • discussion 453-455
    • Deitch EA, Livingston DH, Lavery RF, Monaghan SF, Bongu A, Machiedo GW. Hormonally active women tolerate shock-trauma better than do men: a prospective study of over 4000 trauma patients. Ann Surg. 2007;246:447- 453; discussion 453-455.
    • (2007) Ann Surg , vol.246 , pp. 447-453
    • Deitch, E.A.1    Livingston, D.H.2    Lavery, R.F.3    Monaghan, S.F.4    Bongu, A.5    MacHiedo, G.W.6
  • 10
    • 0141522755 scopus 로고    scopus 로고
    • Gut injury and gut-induced lung injury after trauma hemorrhagic shock is gender and estrus cycle specific
    • Caruso JM, Deitch EA, Xu DZ, Lu Q, Dayal SD. Gut injury and gut-induced lung injury after trauma hemorrhagic shock is gender and estrus cycle specific. J Trauma. 2003;55:531-539.
    • (2003) J Trauma , vol.55 , pp. 531-539
    • Caruso, J.M.1    Deitch, E.A.2    Xu, D.Z.3    Lu, Q.4    Dayal, S.D.5
  • 11
    • 11144283121 scopus 로고    scopus 로고
    • Sex hormones modulate distant organ injury in a trauma/hemorrhagic shock model and a burn model
    • Ananthakrishnan P, Cohen DB, Xu DZ, et al.. Sex hormones modulate distant organ injury in a trauma/hemorrhagic shock model and a burn model. Surgery. 2005;137:56-65.
    • (2005) Surgery , vol.137 , pp. 56-65
    • Ananthakrishnan, P.1    Cohen, D.B.2    Xu, D.Z.3
  • 12
    • 37549043869 scopus 로고    scopus 로고
    • Resistance of the female, as opposed to the male, intestine to I/Rmediated injury is associated with increased resistance to gut-induced distant organ injury
    • Deitch EA, Feketeova E, Lu Q, Lu Q, Feketeova E, Deitch EA. Resistance of the female, as opposed to the male, intestine to I/Rmediated injury is associated with increased resistance to gut-induced distant organ injury. Shock. 2008;29:78-83.
    • (2008) Shock , vol.29 , pp. 78-83
    • Deitch, E.A.1    Feketeova, E.2    Lu, Q.3    Lu, Q.4    Feketeova, E.5    Deitch, E.A.6
  • 14
    • 0032471452 scopus 로고    scopus 로고
    • Gut derived mesenteric lymph but not portal blood increases endothelial cell permeability and promotes lung injury after hemorrhagic shock
    • Magnotti LJ, Upperman JS, Xu DZ, Lu Q, Deitch EA. Gut derived mesenteric lymph but not portal blood increases endothelial cell permeability and promotes lung injury after hemorrhagic shock. Ann Surg. 1998;228:518-527.
    • (1998) Ann Surg , vol.228 , pp. 518-527
    • Magnotti, L.J.1    Upperman, J.S.2    Xu, D.Z.3    Lu, Q.4    Deitch, E.A.5
  • 15
    • 0030737814 scopus 로고    scopus 로고
    • Histochemistry of the surface mucus gel layer of the human colon
    • Matsuo K, Ota H, Akamatsu T, Sugiyama A, Katsuyama T. Histochemistry of the surface mucus gel layer of the human colon. Gut. 1997;40: 782-789.
    • (1997) Gut , vol.40 , pp. 782-789
    • Matsuo, K.1    Ota, H.2    Akamatsu, T.3    Sugiyama, A.4    Katsuyama, T.5
  • 17
    • 28044462916 scopus 로고    scopus 로고
    • Functional and morphological changes of the gut barrier during the restitution process after hemorrhagic shock
    • Chang JX, Chen S, Ma LP, et al.. Functional and morphological changes of the gut barrier during the restitution process after hemorrhagic shock. World J Gastroenterol. 2005;11:5485-5491.
    • (2005) World J Gastroenterol , vol.11 , pp. 5485-5491
    • Chang, J.X.1    Chen, S.2    Ma, L.P.3
  • 18
    • 0026744448 scopus 로고
    • Multiple organ failure: Pathophysiology and potential future
    • Deitch EA. Multiple organ failure: pathophysiology and potential future. Ann Surg. 1992;216:117-134.
    • (1992) Ann Surg , vol.216 , pp. 117-134
    • Deitch, E.A.1
  • 19
    • 0000607961 scopus 로고
    • Role of xanthine oxidase and neutrophils in ischemiareperfusion injury
    • Granger DN. Role of xanthine oxidase and neutrophils in ischemiareperfusion injury. Am J Physiol. 1988;255:H1269-H1275.
    • (1988) Am J Physiol , vol.255
    • Granger, D.N.1
  • 21
    • 0034652190 scopus 로고    scopus 로고
    • Generation of in vivo activating factors in the ischemic intestine by pancreatic enzymes
    • Mitsuoka H, Kistler EB, Schmid-Schonbein GW. Generation of in vivo activating factors in the ischemic intestine by pancreatic enzymes. Proc Natl Acad Sci USA. 2000;97:1772-1777.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 1772-1777
    • Mitsuoka, H.1    Kistler, E.B.2    Schmid-Schonbein, G.W.3
  • 22
    • 1942511057 scopus 로고    scopus 로고
    • Serine proteases are involved in the pathogenesis of trauma-hemorrhagic shock-induced gut and lung injury
    • Deitch EA, Shi HP, Lu Q, Feketeova E, Xu DZ. Serine proteases are involved in the pathogenesis of trauma-hemorrhagic shock-induced gut and lung injury. Shock. 2003;19:452-456.
    • (2003) Shock , vol.19 , pp. 452-456
    • Deitch, E.A.1    Shi, H.P.2    Lu, Q.3    Feketeova, E.4    Xu, D.Z.5
  • 23
    • 0035026232 scopus 로고    scopus 로고
    • The adherent gastrointestinal mucus gel layer: Thickness and physical state in vivo
    • Atuma C, Strugala V, Allen A, Holm L. The adherent gastrointestinal mucus gel layer: thickness and physical state in vivo. Am J Physiol. 2001;280:G922-G929.
    • (2001) Am J Physiol , vol.280
    • Atuma, C.1    Strugala, V.2    Allen, A.3    Holm, L.4
  • 24
    • 10644261336 scopus 로고    scopus 로고
    • Gastroduodenal mucus bicarbonate barrier: Protection against acid and pepsin
    • Allen A, Flemstrom G. Gastroduodenal mucus bicarbonate barrier: protection against acid and pepsin. Am J Physiol Cell Physiol. 2005; 288:C1-C19.
    • (2005) Am J Physiol Cell Physiol , vol.288
    • Allen, A.1    Flemstrom, G.2
  • 25
    • 0020761116 scopus 로고
    • Gastric mucosal barrier: Hydrophobic lining to the lumen of the stomach
    • Hills BA, Butler BD, Lichtenberger LM. Gastric mucosal barrier: hydrophobic lining to the lumen of the stomach. Am J Physiol. 1983; 244:G561-G568.
    • (1983) Am J Physiol , vol.244
    • Hills, B.A.1    Butler, B.D.2    Lichtenberger, L.M.3
  • 26
    • 0025017363 scopus 로고
    • Luminal surface hydrophobicity of canine gastric mucosa is dependent on a surface mucous gel
    • Goddard PJ, Kao YJ, Lichtenberger LM. Luminal surface hydrophobicity of canine gastric mucosa is dependent on a surface mucous gel. Gastroenterology. 1990;98:361-370.
    • (1990) Gastroenterology , vol.98 , pp. 361-370
    • Goddard, P.J.1    Kao, Y.J.2    Lichtenberger, L.M.3
  • 28
  • 29
    • 0030968004 scopus 로고    scopus 로고
    • Role of bacterial adherence and the mucus barrier on bacterial translocation: Effects of protein malnutrition and endotoxin in rats
    • Katayama M, Xu D, Specian RD, Deitch EA. Role of bacterial adherence and the mucus barrier on bacterial translocation: effects of protein malnutrition and endotoxin in rats. Ann Surg. 1997;225:317-326.
    • (1997) Ann Surg , vol.225 , pp. 317-326
    • Katayama, M.1    Xu, D.2    Specian, R.D.3    Deitch, E.A.4
  • 30
    • 10744233061 scopus 로고    scopus 로고
    • High-molecular weight polyethylene glycol prevents lethal sepsis due to intestinal Pseudomonas aeruginosa
    • Wu L, Zaborina O, Zahorin A, et al.. High-molecular weight polyethylene glycol prevents lethal sepsis due to intestinal Pseudomonas aeruginosa. Gastroenterology. 2004;126:488-498.
    • (2004) Gastroenterology , vol.126 , pp. 488-498
    • Wu, L.1    Zaborina, O.2    Zahorin, A.3
  • 31
    • 0018937359 scopus 로고
    • Significance of the goblet-cell mucin layer, the outermost luminal barrier to passage through the gut wall
    • Nimmerfall F, Rosenthaler J. Significance of the goblet-cell mucin layer, the outermost luminal barrier to passage through the gut wall. Biochem Biophys Res Commun. 1980;94:960-966.
    • (1980) Biochem Biophys Res Commun , vol.94 , pp. 960-966
    • Nimmerfall, F.1    Rosenthaler, J.2
  • 32
    • 39449129981 scopus 로고    scopus 로고
    • Hydrophobicity of mucosal surface and its relationship to gut barrier function
    • Qin X, Caputo FJ, Xu D, Deitch EA. Hydrophobicity of mucosal surface and its relationship to gut barrier function. Shock. 2008;29: 372-376.
    • (2008) Shock , vol.29 , pp. 372-376
    • Qin, X.1    Caputo, F.J.2    Xu, D.3    Deitch, E.A.4
  • 33
    • 13344283408 scopus 로고    scopus 로고
    • Adhesive mucous gel layer and mucus release as intestinal barrier in rats
    • Iiboshi Y, Nezu R, Cui L, et al.. Adhesive mucous gel layer and mucus release as intestinal barrier in rats. J Parenter Enteral Nutr. 1996;20: 98-104.
    • (1996) J Parenter Enteral Nutr , vol.20 , pp. 98-104
    • Iiboshi, Y.1    Nezu, R.2    Cui, L.3
  • 34
    • 0020761116 scopus 로고
    • Gastric mucosal barrier: Hydrophobic lining to the lumen of the stomach
    • Hills BA, Butler BD, Lichtenberger LM. Gastric mucosal barrier: hydrophobic lining to the lumen of the stomach. Am J Physiol. 1983; 244:G561-G568.
    • (1983) Am J Physiol , vol.244
    • Hills, B.A.1    Butler, B.D.2    Lichtenberger, L.M.3
  • 35
    • 0034030066 scopus 로고    scopus 로고
    • Surface hydrophobicity of the rat colonic mucosa is a defensive barrier against macromolecules and toxins
    • Lugea A, Salas A, Casalot J, Guarner F, Malagelada JR. Surface hydrophobicity of the rat colonic mucosa is a defensive barrier against macromolecules and toxins. Gut. 2000;46:515-521.
    • (2000) Gut , vol.46 , pp. 515-521
    • Lugea, A.1    Salas, A.2    Casalot, J.3    Guarner, F.4    Malagelada, J.R.5
  • 37
    • 0017862114 scopus 로고
    • Intestinal mucins in health and disease
    • Forstner JF. Intestinal mucins in health and disease. Digestion. 1978;17: 234-263.
    • (1978) Digestion , vol.17 , pp. 234-263
    • Forstner, J.F.1
  • 38
    • 0026032212 scopus 로고
    • Rat small intestinal mucins: A quantitative analysis
    • Kemper AC, Specian RD. Rat small intestinal mucins: a quantitative analysis. Anat Rec. 1991;229:219-226.
    • (1991) Anat Rec , vol.229 , pp. 219-226
    • Kemper, A.C.1    Specian, R.D.2
  • 39
    • 7044235144 scopus 로고    scopus 로고
    • Pancreatic duct ligation reduced lung injury following trauma and hemorrhagic shock
    • Cohen DB, Magnotti LJ, Lu Q, et al.. Pancreatic duct ligation reduced lung injury following trauma and hemorrhagic shock. Ann Surg. 2004; 240:885-891.
    • (2004) Ann Surg , vol.240 , pp. 885-891
    • Cohen, D.B.1    Magnotti, L.J.2    Lu, Q.3
  • 40
    • 34548666736 scopus 로고    scopus 로고
    • Pancreatic duct ligation abrogates the trauma hemorrhage-induced gut barrier failure and the subsequent production of biologically active intestinal lymph
    • Caputo FJ, Rupani B, Watkins AC, et al.. Pancreatic duct ligation abrogates the trauma hemorrhage-induced gut barrier failure and the subsequent production of biologically active intestinal lymph. Shock. 2007;28:441-446.
    • (2007) Shock , vol.28 , pp. 441-446
    • Caputo, F.J.1    Rupani, B.2    Watkins, A.C.3
  • 41
    • 67650339973 scopus 로고    scopus 로고
    • Organ blood flow and the central hemodynamic response is better preserved in female, as opposed to male rats, after trauma-hemorrhagic shock
    • Deitch EA, Chu H, Xu DZ. Organ blood flow and the central hemodynamic response is better preserved in female, as opposed to male rats, after trauma-hemorrhagic shock. J Trauma. 2008;65:566-572.
    • (2008) J Trauma , vol.65 , pp. 566-572
    • Deitch, E.A.1    Chu, H.2    Xu, D.Z.3
  • 42
    • 0038781968 scopus 로고    scopus 로고
    • Gender dimorphic tissue perfusion response after acute hemorrhage and resuscitation: Role of vascular endothelial cell function
    • Ba ZF, Kuebler JF, Rue LW, Bland KI, Wang P, Chaudry IH. Gender dimorphic tissue perfusion response after acute hemorrhage and resuscitation: role of vascular endothelial cell function. Am J Physiol Heart Circ Physiol. 2003;284:H2162-H2169.
    • (2003) Am J Physiol Heart Circ Physiol , vol.284
    • Ba, Z.F.1    Kuebler, J.F.2    Rue, L.W.3    Bland, K.I.4    Wang, P.5    Chaudry, I.H.6
  • 43
    • 0042763868 scopus 로고    scopus 로고
    • Morphological characterization of different human cervical mucus types using light and scanning electron microscopy
    • Menárguez M, Pastor LM, Odeblad E. Morphological characterization of different human cervical mucus types using light and scanning electron microscopy. Hum Reprod. 2003;18:1782-1789.
    • (2003) Hum Reprod , vol.18 , pp. 1782-1789
    • Menárguez, M.1    Pastor, L.M.2    Odeblad, E.3
  • 44
    • 59149102796 scopus 로고    scopus 로고
    • Signal pathway of 17beta-estradiolinduced MUC5B expression in human airway epithelial cells
    • Choi HJ, Chung YS, Kim HJ, et al.. Signal pathway of 17beta- estradiolinduced MUC5B expression in human airway epithelial cells. Am J Respir Cell Mol Biol. 2009;40:168-178.
    • (2009) Am J Respir Cell Mol Biol , vol.40 , pp. 168-178
    • Choi, H.J.1    Chung, Y.S.2    Kim, H.J.3
  • 45
    • 34548452597 scopus 로고    scopus 로고
    • Mechanism of the nongenomic effects of estrogen on intestinal myeloperoxidase activity following trauma-hemorrhage: Up-regulation of the PI-3K/Akt pathway
    • Yu HP, Hsieh YC, Suzuki T, et al.. Mechanism of the nongenomic effects of estrogen on intestinal myeloperoxidase activity following trauma-hemorrhage: up-regulation of the PI-3K/Akt pathway. J Leukoc Biol. 2007;82:774-780.
    • (2007) J Leukoc Biol , vol.82 , pp. 774-780
    • Yu, H.P.1    Hsieh, Y.C.2    Suzuki, T.3
  • 46
    • 47549107645 scopus 로고    scopus 로고
    • Mechanism of estrogen-mediated intestinal protection following trauma-hemorrhage: P38 MAPK-dependent upregulation of HO-1
    • Hsu JT, Kan WH, Hsieh CH, et al.. Mechanism of estrogen-mediated intestinal protection following trauma-hemorrhage: p38 MAPK-dependent upregulation of HO-1. Am J Physiol Regul Integr Comp Physiol. 2008;294:R1825-R1831.
    • (2008) Am J Physiol Regul Integr Comp Physiol , vol.294
    • Hsu, J.T.1    Kan, W.H.2    Hsieh, C.H.3
  • 47
    • 13844315702 scopus 로고    scopus 로고
    • The female intestine is more resistant than the male intestine to gut injury and inflammation when subjected to conditions associated with shock states
    • Homma H, Hoy E, Xu D, Lu Q, Feinman R, Deitch EA. The female intestine is more resistant than the male intestine to gut injury and inflammation when subjected to conditions associated with shock states. Am J Physiol Gastrointest Liver Physiol. 2005;288:G466-G472.
    • (2005) Am J Physiol Gastrointest Liver Physiol , vol.288
    • Homma, H.1    Hoy, E.2    Xu, D.3    Lu, Q.4    Feinman, R.5    Deitch, E.A.6


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