Mechanism of estrogen-mediated intestinal protection following trauma-hemorrhage: P38 MAPKdependent upregulation of HO-1 (American Journal of Physiology- Regulatory Integrative Comparative Physiology (2008) 294, (R1829-R1831) DOI: 10.1152/ajpregu.00112.2008);Mechanism of estrogen-mediated intestinal protection following trauma-hemorrhage: p38 MAPK-dependent upregulation of HO-1

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 294, Issue 6, 2008, Pages

  Hsu, Jun Te ^a,c   Kan, Wen Hong ^a   Hsieh, Chi Hsun ^a,d   Choudhry, Mashkoor A ^a   Schwacha, Martin G ^a   Bland, Kirby I ^a   Chaudry, Irshad H ^a,b  

^a Kentucky   (United States)

^b UNIVERSITY OF ALABAMA SCHOOL OF MEDICINE   (United States)

^c CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^d CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

CINC 1; MIP 2; MPO; p38 MAPK inhibitor

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CYCLODEXTRIN; CYTOKINE INDUCED NEUTROPHIL CHEMOATTRACTANT; CYTOKINE INDUCED NEUTROPHIL CHEMOATTRACTANT 1; ESTRADIOL; ESTROGEN; HEME OXYGENASE 1; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6; LACTIC ACID; MACROPHAGE INFLAMMATORY PROTEIN 2; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; MYELOPEROXIDASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CXCL1 CHEMOKINE; CXCL1 PROTEIN, RAT; CXCL2 CHEMOKINE; CXCL2 PROTEIN, RAT; PEROXIDASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLEEDING; BLOOD PRESSURE; CELL TYPE; CONTROLLED STUDY; ENZYME ACTIVATION; FLUID THERAPY; INJURY; INTESTINE INJURY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RESUSCITATION; SHOCK; SPRAGUE DAWLEY RAT; TREATMENT OUTCOME; ANIMAL; DRUG EFFECT; HEMORRHAGIC SHOCK; INTESTINE; METABOLISM; PHYSIOLOGY; UPREGULATION;

ANIMALS; CHEMOKINE CXCL1; CHEMOKINE CXCL2; ESTROGENS; HEME OXYGENASE-1; HEMORRHAGE; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-6; INTESTINES; LACTIC ACID; MALE; MODELS, ANIMAL; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PEROXIDASE; RATS; RATS, SPRAGUE-DAWLEY; SHOCK, HEMORRHAGIC; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION; WOUNDS AND INJURIES;

EID: 47549107645     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.zh6-6440-corr.2008     Document Type: Erratum

References (41)

1. Angle N, Hoyt DB, Coimbra R, Liu F, Herdon-Remelius C, Loomis W, Junger WG. Hypertonic saline resuscitation diminishes lung injury by suppressing neutrophil activation after hemorrhagic shock. Shock 9: 164-170, 1998.
2. Aoudjit L, Stanciu M, Li H, Lemay S, Takano T. p38 Mitogen-activated protein kinase protects glomerular epithelial cells from complement-mediated cell injury. Am J Physiol Renal Physiol 285: F765-F774, 2003.
3. Ba ZF, Shimizu T, Szalay L, Bland KI, Chaudry IH. Gender differences in small intestinal perfusion following trauma hemorrhage: the role of endothelin-1. Am J Physiol Gastrointest Liver Physiol 288: G860-G865, 2005.
4. Bauer I, Rensing H, Florax A, Ulrich C, Pistorius G, Redl H, Bauer M. Expression pattern and regulation of heme oxygenase-1/heat shock protein 32 in human liver cells. Shock 20: 116-122, 2003.
5. Bonello N, Norman RJ. Soluble adhesion molecules in serum throughout the menstrual cycle. Hum Reprod 17: 2272-2278, 2002.
6. Bornman L, Steinmann CM, Gericke GS, Polla BS. In vivo heat shock protects rat myocardial mitochondria. Biochem Biophys Res Commun 246: 836-840, 1998.
7. Choudhry MA, Schwacha MG, Hubbard WJ, Kerby JD, Rue LW, Bland KI, Chaudry IH. Gender differences in acute response to trauma-hemorrhage. Shock 24, Suppl 1: 101-106, 2005.
8. Dayal SD, Hasko G, Lu Q, Xu DZ, Caruso JM, Sambol JT, Deitch EA. Trauma/hemorrhagic shock mesenteric lymph upregulates adhesion molecule expression and IL-6 production in human umbilical vein endothelial cells. Shock 17: 491-495, 2002.
9. Deitch EA, Livingston DH, Lavery RF, Monaghan SF, Bongu A, Machiedo GW. Hormonally active women tolerate shock-trauma better than do men: a prospective study of over 4000 trauma patients. Ann Surg 246: 447-453, 2007.
10. Drechsler Y, Dolganiuc A, Norkina O, Romics L, Li W, Kodys K, Bach FH, Mandrekar P, Szabo G. Heme oxygenase-1 mediates the anti-inflammatory effects of acute alcohol on IL-10 induction involving p38 MAPK activation in monocytes. J Immunol 177: 2592-2600, 2006.
11. Frink M, Pape HC, van GM, Krettek C, Chaudry IH, Hildebrand F. Influence of sex and age on mods and cytokines after multiple injuries. Shock 27: 151-156, 2007.
12. George RL, McGwin G Jr, Metzger J, Chaudry IH and Rue LW III. The association between gender and mortality among trauma patients as modified by age. J Trauma 54: 464-471, 2003.
13. Guo RF, Riedemann NC, Laudes IJ, Sarma VJ, Kunkel RG, Dilley KA, Paulauskis JD, Ward PA. Altered neutrophil trafficking during sepsis. J Immunol 169: 307-314, 2002.
14. Homma H, Hoy E, Xu DZ, Lu Q, Feinman R, Deitch EA. The female intestine is more resistant than the male intestine to gut injury and inflammation when subjected to conditions associated with shock states. Am J Physiol Gastrointest Liver Physiol 288: G466-G472, 2005.
15. Hsu JT, Hsieh YC, Kan WH, Chen JG, Choudhry MA, Schwacha MG, Bland KI, Chaudry IH. Role of p38 mitogen-activated protein kinase pathway in estrogen-mediated cardioprotection following trauma-hemorrhage. Am J Physiol Heart Circ Physiol 292: H2982-H2987, 2007.
16. Hsu JT, Kan WH, Hsieh CH, Choudhry MA, Schwacha MG, Bland KI, Chaudry IH. Mechanism of estrogen-mediated attenuation of hepatic injury following trauma-hemorrhage: Akt-dependent HO-1 up-regulation. J Leukoc Biol 82: 1019-1026, 2007.
17. Ito K, Ozasa H, Kojima N, Miura M, Iwa T, Senoo H, Horikawa S. Pharmacological preconditioning protects lung injury induced by intestinal ischemia/reperfusion in rat. Shock 19: 462-468, 2003.
18. Kher A, Wang M, Tsai BM, Pitcher JM, Greenbaum ES, Nagy RD, Patel KM, Wairiuko GM, Markel TA, Meldrum DR. Sex differences in the myocardial inflammatory response to acute injury. Shock 23: 1-10, 2005.
19. Maier M, Strobele H, Voges J, Bauer C, Marzi I. Attenuation of leukocyte adhesion by recombinant TNF-binding protein after hemorrhagic shock in the rat. Shock 19: 457-461, 2003.
20. Meldrum DR, McIntyre RC, Sheridan BC, Cleveland JC Jr, Fullerton DA and Harken AH. L-Arginine decreases alveolar macrophage proinflammatory monokine production during acute lung injury by a nitric oxide synthase-dependent mechanism. J Trauma 43: 888-893, 1997.
21. Meng X, Ao L, Song Y, Raeburn CD, Fullerton DA, Harken AH. Signaling for myocardial depression in hemorrhagic shock: roles of Toll-like receptor 4 and p55 TNF-alpha receptor. Am J Physiol Regul Integr Comp Physiol 288: R600-R606, 2005.
22. Moore FA. The role of the gastrointestinal tract in postinjury multiple organ failure. Am J Surg 178: 449-453, 1999.
23. Morita T, Perrella MA, Lee ME, Kourembanas S. Smooth muscle cell-derived carbon monoxide is a regulator of vascular cGMP. Proc Natl Acad Sci USA 92: 1475-1479, 1995.
24. Murphy TJ, Paterson HM, Mannick JA, Lederer JA. Injury, sepsis, and the regulation of Toll-like receptor responses. J Leukoc Biol 75: 400-407, 2004.
25. Nakano A, Baines CP, Kim SO, Pelech SL, Downey JM, Cohen MV, Critz SD. Ischemic preconditioning activates MAPKAPK2 in the isolated rabbit heart: evidence for involvement of p38 MAPK. Circ Res 86: 144-151, 2000.
26. Otterbein LE, Bach FH, Alam J, Soares M, Tao LH, Wysk M, Davis RJ, Flavell RA, Choi AM. Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway. Nat Med 6: 422-428, 2000.
27. Otterbein LE, Kolls JK, Mantell LL, Cook JL, Alam J, Choi AM. Exogenous administration of heme oxygenase-1 by gene transfer provides protection against hyperoxia-induced lung injury. J Clin Invest 103: 1047-1054, 1999.
28. Otterbein LE, Otterbein SL, Ifedigbo E, Liu F, Morse DE, Fearns C, Ulevitch RJ, Knickelbein R, Flavell RA, Choi AM. MKK3 mitogen-activated protein kinase pathway mediates carbon monoxide-induced protection against oxidant-induced lung injury. Am J Pathol 163: 2555-2563, 2003.
29. Shanley TP, Schmal H, Warner RL, Schmid E, Friedl HP, Ward PA. Requirement for C-X-C chemokines (macrophage inflammatory protein-2 and cytokine-induced neutrophil chemoattractant) in IgG immune complex-induced lung injury. J Immunol 158: 3439-3448, 1997.
30. Sheng WH, Chiang BL, Chang SC, Ho HN, Wang JT, Chen YC, Hsiao CH, Hseuh PR, Chie WC, Yang PC. Clinical manifestations and inflammatory cytokine responses in patients with severe acute respiratory syndrome. J Formos Med Assoc 104: 715-723, 2005.
31. Shifflett DE, Jones SL, Moeser AJ, Blikslager AT. Mitogen-activated protein kinases regulate COX-2 and mucosal recovery in ischemic-injured porcine ileum. Am J Physiol Gastrointest Liver Physiol 286: G906-G913, 2004.
32. Soares MP, Seldon MP, Gregoire IP, Vassilevskaia T, Berberat PO, Yu J, Tsui TY, Bach FH. Heme oxygenase-1 modulates the expression of adhesion molecules associated with endothelial cell activation. J Immunol 172: 3553-3563, 2004.
33. Stork S, von SC, Angerer P. The effect of 17β-estradiol on endothelial and inflammatory markers in postmenopausal women: a randomized, controlled trial. Atherosclerosis 165: 301-307, 2002.
34. Szalay L, Shimizu T, Schwacha MG, Choudhry MA, Rue LW, III, Bland KI, Chaudry IH. Mechanism of salutary effects of estradiol on organ function after trauma-hemorrhage: upregulation of heme oxygenase. Am J Physiol Heart Circ Physiol 289: H92-H98, 2005.
35. Wang R, Wu L, Wang Z. The direct effect of carbon monoxide on KCa channels in vascular smooth muscle cells. Pflügers Arch 434: 285-291, 1997.
36. Wanner GA, Muller PE, Ertel W, Bauer M, Menger MD, Messmer K. Differential effect of anti-TNF-α antibody on proinflammatory cytokine release by Kupffer cells following liver ischemia and reperfusion. Shock 11: 391-395, 1999.
37. Wijayanti N, Kietzmann T, Immenschuh S. Heme oxygenase-1 gene activation by the NAD(P)H oxidase inhibitor 4-(2-aminoethyl) benzenesulfonyl fluoride via a protein kinase B, p38-dependent signaling pathway in monocytes. J Biol Chem 280: 21820-21829, 2005.
38. Yu HP, Choudhry MA, Shimizu T, Hsieh YC, Schwacha MG, Yang S, Chaudry IH. Mechanism of the salutary effects of flutamide on intestinal myeloperoxidase activity following trauma-hemorrhage: up-regulation of estrogen receptor-β-dependent HO-1. J Leukoc Biol 79: 277-284, 2006.
39. Yu HP, Shimizu T, Hsieh YC, Suzuki T, Choudhry MA, Schwacha MG, Chaudry IH. Tissue-specific expression of estrogen receptors and their role in the regulation of neutrophil infiltration in various organs following trauma-hemorrhage. J Leukoc Biol 79: 963-970, 2006.
40. Zou L, Yang S, Hu S, Chaudry IH, Marchase RB, Chatham JC. The protective effects of PUGNAc on cardiac function after trauma-hemorrhage are mediated via increased protein O-GlcNAc levels. Shock 27: 402-408, 2007.
41. Zuckerbraun BS, McCloskey CA, Gallo D, Liu F, Ifedigbo E, Otterbein LE, Billiar TR. Carbon monoxide prevents multiple organ injury in a model of hemorrhagic shock and resuscitation. Shock 23: 527-532, 2005.