Gut-derived mesenteric lymph but not portal blood increases endothelial cell permeability and promotes lung injury after hemorrhagic shock

Annals of Surgery

Volumn 228, Issue 4, 1998, Pages 518-527

  Magnotti, Louis J ^a   Upperman, Jeffrey S ^a   Xu, Da Zhong ^a   Lu, Qi ^a   Deitch, Edwin A ^a  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MYELOPEROXIDASE;

APOPTOSIS; BACTEREMIA; CELL MEMBRANE PERMEABILITY; CONFERENCE PAPER; CONTROLLED STUDY; ENDOTHELIUM CELL; ENDOTOXEMIA; HEMORRHAGIC SHOCK; HUMAN; HUMAN CELL; INTESTINE LYMPH; LUNG ALVEOLUS CELL; LUNG INJURY; LUNG LAVAGE; LYMPH FLOW; MESENTERY; MONOLAYER CULTURE; MULTIPLE ORGAN FAILURE; PATHOGENESIS; PORTAL VEIN BLOOD; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPERFUSION;

ANIMALS; BIOLOGICAL FACTORS; BLOOD PHYSIOLOGY; CELL DEATH; CELL MEMBRANE PERMEABILITY; ENDOTHELIUM; HUMANS; LUNG; LYMPH; MALE; MESENTERY; RATS; RATS, SPRAGUE-DAWLEY; SHOCK, HEMORRHAGIC;

EID: 0032471452     PISSN: 00034932     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000658-199810000-00008     Document Type: Conference Paper

References (37)

1. Deitch EA. Multiple organ failure pathophysiology and potential future therapy. Ann Surg 1992; 216:117-134.
2. Johnston TD, Fischer R, Chen Y, Reed RL. Lung injury from gut ischemia: insensitivity to portal blood flow diversion. J Trauma 1993; 5:508-511.
3. Deitch EA, Xu DZ, Franko L, Ayala A, Chaudry IH. Evidence favoring the role of the gut as a cytokine-generating organ in rats subjected to hemorrhagic shock. Shock 1994; 1:141-146.
4. Mainous MR, Ertel W, Chaudry IH, Deitch EA. The gut: a cytokine-generating organ in systemic inflammation? Shock 1995; 4:193-199.
5. Ayala A, Wang P, Ba ZF, Perrin, Ertel W, Chaudry IH. Differential alterations in plasma IL-6 and TNF levels after trauma and hemorrhage. Am J Physiol 1991; 260:R167-R171.
6. Endo S, Inada K, Yamada Y, et al. Plasma endotoxin and cytokine concentrations in patients with hemorrhagic shock. Crit Care Med 1994; 22:949-955.
7. Roumen RM, Hendriks T, van der Ven Jongekrijg J, et al. Cytokine patterns in patients after major vascular surgery, hemorrhagic shock and severe blunt trauma. Relation with subsequent adult respiratory distress syndrome and multiple organ failure. Ann Surg 1993; 218:769-776.
8. Peitzman AB, Billiar TR, Harbrecht BG, Kelly E, Udekwu AO, Simmons RL. Hemorrhagic shock. Curr Probl Surg 1995; 32:925-1002.
9. Fong Y, Moldawer LL, Shires GT, Lowry SF. The biologic characteristics of cytokines and their implication in surgical injury. Surg Gynecol Obstet 1990; 170:363-378.
10. Maejima K, Deitch EA, Berg RD. Bacterial translocation from the gastrointestinal tracts of rats receiving thermal injury. Infect Immun 1984; 43:6-10.
11. Xu D, Lu Q, Guillory D, Cruz N, Berg R, Deitch EA. Mechanisms of endotoxin-induced intestinal injury in a hyperdynamic model of sepsis. J Trauma 1993; 34:676-682.
12. Deitch EA, Morrison J, Berg R, Specian RD. Effect of hemorrhagic shock on bacterial translocation, intestinal morphology and intestinal permeability in conventional and antibiotic decontaminated rats. Crit Care Med 1990; 18:529-536.
13. Deitch EA. Intestinal permeability is increased in burn patients shortly after injury. Surgery 1990; 107:411-416.
14. O'Dwyer ST, Mitchie HR, Ziegler TR, Revhaug A, Smith RJ, Wilmore DW. A single dose of endotoxin increases intestinal permeability in humans. Arch Surg 1988; 123:1459-1464.
15. Rush BF, Sori AJ, Murphy TF, Smith S, Flanagan JJ, Machiedo GW. Endotoxemia and bacteremia during hemorrhagic shock. The link between trauma and sepsis? Ann Surg 1988; 207:549-554.
16. Moore FA, Moore EE, Poggetti R, et al. Gut bacterial translocation via the portal vein: a clinical perspective with major torso trauma. J Trauma 1991; 31:629-638.
17. Peitzman AB, Udekwu AO, Ochoa J, Smith S. Bacterial translocation in trauma patients. J Trauma 1991; 31:1083-1087.
18. Schmelmg DJ, Caty MG, Oldham KT, Guice KS, Hinshaw DB. Evidence for neutrophil-related acute lung injury after intestinal ischemia-reperfusion. Surgery 1989; 106:195-202.
19. Poggetti RS, Moore FA, Moore EE, Koike K, Banerjee A. A simultaneous liver and lung injury following gut ischemia is mediated by xanthine oxidase. J Trauma 1992; 32:723-728.
20. Gerkin TM, Oldham KT, Guice KS, Hinshaw DB, Ryan US. Intestinal ischemia-reperfusion injury causes pulmonary endothelial cell ATP depletion. Ann Surg 1993; 217:48-56.
21. Baker JW, Deitch EA, Ma L, Berg RD, Specian RD. Hemorrhagic shock induces bacterial translocation from the gut. J Trauma 1988; 28:896-906.
22. Deitch EA, Bridges B, Baker J, et al. Hemorrhagic shock-induced bacterial translocation is reduced by xanthine oxidase inhibition or inactivation. Surgery 1988; 104:191-198.
23. Patterson CE, Rhoades RA, Garcia JGN. Evans blue dye as a marker of albumin clearance in cultured endothelial monolayer and isolated lung. J Appl Physiol 1992; 72:865-873.
24. Cohen JJ. Overview: mechanisms of apoptosis. Immunol Today 1993; 14:126-130.
25. Anderson BO, Brown JM, Shanley PF, Benserd DD, Harken AH. Marginating neutrophils are reversibly adherent to normal lung endothelium. Surgery 1991; 109:51-61.
26. Allan G, Bhattacherjee P, Brook CD, Read NG, Parke AJ. Myeloperoxidase activity as a quantitative marker of polymorphonuclear leukocyte accumulation into an experimental myocardial infarct - the effect of ibuprofen on infarct size and polymorphonuclear leukocyte accumulation. J Cardiovasc Pharmacol 1985; 7:1154-1160.
27. Koike K, Moore EE, Moore FA, Read RA, Carl VS, Banerjee A. Gut ischemia/reperfusion produces lung injury independent of endotoxin. Crit Care Med 1994; 22:1438-1444.
28. Koike K, Moore EE, Moore FA, Franciose RJ, Fontes B, Kim FJ. CD1 1b blockade prevents lung injury despite neurophil priming after gut ischemia/reperfusion. J Trauma 1995; 39:23-27.
29. Nagura H, Sumi Y. Immunological functions of the gut - role of the mucosal immune system. Toxicol Pathol 1988; 16:154-164.
30. Simpson R, Alon R, Kobzik L, Valeri CR, Shepro D, Hechtman HB. Neutrophil- and nonneutrophil-mediated injury in intestinal ischemia-reperfusion. Ann Surg 1993; 218:444-454.
31. Koike K, Moore EE, Moore FA, Kim FJW, Carl VS, Banerjee A. Gut phospholipase A2 mediates neutrophil priming and lung injury after mesenteric ischemia-reperfusion. Am J Physiol 1995; 268:G397-G403.
32. Deitch EA. Bacterial translocation of the gut flora. J Trauma 1990; 30:184-189.
33. Olofsson P, Nylander G, Olsson P. Endotoxin transport routes and kinetics in intestinal ischemia. Acta Chir Scand 1985; 151:635-639.
34. Olofsson P, Nylander G, Olsson P. Endotoxin routes of transport in experimental peritonitis. Am J Surg 1986; 151:443-446.
35. Gans H, Matsumoto K. The escape of endotoxin from the intestine. Surg Gynecol Obstet 1974; 139:395-402.
36. Braithwaite CEM, Ross SE, Nagele R, Mure AJ, O'Malley KF, Garcia-Perez FA. Bacterial translocation occurs in humans after traumatic injury: evidence using immunofluorescence. J Trauma 1993; 34:586-590.
37. Reed LL, Martin M, Manglano R, Newman B, Kocka F, Barrett J. Bacterial translocation following abdominal trauma in humans. Circ Shock 1994; 42:1-6.