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Volumn 29, Issue 1, 2010, Pages 91-98

Phytocannabinoids, CNS cells and development: A dead issue?

Author keywords

Cell fate; CNS cell; Development; Marijuana; Phytocannabinoid

Indexed keywords

CANNABINOID; CANNABIS;

EID: 77149177641     PISSN: 09595236     EISSN: 14653362     Source Type: Journal    
DOI: 10.1111/j.1465-3362.2009.00102.x     Document Type: Review
Times cited : (21)

References (100)
  • 1
    • 0025325535 scopus 로고
    • Structure of a cannabinoid receptor and functional expression of the cloned cDNA
    • Matsuda LA, Lolait SJ, Brownstein MJ, Young AC, Bonner TI. Structure of a cannabinoid receptor and functional expression of the cloned cDNA. Nature 1990;346:561-4.
    • (1990) Nature , vol.346 , pp. 561-564
    • Matsuda, L.A.1    Lolait, S.J.2    Brownstein, M.J.3    Young, A.C.4    Bonner, T.I.5
  • 2
    • 0027515373 scopus 로고
    • Molecular characterization of a peripheral receptor for cannabinoids
    • Munro S, Thomas KL, Abu-Shaar M. Molecular characterization of a peripheral receptor for cannabinoids. Nature 1993;365:61-5.
    • (1993) Nature , vol.365 , pp. 61-65
    • Munro, S.1    Thomas, K.L.2    Abu-Shaar, M.3
  • 4
    • 35648959293 scopus 로고    scopus 로고
    • The novel endocannabinoid receptor GPR55 is activated by atypical cannabinoids but does not mediate their vasodilator effects
    • Johns DG, Behm DJ, Walker DJ, et al. The novel endocannabinoid receptor GPR55 is activated by atypical cannabinoids but does not mediate their vasodilator effects. Br J Pharmacol 2007;152:825-31.
    • (2007) Br J Pharmacol , vol.152 , pp. 825-831
    • Johns, D.G.1    Behm, D.J.2    Walker, D.J.3
  • 5
    • 0035801320 scopus 로고    scopus 로고
    • Novel cannabinoidsensitive receptor mediates inhibition of glutamatergic synaptic transmission in the hippocampus
    • Hajos N, Ledent C, Freund TF. Novel cannabinoidsensitive receptor mediates inhibition of glutamatergic synaptic transmission in the hippocampus. Neuroscience 2001;106:1-4.
    • (2001) Neuroscience , vol.106 , pp. 1-4
    • Hajos, N.1    Ledent, C.2    Freund, T.F.3
  • 6
    • 0038845604 scopus 로고    scopus 로고
    • Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors
    • Jarai Z, Wagner JA, Varga K, et al. Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors. Proc Natl Acad Sci U S A 1999;96:14136-41.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 14136-14141
    • Jarai, Z.1    Wagner, J.A.2    Varga, K.3
  • 7
    • 33947489961 scopus 로고
    • Isolation, structure and partial synthesis of an active constituent of hashish
    • Gaoni Y, Mechoulam R. Isolation, structure and partial synthesis of an active constituent of hashish. J Am Chem Soc 1964;86:1646-7.
    • (1964) J Am Chem Soc , vol.86 , pp. 1646-1647
    • Gaoni, Y.1    Mechoulam, R.2
  • 8
    • 18444376760 scopus 로고    scopus 로고
    • International Union of Pharmacology XXVII. Classification of cannabinoid receptors
    • Howlett AC, Barth F, Bonner TI, et al. International Union of Pharmacology. XXVII. Classification of cannabinoid receptors. Pharmacol Rev 2002;54:161-202.
    • (2002) Pharmacol Rev , vol.54 , pp. 161-202
    • Howlett, A.C.1    Barth, F.2    Bonner, T.I.3
  • 10
    • 0014351938 scopus 로고
    • Hashish components Photochemical production of cannabicyclol from cannabichromene
    • Crombie L, Ponsford R, Shani A, Yagnitinsky B, Mechoulam R. Hashish components. Photochemical production of cannabicyclol from cannabichromene. Tetrahedron Lett 1968;55:5771-2.
    • (1968) Tetrahedron Lett , vol.55 , pp. 5771-5772
    • Crombie, L.1    Ponsford, R.2    Shani, A.3    Yagnitinsky, B.4    Mechoulam, R.5
  • 11
    • 0032983195 scopus 로고    scopus 로고
    • Delta 9-tetrahydrocannabivarin (delta 9-THCV) as a marker for the ingestion of cannabis versus Marinol
    • ElSohly MA, Feng S, Murphy TP, et al. Delta 9-tetrahydrocannabivarin (delta 9-THCV) as a marker for the ingestion of cannabis versus Marinol. J Anal Toxicol 1999;23:222-4.
    • (1999) J Anal Toxicol , vol.23 , pp. 222-224
    • ElSohly, M.A.1    Feng, S.2    Murphy, T.P.3
  • 13
    • 4043055159 scopus 로고    scopus 로고
    • The good and the bad effects of (-) transdelta-9-tetrahydrocannabinol (Delta 9-THC) on humans
    • Carlini EA. The good and the bad effects of (-) transdelta-9-tetrahydrocannabinol (Delta 9-THC) on humans. Toxicon 2004;44:461-7.
    • (2004) Toxicon , vol.44 , pp. 461-467
    • Carlini, E.A.1
  • 14
    • 0034879041 scopus 로고    scopus 로고
    • Antiemetic efficacy of smoked marijuana: subjective and behavioral effects on nausea induced by syrup of ipecac
    • Soderpalm AH, Schuster A, de Wit H. Antiemetic efficacy of smoked marijuana: subjective and behavioral effects on nausea induced by syrup of ipecac. Pharmacol Biochem Behav 2001;69:343-50.
    • (2001) Pharmacol Biochem Behav , vol.69 , pp. 343-350
    • Soderpalm, A.H.1    Schuster, A.2    de Wit, H.3
  • 15
    • 0022461256 scopus 로고
    • Antianxiety effect of cannabis: involvement of central benzodiazepine receptors
    • Sethi BB, et al. Antianxiety effect of cannabis: involvement of central benzodiazepine receptors. Biol Psychiatry 1986;21:3-10.
    • (1986) Biol Psychiatry , vol.21 , pp. 3-10
    • Sethi, B.B.1
  • 16
    • 4344582253 scopus 로고    scopus 로고
    • Do cannabis-based medicinal extracts have general or specific effects on symptoms in multiple sclerosis? A double-blind, randomized, placebo-controlled study on 160 patients
    • Wade DT, Makela P, Robson P, House H, Bateman C. Do cannabis-based medicinal extracts have general or specific effects on symptoms in multiple sclerosis? A double-blind, randomized, placebo-controlled study on 160 patients. Mult Scler 2004;10:434-41.
    • (2004) Mult Scler , vol.10 , pp. 434-441
    • Wade, D.T.1    Makela, P.2    Robson, P.3    House, H.4    Bateman, C.5
  • 17
    • 9244223576 scopus 로고    scopus 로고
    • Efficacy of two cannabis based medicinal extracts for relief of central neuropathic pain from brachial plexus avulsion: results of a randomised controlled trial
    • Berman JS, Symonds C, Birch R. Efficacy of two cannabis based medicinal extracts for relief of central neuropathic pain from brachial plexus avulsion: results of a randomised controlled trial. Pain 2004;112:299-306.
    • (2004) Pain , vol.112 , pp. 299-306
    • Berman, J.S.1    Symonds, C.2    Birch, R.3
  • 18
    • 34248219556 scopus 로고    scopus 로고
    • Cannabinoids for the treatment of inflammation
    • Ashton JC. Cannabinoids for the treatment of inflammation. Curr Opin Investig Drugs 2007;8:373-84.
    • (2007) Curr Opin Investig Drugs , vol.8 , pp. 373-384
    • Ashton, J.C.1
  • 19
    • 1542510624 scopus 로고    scopus 로고
    • Cannabinoids induce cancer cell proliferation via tumor necrosis factor alphaconverting enzyme (TACE/ADAM17)-mediated transactivation of the epidermal growth factor receptor
    • Hart S, Fischer OM, Ullrich A. Cannabinoids induce cancer cell proliferation via tumor necrosis factor alphaconverting enzyme (TACE/ADAM17)-mediated transactivation of the epidermal growth factor receptor. Cancer Res 2004;64:1943-50.
    • (2004) Cancer Res , vol.64 , pp. 1943-1950
    • Hart, S.1    Fischer, O.M.2    Ullrich, A.3
  • 20
    • 17344380844 scopus 로고    scopus 로고
    • Anti-tumoral action of cannabinoids: involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation
    • Galve-Roperh I, Sanchez C, Cortes ML, del Pulgar TG, Izquierdo M, Guzman M. Anti-tumoral action of cannabinoids: involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation. Nat Med 2000;6:313-19.
    • (2000) Nat Med , vol.6 , pp. 313-319
    • Galve-Roperh, I.1    Sanchez, C.2    Cortes, M.L.3    del Pulgar, T.G.4    Izquierdo, M.5    Guzman, M.6
  • 21
    • 0032527129 scopus 로고    scopus 로고
    • Hippocampal neurotoxicity of Delta9-tetrahydrocannabinol
    • Chan GC, Hinds TR, Impey S, Storm DR. Hippocampal neurotoxicity of Delta9-tetrahydrocannabinol. J Neurosci 1998;18:5322-32.
    • (1998) J Neurosci , vol.18 , pp. 5322-5332
    • Chan, G.C.1    Hinds, T.R.2    Impey, S.3    Storm, D.R.4
  • 22
    • 17644431844 scopus 로고    scopus 로고
    • Cannabinoids inhibit the formation of new synapses between hippocampal neurons in culture
    • Kim D, Thayer SA. Cannabinoids inhibit the formation of new synapses between hippocampal neurons in culture. J Neurosci 2001;21:RC146.
    • (2001) J Neurosci , vol.21
    • Kim, D.1    Thayer, S.A.2
  • 23
    • 0035049233 scopus 로고    scopus 로고
    • Tetrahydrocannabinol-induced apoptosis of cultured cortical neurones is associated with cytochrome c release and caspase-3 activation
    • Campbell VA. Tetrahydrocannabinol-induced apoptosis of cultured cortical neurones is associated with cytochrome c release and caspase-3 activation. Neuropharmacology 2001;40:702-9.
    • (2001) Neuropharmacology , vol.40 , pp. 702-709
    • Campbell, V.A.1
  • 24
    • 0035930446 scopus 로고    scopus 로고
    • Delta 9-tetrahydrocannabinol induces the apoptotic pathway in cultured cortical neurones via activation of the CB1 receptor
    • Downer E, Boland B, Fogarty M, Campbell V. Delta 9-tetrahydrocannabinol induces the apoptotic pathway in cultured cortical neurones via activation of the CB1 receptor. Neuroreport 2001;12:3973-8.
    • (2001) Neuroreport , vol.12 , pp. 3973-3978
    • Downer, E.1    Boland, B.2    Fogarty, M.3    Campbell, V.4
  • 25
    • 23944437209 scopus 로고    scopus 로고
    • Cannabinoids selectively inhibit proliferation and induce death of cultured human glioblastoma multiforme cells
    • McAllister SD, Chan C, Taft RJ, et al. Cannabinoids selectively inhibit proliferation and induce death of cultured human glioblastoma multiforme cells. J Neurooncol 2005;74:31-40.
    • (2005) J Neurooncol , vol.74 , pp. 31-40
    • McAllister, S.D.1    Chan, C.2    Taft, R.J.3
  • 26
    • 33645763253 scopus 로고    scopus 로고
    • The stressregulated protein p8 mediates cannabinoid-induced apoptosis of tumor cells
    • Carracedo A, Lorente M, Egia A, et al. The stressregulated protein p8 mediates cannabinoid-induced apoptosis of tumor cells. Cancer Cell 2006;9:301-12.
    • (2006) Cancer Cell , vol.9 , pp. 301-312
    • Carracedo, A.1    Lorente, M.2    Egia, A.3
  • 27
    • 0032493197 scopus 로고    scopus 로고
    • Cannabidiol and (-)Delta9-tetrahydrocannabinol are neuroprotective antioxidants
    • Hampson AJ, Grimaldi M, Axelrod J, Wink D. Cannabidiol and (-)Delta9-tetrahydrocannabinol are neuroprotective antioxidants. Proc Natl Acad Sci U S A 1998;95:8268-73.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 8268-8273
    • Hampson, A.J.1    Grimaldi, M.2    Axelrod, J.3    Wink, D.4
  • 28
    • 1842510018 scopus 로고    scopus 로고
    • Neuroprotective effect of cannabidiol, a nonpsychoactive component from Cannabis sativa, on betaamyloid-induced toxicity in PC12 cells
    • Iuvone T, Esposito G, Esposito R, Santamaria R, Di Rosa M, Izzo AA. Neuroprotective effect of cannabidiol, a nonpsychoactive component from Cannabis sativa, on betaamyloid-induced toxicity in PC12 cells. J Neurochem 2004;89:134-41.
    • (2004) J Neurochem , vol.89 , pp. 134-141
    • Iuvone, T.1    Esposito, G.2    Esposito, R.3    Santamaria, R.4    Di Rosa, M.5    Izzo, A.A.6
  • 29
    • 33846066404 scopus 로고    scopus 로고
    • Delta9-tetrahydrocannabinol protects hippocampal neurons from excitotoxicity
    • Gilbert GL, Kim HJ, Waataja JJ, Thayer SA. Delta9-tetrahydrocannabinol protects hippocampal neurons from excitotoxicity. Brain Res 2007;1128:61-9.
    • (2007) Brain Res , vol.1128 , pp. 61-69
    • Gilbert, G.L.1    Kim, H.J.2    Waataja, J.J.3    Thayer, S.A.4
  • 30
    • 0035979606 scopus 로고    scopus 로고
    • Activation of the CB1 cannabinoid receptor protects cultured mouse spinal neurons against excitotoxicity
    • Abood ME, Rizvi G, Sallapudi N, McAllister SD. Activation of the CB1 cannabinoid receptor protects cultured mouse spinal neurons against excitotoxicity. Neurosci Lett 2001;309:197-201.
    • (2001) Neurosci Lett , vol.309 , pp. 197-201
    • Abood, M.E.1    Rizvi, G.2    Sallapudi, N.3    McAllister, S.D.4
  • 31
    • 17444370570 scopus 로고    scopus 로고
    • Cannabinoids provide neuroprotection against 6-hydroxydopamine toxicity in vivo and in vitro: relevance to Parkinson's disease
    • Lastres-Becker I, Molina-Holgado F, Ramos JA, Mechoulam R, Fernandez-Ruiz J. Cannabinoids provide neuroprotection against 6-hydroxydopamine toxicity in vivo and in vitro: relevance to Parkinson's disease. Neurobiol Dis 2005;19:96-107.
    • (2005) Neurobiol Dis , vol.19 , pp. 96-107
    • Lastres-Becker, I.1    Molina-Holgado, F.2    Ramos, J.A.3    Mechoulam, R.4    Fernandez-Ruiz, J.5
  • 32
    • 0035437865 scopus 로고    scopus 로고
    • Neuroprotection by Delta9-tetrahydrocannabinol, the main active compound in marijuana, against ouabain-induced in vivo excitotoxicity
    • van der Stelt M, Veldhuis WB, Bar PR, Veldink GA, Vliegenthart JF, Nicolay K. Neuroprotection by Delta9-tetrahydrocannabinol, the main active compound in marijuana, against ouabain-induced in vivo excitotoxicity. J Neurosci 2001;21:6475-9.
    • (2001) J Neurosci , vol.21 , pp. 6475-6479
    • van der Stelt, M.1    Veldhuis, W.B.2    Bar, P.R.3    Veldink, G.A.4    Vliegenthart, J.F.5    Nicolay, K.6
  • 33
    • 34547870158 scopus 로고    scopus 로고
    • Delayed treatment with cannabidiol has a cerebroprotective action via a cannabinoid receptor-independent myeloperoxidaseinhibiting mechanism
    • Hayakawa K, Mishima K, Nozako M, et al. Delayed treatment with cannabidiol has a cerebroprotective action via a cannabinoid receptor-independent myeloperoxidaseinhibiting mechanism. J Neurochem 2007;102:1488-96.
    • (2007) J Neurochem , vol.102 , pp. 1488-1496
    • Hayakawa, K.1    Mishima, K.2    Nozako, M.3
  • 34
    • 34848875379 scopus 로고    scopus 로고
    • A comparison of the apoptotic effect of Delta(9)-tetrahydrocannabinol in the neonatal and adult rat cerebral cortex
    • Downer EJ, Gowran A, Campbell VA. A comparison of the apoptotic effect of Delta(9)-tetrahydrocannabinol in the neonatal and adult rat cerebral cortex. Brain Res 2007; 1175:39-47.
    • (2007) Brain Res , vol.1175 , pp. 39-47
    • Downer, E.J.1    Gowran, A.2    Campbell, V.A.3
  • 35
    • 0343878783 scopus 로고    scopus 로고
    • Neuronal and astroglial response to pre- and perinatal exposure to delta-9-tetra-hydrocannabinol in the rat substantia nigra
    • Suarez I, Bodega G, Ramos JA, Fernandez-Ruiz JJ, Fernandez B. Neuronal and astroglial response to pre- and perinatal exposure to delta-9-tetra-hydrocannabinol in the rat substantia nigra. Dev Neurosci 2000;22:253-63.
    • (2000) Dev Neurosci , vol.22 , pp. 253-263
    • Suarez, I.1    Bodega, G.2    Ramos, J.A.3    Fernandez-Ruiz, J.J.4    Fernandez, B.5
  • 36
    • 42949156303 scopus 로고    scopus 로고
    • Volumetric MRI study of brain in children with intrauterine exposure to cocaine, alcohol, tobacco, and marijuana
    • Rivkin MJ, Davis PE, Lemaster JL, et al. Volumetric MRI study of brain in children with intrauterine exposure to cocaine, alcohol, tobacco, and marijuana. Pediatrics 2008;121:741-50.
    • (2008) Pediatrics , vol.121 , pp. 741-750
    • Rivkin, M.J.1    Davis, P.E.2    Lemaster, J.L.3
  • 37
    • 0033838024 scopus 로고    scopus 로고
    • Brain morphological changes and early marijuana use: a magnetic resonance and positron emission tomography study
    • Wilson W, Mathew R, Turkington T, Hawk T, Coleman RE, Provenzale J. Brain morphological changes and early marijuana use: a magnetic resonance and positron emission tomography study. J Addict Dis 2000;19:1-22.
    • (2000) J Addict Dis , vol.19 , pp. 1-22
    • Wilson, W.1    Mathew, R.2    Turkington, T.3    Hawk, T.4    Coleman, R.E.5    Provenzale, J.6
  • 38
    • 84941817498 scopus 로고
    • Absence of cerebral atrophy in chronic cannabis users Evaluation by computerized transaxial tomography
    • Co BT, Goodwin DW, Gado M, Mikhael M, Hill SY. Absence of cerebral atrophy in chronic cannabis users. Evaluation by computerized transaxial tomography. JAMA 1977;237:1229-30.
    • (1977) JAMA , vol.237 , pp. 1229-1230
    • Co, B.T.1    Goodwin, D.W.2    Gado, M.3    Mikhael, M.4    Hill, S.Y.5
  • 39
    • 0020683652 scopus 로고
    • Neurological and neuroradiological examination of chronic cannabis smokers
    • Hannerz J, Hindmarsh T. Neurological and neuroradiological examination of chronic cannabis smokers. Ann Neurol 1983;13:207-10.
    • (1983) Ann Neurol , vol.13 , pp. 207-210
    • Hannerz, J.1    Hindmarsh, T.2
  • 40
    • 13444256351 scopus 로고    scopus 로고
    • Lack of hippocampal volume change in long-term heavy cannabis users
    • Tzilos GK, Cintron CB, Wood JB, et al. Lack of hippocampal volume change in long-term heavy cannabis users. Am J Addict 2005;14:64-72.
    • (2005) Am J Addict , vol.14 , pp. 64-72
    • Tzilos, G.K.1    Cintron, C.B.2    Wood, J.B.3
  • 41
    • 33746649501 scopus 로고    scopus 로고
    • A preliminary DTI study showing no brain structural change associated with adolescent cannabis use
    • Delisi LE, Bertisch HC, Szulc K, et al. A preliminary DTI study showing no brain structural change associated with adolescent cannabis use. Harm Reduct J 2006;3:17.
    • (2006) Harm Reduct J , vol.3 , pp. 17
    • Delisi, L.E.1    Bertisch, H.C.2    Szulc, K.3
  • 42
    • 0034002710 scopus 로고    scopus 로고
    • Effects of frequent marijuana use on brain tissue volume and composition
    • Block RI, O'Leary DS, Ehrhardt JC, et al. Effects of frequent marijuana use on brain tissue volume and composition. Neuroreport 2000;11:491-6.
    • (2000) Neuroreport , vol.11 , pp. 491-496
    • Block, R.I.1    O'Leary, D.S.2    Ehrhardt, J.C.3
  • 45
    • 44649187915 scopus 로고    scopus 로고
    • Regional brain abnormalities associated with long-term heavy cannabis use
    • Yucel M, Solowij N, Respondek C, et al. Regional brain abnormalities associated with long-term heavy cannabis use. Arch Gen Psychiatry 2008;65:694-701.
    • (2008) Arch Gen Psychiatry , vol.65 , pp. 694-701
    • Yucel, M.1    Solowij, N.2    Respondek, C.3
  • 46
    • 44449109468 scopus 로고    scopus 로고
    • Corpus callosum damage in heavy marijuana use: preliminary evidence from diffusion tensor tractography and tract-based spatial statistics
    • Arnone D, Barrick TR, Chengappa S, Mackay CE, Clark CA, Abou-Saleh MT. Corpus callosum damage in heavy marijuana use: preliminary evidence from diffusion tensor tractography and tract-based spatial statistics. Neuroimage 2008;41:1067-74.
    • (2008) Neuroimage , vol.41 , pp. 1067-1074
    • Arnone, D.1    Barrick, T.R.2    Chengappa, S.3    Mackay, C.E.4    Clark, C.A.5    Abou-Saleh, M.T.6
  • 47
    • 0023619607 scopus 로고
    • Morphometric studies of the rat hippocampus following chronic delta-9-tetrahydrocannabinol (THC)
    • Scallet AC, Uemura E, Andrews A, et al. Morphometric studies of the rat hippocampus following chronic delta-9-tetrahydrocannabinol (THC). Brain Res 1987;436:193-8.
    • (1987) Brain Res , vol.436 , pp. 193-198
    • Scallet, A.C.1    Uemura, E.2    Andrews, A.3
  • 48
    • 0025720576 scopus 로고
    • Neurotoxicology of cannabis and THC: a review of chronic exposure studies in animals
    • Scallet AC. Neurotoxicology of cannabis and THC: a review of chronic exposure studies in animals. Pharmacol Biochem Behav 1991;40:671-6.
    • (1991) Pharmacol Biochem Behav , vol.40 , pp. 671-676
    • Scallet, A.C.1
  • 49
    • 0022472739 scopus 로고
    • Health aspects of cannabis
    • Hollister LE. Health aspects of cannabis. Pharmacol Rev 1986;38:1-20.
    • (1986) Pharmacol Rev , vol.38 , pp. 1-20
    • Hollister, L.E.1
  • 51
    • 0033198288 scopus 로고    scopus 로고
    • Analysis of cannabinoid receptor binding and mRNA expression and endogenous cannabinoid contents in the developing rat brain during late gestation and early postnatal period
    • Berrendero F, Sepe N, Ramos JA, Di Marzo V, Fernandez-Ruiz JJ. Analysis of cannabinoid receptor binding and mRNA expression and endogenous cannabinoid contents in the developing rat brain during late gestation and early postnatal period. Synapse 1999;33:181-91.
    • (1999) Synapse , vol.33 , pp. 181-191
    • Berrendero, F.1    Sepe, N.2    Ramos, J.A.3    Di Marzo, V.4    Fernandez-Ruiz, J.J.5
  • 52
    • 0031715388 scopus 로고    scopus 로고
    • Localization of mRNA expression and activation of signal transduction mechanisms for cannabinoid receptor in rat brain during fetal development
    • Berrendero F, Garcia-Gil L, Hernandez ML, et al. Localization of mRNA expression and activation of signal transduction mechanisms for cannabinoid receptor in rat brain during fetal development. Development 1998;125:3179-88.
    • (1998) Development , vol.125 , pp. 3179-3188
    • Berrendero, F.1    Garcia-Gil, L.2    Hernandez, M.L.3
  • 53
    • 0030944213 scopus 로고    scopus 로고
    • Atypical location of cannabinoid receptors in white matter areas during rat brain development
    • Romero J, Garcia-Palomero E, Berrendero F, et al. Atypical location of cannabinoid receptors in white matter areas during rat brain development. Synapse 1997;26:317-23.
    • (1997) Synapse , vol.26 , pp. 317-323
    • Romero, J.1    Garcia-Palomero, E.2    Berrendero, F.3
  • 54
    • 42249098694 scopus 로고    scopus 로고
    • Endocannabinoid functions controlling neuronal specification during brain development
    • Harkany T, Keimpema E, Barabas K, Mulder J. Endocannabinoid functions controlling neuronal specification during brain development. Mol Cell Endocrinol 2008; 286(1-2 Suppl 1):S84-90.
    • (2008) Mol Cell Endocrinol , vol.286 , Issue.1-2 SUPPL 1
    • Harkany, T.1    Keimpema, E.2    Barabas, K.3    Mulder, J.4
  • 55
    • 34548696608 scopus 로고    scopus 로고
    • Cannabinoids modulate Olig2 and polysialylated neural cell adhesion molecule expression in the subventricular zone of post-natal rats through cannabinoid receptor 1 and cannabinoid receptor 2
    • Arevalo-Martin A, Garcia-Ovejero D, Rubio-Araiz A, Gomez O, Molina-Holgado F, Molina-Holgado E. Cannabinoids modulate Olig2 and polysialylated neural cell adhesion molecule expression in the subventricular zone of post-natal rats through cannabinoid receptor 1 and cannabinoid receptor 2. Eur J Neurosci 2007;26:1548-59.
    • (2007) Eur J Neurosci , vol.26 , pp. 1548-1559
    • Arevalo-Martin, A.1    Garcia-Ovejero, D.2    Rubio-Araiz, A.3    Gomez, O.4    Molina-Holgado, F.5    Molina-Holgado, E.6
  • 56
    • 34047156445 scopus 로고    scopus 로고
    • The endocannabinoid system and neurogenesis in health and disease
    • Galve-Roperh I, Aguado T, Palazuelos J, Guzman M. The endocannabinoid system and neurogenesis in health and disease. Neuroscientist 2007;13:109-14.
    • (2007) Neuroscientist , vol.13 , pp. 109-114
    • Galve-Roperh, I.1    Aguado, T.2    Palazuelos, J.3    Guzman, M.4
  • 57
    • 34249978494 scopus 로고    scopus 로고
    • Hardwiring the brain: endocannabinoids shape neuronal connectivity
    • Berghuis P, Rajnicek AM, Morozov YM, et al. Hardwiring the brain: endocannabinoids shape neuronal connectivity. Science 2007;316:1212-16.
    • (2007) Science , vol.316 , pp. 1212-1216
    • Berghuis, P.1    Rajnicek, A.M.2    Morozov, Y.M.3
  • 58
    • 0024505292 scopus 로고
    • Plasma concentrations of delta-9-tetrahydrocannabinol in dams and fetuses following acute or multiple prenatal dosing in rats
    • Hutchings DE, Martin BR, Gamagaris Z, Miller N, Fico T. Plasma concentrations of delta-9-tetrahydrocannabinol in dams and fetuses following acute or multiple prenatal dosing in rats. Life Sci 1989;44:697-701.
    • (1989) Life Sci , vol.44 , pp. 697-701
    • Hutchings, D.E.1    Martin, B.R.2    Gamagaris, Z.3    Miller, N.4    Fico, T.5
  • 59
    • 0142184948 scopus 로고    scopus 로고
    • Tetrahydrocannabinol-induced neurotoxicity depends on CB1 receptor-mediated c-Jun N-terminal kinase activation in cultured cortical neurons
    • Downer EJ, Fogarty MP, Campbell VA. Tetrahydrocannabinol-induced neurotoxicity depends on CB1 receptor-mediated c-Jun N-terminal kinase activation in cultured cortical neurons. Br J Pharmacol 2003; 140:547-57.
    • (2003) Br J Pharmacol , vol.140 , pp. 547-557
    • Downer, E.J.1    Fogarty, M.P.2    Campbell, V.A.3
  • 60
    • 34250687550 scopus 로고    scopus 로고
    • The tumour suppressor protein, p53, is involved in the activation of the apoptotic cascade by Delta9-tetrahydrocannabinol in cultured cortical neurons
    • Downer EJ, Gowran A, Murphy AC, Campbell VA. The tumour suppressor protein, p53, is involved in the activation of the apoptotic cascade by Delta9-tetrahydrocannabinol in cultured cortical neurons. Eur J Pharmacol 2007;564:57-65.
    • (2007) Eur J Pharmacol , vol.564 , pp. 57-65
    • Downer, E.J.1    Gowran, A.2    Murphy, A.C.3    Campbell, V.A.4
  • 61
    • 0030940056 scopus 로고    scopus 로고
    • Receptor mediation in cannabinoid stimulated arachidonic acid mobilization and anandamide synthesis
    • Hunter SA, Burstein SH. Receptor mediation in cannabinoid stimulated arachidonic acid mobilization and anandamide synthesis. Life Sci 1997;60:1563-73.
    • (1997) Life Sci , vol.60 , pp. 1563-1573
    • Hunter, S.A.1    Burstein, S.H.2
  • 62
    • 0021320468 scopus 로고
    • Effects of delta 9-THC on pregnancy and offspring in rats
    • Abel EL. Effects of delta 9-THC on pregnancy and offspring in rats. Neurobehav Toxicol Teratol 1984;6:29-32.
    • (1984) Neurobehav Toxicol Teratol , vol.6 , pp. 29-32
    • Abel, E.L.1
  • 63
    • 7544222031 scopus 로고    scopus 로고
    • Prenatal cannabinoid exposure downregulates glutamate transporter expressions (GLAST and EAAC1) in the rat cerebellum
    • Suarez I, Bodega G, Rubio M, Fernandez-Ruiz JJ, Ramos JA, Fernandez B. Prenatal cannabinoid exposure downregulates glutamate transporter expressions (GLAST and EAAC1) in the rat cerebellum. Dev Neurosci 2004;26:45-53.
    • (2004) Dev Neurosci , vol.26 , pp. 45-53
    • Suarez, I.1    Bodega, G.2    Rubio, M.3    Fernandez-Ruiz, J.J.4    Ramos, J.A.5    Fernandez, B.6
  • 64
    • 44149112787 scopus 로고    scopus 로고
    • Perinatal delta-9-tetrahydrocannabinol exposure disrupts social and open field behavior in adult male rats
    • Newsom RJ, Kelly SJ. Perinatal delta-9-tetrahydrocannabinol exposure disrupts social and open field behavior in adult male rats. Neurotoxicol Teratol 2008;30:213-19.
    • (2008) Neurotoxicol Teratol , vol.30 , pp. 213-219
    • Newsom, R.J.1    Kelly, S.J.2
  • 65
    • 0029670237 scopus 로고    scopus 로고
    • Perinatal cannabinoid exposure modifies the sociosexual approach behavior and the mesolimbic dopaminergic activity of adult male rats
    • NavarroM, de Miguel R, Rodriguez de Fonseca F, Ramos JA, Fernandez-Ruiz JJ. Perinatal cannabinoid exposure modifies the sociosexual approach behavior and the mesolimbic dopaminergic activity of adult male rats. Behav Brain Res 1996;75:91-8.
    • (1996) Behav Brain Res , vol.75 , pp. 91-98
    • Navarro, M.1    de Miguel, R.2    Rodriguez de Fonseca, F.3    Ramos, J.A.4    Fernandez-Ruiz, J.J.5
  • 67
    • 0015621781 scopus 로고
    • Radioactivity in suckled rats after giving 14 C-tetrahydrocannabinol to the mother
    • Jakubovic A, Hattori T, McGeer PL. Radioactivity in suckled rats after giving 14 C-tetrahydrocannabinol to the mother. Eur J Pharmacol 1973;22:221-3.
    • (1973) Eur J Pharmacol , vol.22 , pp. 221-223
    • Jakubovic, A.1    Hattori, T.2    McGeer, P.L.3
  • 68
    • 0026514427 scopus 로고
    • Comparisons between brain dopaminergic neurons of juvenile and aged rats: sex-related differences
    • Fernandez-Ruiz J, De Miguel R, Hernandez ML, Cebeira M, Ramos JA. Comparisons between brain dopaminergic neurons of juvenile and aged rats: sex-related differences. Mech Ageing Dev 1992;63:45-55.
    • (1992) Mech Ageing Dev , vol.63 , pp. 45-55
    • Fernandez-Ruiz, J.1    De Miguel, R.2    Hernandez, M.L.3    Cebeira, M.4    Ramos, J.A.5
  • 69
    • 0022526019 scopus 로고
    • Cannabinoid exposure: effects on development
    • Dalterio SL. Cannabinoid exposure: effects on development. Neurobehav Toxicol Teratol 1986;8:345-52.
    • (1986) Neurobehav Toxicol Teratol , vol.8 , pp. 345-352
    • Dalterio, S.L.1
  • 71
    • 0025163701 scopus 로고
    • Effect of early exposure to delta-9-tetrahydrocannabinol on the levels of opioid peptides, gonadotropin-releasing hormone and substance P in the adult male rat brain
    • Kumar AM, Haney M, Becker T, Thompson ML, Kream RM, Miczek K. Effect of early exposure to delta-9-tetrahydrocannabinol on the levels of opioid peptides, gonadotropin-releasing hormone and substance P in the adult male rat brain. Brain Res 1990;525:78-83.
    • (1990) Brain Res , vol.525 , pp. 78-83
    • Kumar, A.M.1    Haney, M.2    Becker, T.3    Thompson, M.L.4    Kream, R.M.5    Miczek, K.6
  • 72
    • 0036446407 scopus 로고    scopus 로고
    • Reduced glial fibrillary acidic protein and glutamine synthetase expression in astrocytes and Bergmann glial cells in the rat cerebellum caused by delta(9)-tetrahydrocannabinol administration during development
    • Suarez I, Bodega G, Fernandez-Ruiz JJ, Ramos JA, Rubio M, Fernandez B. Reduced glial fibrillary acidic protein and glutamine synthetase expression in astrocytes and Bergmann glial cells in the rat cerebellum caused by delta(9)-tetrahydrocannabinol administration during development. Dev Neurosci 2002;24:300-12.
    • (2002) Dev Neurosci , vol.24 , pp. 300-312
    • Suarez, I.1    Bodega, G.2    Fernandez-Ruiz, J.J.3    Ramos, J.A.4    Rubio, M.5    Fernandez, B.6
  • 73
    • 0037077803 scopus 로고    scopus 로고
    • Drug abuse's smallest victims: in utero drug exposure
    • Huestis MA, Choo RE. Drug abuse's smallest victims: in utero drug exposure. Forensic Sci Int 2002;128:20-30.
    • (2002) Forensic Sci Int , vol.128 , pp. 20-30
    • Huestis, M.A.1    Choo, R.E.2
  • 74
    • 0029017891 scopus 로고
    • The Ottawa Prenatal Prospective Study (OPPS): methodological issues and findings-it's easy to throw the baby out with the bath water
    • Fried PA. The Ottawa Prenatal Prospective Study (OPPS): methodological issues and findings-it's easy to throw the baby out with the bath water. Life Sci 1995; 56:2159-68.
    • (1995) Life Sci , vol.56 , pp. 2159-2168
    • Fried, P.A.1
  • 75
    • 0025289746 scopus 로고
    • Maternal marijuana use during lactation and infant development at one year
    • Astley SJ, Little RE. Maternal marijuana use during lactation and infant development at one year. Neurotoxicol Teratol 1990;12:161-8.
    • (1990) Neurotoxicol Teratol , vol.12 , pp. 161-168
    • Astley, S.J.1    Little, R.E.2
  • 76
    • 0035077403 scopus 로고    scopus 로고
    • A literature review of the consequences of prenatal marihuana exposure An emerging theme of a deficiency in aspects of executive function
    • Fried PA, Smith AM. A literature review of the consequences of prenatal marihuana exposure. An emerging theme of a deficiency in aspects of executive function. Neurotoxicol Teratol 2001;23:1-11.
    • (2001) Neurotoxicol Teratol , vol.23 , pp. 1-11
    • Fried, P.A.1    Smith, A.M.2
  • 77
    • 0025047001 scopus 로고
    • 36- and 48-month neurobehavioral follow-up of children prenatally exposed to marijuana, cigarettes, and alcohol
    • Fried PA, Watkinson B. 36- and 48-month neurobehavioral follow-up of children prenatally exposed to marijuana, cigarettes, and alcohol. J Dev Behav Pediatr 1990;11:49-58.
    • (1990) J Dev Behav Pediatr , vol.11 , pp. 49-58
    • Fried, P.A.1    Watkinson, B.2
  • 80
    • 20444368843 scopus 로고    scopus 로고
    • Prenatal marijuana exposure: effect on child depressive symptoms at ten years of age
    • Gray KA, Day NL, Leech S, Richardson GA. Prenatal marijuana exposure: effect on child depressive symptoms at ten years of age. Neurotoxicol Teratol 2005;27:439-48.
    • (2005) Neurotoxicol Teratol , vol.27 , pp. 439-448
    • Gray, K.A.1    Day, N.L.2    Leech, S.3    Richardson, G.A.4
  • 81
    • 33751196600 scopus 로고    scopus 로고
    • The effect of chronic peripubertal cannabinoid treatment on deficient object recognition memory in rats after neonatal mPFC lesion
    • Schneider M, Koch M. The effect of chronic peripubertal cannabinoid treatment on deficient object recognition memory in rats after neonatal mPFC lesion. Eur Neuropsychopharmacol 2007;17:180-6.
    • (2007) Eur Neuropsychopharmacol , vol.17 , pp. 180-186
    • Schneider, M.1    Koch, M.2
  • 82
    • 43749124806 scopus 로고    scopus 로고
    • Puberty as a highly vulnerable developmental period for the consequences of cannabis exposure
    • Schneider M. Puberty as a highly vulnerable developmental period for the consequences of cannabis exposure. Addict Biol 2008;13:253-63.
    • (2008) Addict Biol , vol.13 , pp. 253-263
    • Schneider, M.1
  • 83
    • 0023224067 scopus 로고
    • Acute delta 9-tetrahydrocannabinol exposure alters Ca2+ ATPase activity in neuroendocrine and gonadal tissues in mice
    • Dalterio SL, Bernard SA, Esquivel CR. Acute delta 9-tetrahydrocannabinol exposure alters Ca2+ ATPase activity in neuroendocrine and gonadal tissues in mice. Eur J Pharmacol 1987;137:91-100.
    • (1987) Eur J Pharmacol , vol.137 , pp. 91-100
    • Dalterio, S.L.1    Bernard, S.A.2    Esquivel, C.R.3
  • 84
    • 0021812737 scopus 로고
    • Residual effects of chronic cannabis treatment on behavior in mature rats
    • Stiglick A, Kalant H. Residual effects of chronic cannabis treatment on behavior in mature rats. Psychopharmacology (Berl) 1985;85:436-9.
    • (1985) Psychopharmacology (Berl) , vol.85 , pp. 436-439
    • Stiglick, A.1    Kalant, H.2
  • 86
    • 0032935782 scopus 로고    scopus 로고
    • Specific attentional dysfunction in adults following early start of cannabis use
    • Ehrenreich H, Rinn T, Kunert HJ, et al. Specific attentional dysfunction in adults following early start of cannabis use. Psychopharmacology (Berl) 1999;142:295-301.
    • (1999) Psychopharmacology (Berl) , vol.142 , pp. 295-301
    • Ehrenreich, H.1    Rinn, T.2    Kunert, H.J.3
  • 87
    • 0642338928 scopus 로고    scopus 로고
    • Chronic pubertal, but not adult chronic cannabinoid treatment impairs sensorimotor gating, recognition memory, and the performance in a progressive ratio task in adult rats
    • Schneider M, Koch M. Chronic pubertal, but not adult chronic cannabinoid treatment impairs sensorimotor gating, recognition memory, and the performance in a progressive ratio task in adult rats. Neuropsychopharmacology 2003;28:1760-9.
    • (2003) Neuropsychopharmacology , vol.28 , pp. 1760-1769
    • Schneider, M.1    Koch, M.2
  • 88
    • 20944446077 scopus 로고    scopus 로고
    • Moderation of the effect of adolescent-onset cannabis use on adult psychosis by a functional polymorphism in the catechol-Omethyltransferase gene: longitudinal evidence of a gene X environment interaction
    • Caspi A, Moffitt TE, Cannon M, et al. Moderation of the effect of adolescent-onset cannabis use on adult psychosis by a functional polymorphism in the catechol-Omethyltransferase gene: longitudinal evidence of a gene X environment interaction. Biol Psychiatry 2005;57:1117-27.
    • (2005) Biol Psychiatry , vol.57 , pp. 1117-1127
    • Caspi, A.1    Moffitt, T.E.2    Cannon, M.3
  • 89
    • 57749109837 scopus 로고    scopus 로고
    • Altered growth factor signaling pathways as the basis of aberrant stem cell maturation in schizophrenia
    • Kalkman HO. Altered growth factor signaling pathways as the basis of aberrant stem cell maturation in schizophrenia. Pharmacol Ther 2009;121:115-22.
    • (2009) Pharmacol Ther , vol.121 , pp. 115-122
    • Kalkman, H.O.1
  • 91
    • 0442307621 scopus 로고    scopus 로고
    • Causal association between cannabis and psychosis: examination of the evidence
    • Arseneault L, Cannon M, Witton J, Murray RM. Causal association between cannabis and psychosis: examination of the evidence. Br J Psychiatry 2004;184:110-17.
    • (2004) Br J Psychiatry , vol.184 , pp. 110-117
    • Arseneault, L.1    Cannon, M.2    Witton, J.3    Murray, R.M.4
  • 92
    • 33847020067 scopus 로고    scopus 로고
    • Cannabis and cognitive dysfunction: parallels with endophenotypes of schizophrenia?
    • Solowij N, Michie PT. Cannabis and cognitive dysfunction: parallels with endophenotypes of schizophrenia? J Psychiatry Neurosci 2007;32:30-52.
    • (2007) J Psychiatry Neurosci , vol.32 , pp. 30-52
    • Solowij, N.1    Michie, P.T.2
  • 93
    • 17744379225 scopus 로고    scopus 로고
    • Cannabis as a risk factor for psychosis: systematic review
    • Semple DM, McIntosh AM, Lawrie SM. Cannabis as a risk factor for psychosis: systematic review. J Psychopharmacol 2005;19:187-94.
    • (2005) J Psychopharmacol , vol.19 , pp. 187-194
    • Semple, D.M.1    McIntosh, A.M.2    Lawrie, S.M.3
  • 94
    • 0035961131 scopus 로고    scopus 로고
    • Studies on [3H]CP-55940 binding in the human central nervous system: regional specific changes in density of cannabinoid-1 receptors associated with schizophrenia and cannabis use
    • Dean B, Sundram S, Bradbury R, Scarr E, Copolov D. Studies on [3H]CP-55940 binding in the human central nervous system: regional specific changes in density of cannabinoid-1 receptors associated with schizophrenia and cannabis use. Neuroscience 2001;103:9-15.
    • (2001) Neuroscience , vol.103 , pp. 9-15
    • Dean, B.1    Sundram, S.2    Bradbury, R.3    Scarr, E.4    Copolov, D.5
  • 97
    • 0027533003 scopus 로고
    • Effects of chronic marijuana use on human cognition
    • Block RI, Ghoneim MM. Effects of chronic marijuana use on human cognition. Psychopharmacology (Berl) 1993; 110:219-28.
    • (1993) Psychopharmacology (Berl) , vol.110 , pp. 219-228
    • Block, R.I.1    Ghoneim, M.M.2
  • 98
    • 0035138027 scopus 로고    scopus 로고
    • Pharmacology and effects of cannabis: a brief review
    • Ashton CH. Pharmacology and effects of cannabis: a brief review. Br J Psychiatry 2001;178:101-6.
    • (2001) Br J Psychiatry , vol.178 , pp. 101-106
    • Ashton, C.H.1
  • 99
    • 0031945563 scopus 로고    scopus 로고
    • Evaluation of the accuracy of on-site multi-analyte drug testing devices in the determination of the prevalence of illicit drugs in drivers
    • Buchan BJ, Walsh JM, Leaverton PE. Evaluation of the accuracy of on-site multi-analyte drug testing devices in the determination of the prevalence of illicit drugs in drivers. J Forensic Sci 1998;43:395-9.
    • (1998) J Forensic Sci , vol.43 , pp. 395-399
    • Buchan, B.J.1    Walsh, J.M.2    Leaverton, P.E.3
  • 100
    • 26844566936 scopus 로고    scopus 로고
    • Toxicity and carcinogenicity of delta 9-tetrahydrocannabinol in Fischer rats and B6C3F1 mice
    • Chan PC, Sills RC, Braun AG, Haseman JK, Bucher JR. Toxicity and carcinogenicity of delta 9-tetrahydrocannabinol in Fischer rats and B6C3F1 mice. Fundam Appl Toxicol 1996;30:109-17.
    • (1996) Fundam Appl Toxicol , vol.30 , pp. 109-117
    • Chan, P.C.1    Sills, R.C.2    Braun, A.G.3    Haseman, J.K.4    Bucher, J.R.5


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