-
1
-
-
13944276825
-
Twenty years of the AD amyloid hypothesis: A genetic perspective
-
Tanzi RE, Bertram L (2005) Twenty years of the AD amyloid hypothesis: a genetic perspective. Cell 120, 545-555.
-
(2005)
Cell
, vol.120
, pp. 545-555
-
-
Tanzi, R.E.1
Bertram, L.2
-
2
-
-
0021256895
-
AD: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein
-
Glenner GG,WongCW(1984) AD: initial report of the purification and characterization of a novel cerebrovascular amyloid protein. Biochem Biophys Res Commun 120, 885-890.
-
(1984)
Biochem Biophys Res Commun
, vol.120
, pp. 885-890
-
-
Glenner, G.G.1
Wong, C.W.2
-
3
-
-
0022744803
-
Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology
-
Grundke-Iqbal I, Iqbal K, Tung YC, Quinlan M, Wisniewski HM, Binder LI (1986) Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology. Proc Natl Acad Sci U S A 83, 4913-4917.
-
(1986)
Proc Natl Acad Sci U S A
, vol.83
, pp. 4913-4917
-
-
Grundke-Iqbal, I.1
Iqbal, K.2
Tung, Y.C.3
Quinlan, M.4
Wisniewski, H.M.5
Binder, L.I.6
-
4
-
-
0037041420
-
Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases
-
Bucciantini M, Giannoni E, Chiti F, Baroni F, Formigli L, Zurdo J, Taddei N, Ramponi G, Dobson CM, Stefani M(2002) Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases. Nature 416, 507-511.
-
(2002)
Nature
, vol.416
, pp. 507-511
-
-
Bucciantini, M.1
Giannoni, E.2
Chiti, F.3
Baroni, F.4
Formigli, L.5
Zurdo, J.6
Taddei, N.7
Ramponi, G.8
Dobson, C.M.9
Stefani, M.10
-
5
-
-
20244365677
-
Neurophysiological predictors of long term response to AChE inhibitors in AD patients
-
Di Lazzaro V, Oliviero A, Pilato F, Saturno E, Dileone M, Marra C, Ghirlanda S, Ranieri F, Gainotti G, Tonali P (2005) Neurophysiological predictors of long term response to AChE inhibitors in AD patients. J Neurol Neurosurg Psychiatry 76, 1064-1069.
-
(2005)
J Neurol Neurosurg Psychiatry
, vol.76
, pp. 1064-1069
-
-
Di Lazzaro, V.1
Oliviero, A.2
Pilato, F.3
Saturno, E.4
Dileone, M.5
Marra, C.6
Ghirlanda, S.7
Ranieri, F.8
Gainotti, G.9
Tonali, P.10
-
6
-
-
0037162725
-
Newtherapies. NewAlzheimer's treatments that may ease the mind
-
Helmuth L (2002) Newtherapies. NewAlzheimer's treatments that may ease the mind. Science 297, 1260-1262.
-
(2002)
Science
, vol.297
, pp. 1260-1262
-
-
Helmuth, L.1
-
7
-
-
0034682788
-
Inhibition of toxicity in the β-amyloid peptide fragment β-(25-35) using N-methylated derivatives. A general strategy to prevent amyloid formation
-
DOI 10.1074/jbc.M003554200
-
Hughes E, Burke RM, Doig AJ (2000) Inhibition of toxicity in the beta-amyloid peptide fragment beta-(25-35) using Nmethylated derivatives: a general strategy to prevent amyloid formation. J Biol Chem 275, 25109-25115. (Pubitemid 30687002)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.33
, pp. 25109-25115
-
-
Hughes, E.1
Burke, R.M.2
Doig, A.J.3
-
8
-
-
4444276735
-
Clearance of Alzheimer's A-beta peptide: The many roads to perdition
-
Tanzi RE, Moir RD, Wagner SL (2004) Clearance of Alzheimer's A-beta peptide: the many roads to perdition. Neuron 43, 605-608.
-
(2004)
Neuron
, vol.43
, pp. 605-608
-
-
Tanzi, R.E.1
Moir, R.D.2
Wagner, S.L.3
-
9
-
-
0034711656
-
Estrogen for AD in women: Randomized, doubleblind, placebo-controlled trial
-
Henderson VW, Paganini-Hill A, Miller BL, Elble RJ, Reyes PF, Shoupe D, McCleary CA, Klein RA, Hake AM, Farlow MR (2000) Estrogen for AD in women: randomized, doubleblind, placebo-controlled trial. Neurology 54, 295-301.
-
(2000)
Neurology
, vol.54
, pp. 295-301
-
-
Henderson, V.W.1
Paganini-Hill, A.2
Miller, B.L.3
Elble, R.J.4
Reyes, P.F.5
Shoupe, D.6
McCleary, C.A.7
Klein, R.A.8
Hake, A.M.9
Farlow, M.R.10
-
11
-
-
15044364801
-
Estradiol protects cultured articular chondrocytes from oxygen-radical-induced damage
-
Claassen H, Schunke M, Kurz B (2005) Estradiol protects cultured articular chondrocytes from oxygen-radical-induced damage. Cell Tissue Res 319, 439-445.
-
(2005)
Cell Tissue Res
, vol.319
, pp. 439-445
-
-
Claassen, H.1
Schunke, M.2
Kurz, B.3
-
12
-
-
34147181810
-
Flavonoids possess neuroprotective effects on cultured pheochromocytoma PC12 cells: A comparison of different flavonoids in activating estrogenic effect and in preventing beta-amyloid-induced cell death
-
Zhu JT, Choi RCY, Chu GKY, Cheung AWH, Gao QT, Li J, Jiang ZY, Dong TTX, Tsim KWK (2007) Flavonoids possess neuroprotective effects on cultured pheochromocytoma PC12 cells: a comparison of different flavonoids in activating estrogenic effect and in preventing beta-amyloid-induced cell death. J Agric Food Chem 55, 2438-2445.
-
(2007)
J Agric Food Chem
, vol.55
, pp. 2438-2445
-
-
Zhu, J.T.1
Choi, R.C.Y.2
Chu, G.K.Y.3
Cheung, A.W.H.4
Gao, Q.T.5
Li, J.6
Jiang, Z.Y.7
Dong, T.T.X.8
Tsim, K.W.K.9
-
13
-
-
0035895957
-
The neuroprotective effects of phytoestrogens on amyloid beta protein-induced toxicity are mediated by abrogating the activation of caspase cascade in rat cortical neurons
-
Wang CN, Chi CW, Lin YL, Chen CF, Shiao YJ (2001) The neuroprotective effects of phytoestrogens on amyloid beta protein-induced toxicity are mediated by abrogating the activation of caspase cascade in rat cortical neurons. J Biol Chem 276, 5287-5295.
-
(2001)
J Biol Chem
, vol.276
, pp. 5287-5295
-
-
Wang, C.N.1
Chi, C.W.2
Lin, Y.L.3
Chen, C.F.4
Shiao, Y.J.5
-
14
-
-
0042303937
-
Chemical assessment of roots of Panax notoginseng in China: Regional and seasonal variations in its active constituents
-
Dong TTX, Cui XM, Song ZH, Zhao KJ, Ji ZN, Lo CK, Tsim KWK (2003) Chemical assessment of roots of Panax notoginseng in China: regional and seasonal variations in its active constituents. J Agric Food Chem 51, 4617-4623.
-
(2003)
J Agric Food Chem
, vol.51
, pp. 4617-4623
-
-
Dong, T.T.X.1
Cui, X.M.2
Song, Z.H.3
Zhao, K.J.4
Ji, Z.N.5
Lo, C.K.6
Tsim, K.W.K.7
-
15
-
-
0028868824
-
Serum-free B27/neurobasal medium supports differentiated growth of neurons from the striatum, substantia nigra, septum, cerebral cortex, cerebellum, and dentate gyrus
-
Brewer GJ (1995) Serum-free B27/neurobasal medium supports differentiated growth of neurons from the striatum, substantia nigra, septum, cerebral cortex, cerebellum, and dentate gyrus. J Neurosci Res 42, 674-683.
-
(1995)
J Neurosci Res
, vol.42
, pp. 674-683
-
-
Brewer, G.J.1
-
16
-
-
20044370990
-
Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo.
-
Yang F, Lim GP, Begum AN, Ubeda OJ, Simmons MR, Ambegaokar SS, Chen PP, Kayed R, Glabe CG, Frautschy SA, Cole GM (2005) Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo. J Biol Chem 280, 5892-5901.
-
(2005)
J Biol Chem
, vol.280
, pp. 5892-5901
-
-
Yang, F.1
Lim, G.P.2
Begum, A.N.3
Ubeda, O.J.4
Simmons, M.R.5
Ambegaokar, S.S.6
Chen, P.P.7
Kayed, R.8
Glabe, C.G.9
Frautschy, S.A.10
Cole, G.M.11
-
17
-
-
0020686674
-
AD: A disorder of cortical cholinergic innervation
-
Coyle JT, Price DL, DeLong MR (1983) AD: a disorder of cortical cholinergic innervation. Science 219, 1184-1190.
-
(1983)
Science
, vol.219
, pp. 1184-1190
-
-
Coyle, J.T.1
Price, D.L.2
Delong, M.R.3
-
18
-
-
33846313605
-
Pharmacological profile of PMS777, a newAChE inhibitor with PAF antagonistic activity
-
Li J, Huang H, Miezan Ezoulin JM, Gao XL, Massicot F, Dong CZ, Heymans F, Chen HZ (2007) Pharmacological profile of PMS777, a newAChE inhibitor with PAF antagonistic activity. Int J Neuropsychopharmacol 10, 21-29.
-
(2007)
Int J Neuropsychopharmacol
, vol.10
, pp. 21-29
-
-
Li, J.1
Huang, H.2
Miezan Ezoulin, J.M.3
Gao, X.L.4
Massicot, F.5
Dong, C.Z.6
Heymans, F.7
Chen, H.Z.8
-
19
-
-
63649089666
-
Side effects of approved antidementives
-
Mimica N, Presecki P (2009) Side effects of approved antidementives. Psychiatr Danub 21, 108-113.
-
(2009)
Psychiatr Danub
, vol.21
, pp. 108-113
-
-
Mimica, N.1
Presecki, P.2
-
20
-
-
0034923423
-
A review of the evidence for the use of phytoestrogens as a replacement for traditional estrogen replacement therapy
-
Glazier MG, Bowman MA (2001) A review of the evidence for the use of phytoestrogens as a replacement for traditional estrogen replacement therapy. Arch Intern Med 161, 1161-1172.
-
(2001)
Arch Intern Med
, vol.161
, pp. 1161-1172
-
-
Glazier, M.G.1
Bowman, M.A.2
-
21
-
-
0033227489
-
Growth inhibition of human breast cancer cells by herbs and phytoestrogens
-
Dixon-Shanies D, Shaikh N (1999) Growth inhibition of human breast cancer cells by herbs and phytoestrogens. Oncol Rep 6, 1383-1387.
-
(1999)
Oncol Rep
, vol.6
, pp. 1383-1387
-
-
Dixon-Shanies, D.1
Shaikh, N.2
-
22
-
-
0035360280
-
Uterine adenocarcinoma in mice treated neonatally with genistein
-
Newbold RR, Banks EP, Bullock B, JeffersonWN(2001) Uterine adenocarcinoma in mice treated neonatally with genistein. Cancer Res 61, 4325-4328.
-
(2001)
Cancer Res
, vol.61
, pp. 4325-4328
-
-
Newbold, R.R.1
Banks, E.P.2
Bullock, B.3
Jefferson, W.N.4
-
23
-
-
0035394121
-
Soy diets containing varying amounts of genistein stimulate growth of estrogen-dependent (MCF-7) tumors in a dosedependent manner
-
Allred CD, Allred KF, Ju YH, Virant SM, Helferich WG (2001) Soy diets containing varying amounts of genistein stimulate growth of estrogen-dependent (MCF-7) tumors in a dosedependent manner. Cancer Res 61, 5045-5050.
-
(2001)
Cancer Res
, vol.61
, pp. 5045-5050
-
-
Allred, C.D.1
Allred, K.F.2
Ju, Y.H.3
Virant, S.M.4
Helferich, W.G.5
-
24
-
-
4444292340
-
Soy processing influences growth of estrogen-dependent breast cancer tumors
-
Allred CD, Allred KF, Ju YH, Goeppinger TS, Doerge DR, Helferich WG (2004) Soy processing influences growth of estrogen-dependent breast cancer tumors. Carcinogenesis 25, 1649-1657.
-
(2004)
Carcinogenesis
, vol.25
, pp. 1649-1657
-
-
Allred, C.D.1
Allred, K.F.2
Ju, Y.H.3
Goeppinger, T.S.4
Doerge, D.R.5
Helferich, W.G.6
-
25
-
-
0037328536
-
Panax notoginseng (Burk.) effects on fibrinogen and lipid plasma level in rats fed on a high-fat diet
-
Cicero AF, Vitale G, Savino G, Arlett R (2003) Panax notoginseng (Burk.) effects on fibrinogen and lipid plasma level in rats fed on a high-fat diet. Phytother Res 17, 174-178.
-
(2003)
Phytother Res
, vol.17
, pp. 174-178
-
-
Cicero, A.F.1
Vitale, G.2
Savino, G.3
Arlett, R.4
-
27
-
-
0013643698
-
Chemical studies of San-Chi Panax notoginseng I: Studies on the constituents of San-Chi root hairs
-
Wei JX,Wang JF, Chang LY, Du YC (1980) Chemical studies of San-Chi Panax notoginseng I: Studies on the constituents of San-Chi root hairs. Acta Pharm Sin 15, 359-364.
-
(1980)
Acta Pharm Sin
, vol.15
, pp. 359-364
-
-
Wei, J.X.1
Wang, J.F.2
Chang, L.Y.3
Du, Y.C.4
-
28
-
-
3042778521
-
Effect of Radix Notoginseng saponins on platelet activating molecule expression and aggregation in patients with blood hyperviscosity syndrome
-
Wang J, Xu J, Zhong JB (2004) Effect of Radix Notoginseng saponins on platelet activating molecule expression and aggregation in patients with blood hyperviscosity syndrome. Zhongguo Zhong Xi Yi Jie He Za Zhi 24, 312-316.
-
(2004)
Zhongguo Zhong Xi Yi Jie He Za Zhi
, vol.24
, pp. 312-316
-
-
Wang, J.1
Xu, J.2
Zhong, J.B.3
-
29
-
-
0020848503
-
Hemodynamic effects of San Chi (Panax notoginseng) root, leaf, flower and saponins on anesthetized dogs
-
Chen ZH,Wang DC, Li HL,Wei JX,Wang JF, Du YC (1983) Hemodynamic effects of San Chi (Panax notoginseng) root, leaf, flower and saponins on anesthetized dogs. Acta Pharm Sin 18, 818-822.
-
(1983)
Acta Pharm Sin
, vol.18
, pp. 818-822
-
-
Chen Zhwang, D.C.1
Li Hlwei Jxwang, J.F.2
Du, Y.C.3
-
30
-
-
0001055123
-
Identification of 3-O-[2-O-(β-D-Xylopyranosyl)-β-D- Galactopyranosyl] flavonoids in horseradish leaves acting as feeding stimulants for a flea beetle
-
Larsen LM, Nielsen JK, Sorensen H (1982) Identification of 3-O-[2-O-(β-D-Xylopyranosyl)-β-D-Galactopyranosyl] flavonoids in horseradish leaves acting as feeding stimulants for a flea beetle. Phytochemistry 21, 1029-1033.
-
(1982)
Phytochemistry
, vol.21
, pp. 1029-1033
-
-
Larsen, L.M.1
Nielsen, J.K.2
Sorensen, H.3
-
31
-
-
0033897394
-
Flavonol glycosides from Epimedium sagittatum and their neurite outgrowth activity on PC12h cells
-
Kuroda M, Mimaki Y, Sashida Y, Umegaki E, Yamazaki M, Chiba K, Mohri T, Kitahara M, Yasuda A, Naoi N, Xu ZW, Li MR (2000) Flavonol glycosides from Epimedium sagittatum and their neurite outgrowth activity on PC12h cells. Planta Med 66, 575-577.
-
(2000)
Planta Med
, vol.66
, pp. 575-577
-
-
Kuroda, M.1
Mimaki, Y.2
Sashida, Y.3
Umegaki, E.4
Yamazaki, M.5
Chiba, K.6
Mohri, T.7
Kitahara, M.8
Yasuda, A.9
Naoi, N.10
Xu, Z.W.11
Li, M.R.12
-
32
-
-
33947319498
-
Neuroprotective effects of icaritin against beta amyloid-induced neurotoxicity in primary cultured rat neuronal cells via estrogendependent pathway
-
Wang Z, Zhang X, Wang H, Qi L, Lou Y (2007) Neuroprotective effects of icaritin against beta amyloid-induced neurotoxicity in primary cultured rat neuronal cells via estrogendependent pathway. Neuroscience 145, 911-922.
-
(2007)
Neuroscience
, vol.145
, pp. 911-922
-
-
Wang, Z.1
Zhang, X.2
Wang, H.3
Qi, L.4
Lou, Y.5
-
33
-
-
0035919828
-
Baicalein protects cortical neurons from beta-amyloid (25-35) induced toxicity
-
Lebeau A, Esclaire F, Rostene W, Pelaprat D (2001) Baicalein protects cortical neurons from beta-amyloid (25-35) induced toxicity. Neuroreport 12, 2199-2202.
-
(2001)
Neuroreport
, vol.12
, pp. 2199-2202
-
-
Lebeau, A.1
Esclaire, F.2
Rostene, W.3
Pelaprat, D.4
-
34
-
-
1642424296
-
Protection against hydrogen peroxideinduced cytotoxicity in PC12 cells by scutellarin
-
Hong H, LiuGQ(2004) Protection against hydrogen peroxideinduced cytotoxicity in PC12 cells by scutellarin. Life Sci 74, 2959-2973.
-
(2004)
Life Sci
, vol.74
, pp. 2959-2973
-
-
Hong, H.1
Liu, G.Q.2
-
35
-
-
73349094325
-
Estrogenic and neuroprotective properties of scutellarin from Erigeron breviscapus: A drug against postmenopausal symptoms and Alzheimer's disease
-
Zhu JT, Choi RC, Li J, Xie HQ, BiCW, Cheung AW, Dong TT, Jiang ZY, Chen JJ, Tsim KWK (2009) Estrogenic and neuroprotective properties of scutellarin from Erigeron breviscapus: A drug against postmenopausal symptoms and Alzheimer's disease. Planta Med 75, 1489-1493.
-
(2009)
Planta Med
, vol.75
, pp. 1489-1493
-
-
Zhu, J.T.1
Choi, R.C.2
Li, J.3
Xie, H.Q.4
Bi, C.W.5
Cheung, A.W.6
Dong, T.T.7
Jiang, Z.Y.8
Chen, J.J.9
Tsim, K.W.K.10
-
36
-
-
0037954417
-
Neuroprotective role of learning in dementia: A biological explanation
-
Addae JI, Youssef FF, Stone TW (2003) Neuroprotective role of learning in dementia: a biological explanation. J Alzheimers Dis 5, 91-104.
-
(2003)
J Alzheimers Dis
, vol.5
, pp. 91-104
-
-
Addae, J.I.1
Youssef, F.F.2
Stone, T.W.3
-
37
-
-
37549022563
-
Changes in readthrough acetylcholinesterase expression modulate amyloid-beta pathology
-
Berson A, Knobloch M, Hanan M, Diamant S, Sharoni M, Schuppli D, Geyer BC, Ravid R, Mor TS, Nitsch RM, Soreq H (2008) Changes in readthrough acetylcholinesterase expression modulate amyloid-beta pathology. Brain 131, 109-119.
-
(2008)
Brain
, vol.131
, pp. 109-119
-
-
Berson, A.1
Knobloch, M.2
Hanan, M.3
Diamant, S.4
Sharoni, M.5
Schuppli, D.6
Geyer, B.C.7
Ravid, R.8
Mor, T.S.9
Nitsch, R.M.10
Soreq, H.11
-
38
-
-
7444253369
-
Flavonoids and the brain: Interactions at the blood-brain barrier and their physiological effects on the central nervous system
-
Youdim KA, Shukitt-Hale B, Joseph JA (2004) Flavonoids and the brain: interactions at the blood-brain barrier and their physiological effects on the central nervous system. Free Radic Biol Med 37, 1683-1693.
-
(2004)
Free Radic Biol Med
, vol.37
, pp. 1683-1693
-
-
Youdim, K.A.1
Shukitt-Hale, B.2
Joseph, J.A.3
-
40
-
-
63649135792
-
Estradiol rescues neurons from global ischemia-induced cell death: Multiple cellular pathways of neuroprotection
-
Lebesgue D, Chevaleyre V, Zukin RS, EtgenAM(2009) Estradiol rescues neurons from global ischemia-induced cell death: multiple cellular pathways of neuroprotection. Steroids 74, 555-561.
-
(2009)
Steroids
, vol.74
, pp. 555-561
-
-
Lebesgue, D.1
Chevaleyre, V.2
Zukin, R.S.3
Etgen, A.M.4
-
41
-
-
33847019273
-
Redox regulation of cellular stress response in neurodegenerative disorders
-
Calabrese V, Guagliano E, Sapienza M, Mancuso C, Butterfield DA, Stella AM(2006) Redox regulation of cellular stress response in neurodegenerative disorders. J Biochem 55, 263-282.
-
(2006)
J Biochem
, vol.55
, pp. 263-282
-
-
Calabrese, V.1
Guagliano, E.2
Sapienza, M.3
Mancuso, C.4
Butterfield, D.A.5
Stella, A.M.6
-
42
-
-
20444488688
-
From clinical evidence to molecular mechanisms underlying neuroprotection afforded by estrogens
-
Amantea D, Russo R, Bagetta G, Corasaniti MT (2005) From clinical evidence to molecular mechanisms underlying neuroprotection afforded by estrogens. Pharmacol Res 52, 119-132.
-
(2005)
Pharmacol Res
, vol.52
, pp. 119-132
-
-
Amantea, D.1
Russo, R.2
Bagetta, G.3
Corasaniti, M.T.4
|