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Volumn 123, Issue 5, 2010, Pages 736-746

Microtubule assembly by the Apc protein is regulated by importin-β-RanGTP

Author keywords

Adenomatous polyposis coli; Importin ; Microtubules; Mitotic spindle

Indexed keywords

APC PROTEIN; ARMADILLO DOMAIN PROTEIN; BETA CATENIN; KARYOPHERIN BETA; RAN PROTEIN;

EID: 77149136080     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.060806     Document Type: Article
Times cited : (26)

References (39)
  • 1
    • 0034611602 scopus 로고    scopus 로고
    • Regulation and function of the interaction between the APC tumour suppressor protein and EB1
    • Askham, J. M., Moncur, P., Markham, A. F. and Morrison, E. E. (2000). Regulation and function of the interaction between the APC tumour suppressor protein and EB1. Oncogene 19, 1950-1958.
    • (2000) Oncogene , vol.19 , pp. 1950-1958
    • Askham, J.M.1    Moncur, P.2    Markham, A.F.3    Morrison, E.E.4
  • 2
    • 0026419320 scopus 로고
    • Catalysis of guanine nucleotide exchange on Ran by the mitotic regulator RCC1
    • Bischoff, F. R. and Ponstingl, H. (1991). Catalysis of guanine nucleotide exchange on Ran by the mitotic regulator RCC1. Nature 354, 80-82.
    • (1991) Nature , vol.354 , pp. 80-82
    • Bischoff, F.R.1    Ponstingl, H.2
  • 4
    • 0028937195 scopus 로고
    • Coactivation of RanGTPase and inhibition of GTP dissociation by Ran-GTP binding protein RanBP1
    • Bischoff, F. R., Krebber, H., Smirnova, E., Dong, W. and Ponstingl, H. (1995). Coactivation of RanGTPase and inhibition of GTP dissociation by Ran-GTP binding protein RanBP1. EMBO J. 14, 705-715.
    • (1995) EMBO J , vol.14 , pp. 705-715
    • Bischoff, F.R.1    Krebber, H.2    Smirnova, E.3    Dong, W.4    Ponstingl, H.5
  • 5
    • 44349165873 scopus 로고    scopus 로고
    • Spatial and temporal coordination of mitosis by Ran GTPase
    • Clarke, P. R. and Zhang, C. (2008). Spatial and temporal coordination of mitosis by Ran GTPase. Nat. Rev. Mol. Cell. Biol. 9, 464-477.
    • (2008) Nat. Rev. Mol. Cell. Biol , vol.9 , pp. 464-477
    • Clarke, P.R.1    Zhang, C.2
  • 6
    • 0032079458 scopus 로고    scopus 로고
    • A domain within the tumor suppressor protein APC shows very similar biochemical properties as the microtubule-associated protein tau
    • Deka, J., Kuhlmann, J. and Muller, O. (1998). A domain within the tumor suppressor protein APC shows very similar biochemical properties as the microtubule-associated protein tau. Eur. J. Biochem. 253, 591-597.
    • (1998) Eur. J. Biochem , vol.253 , pp. 591-597
    • Deka, J.1    Kuhlmann, J.2    Muller, O.3
  • 7
    • 0032608492 scopus 로고    scopus 로고
    • The use of Xenopus egg extracts to study mitotic spindle assembly and function in vitro
    • Desai, A., Murray, A., Mitchison, T. J. and Walczak, C. E. (1999). The use of Xenopus egg extracts to study mitotic spindle assembly and function in vitro. Methods Cell Biol. 61, 385-412.
    • (1999) Methods Cell Biol , vol.61 , pp. 385-412
    • Desai, A.1    Murray, A.2    Mitchison, T.J.3    Walczak, C.E.4
  • 8
    • 2542452815 scopus 로고    scopus 로고
    • The adenomatous polyposis coli protein is required for the formation of robust spindles formed in CSF Xenopus extracts
    • Dikovskaya, D., Newton, I. P. and Nathke, I. S. (2004). The adenomatous polyposis coli protein is required for the formation of robust spindles formed in CSF Xenopus extracts. Mol. Biol. Cell 15, 2978-2991.
    • (2004) Mol. Biol. Cell , vol.15 , pp. 2978-2991
    • Dikovskaya, D.1    Newton, I.P.2    Nathke, I.S.3
  • 10
    • 33745542004 scopus 로고    scopus 로고
    • Misorientation and reduced stretching of aligned sister kinetochores promote chromosome missegregation in EB1- or APC-depleted cells
    • Draviam, V. M., Shapiro, I., Aldridge, B. and Sorger, P. K. (2006). Misorientation and reduced stretching of aligned sister kinetochores promote chromosome missegregation in EB1- or APC-depleted cells. EMBO J. 25, 2814-2827.
    • (2006) EMBO J , vol.25 , pp. 2814-2827
    • Draviam, V.M.1    Shapiro, I.2    Aldridge, B.3    Sorger, P.K.4
  • 11
    • 0346099347 scopus 로고    scopus 로고
    • Importin alpha/beta and Ran-GTP regulate XCTK2 microtubule binding through a bipartite nuclear localization signal
    • Ems-McClung, S. C., Zheng, Y. and Walczak, C. E. (2004). Importin alpha/beta and Ran-GTP regulate XCTK2 microtubule binding through a bipartite nuclear localization signal. Mol. Biol. Cell 15, 46-57.
    • (2004) Mol. Biol. Cell , vol.15 , pp. 46-57
    • Ems-McClung, S.C.1    Zheng, Y.2    Walczak, C.E.3
  • 14
    • 0029853631 scopus 로고    scopus 로고
    • Identification of different roles for RanGDP and RanGTP in nuclear protein import
    • Gorlich, D., Pante, N., Kutay, U., Aebi, U. and Bischoff, F. R. (1996). Identification of different roles for RanGDP and RanGTP in nuclear protein import. EMBO J. 15, 5584-5594.
    • (1996) EMBO J , vol.15 , pp. 5584-5594
    • Gorlich, D.1    Pante, N.2    Kutay, U.3    Aebi, U.4    Bischoff, F.R.5
  • 15
    • 0346849717 scopus 로고    scopus 로고
    • Chromosome instability in colorectal tumor cells is associated with defects in microtubule plus-end attachments caused by a dominant mutation in APC
    • Green, R. A. and Kaplan, K. B. (2003). Chromosome instability in colorectal tumor cells is associated with defects in microtubule plus-end attachments caused by a dominant mutation in APC. J. Cell Biol. 163, 949-961.
    • (2003) J. Cell Biol , vol.163 , pp. 949-961
    • Green, R.A.1    Kaplan, K.B.2
  • 16
    • 0036558281 scopus 로고    scopus 로고
    • Direct binding of NuMA to tubulin is mediated by a novel sequence motif in the tail domain that bundles and stabilizes microtubules
    • Haren, L. and Merdes, A. (2002). Direct binding of NuMA to tubulin is mediated by a novel sequence motif in the tail domain that bundles and stabilizes microtubules. J. Cell Sci. 115, 1815-1824.
    • (2002) J. Cell Sci , vol.115 , pp. 1815-1824
    • Haren, L.1    Merdes, A.2
  • 18
    • 0035853847 scopus 로고    scopus 로고
    • The cadherin cytoplasmic domain is unstructured in the absence of beta-catenin. A possible mechanism for regulating cadherin turnover
    • Huber, A. H., Stewart, D. B., Laurents, D. V., Nelson, W. J. and Weis, W. I. (2001). The cadherin cytoplasmic domain is unstructured in the absence of beta-catenin. A possible mechanism for regulating cadherin turnover. J. Biol. Chem. 276, 12301-12309.
    • (2001) J. Biol. Chem , vol.276 , pp. 12301-12309
    • Huber, A.H.1    Stewart, D.B.2    Laurents, D.V.3    Nelson, W.J.4    Weis, W.I.5
  • 19
    • 0031771883 scopus 로고    scopus 로고
    • The role of the ran GTPase in nuclear assembly and DNA replication: Characterisation of the effects of Ran mutants
    • Hughes, M., Zhang, C., Avis, J. M., Hutchison, C. J. and Clarke, P. R. (1998). The role of the ran GTPase in nuclear assembly and DNA replication: characterisation of the effects of Ran mutants. J. Cell Sci. 111, 3017-3026.
    • (1998) J. Cell Sci , vol.111 , pp. 3017-3026
    • Hughes, M.1    Zhang, C.2    Avis, J.M.3    Hutchison, C.J.4    Clarke, P.R.5
  • 21
    • 0040251482 scopus 로고    scopus 로고
    • Importin beta, transportin, RanBP5 and RanBP7 mediate nuclear import of ribosomal proteins in mammalian cells
    • Jakel, S. and Gorlich, D. (1998). Importin beta, transportin, RanBP5 and RanBP7 mediate nuclear import of ribosomal proteins in mammalian cells. EMBO J. 17, 4491-4502.
    • (1998) EMBO J , vol.17 , pp. 4491-4502
    • Jakel, S.1    Gorlich, D.2
  • 22
    • 0036469888 scopus 로고    scopus 로고
    • Importins fulfil a dual function as nuclear import receptors and cytoplasmic chaperones for exposed basic domains
    • Jakel, S., Mingot, J. M., Schwarzmaier, P., Hartmann, E. and Gorlich, D. (2002). Importins fulfil a dual function as nuclear import receptors and cytoplasmic chaperones for exposed basic domains. EMBO J. 21, 377-386.
    • (2002) EMBO J , vol.21 , pp. 377-386
    • Jakel, S.1    Mingot, J.M.2    Schwarzmaier, P.3    Hartmann, E.4    Gorlich, D.5
  • 23
  • 24
    • 46249113438 scopus 로고    scopus 로고
    • The RanGTP gradient-a GPS for the mitotic spindle
    • Kalab, P. and Heald, R. (2008). The RanGTP gradient-a GPS for the mitotic spindle. J. Cell Sci. 121, 1577-1586.
    • (2008) J. Cell Sci , vol.121 , pp. 1577-1586
    • Kalab, P.1    Heald, R.2
  • 26
    • 46749094255 scopus 로고    scopus 로고
    • Novel self-association of the APC molecule affects APC clusters and cell migration
    • Li, Z., Kroboth, K., Newton, I. P. and Nathke, I. S. (2008). Novel self-association of the APC molecule affects APC clusters and cell migration. J. Cell Sci. 121, 1916-1925.
    • (2008) J. Cell Sci , vol.121 , pp. 1916-1925
    • Li, Z.1    Kroboth, K.2    Newton, I.P.3    Nathke, I.S.4
  • 27
    • 41549117418 scopus 로고    scopus 로고
    • Cell regulation by the Apc protein Apc as master regulator of epithelia
    • McCartney, B. M. and Nathke, I. S. (2008). Cell regulation by the Apc protein Apc as master regulator of epithelia. Curr. Opin. Cell Biol. 20, 186-193.
    • (2008) Curr. Opin. Cell Biol , vol.20 , pp. 186-193
    • McCartney, B.M.1    Nathke, I.S.2
  • 28
    • 0027930066 scopus 로고
    • The APC gene product associates with microtubules in vivo and promotes their assembly in vitro
    • Munemitsu, S., Souza, B., Muller, O., Albert, I., Rubinfeld, B. and Polakis, P. (1994). The APC gene product associates with microtubules in vivo and promotes their assembly in vitro. Cancer Res. 54, 3676-3681.
    • (1994) Cancer Res , vol.54 , pp. 3676-3681
    • Munemitsu, S.1    Souza, B.2    Muller, O.3    Albert, I.4    Rubinfeld, B.5    Polakis, P.6
  • 29
    • 0035838422 scopus 로고    scopus 로고
    • Critical role for the EB1 and APC interaction in the regulation of microtubule polymerization
    • Nakamura, M., Zhou, X. Z. and Lu, K. P. (2001). Critical role for the EB1 and APC interaction in the regulation of microtubule polymerization. Curr. Biol. 11, 1062-1067.
    • (2001) Curr. Biol , vol.11 , pp. 1062-1067
    • Nakamura, M.1    Zhou, X.Z.2    Lu, K.P.3
  • 30
    • 0029982877 scopus 로고    scopus 로고
    • The adenomatous polyposis coli tumor suppressor protein localizes to plasma membrane sites involved in active cell migration
    • Nathke, I. S., Adams, C. L., Polakis, P., Sellin, J. H. and Nelson, W. J. (1996). The adenomatous polyposis coli tumor suppressor protein localizes to plasma membrane sites involved in active cell migration. J. Cell Biol. 134, 165-179.
    • (1996) J. Cell Biol , vol.134 , pp. 165-179
    • Nathke, I.S.1    Adams, C.L.2    Polakis, P.3    Sellin, J.H.4    Nelson, W.J.5
  • 31
    • 33846193290 scopus 로고    scopus 로고
    • The many ways of Wnt in cancer
    • Polakis, P. (2007). The many ways of Wnt in cancer. Curr. Opin. Genet. Dev. 17, 45-51.
    • (2007) Curr. Opin. Genet. Dev , vol.17 , pp. 45-51
    • Polakis, P.1
  • 33
    • 0019306863 scopus 로고
    • Functional implications of cold-stable microtubules in kinetochore fibers of insect spermatocytes during anaphase
    • Salmon, E. D. and Begg, D. A. (1980). Functional implications of cold-stable microtubules in kinetochore fibers of insect spermatocytes during anaphase. J. Cell Biol. 85, 853-865.
    • (1980) J. Cell Biol , vol.85 , pp. 853-865
    • Salmon, E.D.1    Begg, D.A.2
  • 34
    • 46649086170 scopus 로고    scopus 로고
    • RanBP10 is a cytoplasmic guanine nucleotide exchange factor that modulates noncentrosomal microtubules
    • Schulze, H., Dose, M., Korpal, M., Meyer, I., Italiano, J. E., Jr and Shivdasani, R. A. (2008). RanBP10 is a cytoplasmic guanine nucleotide exchange factor that modulates noncentrosomal microtubules. J. Biol. Chem. 283, 14109-14119.
    • (2008) J. Biol. Chem , vol.283 , pp. 14109-14119
    • Schulze, H.1    Dose, M.2    Korpal, M.3    Meyer, I.4    Italiano Jr, J.E.5    Shivdasani, R.A.6
  • 36
    • 0242655666 scopus 로고    scopus 로고
    • Chromosome assembly in vitro using Xenopus egg extracts
    • ed. W. Bickmore, pp, Oxford: Oxford University Press
    • Swedlow, J. R. (1999). Chromosome assembly in vitro using Xenopus egg extracts. In Chromosome Analysis (ed. W. Bickmore), pp. 165-182. Oxford: Oxford University Press.
    • (1999) Chromosome Analysis , pp. 165-182
    • Swedlow, J.R.1
  • 37
    • 13444261036 scopus 로고    scopus 로고
    • Truncating APC mutations have dominant effects on proliferation, spindle checkpoint control, survival and chromosome stability
    • Tighe, A., Johnson, V. L. and Taylor, S. S. (2004). Truncating APC mutations have dominant effects on proliferation, spindle checkpoint control, survival and chromosome stability. J. Cell Sci. 117, 6339-6353.
    • (2004) J. Cell Sci , vol.117 , pp. 6339-6353
    • Tighe, A.1    Johnson, V.L.2    Taylor, S.S.3
  • 39
    • 0035176077 scopus 로고    scopus 로고
    • Binding of the adenomatous polyposis coli protein to microtubules increases microtubule stability and is regulated by GSK3 beta phosphorylation
    • Zumbrunn, J., Kinoshita, K., Hyman, A. A. and Nathke, I. S. (2001). Binding of the adenomatous polyposis coli protein to microtubules increases microtubule stability and is regulated by GSK3 beta phosphorylation. Curr. Biol. 11, 44-49.
    • (2001) Curr. Biol , vol.11 , pp. 44-49
    • Zumbrunn, J.1    Kinoshita, K.2    Hyman, A.A.3    Nathke, I.S.4


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