Antioxidant strategy to rescue synaptosomes from oxidative damage and energy failure in neurotoxic models in rats: Protective role of S-allylcysteine

Journal of Neural Transmission

Volumn 117, Issue 1, 2010, Pages 35-44

  Elinos Calderón, Diana ^a   Robledo Arratia, Yolanda ^a   Pérez De La Cruz, Verónica ^a   Maldonado, Perla D ^a   Galván Arzate, Sonia ^a   Pedraza Chaverrí, José ^b   Santamaría, Abel ^a  

^a NATIONAL INSTITUTE OF NEUROLOGY AND NEUROSURGERY   (Mexico)

^b UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

Energy depletion; Excitotoxicity; Functional recovery; Oxidative damage; S allylcysteine post treatment; Synaptosomes; Synergism

Indexed keywords

3 NITROPROPIONIC ACID; QUINOLINIC ACID; S ALLYLCYSTEINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DRUG MECHANISM; ENERGY METABOLISM; EXCITOTOXICITY; IN VITRO STUDY; IN VIVO STUDY; LIPID PEROXIDATION; MALE; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; SYNAPTOSOME;

ANIMALS; ANTIOXIDANTS; BRAIN; CORPUS STRIATUM; CYSTEINE; DISEASE MODELS, ANIMAL; DYSKINESIA, DRUG-INDUCED; LIPID PEROXIDATION; MALE; MITOCHONDRIA; NEURODEGENERATIVE DISEASES; NEURONS; NEUROPROTECTIVE AGENTS; NITRO COMPOUNDS; OXIDATIVE STRESS; PROPIONIC ACIDS; QUINOLINIC ACID; RATS; RATS, WISTAR; SYNAPTOSOMES; TIME FACTORS;

EID: 76949103417     PISSN: 03009564     EISSN: 14351463     Source Type: Journal    
DOI: 10.1007/s00702-009-0299-5     Document Type: Article

References (52)

1. T Alexi PE Hughes RL Faul CE Williams 1998 3- Nitropropionic acid's lethal triplet: cooperative pathways of neurodegeneration NeuroReport 9 R57 R64 10.1097/00001756-199808030-00001 1:CAS:528:DyaK1cXlvVClsbo%3D 9721909
2. MF Beal 2004 Mitochondrial dysfunction and oxidative damage in Alzheimer's and Parkinson's diseases and coenzyme Q10 as a potential treatment J Bioenerg Biomembr 36 381 386 10.1023/B:JOBB.0000041772.74810.92 1:CAS:528:DC%2BD2cXnsFyjur8%3D 15377876 (Pubitemid 39619845)
3. MF Beal NW Kowall DW Ellison MF Mazurek KJ Swartz JB Martin 1986 Replication of the neurochemical characteristics of Huntington's disease by quinolinic acid Nature 321 168 171 10.1038/321168a0 1:CAS:528:DyaL28XktVCmtrg%3D 2422561
4. WM Behan M McDonald LG Darlington TW Stone 1999 Oxidative stress as a mechanism for quinolinic acid-induced hippocampal damage: protection by melatonin and deprenyl Br J Pharmacol 128 1754 1760 10.1038/sj.bjp.0702940 1:CAS:528:DC%2BD3cXktFKksw%3D%3D 10588931
5. Z Binienda A Virmani B Przybyla-Zawislak L Schmued 2004 Neuroprotective effect of l-carnitine in the 3-nitropropionic acid (3-NPA)-evoked neurotoxicity in rats Neurosci Lett 367 264 267 10.1016/j.neulet.2004.05.031 1:CAS:528:DC%2BD2cXntFWqt7k%3D 15331167 (Pubitemid 39141241)
6. E Brouillet BG Jenkins BT Hyman RJ Ferrante NW Kowall R Srivastava DS Roy BR Rosen MF Beal 1993 Age-dependent vulnerability of the striatum to the mitochondrial toxin 3-nitropropionic acid J Neurochem 60 356 359 10.1111/j.1471-4159.1993.tb05859.x 1:CAS:528:DyaK3sXpsFOqtg%3D%3D 8417157 (Pubitemid 23006739)
7. E Brouillet F Condé MF Beal P Hantraye 1999 Replicating Huntington's disease phenotype in experimental animals Prog Neurobiol 59 427 468 10.1016/S0301-0082(99)00005-2 1:CAS:528:DyaK1MXmsFOhs7c%3D 10515664 (Pubitemid 29392967)
8. Chauhan NB (2006) Effect of aged garlic extract on APP processing and tau phosphorylation in Alzheimer's transgenic model Tg2576. J Ethnopharmacol 108:385-394 (Epub 13 June 2006)
9. JT Coyle P Puttfarcken 1993 Oxidative stress, glutamate, and neurodegenerative disorders Science 262 689 695 10.1126/science.7901908 1:CAS:528:DyaK2cXlvVek 7901908
10. A Dairam R Fogel S Daya JL Limson 2008 Antioxidant and iron-binding properties of curcumin, capsaicin, and S-allylcysteine reduce oxidative stress in rat brain homogenate J Agric Food Chem 56 3350 3356 10.1021/jf0734931 1:CAS:528:DC%2BD1cXkvVKgu7w%3D 18422331 (Pubitemid 351746066)
11. Dinkova-Kostova AT, Talalay P (2008) Direct and indirect antioxidant properties of inducers of cytoprotective proteins. Mol Nutr Food Res 52(Suppl):S128-S138
12. Elinos-Calderón D, Robledo-Arratia Y, Pérez-De La Cruz V, Pedraza-Chaverrí J, Ali SF, Santamaría A (2009) Early nerve ending rescue from oxidative damage and energy failure by l-carnitine as post-treatment in two neurotoxic models in rat: recovery of antioxidant and reductive capacities. Exp Brain Res 197:287-296
13. I Ferrer R Blanco M Carmona 2001 Differential expression of active, phosphorylation-dependent MAP kinases, MAPK/ERK, SAPK/JNK and p38, and specific transcription factor substrates following quinolinic acid excitotoxicity in the rat Mol Brain Res 94 48 58 10.1016/S0169-328X(01)00198-X 1:CAS:528: DC%2BD3MXnsVSnt7w%3D 11597764 (Pubitemid 32964745)
14. E García D Limón V Pérez-De La Cruz M Giordano M Díaz-Muñoz PD Maldonado MN Herrera-Mundo J Pedraza-Chaverrí A Santamaría 2008 Lipid peroxidation, mitochondrial dysfunction and neurochemical and behavioural deficits in different neurotoxic models: Protective role of S-allylcysteine Free Radic Res 42 892 902 10.1080/10715760802506356 18985488
15. Z Geng Y Rong BH Lau 1997 S-Allyl cysteine inhibits activation of nuclear factor kappa B in human T cells Free Radic Biol Med 23 345 350 10.1016/S0891-5849(97)00006-3 1:CAS:528:DyaK2sXktFOls7c%3D 9199898 (Pubitemid 27276616)
16. MN Herrera-Mundo D Silva-Adaya PD Maldonado S Galván-Arzate L Andrés-Martínez V Pérez-De La Cruz J Pedraza- Chaverrí A Santamaría 2006 S-Allylcysteine prevents the rat from 3-nitropropionic acid-induced hyperactivity, early markers of oxidative stress and mitochondrial dysfunction Neurosci Res 56 39 44 10.1016/j.neures.2006.04.018 1:CAS:528:DC%2BD28XptFCis7c%3D 16806549 (Pubitemid 44292883)
17. N Ide BH Lau 1997 Garlic compounds protect vascular endothelial cells from oxidized low density lipoprotein-induced injury J Pharm Pharmacol 49 908 911 1:CAS:528:DyaK2sXmsV2jt74%3D 9306260 (Pubitemid 27424871)
18. N Ide BH Lau 2001 Garlic compounds minimize intracellular oxidative stress and inhibit nuclear factor-kB activation J Nutr 131 1020 1026
19. K Ishige N Takagi T Imai WD Rausch Y Kosuge T Kihara K Kusama-Eguchi H Ikeda AR Cools JL Waddington N Koshikawa Y Ito 2007 Role of caspase-12 in amyloid beta-peptide-induced toxicity in organotypic hippocampal slices cultured for long periods J Pharmacol Sci 104 46 55 10.1254/jphs.FP0061533 1:CAS:528:DC%2BD2sXmt1Wrtro%3D 17452809 (Pubitemid 46790315)
20. KM Kim SB Chun MS Koo WJ Choi TW Kim YG Kwon HT Chung TR Billiar YM Kim 2001 Differential regulation of NO availability from macrophages and endothelial cells by the garlic component S-allyl cysteine Free Radic Biol Med 30 747 756 10.1016/S0891-5849(01)00460-9 1:CAS:528:DC%2BD3MXit1Sjur8%3D 11275474 (Pubitemid 32245580)
21. JM Kim JC Lee N Chang HS Chun WK Kim 2006 S-Allyl-l-cysteine attenuates cerebral ischemic injury by scavenging peroxynitrite and inhibiting the activity of extracellular signal-regulated kinase Free Radic Res 40 827 835 10.1080/10715760600719540 1:CAS:528:DC%2BD28XovFGksLg%3D 17015261 (Pubitemid 44480493)
22. MT Lin MF Beal 2006 Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases Nature 443 787 795 10.1038/nature05292 1:CAS:528:DC%2BD28XhtVyktbbO 17051205 (Pubitemid 44622683)
23. OH Lowry NJ Rosebrough AL Farr RJ Randall 1951 Protein measurement with the Folin phenol reagent J Biol Chem 193 265 275 1:CAS:528:DyaG38XhsVyrsw%3D%3D 14907713
24. AC Ludolph F He PS Spencer J Hammerstad M Sabri 1991 3-Nitropropionic acid-exogenous animal neurotoxin and possible human striatal toxin Can J Neurol Sci 18 492 498 1:STN:280:DyaK387ksFGguw%3D%3D 1782616
25. PD Maldonado D Barrera I Rivero R Mata ON Medina-Campos R Hernández-Pando J Pedraza-Chaverrí 2003 Antioxidant S-allylcysteine prevents gentamicin-induced oxidative stress and renal damage Free Radic Biol Med 35 317 324 10.1016/S0891-5849(03)00312-5 1:CAS:528:DC%2BD3sXls1Omtrg%3D 12885594 (Pubitemid 37288932)
26. RL Martin HG Lloyd AI Cowan 1994 The early events of oxygen and glucose deprivation: setting the scene for neuronal death? Trends Neurosci 17 251 257 10.1016/0166-2236(94)90008-6 1:CAS:528:DyaK2cXltVGhu7Y%3D 7521086 (Pubitemid 24150558)
27. 1 cells of potassium dichromate-induced toxicity Food Chem Toxicol 45 2030 2039 10.1016/j.fct.2007.05.002 1:CAS:528:DC%2BD2sXovFyht7Y%3D 17576034 (Pubitemid 47243644)
28. T Moriguchi H Matsuura Y Kodera Y Itakura H Katsuki H Saito N Nishiyama 1997 Neurotrophic activity of organosulfur compounds having a thioallyl group on cultured rat hippocampal neurons Neurochem Res 22 1449 1452 10.1023/A:1021946210399 1:CAS:528:DyaK2sXntVGhsb0%3D 9357009 (Pubitemid 27461120)
29. DG Nicholls L Johnson-Cadwell S Vesce M Jekabsons N Yadava 2007 Bioenergetics of mitochondria in cultured neurons and their role in glutamate excitotoxicity J Neurosci Res 85 3206 3212 10.1002/jnr.21290 1:CAS:528:DC%2BD1cXjtFCls7k%3D 17455297 (Pubitemid 350058509)
30. Y Numagami ST Ohnishi 2001 S-Allylcysteine inhibits free radical production, lipid peroxidation and neuronal damage in rat brain ischemia J Nutr 131 1100S 1105S 1:CAS:528:DC%2BD3MXhvVOhsrs%3D 11238825
31. Y Numagami S Sato ST Ohnishi 1996 Attenuation of rat ischemic brain damage by aged garlic extracts: a possible protecting mechanism as antioxidants Neurochem Int 29 135 143 10.1016/0197-0186(95)00117-4 1:CAS:528: DyaK28Xks1KhsbY%3D 8837042 (Pubitemid 26232000)
32. Z Pang JW Geddes 1997 Mechanisms of cell death induced by the mitochondrial toxin 3-nitropropionic acid: acute excitotoxic necrosis and delayed apoptosis J Neurosci 17 3064 3073 1:CAS:528:DyaK2sXislaiu70%3D 9096141
33. Paxinos G, Watson C (1998) The rat brain in stereotaxic coordinates. Academic Press, San Diego
34. Q Peng AR Buz'Zard BH Lau 2002 Neuroprotective effect of garlic compounds in amyloid-beta peptide-induced apoptosis in vitro Med Sci Monit 8 BR328 BR337 1:CAS:528:DC%2BD38Xntl2rtLs%3D 12165737
35. V Pérez-De La Cruz C González-Cortés S Galván-Arzate ON Medina-Campos F Pérez-Severiano SF Ali J Pedraza-Chaverrí A Santamaría 2005 Excitotoxic brain damage involves early peroxynitrite formation in a model of Huntington's disease in rats: protective role of iron porphyrinate 5, 10, 15, 20-tetrakis (4-sulfonatophenyl)porphyrinate iron (III) Neuroscience 135 463 474 10.1016/j.neuroscience.2005.06.027 16111817 (Pubitemid 41317384)
36. V Pérez-De La Cruz M Konigsberg J Pedraza-Chaverrí N Herrera-Mundo M Díaz-Muñoz J Morán T Fortoul-van der Goes A Rondán-Zárate PD Maldonado SF Ali A Santamaría 2008 Cytoplasmic calcium mediates oxidative damage in an excitotoxic/energetic deficit synergic model in rats Eur J Neurosci 27 1075 1085 10.1111/j.1460-9568. 2008.06088.x 18364032
37. F Pérez-Severiano M Rodríguez-Pérez J Pedraza-Chaverrí PD Maldonado ON Medina-Campos A Ortíz-Plata A Sánchez-García J Villeda-Hernández S Galván-Arzate P Aguilera A Santamaría 2004 S-Allylcysteine, a garlic-derived antioxidant, ameliorates quinolinic acid-induced neurotoxicity and oxidative damage in rats Neurochem Int 45 1175 1183 10.1016/j.neuint.2004.06.008 15380627 (Pubitemid 39222059)
38. F Pérez-Severiano R Salvatierra-Sánchez M Rodríguez-Pérez EY Cuevas-Martínez J Guevara D Limón PD Maldonado ON Medina-Campos J Pedraza-Chaverrí A Santamaría 2004 S-Allylcysteine prevents amyloid-β peptide-induced oxidative stress in rat hippocampus and ameliorates learning deficits Eur J Pharmacol 489 197 202 10.1016/j.ejphar.2004.03.001 15087243 (Pubitemid 38496229)
39. JI Rossato LA Ketzer FB Centurião SJ Silva DS Lüdtke G Zeni AL Braga MA Rubin JB Rocha 2002 Antioxidant properties of new chalcogenides against lipid peroxidation in rat brain Neurochem Res 27 297 303 10.1023/A:1014907228580 1:CAS:528:DC%2BD3sXjsFGj 11958531 (Pubitemid 34273571)
40. SM Rothman JW Olney 1986 Glutamate and the pathophysiology of hypoxic-ischemic brain damage Ann Neurol 19 105 111 10.1002/ana.410190202 1:CAS:528:DyaL28XhsVKgsbw%3D 2421636
41. A Santamaría ME Jiménez 2005 Oxidative/nitrosative stress, a common factor in different neurotoxic paradigms: an overview Curr Top Neurochem 4 1 20
42. A Santamaría C Ríos 1993 MK-801, an N-methyl-d-aspartate receptor antagonist, blocks quinolinic acid-induced lipid peroxidation in rat corpus striatum Neurosci Lett 159 51 54 10.1016/0304-3940(93)90796-N 8264978
43. K Sas H Robotka J Toldi L Vécsei 2007 Mitochondria, metabolic disturbances, oxidative stress and the kynurenine system, with focus on neurodegenerative disorders J Neurol Sci 257 221 239 10.1016/j.jns.2007.01.033 1:CAS:528:DC%2BD2sXmtlWgurw%3D 17462670 (Pubitemid 46856508)
44. R Schwarcz WO Whetsell Jr RM Mangano 1983 Quinolinic acid: an endogenous metabolite that produces axon-sparing lesions in rat brain Science 219 316 318 10.1126/science.6849138 1:CAS:528:DyaL3sXmvF2gsQ%3D%3D 6849138
45. R Schwarcz AC Foster ED French WO Whetsell Jr C Köhler 1984 Excitotoxic models for neurodegenerative disorders Life Sci 35 19 32 10.1016/0024-3205(84)90148-6 1:CAS:528:DyaL2cXksFalsrg%3D 6234446 (Pubitemid 14122435)
46. G Sener A Sakarcan BC Yegen 2007 Role of garlic in the prevention of ischemia-reperfusion injury Mol Nutr Food Res 51 1345 1352 10.1002/mnfr. 200700078 1:CAS:528:DC%2BD2sXhtlKqsbnO 17966137 (Pubitemid 350195608)
47. D Silva-Adaya V Pérez-De La Cruz MN Herrera-Mundo K Mendoza-Macedo J Villeda-Hernández Z Binienda SF Ali A Santamaría 2008 Excitotoxic damage, disrupted energy metabolism, and oxidative stress in the rat brain: antioxidant and neuroprotective effects of l-carnitine J Neurochem 105 677 689 10.1111/j.1471-4159.2007.05174.x 1:CAS:528:DC%2BD1cXlsl2huro%3D 18194214 (Pubitemid 351562720)
48. AJ Smith RA Smith TW Stone 2009 5-Hydroxyanthranilic acid, a tryptophan metabolite, generates oxidative stress and neuronal death via p38 activation in cultured cerebellar granule neurons Neurotox Res 15 303 310 10.1007/s12640-009- 9034-0 1:CAS:528:DC%2BD1MXhtVejurnO 19384564
49. TW Stone 1993 Neuropharmacology of quinolinic and kynurenic acids Pharmacol Rev 45 309 379 1:CAS:528:DyaK3sXmtFKltr8%3D 8248282
50. I Túnez A Santamaría 2009 Model of Huntington's disease induced with 3-nitropropionic acid Rev Neurol 48 430 434 19340784
51. I Túnez P Montilla M Del Carmen-Muñoz M Feijóo M Salcedo 2004 Protective effect of melatonin on 3-nitropropionic acid-induced oxidative stress in synaptosomes in an animal model of Huntington's disease J Pineal Res 37 252 256 10.1111/j.1600-079X.2004.00163.x 15485551 (Pubitemid 39457046)
52. T Yamasaki L Li BH Lau 1994 Garlic compounds protect vascular endothelial cells from hydrogen peroxide-induced oxidant injury Phytother Res 8 408 412 10.1002/ptr.2650080706 1:CAS:528:DyaK2MXivFajtr8%3D (Pubitemid 24369425)