Early nerve ending rescue from oxidative damage and energy failure by l-carnitine as post-treatment in two neurotoxic models in rat: Recovery of antioxidant and reductive capacities

Experimental Brain Research

Volumn 197, Issue 3, 2009, Pages 287-296

  Elinos Calderón, Diana ^a   Robledo Arratia, Yolanda ^a   Pérez De La Cruz, Verónica ^a   Pedraza Chaverrí, José ^b   Ali, Syed F ^c   Santamaría, Abel ^a,c  

^a NATIONAL INSTITUTE OF NEUROLOGY AND NEUROSURGERY   (Mexico)

^b Universidad Nacional Autonoma de Mexico Facultad de Quimica   (Mexico)

^c NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

Author keywords

Energy depletion; Excitotoxicity; Functional recovery; L carnitine post treatment; Oxidative damage; Synaptosomal fractions

Indexed keywords

3 NITROPROPIONIC ACID; CARNITINE; QUINOLINIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN SYNAPTOSOME; CELL ENERGY; CONTROLLED STUDY; DRUG MECHANISM; EXCITOTOXICITY; LIPID PEROXIDATION; MALE; NERVE DEGENERATION; NERVE ENDING; NEUROTOXICITY; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

ANIMALS; ANTIOXIDANTS; BRAIN; CARNITINE; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENERGY METABOLISM; ENZYME INHIBITORS; MALE; MITOCHONDRIA; NEUROTOXINS; NITRO COMPOUNDS; OXIDANTS; OXIDATION-REDUCTION; OXIDATIVE STRESS; PRESYNAPTIC TERMINALS; PROPIONIC ACIDS; QUINOLINIC ACID; RATS; RATS, WISTAR; SYNAPTOSOMES; VITAMIN B COMPLEX;

EID: 70349587923     PISSN: 00144819     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00221-009-1913-3     Document Type: Article

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