Silencing of C5a receptor gene with siRNA for protection from Gram-negative bacterial lipopolysaccharide-induced vascular permeability

Molecular Immunology

Volumn 47, Issue 6, 2010, Pages 1325-1333

  Liu, Zi ming ^a   Zhu, Shi ming ^b   Qin, Xiang jing ^b   Cheng, Zhi de ^b   Liu, Meng yuan ^b   Zhang, Hai mou ^b   Liu, Dong xu ^b  

^a SICHUAN UNIVERSITY   (China)

^b HUBEI UNIVERSITY   (China)

Author keywords

C5aR; Inflammation; RNA interference; Sepsis; Vascular permeability

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; COMPLEMENT COMPONENT C5A RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1; PROTEIN KINASE C DELTA; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR RELA; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL IMMUNITY; BLOOD VESSEL PERMEABILITY; CONTROLLED STUDY; CYTOSKELETON; DRUG MECHANISM; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME INDUCTION; ENZYME INHIBITION; GENE EXPRESSION REGULATION; GENE SILENCING; MOUSE; NONHUMAN; PRIMARY PREVENTION; PRIORITY JOURNAL; PROTECTION; RNA INTERFERENCE; UPREGULATION;

ANIMALS; CAPILLARY PERMEABILITY; CELL NUCLEUS; ENDOTHELIUM, VASCULAR; GENE KNOCKDOWN TECHNIQUES; GENE SILENCING; GRAM-NEGATIVE BACTERIA; I-KAPPA B KINASE; I-KAPPA B PROTEINS; LIPOPOLYSACCHARIDES; MAP KINASE SIGNALING SYSTEM; MICE; MICROVESSELS; NF-KAPPA B P50 SUBUNIT; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN TRANSPORT; RECEPTOR, ANAPHYLATOXIN C5A; RNA, SMALL INTERFERING; SKIN; TRANSCRIPTION FACTOR RELA; VASCULAR CELL ADHESION MOLECULE-1;

BACTERIA (MICROORGANISMS); MUS; NEGIBACTERIA;

EID: 76949088249     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2009.11.001     Document Type: Article

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