메뉴 건너뛰기




Volumn 392, Issue 4, 2010, Pages 526-532

Transcription factor AP-2β: A negative regulator of IRS-1 gene expression

Author keywords

3T3 L1 adipocytes; AP 2 ; Insulin resistance; IRS 1; Type 2 diabetes

Indexed keywords

ADIPOCYTOKINE; INSULIN RECEPTOR SUBSTRATE 1; INTERLEUKIN 6; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; TRANSCRIPTION FACTOR AP 2; TRANSCRIPTION FACTOR AP 2BETA; UNCLASSIFIED DRUG;

EID: 76749168404     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.01.056     Document Type: Article
Times cited : (21)

References (33)
  • 1
    • 0035856920 scopus 로고    scopus 로고
    • Global and societal implications of the diabetes epidemic
    • Zimmet P., Alberti K.G., and Shaw J. Global and societal implications of the diabetes epidemic. Nature 414 (2001) 782-787
    • (2001) Nature , vol.414 , pp. 782-787
    • Zimmet, P.1    Alberti, K.G.2    Shaw, J.3
  • 2
    • 0032489358 scopus 로고    scopus 로고
    • Type 2 diabetes: when insulin secretion fails to compensate for insulin resistance
    • Kahn B.B. Type 2 diabetes: when insulin secretion fails to compensate for insulin resistance. Cell 92 (1998) 593-596
    • (1998) Cell , vol.92 , pp. 593-596
    • Kahn, B.B.1
  • 3
    • 0035936763 scopus 로고    scopus 로고
    • New perspectives into the molecular pathogenesis and treatment of type 2 diabetes
    • Saltiel A.R. New perspectives into the molecular pathogenesis and treatment of type 2 diabetes. Cell 104 (2001) 517-529
    • (2001) Cell , vol.104 , pp. 517-529
    • Saltiel, A.R.1
  • 4
    • 0035316142 scopus 로고    scopus 로고
    • Insulin resistance with low cellular IRS-1 expression is also associated with low GLUT4 expression and impaired insulin-stimulated glucose transport
    • Carvalho E., Jansson P.A., Nagaev I., et al. Insulin resistance with low cellular IRS-1 expression is also associated with low GLUT4 expression and impaired insulin-stimulated glucose transport. FASEB J. 15 (2001) 1101-1103
    • (2001) FASEB J. , vol.15 , pp. 1101-1103
    • Carvalho, E.1    Jansson, P.A.2    Nagaev, I.3
  • 5
    • 0030890580 scopus 로고    scopus 로고
    • Insulin receptor substrate (IRS) 1 is reduced and IRS-2 is the main docking protein for phosphatidylinositol 3-kinase in adipocytes from subjects with non-insulin-dependent diabetes mellitus
    • Rondinone C.M., Wang L.M., Lonnroth P., et al. Insulin receptor substrate (IRS) 1 is reduced and IRS-2 is the main docking protein for phosphatidylinositol 3-kinase in adipocytes from subjects with non-insulin-dependent diabetes mellitus. Proc. Natl. Acad. Sci. USA 94 (1997) 4171-4175
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 4171-4175
    • Rondinone, C.M.1    Wang, L.M.2    Lonnroth, P.3
  • 6
    • 0031984952 scopus 로고    scopus 로고
    • Altered expression levels and impaired steps in the pathway to phosphatidylinositol 3-kinase activation via insulin receptor substrates 1 and 2 in Zucker fatty rats
    • Anai M., Funaki M., Ogihara T., et al. Altered expression levels and impaired steps in the pathway to phosphatidylinositol 3-kinase activation via insulin receptor substrates 1 and 2 in Zucker fatty rats. Diabetes 47 (1998) 13-23
    • (1998) Diabetes , vol.47 , pp. 13-23
    • Anai, M.1    Funaki, M.2    Ogihara, T.3
  • 7
    • 2642683510 scopus 로고    scopus 로고
    • Differential regulation of insulin receptor substrates-1 and -2 (IRS-1 and IRS-2) and phosphatidylinositol 3-kinase isoforms in liver and muscle of the obese diabetic (ob/ob) mouse
    • Kerouz N.J., Horsch D., Pons S., et al. Differential regulation of insulin receptor substrates-1 and -2 (IRS-1 and IRS-2) and phosphatidylinositol 3-kinase isoforms in liver and muscle of the obese diabetic (ob/ob) mouse. J. Clin. Invest. 100 (1997) 3164-3172
    • (1997) J. Clin. Invest. , vol.100 , pp. 3164-3172
    • Kerouz, N.J.1    Horsch, D.2    Pons, S.3
  • 8
    • 64349124502 scopus 로고    scopus 로고
    • Glucose transporter 4 and insulin receptor substrate-1 messenger RNA expression in omental and subcutaneous adipose tissue in women
    • Veilleux A., Blouin K., Rheaume C., et al. Glucose transporter 4 and insulin receptor substrate-1 messenger RNA expression in omental and subcutaneous adipose tissue in women. Metabolism 58 (2009) 624-631
    • (2009) Metabolism , vol.58 , pp. 624-631
    • Veilleux, A.1    Blouin, K.2    Rheaume, C.3
  • 9
    • 0037059330 scopus 로고    scopus 로고
    • Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action
    • Aguirre V., Werner E.D., Giraud J., et al. Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action. J. Biol. Chem. 277 (2002) 1531-1537
    • (2002) J. Biol. Chem. , vol.277 , pp. 1531-1537
    • Aguirre, V.1    Werner, E.D.2    Giraud, J.3
  • 10
    • 4544343980 scopus 로고    scopus 로고
    • Inappropriate activation of the TSC/Rheb/mTOR/S6K cassette induces IRS1/2 depletion, insulin resistance, and cell survival deficiencies
    • Shah O.J., Wang Z., and Hunter T. Inappropriate activation of the TSC/Rheb/mTOR/S6K cassette induces IRS1/2 depletion, insulin resistance, and cell survival deficiencies. Curr. Biol. 14 (2004) 1650-1656
    • (2004) Curr. Biol. , vol.14 , pp. 1650-1656
    • Shah, O.J.1    Wang, Z.2    Hunter, T.3
  • 11
    • 0036830636 scopus 로고    scopus 로고
    • SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2
    • Rui L., Yuan M., Frantz D., et al. SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2. J. Biol. Chem. 277 (2002) 42394-42398
    • (2002) J. Biol. Chem. , vol.277 , pp. 42394-42398
    • Rui, L.1    Yuan, M.2    Frantz, D.3
  • 12
    • 14544271905 scopus 로고    scopus 로고
    • Positive and negative regulation of insulin signaling through IRS-1 phosphorylation
    • Gual P., Le Marchand-Brustel Y., and Tanti J.F. Positive and negative regulation of insulin signaling through IRS-1 phosphorylation. Biochimie 87 (2005) 99-109
    • (2005) Biochimie , vol.87 , pp. 99-109
    • Gual, P.1    Le Marchand-Brustel, Y.2    Tanti, J.F.3
  • 13
    • 23844472598 scopus 로고    scopus 로고
    • Genetic variations in the gene encoding TFAP2B are associated with type 2 diabetes mellitus
    • Maeda S., Tsukada S., Kanazawa A., et al. Genetic variations in the gene encoding TFAP2B are associated with type 2 diabetes mellitus. J. Hum. Genet. 50 (2005) 283-292
    • (2005) J. Hum. Genet. , vol.50 , pp. 283-292
    • Maeda, S.1    Tsukada, S.2    Kanazawa, A.3
  • 14
    • 67651236725 scopus 로고    scopus 로고
    • Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution
    • Lindgren C.M., Heid I.M., Randall J.C., et al. Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet. 5 (2009) e1000508
    • (2009) PLoS Genet. , vol.5
    • Lindgren, C.M.1    Heid, I.M.2    Randall, J.C.3
  • 15
    • 69749102466 scopus 로고    scopus 로고
    • The transcription factor TFAP2B is associated with insulin resistance and adiposity in healthy adolescents
    • Nordquist N., Gokturk C., Comasco E., et al. The transcription factor TFAP2B is associated with insulin resistance and adiposity in healthy adolescents. Obesity (Silver Spring) 17 (2009) 1762-1767
    • (2009) Obesity (Silver Spring) , vol.17 , pp. 1762-1767
    • Nordquist, N.1    Gokturk, C.2    Comasco, E.3
  • 16
    • 33845978428 scopus 로고    scopus 로고
    • Transcription factor activating enhancer-binding protein-2beta. A negative regulator of adiponectin gene expression
    • Ikeda K., Maegawa H., Ugi S., et al. Transcription factor activating enhancer-binding protein-2beta. A negative regulator of adiponectin gene expression. J. Biol. Chem. 281 (2006) 31245-31253
    • (2006) J. Biol. Chem. , vol.281 , pp. 31245-31253
    • Ikeda, K.1    Maegawa, H.2    Ugi, S.3
  • 17
    • 77950866139 scopus 로고    scopus 로고
    • Transcription factor AP-2β inhibits expression and secression of leptin, an insulin-sensitizing hormone, in 3T3-L1 adipocytes
    • 10.1038/ijo.2009.295
    • Fuke T., Yoshizaki T., Kondo M., et al. Transcription factor AP-2β inhibits expression and secression of leptin, an insulin-sensitizing hormone, in 3T3-L1 adipocytes. Int. J. Obes. (Lond.) (2009) 10.1038/ijo.2009.295
    • (2009) Int. J. Obes. (Lond.)
    • Fuke, T.1    Yoshizaki, T.2    Kondo, M.3
  • 18
    • 63849109129 scopus 로고    scopus 로고
    • Transcription factor activating protein-2beta: a positive regulator of monocyte chemoattractant protein-1 gene expression
    • Kondo M., Maegawa H., Obata T., et al. Transcription factor activating protein-2beta: a positive regulator of monocyte chemoattractant protein-1 gene expression. Endocrinology 150 (2009) 1654-1661
    • (2009) Endocrinology , vol.150 , pp. 1654-1661
    • Kondo, M.1    Maegawa, H.2    Obata, T.3
  • 19
    • 77954143887 scopus 로고    scopus 로고
    • Relationship between the expression of transcriptional factor TFAP2B and that of adipokines in subcutaneous and omental adipose tissues
    • 10.1038/oby.2009.442
    • Ugi S., Nishio Y., Yamamoto H., et al. Relationship between the expression of transcriptional factor TFAP2B and that of adipokines in subcutaneous and omental adipose tissues. Obesity (Silver Spring) (2009) 10.1038/oby.2009.442
    • (2009) Obesity (Silver Spring)
    • Ugi, S.1    Nishio, Y.2    Yamamoto, H.3
  • 20
    • 33645507246 scopus 로고    scopus 로고
    • The transcription factor AP-2beta causes cell enlargement and insulin resistance in 3T3-L1 adipocytes
    • Tao Y., Maegawa H., Ugi S., et al. The transcription factor AP-2beta causes cell enlargement and insulin resistance in 3T3-L1 adipocytes. Endocrinology 147 (2006) 1685-1696
    • (2006) Endocrinology , vol.147 , pp. 1685-1696
    • Tao, Y.1    Maegawa, H.2    Ugi, S.3
  • 21
    • 4544314719 scopus 로고    scopus 로고
    • Protein phosphatase 2A negatively regulates insulin's metabolic signaling pathway by inhibiting Akt (protein kinase B) activity in 3T3-L1 adipocytes
    • Ugi S., Imamura T., Maegawa H., et al. Protein phosphatase 2A negatively regulates insulin's metabolic signaling pathway by inhibiting Akt (protein kinase B) activity in 3T3-L1 adipocytes. Mol. Cell. Biol. 24 (2004) 8778-8789
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 8778-8789
    • Ugi, S.1    Imamura, T.2    Maegawa, H.3
  • 22
    • 0033553415 scopus 로고    scopus 로고
    • Membrane-targeted phosphatidylinositol 3-kinase mimics insulin actions and induces a state of cellular insulin resistance
    • Egawa K., Sharma P.M., Nakashima N., et al. Membrane-targeted phosphatidylinositol 3-kinase mimics insulin actions and induces a state of cellular insulin resistance. J. Biol. Chem. 274 (1999) 14306-14314
    • (1999) J. Biol. Chem. , vol.274 , pp. 14306-14314
    • Egawa, K.1    Sharma, P.M.2    Nakashima, N.3
  • 23
    • 0029096089 scopus 로고
    • Characterization and regulation of the mouse insulin receptor substrate gene promoter
    • Araki E., Haag III B.L., Matsuda K., et al. Characterization and regulation of the mouse insulin receptor substrate gene promoter. Mol. Endocrinol. 9 (1995) 1367-1379
    • (1995) Mol. Endocrinol. , vol.9 , pp. 1367-1379
    • Araki, E.1    Haag III, B.L.2    Matsuda, K.3
  • 24
    • 12544256299 scopus 로고    scopus 로고
    • Regulation of ATP-sensitive potassium channel subunit Kir6.2 expression in rat intestinal insulin-producing progenitor cells
    • Hashimoto T., Nakamura T., Maegawa H., et al. Regulation of ATP-sensitive potassium channel subunit Kir6.2 expression in rat intestinal insulin-producing progenitor cells. J. Biol. Chem. 280 (2005) 1893-1900
    • (2005) J. Biol. Chem. , vol.280 , pp. 1893-1900
    • Hashimoto, T.1    Nakamura, T.2    Maegawa, H.3
  • 25
    • 0034022637 scopus 로고    scopus 로고
    • Mutations in TFAP2B cause Char syndrome, a familial form of patent ductus arteriosus
    • Satoda M., Zhao F., Diaz G.A., et al. Mutations in TFAP2B cause Char syndrome, a familial form of patent ductus arteriosus. Nat. Genet. 25 (2000) 42-46
    • (2000) Nat. Genet. , vol.25 , pp. 42-46
    • Satoda, M.1    Zhao, F.2    Diaz, G.A.3
  • 26
    • 0034836484 scopus 로고    scopus 로고
    • Novel TFAP2B mutations that cause Char syndrome provide a genotype-phenotype correlation
    • Zhao F., Weismann C.G., Satoda M., et al. Novel TFAP2B mutations that cause Char syndrome provide a genotype-phenotype correlation. Am. J. Hum. Genet. 69 (2001) 695-703
    • (2001) Am. J. Hum. Genet. , vol.69 , pp. 695-703
    • Zhao, F.1    Weismann, C.G.2    Satoda, M.3
  • 27
    • 0024199329 scopus 로고
    • Cloning and expression of AP-2, a cell-type-specific transcription factor that activates inducible enhancer elements
    • Williams T., Admon A., Luscher B., et al. Cloning and expression of AP-2, a cell-type-specific transcription factor that activates inducible enhancer elements. Genes Dev. 2 (1988) 1557-1569
    • (1988) Genes Dev. , vol.2 , pp. 1557-1569
    • Williams, T.1    Admon, A.2    Luscher, B.3
  • 28
    • 0035798538 scopus 로고    scopus 로고
    • Cloning and characterization of a novel mouse AP-2 transcription factor, AP-2delta, with unique DNA binding and transactivation properties
    • Zhao F., Satoda M., Licht J.D., et al. Cloning and characterization of a novel mouse AP-2 transcription factor, AP-2delta, with unique DNA binding and transactivation properties. J. Biol. Chem. 276 (2001) 40755-40760
    • (2001) J. Biol. Chem. , vol.276 , pp. 40755-40760
    • Zhao, F.1    Satoda, M.2    Licht, J.D.3
  • 29
    • 0029119180 scopus 로고
    • Cloning and characterization of a second AP-2 transcription factor: AP-2 beta
    • Moser M., Imhof A., Pscherer A., et al. Cloning and characterization of a second AP-2 transcription factor: AP-2 beta. Development 121 (1995) 2779-2788
    • (1995) Development , vol.121 , pp. 2779-2788
    • Moser, M.1    Imhof, A.2    Pscherer, A.3
  • 30
    • 0032779156 scopus 로고    scopus 로고
    • Low cellular IRS 1 gene and protein expression predict insulin resistance and NIDDM
    • Carvalho E., Jansson P.A., Axelsen M., et al. Low cellular IRS 1 gene and protein expression predict insulin resistance and NIDDM. FASEB J. 13 (1999) 2173-2178
    • (1999) FASEB J. , vol.13 , pp. 2173-2178
    • Carvalho, E.1    Jansson, P.A.2    Axelsen, M.3
  • 31
    • 14544269997 scopus 로고    scopus 로고
    • Differential gene expression of insulin receptor isoforms A and B and insulin receptor substrates 1, 2 and 3 in rat tissues: modulation by aging and differentiation in rat adipose tissue
    • Serrano R., Villar M., Martinez C., et al. Differential gene expression of insulin receptor isoforms A and B and insulin receptor substrates 1, 2 and 3 in rat tissues: modulation by aging and differentiation in rat adipose tissue. J. Mol. Endocrinol. 34 (2005) 153-161
    • (2005) J. Mol. Endocrinol. , vol.34 , pp. 153-161
    • Serrano, R.1    Villar, M.2    Martinez, C.3
  • 32
    • 70349557826 scopus 로고    scopus 로고
    • Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia
    • Rung J., Cauchi S., Albrechtsen A., et al. Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia. Nat. Genet. 41 (2009) 1110-1115
    • (2009) Nat. Genet. , vol.41 , pp. 1110-1115
    • Rung, J.1    Cauchi, S.2    Albrechtsen, A.3
  • 33
    • 0344412860 scopus 로고    scopus 로고
    • The role of insulin receptor substrate-1 gene (IRS1) in type 2 diabetes in Pima Indians
    • Kovacs P., Hanson R.L., Lee Y.H., et al. The role of insulin receptor substrate-1 gene (IRS1) in type 2 diabetes in Pima Indians. Diabetes 52 (2003) 3005-3009
    • (2003) Diabetes , vol.52 , pp. 3005-3009
    • Kovacs, P.1    Hanson, R.L.2    Lee, Y.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.