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Volumn 31, Issue 1, 2010, Pages 87-96

Liberation and animation: Strategies to minimize brain dysfunction in critically ill patients

Author keywords

Delirium; Long term cognitive impairment; Sedation

Indexed keywords

BENZODIAZEPINE; DEXMEDETOMIDINE; FENTANYL; PROPOFOL; REMIFENTANIL; SEDATIVE AGENT;

EID: 76749158943     PISSN: 10693424     EISSN: 10989048     Source Type: Journal    
DOI: 10.1055/s-0029-1246284     Document Type: Review
Times cited : (17)

References (66)
  • 4
    • 0035023645 scopus 로고    scopus 로고
    • Intensive care delirium screening checklist: Evaluation of a new screening tool
    • Bergeron N, Dubois M-J, Dumont M, Dial S, Skrobik Y. Intensive Care Delirium Screening Checklist: evaluation of a new screening tool. Intensive Care Med 2001 27 859-864
    • (2001) Intensive Care Med , vol.27 , pp. 859-864
    • Bergeron, N.1    Dubois, M.-J.2    Dumont, M.3    Dial, S.4    Skrobik, Y.5
  • 6
    • 52949116805 scopus 로고    scopus 로고
    • Understanding international differences in terminology for delirium and other types of acute brain dysfunction in critically ill patients
    • Morandi A, Pandharipande P, Trabucchi M et al. Understanding international differences in terminology for delirium and other types of acute brain dysfunction in critically ill patients. Intensive Care Med 2008 34 1907-1915
    • (2008) Intensive Care Med , vol.34 , pp. 1907-1915
    • Morandi, A.1    Pandharipande, P.2    Trabucchi, M.3
  • 7
    • 1842867052 scopus 로고    scopus 로고
    • Delirium as a predictor of mortality in mechanically ventilated patients in the intensive care unit
    • Ely E W., Shintani A, Truman B et al. Delirium as a predictor of mortality in mechanically ventilated patients in the intensive care unit. JAMA 2004 291 1753-1762
    • (2004) JAMA , vol.291 , pp. 1753-1762
    • Ely, E.W.1    Shintani, A.2    Truman, B.3
  • 8
    • 11144358457 scopus 로고    scopus 로고
    • Costs associated with delirium in mechanically ventilated patients
    • Milbrandt E B., Deppen S, Harrison P L. et al. Costs associated with delirium in mechanically ventilated patients. Crit Care Med 2004 32 955-962
    • (2004) Crit Care Med , vol.32 , pp. 955-962
    • Milbrandt, E.B.1    Deppen, S.2    Harrison, P.L.3
  • 9
    • 76749096827 scopus 로고    scopus 로고
    • Critical care medicine in the United States 20002005: An analysis of bed numbers, occupancy rates, payer mix, and costs
    • 2009 Aug 27. [Epub ahead of print]
    • Halpern N A., Pastores S M. Critical care medicine in the United States 20002005: an analysis of bed numbers, occupancy rates, payer mix, and costs. Crit Care Med 2005 2009 Aug 27. [Epub ahead of print]
    • (2005) Crit Care Med
    • Halpern, N.A.1    Pastores, S.M.2
  • 10
    • 3543025110 scopus 로고    scopus 로고
    • The association between delirium and cognitive decline: A review of the empirical literature
    • Jackson J C., Gordon S M., Hart R P., Hopkins R O., Ely E W. The association between delirium and cognitive decline: a review of the empirical literature. Neuropsychol Rev 2004 14 87-98
    • (2004) Neuropsychol Rev , vol.14 , pp. 87-98
    • Jackson, J.C.1    Gordon, S.M.2    Hart, R.P.3    Hopkins, R.O.4    Ely, E.W.5
  • 12
    • 0035210918 scopus 로고    scopus 로고
    • The impact of delirium in the intensive care unit on hospital length of stay
    • Ely E W., Gautam S, Margolin R et al. The impact of delirium in the intensive care unit on hospital length of stay. Intensive Care Med 2001 27 1892-1900
    • (2001) Intensive Care Med , vol.27 , pp. 1892-1900
    • Ely, E.W.1    Gautam, S.2    Margolin, R.3
  • 14
    • 0032795197 scopus 로고    scopus 로고
    • Neuropsychological sequelae and impaired health status in survivors of severe acute respiratory distress syndrome
    • Hopkins R O., Weaver L K., Pope D, Orme J F., Bigler E D., Larson-LOHR V. Neuropsychological sequelae and impaired health status in survivors of severe acute respiratory distress syndrome. Am J Respir Crit Care Med 1999 160 50-56
    • (1999) Am J Respir Crit Care Med , vol.160 , pp. 50-56
    • Hopkins, R.O.1    Weaver, L.K.2    Pope, D.3    Orme, J.F.4    Bigler, E.D.5    Larson-Lohr, V.6
  • 15
    • 0035055620 scopus 로고    scopus 로고
    • The relationship between cognitive performance and employment and health status in long-term survivors of the acute respiratory distress syndrome: Results of an exploratory study
    • Rothenhausler H B., Ehrentraut S, Stoll C, Schelling G, Kapfhammer H P. The relationship between cognitive performance and employment and health status in long-term survivors of the acute respiratory distress syndrome: results of an exploratory study. Gen Hosp Psychiatry 2001 23 90-96
    • (2001) Gen Hosp Psychiatry , vol.23 , pp. 90-96
    • Rothenhausler, H.B.1    Ehrentraut, S.2    Stoll, C.3    Schelling, G.4    Kapfhammer, H.P.5
  • 16
    • 0037348476 scopus 로고    scopus 로고
    • Surviving intensive care: A report from the 2002 Brussels Roundtable
    • 2002 Brussels Roundtable Participants
    • Angus D C., Carlet J, 2002 Brussels Roundtable Participants. Surviving intensive care: a report from the 2002 Brussels Roundtable. Intensive Care Med 2003 29 368-377
    • (2003) Intensive Care Med , vol.29 , pp. 368-377
    • Angus, D.C.1    Carlet, J.2
  • 17
    • 33644999491 scopus 로고    scopus 로고
    • Brain atrophy and cognitive impairment in survivors of acute respiratory distress syndrome
    • Hopkins R O., Gale S D., Weaver L K. Brain atrophy and cognitive impairment in survivors of acute respiratory distress syndrome. Brain Inj 2006 20 263-271
    • (2006) Brain Inj , vol.20 , pp. 263-271
    • Hopkins, R.O.1    Gale, S.D.2    Weaver, L.K.3
  • 20
    • 8544281694 scopus 로고    scopus 로고
    • The impact of delirium on the survival of mechanically ventilated patients
    • Lin S M., Liu C Y., Wang C H. et al. The impact of delirium on the survival of mechanically ventilated patients. Crit Care Med 2004 32 2254-2259
    • (2004) Crit Care Med , vol.32 , pp. 2254-2259
    • Lin, S.M.1    Liu, C.Y.2    Wang, C.H.3
  • 22
    • 72749113044 scopus 로고    scopus 로고
    • Days of delirium are associated with 1-year mortality in an older intensive care unit population
    • Sep 10. [Epub ahead of print]
    • Pisani M A., Kong S Y., Kasl S V., Murphy T E., Araujo K L., Van Ness P H. Days of delirium are associated with 1-year mortality in an older intensive care unit population. Am J Respir Crit Care Med 2009 Sep 10. [Epub ahead of print]
    • (2009) Am J Respir Crit Care Med
    • Pisani, M.A.1    Kong, S.Y.2    Kasl, S.V.3    Murphy, T.E.4    Araujo, K.L.5    Van Ness, P.H.6
  • 23
    • 67649974294 scopus 로고    scopus 로고
    • Prevalence and risk factors for development of delirium in surgical and trauma intensive care unit patients
    • Pandharipande P, Cotton B A., Shintani A et al. Prevalence and risk factors for development of delirium in surgical and trauma intensive care unit patients. J Trauma 2008 65 34-41
    • (2008) J Trauma , vol.65 , pp. 34-41
    • Pandharipande, P.1    Cotton, B.A.2    Shintani, A.3
  • 24
    • 33644851831 scopus 로고    scopus 로고
    • Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients
    • Pandharipande P, Shintani A, Peterson J et al. Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients. Anesthesiology 2006 104 21-26
    • (2006) Anesthesiology , vol.104 , pp. 21-26
    • Pandharipande, P.1    Shintani, A.2    Peterson, J.3
  • 25
    • 0037111193 scopus 로고    scopus 로고
    • The Richmond Agitation-Sedation Scale: Validity and reliability in adult intensive care unit patients
    • Sessler C N., Gosnell M S., Grap M J. et al. The Richmond Agitation-Sedation Scale: validity and reliability in adult intensive care unit patients. Am J Respir Crit Care Med 2002 166 1338-1344
    • (2002) Am J Respir Crit Care Med , vol.166 , pp. 1338-1344
    • Sessler, C.N.1    Gosnell, M.S.2    Grap, M.J.3
  • 26
    • 0016400110 scopus 로고
    • Controlled sedation with alphaxalone-alphadolone
    • Ramsay M A., Savege T M., Simpson B R., Goodwin R. Controlled sedation with alphaxalone-alphadolone. BMJ 1974 2 656-659
    • (1974) BMJ , vol.2 , pp. 656-659
    • Ramsay, M.A.1    Savege, T.M.2    Simpson, B.R.3    Goodwin, R.4
  • 28
    • 0033400647 scopus 로고    scopus 로고
    • Effect of a nursing-implemented sedation protocol on the duration of mechanical ventilation
    • Brook A D., Ahrens T S., Schaiff R et al. Effect of a nursing-implemented sedation protocol on the duration of mechanical ventilation. Crit Care Med 1999 27 2609-2615
    • (1999) Crit Care Med , vol.27 , pp. 2609-2615
    • Brook, A.D.1    Ahrens, T.S.2    Schaiff, R.3
  • 29
    • 0028648285 scopus 로고
    • Cost of ICU sedation: Comparison of empirical and controlled sedation methods
    • Costa J, Cabré L, Molina R, Carrasco G. Cost of ICU sedation: comparison of empirical and controlled sedation methods. Clin Intensive Care 1994 5 (5, Suppl) 17-21
    • (1994) Clin Intensive Care , vol.5 , Issue.5 SUPPL , pp. 17-21
    • Costa, J.1    Cabré, L.2    Molina, R.3    Carrasco, G.4
  • 30
    • 0033861716 scopus 로고    scopus 로고
    • Pharmacoeconomic impact of rational use guidelines on the provision of analgesia, sedation, and neuromuscular blockade in critical care
    • Mascia M F., Koch M, Medicis J J. Pharmacoeconomic impact of rational use guidelines on the provision of analgesia, sedation, and neuromuscular blockade in critical care. Crit Care Med 2000 28 2300-2306
    • (2000) Crit Care Med , vol.28 , pp. 2300-2306
    • Mascia, M.F.1    Koch, M.2    Medicis, J.J.3
  • 31
    • 3242667280 scopus 로고    scopus 로고
    • Effect of a scoring system and protocol for sedation on duration of patients' need for ventilator support in a surgical intensive care unit
    • Brattebø G, Hofoss D, Flaatten H, Muri A K., Gjerde S, Plsek P E. Effect of a scoring system and protocol for sedation on duration of patients' need for ventilator support in a surgical intensive care unit. Qual Saf Health Care 2004 13 203-205
    • (2004) Qual Saf Health Care , vol.13 , pp. 203-205
    • Brattebø, G.1    Hofoss, D.2    Flaatten, H.3    Muri, A.K.4    Gjerde, S.5    Plsek, P.E.6
  • 32
    • 34548209930 scopus 로고    scopus 로고
    • Effect of a nurse-implemented sedation protocol on the incidence of ventilator-associated pneumonia
    • Quenot J P., Ladoire S, Devoucoux F et al. Effect of a nurse-implemented sedation protocol on the incidence of ventilator-associated pneumonia. Crit Care Med 2007 35 2031-2036
    • (2007) Crit Care Med , vol.35 , pp. 2031-2036
    • Quenot, J.P.1    Ladoire, S.2    Devoucoux, F.3
  • 33
    • 47249093277 scopus 로고    scopus 로고
    • Effect of a nursing-implemented sedation protocol on weaning outcome
    • Arias-Rivera S, Snchez-Snchez MdelM, Santos-Daz R et al. Effect of a nursing-implemented sedation protocol on weaning outcome. Crit Care Med 2008 36 2054-2060
    • (2008) Crit Care Med , vol.36 , pp. 2054-2060
    • Arias-Rivera, S.1    Snchez-Snchez, M.2    Santos-Daz, R.3
  • 34
    • 42949170527 scopus 로고    scopus 로고
    • A randomized trial of protocol-directed sedation management for mechanical ventilation in an Australian intensive care unit
    • Bucknall T K., Manias E, Presneill J J. A randomized trial of protocol-directed sedation management for mechanical ventilation in an Australian intensive care unit. Crit Care Med 2008 36 1444-1450
    • (2008) Crit Care Med , vol.36 , pp. 1444-1450
    • Bucknall, T.K.1    Manias, E.2    Presneill, J.J.3
  • 36
    • 47149103057 scopus 로고    scopus 로고
    • Impact of the use of propofol remifentanil goal-directed sedation adapted by nurses on the tie to extubation in mechanically ventilated ICU patients: The experience of a French ICU
    • Epub 2008 June 26
    • Muller L, Chanques G, Bourgaux C et al. Impact of the use of propofol remifentanil goal-directed sedation adapted by nurses on the tie to extubation in mechanically ventilated ICU patients: the experience of a French ICU. Ann Fr Anesth Reanim 2008 27 481.e1-e8 Epub 2008 June 26
    • (2008) Ann Fr Anesth Reanim , vol.27
    • Muller, L.1    Chanques, G.2    Bourgaux, C.3
  • 37
    • 33749246266 scopus 로고    scopus 로고
    • The effect of an algorithm-based sedation guideline on the duration of mechanical ventilation in an Australian intensive care unit
    • Elliott R, McKinley S, Aitken L M., Hendrikz J. The effect of an algorithm-based sedation guideline on the duration of mechanical ventilation in an Australian intensive care unit. Intensive Care Med 2006 32 1506-1514
    • (2006) Intensive Care Med , vol.32 , pp. 1506-1514
    • Elliott, R.1    McKinley, S.2    Aitken, L.M.3    Hendrikz, J.4
  • 38
    • 12244286756 scopus 로고    scopus 로고
    • Sedation algorithm in critically ill patients without acute brain injury
    • De Jonghe B, Bastuji-Garin S, Fangio P et al. Sedation algorithm in critically ill patients without acute brain injury. Crit Care Med 2005 33 120-127
    • (2005) Crit Care Med , vol.33 , pp. 120-127
    • De Jonghe, B.1    Bastuji-Garin, S.2    Fangio, P.3
  • 39
    • 33744504895 scopus 로고    scopus 로고
    • Impact of systematic evaluation of pain and agitation in an intensive care unit
    • Chanques G, Jaber S, Barbotte E et al. Impact of systematic evaluation of pain and agitation in an intensive care unit. Crit Care Med 2006 34 1691-1699
    • (2006) Crit Care Med , vol.34 , pp. 1691-1699
    • Chanques, G.1    Jaber, S.2    Barbotte, E.3
  • 40
    • 0034682246 scopus 로고    scopus 로고
    • Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation
    • Kress J P., Pohlman A S., O'Connor M F., Hall J B. Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation. N Engl J Med 2000 342 1471-1477
    • (2000) N Engl J Med , vol.342 , pp. 1471-1477
    • Kress, J.P.1    Pohlman, A.S.2    O'Connor, M.F.3    Hall, J.B.4
  • 41
    • 4544299667 scopus 로고    scopus 로고
    • Survey of routines for sedation of patients on controlled ventilation in Nordic intensive care units
    • Scandinavian Critical Care Trials Group
    • Guldbrand P, Berggren L, Brattebö G, Mälstam J, Rönholm E, Winsö O, Scandinavian Critical Care Trials Group. Survey of routines for sedation of patients on controlled ventilation in Nordic intensive care units. Acta Anaesthesiol Scand 2004 48 944-950
    • (2004) Acta Anaesthesiol Scand , vol.48 , pp. 944-950
    • Guldbrand, P.1    Berggren, L.2    Brattebö, G.3    Mälstam, J.4    Rönholm, E.5    Winsö, O.6
  • 42
    • 58149520472 scopus 로고    scopus 로고
    • Sedation practice in the intensive care unit: A UK national survey
    • Reschreiter H, Maiden M, Kapila A. Sedation practice in the intensive care unit: a UK national survey. Crit Care 2008 12 R152
    • (2008) Crit Care , vol.12
    • Reschreiter, H.1    Maiden, M.2    Kapila, A.3
  • 44
    • 38049017332 scopus 로고    scopus 로고
    • Efficacy and safety of a paired sedation and ventilator weaning protocol for mechanically ventilated patients in intensive care (Awakening and Breathing Controlled trial): A randomised controlled trial
    • Girard T D., Kress J P., Fuchs B D. et al. Efficacy and safety of a paired sedation and ventilator weaning protocol for mechanically ventilated patients in intensive care (Awakening and Breathing Controlled trial): a randomised controlled trial. Lancet 2008 371 126-134
    • (2008) Lancet , vol.371 , pp. 126-134
    • Girard, T.D.1    Kress, J.P.2    Fuchs, B.D.3
  • 45
    • 72249105873 scopus 로고    scopus 로고
    • Use of intravenous infusion sedation among mechanically ventilated patients in the United States
    • Jul 23 [Epub ahead of print]
    • Wunsch H, Kahn J M., Kramer A A., Rubenfeld G D. Use of intravenous infusion sedation among mechanically ventilated patients in the United States. Crit Care Med 2009 Jul 23 [Epub ahead of print]
    • (2009) Crit Care Med
    • Wunsch, H.1    Kahn, J.M.2    Kramer, A.A.3    Rubenfeld, G.D.4
  • 46
    • 0347061065 scopus 로고    scopus 로고
    • National survey of the use of sedating drugs, neuromuscular blocking agents, and reversal agents in the intensive care unit
    • Rhoney D H., Murry K R. National survey of the use of sedating drugs, neuromuscular blocking agents, and reversal agents in the intensive care unit. J Intensive Care Med 2003 18 139-145
    • (2003) J Intensive Care Med , vol.18 , pp. 139-145
    • Rhoney, D.H.1    Murry, K.R.2
  • 47
    • 37149040245 scopus 로고    scopus 로고
    • Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: The MENDS randomized controlled trial
    • Pandharipande P P., Pun B T., Herr D L. et al. Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial. JAMA 2007 298 2644-2653
    • (2007) JAMA , vol.298 , pp. 2644-2653
    • Pandharipande, P.P.1    Pun, B.T.2    Herr, D.L.3
  • 48
    • 59649127447 scopus 로고    scopus 로고
    • Dexmedetomidine vs midazolam for sedation of critically ill patients: A randomized trial
    • SEDCOM (Safety and Efficacy of Dexmedetomidine Compared With Midazolam) Study Group
    • Riker R R., Shehabi Y, Bokesch P M. et al, SEDCOM (Safety and Efficacy of Dexmedetomidine Compared With Midazolam) Study Group. Dexmedetomidine vs midazolam for sedation of critically ill patients: a randomized trial. JAMA 2009 301 489-499
    • (2009) JAMA , vol.301 , pp. 489-499
    • Riker, R.R.1    Shehabi, Y.2    Bokesch, P.M.3
  • 49
    • 59849087047 scopus 로고    scopus 로고
    • Dexmedetomidine versus propofol/midazolam for long-term sedation during mechanical ventilation
    • Dexmedetomidine for Continuous Sedation Investigators
    • Ruokonen E, Parviainen I, Jakob S M. et al, Dexmedetomidine for Continuous Sedation Investigators. Dexmedetomidine versus propofol/midazolam for long-term sedation during mechanical ventilation. Intensive Care Med 2009 35 282-290
    • (2009) Intensive Care Med , vol.35 , pp. 282-290
    • Ruokonen, E.1    Parviainen, I.2    Jakob, S.M.3
  • 50
    • 61649123930 scopus 로고    scopus 로고
    • Delirium and sedation in the intensive care unit: Survey of behaviors and attitudes of 1384 healthcare professionals
    • Patel R P., Gambrell M, Speroff T et al. Delirium and sedation in the intensive care unit: survey of behaviors and attitudes of 1384 healthcare professionals. Crit Care Med 2009 37 825-832
    • (2009) Crit Care Med , vol.37 , pp. 825-832
    • Patel, R.P.1    Gambrell, M.2    Speroff, T.3
  • 51
    • 8944221183 scopus 로고    scopus 로고
    • Comparative study of propofol versus midazolam in the sedation of critically ill patients: Results of a prospective, randomized, multicenter trial
    • Chamorro C, de Latorre F J., Montero A et al. Comparative study of propofol versus midazolam in the sedation of critically ill patients: results of a prospective, randomized, multicenter trial. Crit Care Med 1996 24 932-939
    • (1996) Crit Care Med , vol.24 , pp. 932-939
    • Chamorro, C.1    De Latorre, F.J.2    Montero, A.3
  • 52
    • 0030012049 scopus 로고    scopus 로고
    • Sedation of critically ill patients during mechanical ventilation: A comparison of propofol and midazolam
    • Kress J P., O'Connor M F., Pohlman A S. et al. Sedation of critically ill patients during mechanical ventilation: a comparison of propofol and midazolam. Am J Respir Crit Care Med 1996 153 1012-1018
    • (1996) Am J Respir Crit Care Med , vol.153 , pp. 1012-1018
    • Kress, J.P.1    O'Connor, M.F.2    Pohlman, A.S.3
  • 53
    • 0031457178 scopus 로고    scopus 로고
    • Midazolam versus propofol for long-term sedation in the ICU: A randomized prospective comparison
    • Weinbroum A A., Halpern P, Rudick V, Sorkine P, Freedman M, Geller E. Midazolam versus propofol for long-term sedation in the ICU: a randomized prospective comparison. Intensive Care Med 1997 23 1258-1263
    • (1997) Intensive Care Med , vol.23 , pp. 1258-1263
    • Weinbroum, A.A.1    Halpern, P.2    Rudick, V.3    Sorkine, P.4    Freedman, M.5    Geller, E.6
  • 56
    • 0034912516 scopus 로고    scopus 로고
    • Propofol vs midazolam for ICU sedation: A Canadian multicenter randomized trial
    • Study Investigators
    • Hall R I., Sandham D, Cardinal P et al, Study Investigators. Propofol vs midazolam for ICU sedation: a Canadian multicenter randomized trial. Chest 2001 119 1151-1159
    • (2001) Chest , vol.119 , pp. 1151-1159
    • Hall, R.I.1    Sandham, D.2    Cardinal, P.3
  • 57
    • 33646571863 scopus 로고    scopus 로고
    • A randomized trial of intermittent lorazepam versus propofol with daily interruption in mechanically ventilated patients
    • Carson S S., Kress J P., Rodgers J E. et al. A randomized trial of intermittent lorazepam versus propofol with daily interruption in mechanically ventilated patients. Crit Care Med 2006 34 1326-1332
    • (2006) Crit Care Med , vol.34 , pp. 1326-1332
    • Carson, S.S.1    Kress, J.P.2    Rodgers, J.E.3
  • 59
    • 67649450488 scopus 로고    scopus 로고
    • Dexmedetomidine vs. haloperidol in delirious, agitated, intubated patients: A randomised open-label trial
    • Reade M C., O'Sullivan K, Bates S, Goldsmith D, Ainslie W R., Bellomo R. Dexmedetomidine vs. haloperidol in delirious, agitated, intubated patients: a randomised open-label trial. Crit Care 2009 13 R75
    • (2009) Crit Care , vol.13
    • Reade, M.C.1    O'Sullivan, K.2    Bates, S.3    Goldsmith, D.4    Ainslie, W.R.5    Bellomo, R.6
  • 60
    • 0035409423 scopus 로고    scopus 로고
    • Patients' perceptions and responses to procedural pain: Results from Thunder Project II
    • Puntillo K A., White C, Morris A B. et al. Patients' perceptions and responses to procedural pain: results from Thunder Project II. Am J Crit Care 2001 10 238-251
    • (2001) Am J Crit Care , vol.10 , pp. 238-251
    • Puntillo, K.A.1    White, C.2    Morris, A.B.3
  • 61
    • 33646571160 scopus 로고    scopus 로고
    • Sedation during mechanical ventilation: A trial of benzodiazepine and opiate in combination
    • Richman P S., Baram D, Varela M, Glass P S. Sedation during mechanical ventilation: a trial of benzodiazepine and opiate in combination. Crit Care Med 2006 34 1395-1401
    • (2006) Crit Care Med , vol.34 , pp. 1395-1401
    • Richman, P.S.1    Baram, D.2    Varela, M.3    Glass, P.S.4
  • 62
    • 20444363574 scopus 로고    scopus 로고
    • Decreased duration of mechanical ventilation when comparing analgesia-based sedation using remifentanil with standard hypnotic-based sedation for up to 10 days in intensive care unit patients: A randomised trial [ISRCTN47583497]
    • Breen D, Karabinis A, Malbrain M et al. Decreased duration of mechanical ventilation when comparing analgesia-based sedation using remifentanil with standard hypnotic-based sedation for up to 10 days in intensive care unit patients: a randomised trial [ISRCTN47583497]. Crit Care 2005 9 R200-R210
    • (2005) Crit Care , vol.9
    • Breen, D.1    Karabinis, A.2    Malbrain, M.3
  • 63
    • 2342635166 scopus 로고    scopus 로고
    • Remifentanil versus fentanyl for analgesia based sedation to provide patient comfort in the intensive care unit: A randomized, double-blind controlled trial [ISRCTN43755713]
    • Muellejans B, López A, Cross M H., Bonome C, Morrison L, Kirkham A J. Remifentanil versus fentanyl for analgesia based sedation to provide patient comfort in the intensive care unit: a randomized, double-blind controlled trial [ISRCTN43755713]. Crit Care 2004 8 R1-R11
    • (2004) Crit Care , vol.8
    • Muellejans, B.1    López, A.2    Cross, M.H.3    Bonome, C.4    Morrison, L.5    Kirkham, A.J.6
  • 64
    • 34247551128 scopus 로고    scopus 로고
    • Sedation in the intensive care unit with remifentanil/propofol versus midazolam/fentanyl: A randomised, open-label, pharmacoeconomic trial
    • Muellejans B, Matthey T, Scholpp J, Schill M. Sedation in the intensive care unit with remifentanil/propofol versus midazolam/fentanyl: a randomised, open-label, pharmacoeconomic trial. Crit Care 2006 10 R91
    • (2006) Crit Care , vol.10
    • Muellejans, B.1    Matthey, T.2    Scholpp, J.3    Schill, M.4
  • 65
    • 59849105735 scopus 로고    scopus 로고
    • Remifentanil-propofol analgo-sedation shortens duration of ventilation and length of ICU stay compared to a conventional regimen: A centre randomised, cross-over, open-label study in the Netherlands
    • UltiSAFE investigators
    • Rozendaal F W., Spronk P E., Snellen F F. et al, UltiSAFE investigators. Remifentanil-propofol analgo-sedation shortens duration of ventilation and length of ICU stay compared to a conventional regimen: a centre randomised, cross-over, open-label study in the Netherlands. Intensive Care Med 2009 35 291-298
    • (2009) Intensive Care Med , vol.35 , pp. 291-298
    • Rozendaal, F.W.1    Spronk, P.E.2    Snellen, F.F.3
  • 66
    • 65849187703 scopus 로고    scopus 로고
    • Early physical and occupational therapy in mechanically ventilated, critically ill patients: A randomised controlled trial
    • Schweickert W D., Pohlman M C., Pohlman A S. et al. Early physical and occupational therapy in mechanically ventilated, critically ill patients: a randomised controlled trial. Lancet 2009 373 1874-1882
    • (2009) Lancet , vol.373 , pp. 1874-1882
    • Schweickert, W.D.1    Pohlman, M.C.2    Pohlman, A.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.