pH-dependent stability of neuroserpin is mediated by histidines 119 and 138; Implications for the control of β-sheet a and polymerization

Protein Science

Volumn 19, Issue 2, 2010, Pages 220-228

  Belorgey, Didier ^a   Hägglöf, Peter ^a   Onda, Maki ^b   Lomas, David A ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b Osaka Prefecture University   (Japan)

Author keywords

Familial encephalopathy with neuroserpin inclusion bodies; Neuroserpin; Polymerization; Serpins

Indexed keywords

MUTANT PROTEIN; NEUROSERPIN;

ARTICLE; BETA SHEET; CONTROLLED STUDY; PH; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN POLYMERIZATION; PROTEIN STABILITY; WILD TYPE;

HISTIDINE; HYDROGEN-ION CONCENTRATION; MODELS, MOLECULAR; MUTATION; NEUROPEPTIDES; PROTEIN BINDING; PROTEIN STABILITY; PROTEIN STRUCTURE, SECONDARY; SERPINS;

EID: 76749090946     PISSN: 09618368     EISSN: 1469896X     Source Type: Journal    
DOI: 10.1002/pro.299     Document Type: Article

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