Neuroserpin regulates neurite outgrowth in nerve growth factor-treated PC12 cells

Journal of Neurochemistry

Volumn 82, Issue 6, 2002, Pages 1406-1415

  Parmar, Parmjeet K ^a   Coates, Leigh C ^a   Pearson, John F ^b   Hill, Rena M ^a   Birch, Nigel P ^a  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

^b UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

Brain; Plasminogen activators; Protease inhibitors; Serpin

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; EPIDERMAL GROWTH FACTOR; NERVE GROWTH FACTOR; NEUROSERPIN; PLASMINOGEN ACTIVATOR; SERINE PROTEINASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BRAIN; CELL PH; CELL STRAIN; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENZYME INHIBITOR COMPLEX; GENE EXPRESSION; GENE EXPRESSION REGULATION; GROWTH CONE; MEMBRANE VESICLE; NERVE FIBER GROWTH; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; BIOLOGICAL ASSAY; CELL DIFFERENTIATION; EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 2; HYDROGEN-ION CONCENTRATION; MACROMOLECULAR SUBSTANCES; NERVE GROWTH FACTOR; NEURITES; NEURONS; NEUROPEPTIDES; PC12 CELLS; RATS; SECRETORY VESICLES; SERPINS; SUBCELLULAR FRACTIONS; TISSUE PLASMINOGEN ACTIVATOR; TRANSFECTION;

ANIMALIA;

EID: 0036733176     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2002.01100.x     Document Type: Article

References (50)

1. Alexander C. M. and Werb Z. (1989) Proteinases and extracellular matrix remodeling. Current Opinion Cell Biol. 1, 974-982.
2. Baranes D., Lederfein D., Huang Y. Y., Chen M., Bailey C. H. and Kandel E. R. (1998) Tissue plasminogen activator contributes to the late phase of LTP and to synaptic growth in the hippocampal mossy fiber pathway. Neuron 21, 813-825.
3. Berger P., Kozlov S. V., Cinelli P., Kruger S. R., Vogt L. and Sonderegger P. (1999) Neuronal depolarization enhances the transcription of the neuronal serine protease inhibitor neuroserpin. Mol Cellular Neurosciences 14, 455-467.
4. Bonni A. and Greenberg M. E. (1997) Neurotrophin regulation of gene expression. Can J. Neurol, Sci. 24, 272-283.
5. Carbonetto S., Gruver M. M. and Turner D. C. (1983) Nerve fiber growth in culture on fibronectin, collagen, and glycosaminoglycan substrates. J. Neurosci. 3, 2324-2335.
6. Carbonetto S., Harvey W. J., Douville P. J. and Whelan L. (1988) Cellular and molecular models of neuron-matrix adhesion in nerve fiber growth. Prog. Brain Res. 78, 347-352.
7. Chao M. V. (1992) Neurotrophin receptors: a window into neuronal differentiation. Neuron 9, 583-593.
8. Chen Z. L. and Strickland S. (1997) Neuronal death in the hippocampus is promoted by plasmin-catalyzed degradation of laminin. Cell 91, 917-925.
9. Corbit K. C., Foster D. A. and Rosner M. R. (1999) Protein kinase Cdelta mediates neurogenic but not mitogenic activation of mitogen-activated protein kinase in neuronal cells. Mol Cellular Biol. 19, 4209-4218.
10. Corbit K. C., Soh J. W., Yoshida K., Eves E. M., Weinstein I. B. and Rosner M. R. (2000) Different protein kinase C isoforms determine growth factor specificity in neuronal cells. Mol Cellular Biol. 20, 5392-5403.
11. Dear A. E. and Medcalf R. L. (1998) The urokinase-type-plasminogenactivator receptor (CD87) is a pleiotropic molecule. Eur J. Biochem. 252, 185-193.
12. Greene L. A. (1978) Nerve growth factor prevents the death and stimulates the neuronal differentiation of clonal PC12 pheochromocytoma cells in serum-free medium. J. Cell Biol. 78, 747-755.
13. Greene L. A. and Kaplan D. R. (1995) Early events in neurotrophin signalling via Trk and p75 receptors. Current Opinion Neurobiol. 5, 579-587.
14. Greene L. A. and Tischler A. S. (1976) Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc. Natl Acad. Sci. USA 73, 2424-2428.
15. Gualandris A., Jones T. E., Strickland S. and Tsirka S. E. (1996) Membrane depolarization induces calcium-dependent secretion of tissue plasminogen activator. J. Neurosci. 16, 2220-2225.
16. Hastings G. A., Coleman T. A., Haudenschild C. C., Stefansson S., Smith E. R, Barthlow R., Cherry S., Sandkvist M. and Lawrence D. A. (1997) Neuroserpin, a brain-associated inhibitor of tissue plasminogen activator is localized primarily in neurons. Implications for the regulation of motor learning and neuronal survival. J. Biol. Chem. 272, 33062-33067.
17. Hill R. M., Brennan S. O. and Birch N. P. (2001) Expression, purification and functional characterization of the serine protease inhibitor neuroserpin expressed in Drosophila S2 cells. Protein Expression Purification 22, 406-413.
18. Hill R. M., Parmar P. K., Coates L. C., Mezey E., Pearson J. F. and Birch N. P. (2000) Neuroserpin is expressed in the pituitary and adrenal glands and induces the extension of neurite-like processes in AtT-20 cells. Biochem. J. 345, 595-601.
19. Huff K., End D. and Guroff G. (1981) Nerve growth factor-induced alteration in the response of PC12 pheochromocytoma cells to epidermal growth factor. J. Cell Biol. 88, 189-198.
20. Krueger S. R., Ghisu G. P., Cinelli P., Gschwend T. P., Osterwalder T., Wolfer D. P. and Sonderegger P. (1997) Expression of neuroserpin, an inhibitor of tissue plasminogen activator, in the developing and adult nervous system of the mouse. J. Neurosci. 17, 8984-8996.
21. Krystosek A. and Seeds N. W. (1981a) Plasminogen activator secretion by granule neurons in cultures of developing cerebellum. Proc. Natl Acad. Sci. USA 78, 7810-7814.
22. Krystosek A. and Seeds N. W. (1981b) Plasminogen activator release at the neuronal growth cone: Activation of microglia reveals a nonproteolytic cytokine function for tissue plasminogen activator in the central nervous system. Science 213, 1532-1534.
23. Laemmli U.K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685.
24. Loh Y. P., Tam W. W. and Russell J. T. (1984) Measurement of delta pH and membrane potential in secretory vesicles isolated from bovine pituitary intermediate lobe. J. Biol. Chem. 259, 8238-8245.
25. Madani R., Hulo S., Toni N., Madani H., Steimer T., Muller D. and Vassalli J. D. (1999) Enhanced hippocampal long-term potentiation and learning by increased neuronal expression of tissue-type plasminogen activator in transgenic mice. EMBO J. 18, 3007-3012.
26. Monard D. (1988) Cell-derived proteases and protease inhibitors as regulators of neurite outgrowth. Trends Neurosciences 11, 541-544.
27. Moonen G., Grau-Wagemans M. P. and Selak I. (1982) Plasminogen activator-plasmin system and neuronal migration: neuronal migration is retarded in mice lacking the tissue plasminogen activator gene. Nature 298, 753-755.
28. Neufeld G., Gospodarowicz D., Dodge L. and Fujii D. K. (1987) Heparin modulation of the neurotropic effects of acidic and basic fibroblast growth factors and nerve growth factor on PC12 cells. J. Cell. Physiol. 131, 131-140.
29. Osterwalder T., Cinelli P., Baici A., Pennella A., Krueger S. R., Schrimpf S. P., Meins M. and Sonderegger P. (1998) The axonally secreted serine proteinase inhibitor, neuroserpin, inhibits plasminogen activators and plasmin but not thrombin. J. Biol. Chem. 273, 2312-2321.
30. Osterwalder T., Contartese J., Stoeckli E. T., Kuhn T. B. and Sonderegger P. (1996) Neuroserpin, an axonally secreted serine protease inhibitor. EMBO J. 15, 2944-2953.
31. Parmer R. J., Mahata M., Mahata S., Sebald M. T., O'Connor D. T. and Miles L. A. (1997) Tissue plasminogen activator (t-PA) is targeted to the regulated secretory pathway. Catecholamine storage vesicles as a reservoir for the rapid release of t-PA. J. Biol. Chem. 272, 1976-1982.
32. Pennica D., Holmes W. E., Kohr W. J., Harkins R. N., Vehar G. A., Ward C. A., Bennett W. F., Yelverton E., Seeburg P. H., Heyneker H. L., Goeddel D. V. and Collen D. (1983) Cloning and expression of human tissue-type plasminogen activator cDNA in E. coli. Nature 301, 214-221.
33. Pittman R. N. and DiBenedetto A. J. (1995) PC12 cells overexpressing tissue plasminogen activator regenerate neurites to a greater extent and migrate faster than control cells in complex extracellular matrix. J. Neurochem. 64, 566-575.
34. Pittman R. N., Ivins J. K. and Buettner H. M. (1989) Neuronal plasminogen activators: cell surface binding sites and involvement in neurite outgrowth. J. Neurosci. 9, 4269-4286.
35. Pollock J. D., Krempin M. and Rudy B. (1990) Differential effects of NGF, FGF, EGF, cAMP, and dexamethasone on neurite outgrowth and sodium channel expression in PC12 cells. J. Neurosci. 10, 2626-2637.
36. Qian Z., Gilbert M. E., Colicos M. A., Kandel E. R. and Kuhl D. (1993) Tissue-plasminogen activator is induced as an immediate-early gene during seizure, kindling and long-term potentiation. Nature 361, 453-457.
37. Romanic A. M. and Madri J. A. (1994) Extracellular matrix-degrading proteinases in the nervous system. Brain Pathol 4, 145-156.
38. Rudkin B. B., Lazarovici P., Levi B. Z., Abe Y., Fujita K. and Guroff G. (1989) Cell cycle-specific action of nerve growth factor in PC12 cells: differentiation without proliferation. EMBO J. 8, 3319-3325.
39. Seeds N. W., Verrall S., Friedman G., Hayden S., Gadotti D., Haffke S., Christensen K., Gardner B., McGuire P. and Krystosek A. (1992) Plasminogen activators and plasminogen activator inhibitors in neural development. Ann. New York Acad. Sciences 667, 32-40.
40. Seeds N. W., Verrall S., McGuire P. and Friedmann G. (1990) Plasminogen activator in the developing nervous system. In: Serine Proteases and Their Serpin Inhibitors in the Nervous System (Festoff B. W., ed.), pp. 173-184. Plenum Press, New York.
41. Seeds N. W., Williams B. L. and Bickford P. C. (1995) Tissue plasminogen activator induction in Purkinje neurons after cerebellar motor learning. Science 270, 1992-1994.
42. Shiosaka S. and Yoshida S. (2000) Synaptic microenvironments structural plasticity, adhesion molecules, proteases and their inhibitors. Neuroscience Res. 37, 85-89.
43. Siconolfi L. and Seeds N. (2001a) Mice lacking tPA, uPA, or plasminogen genes showed delayed functional recovery after sciatic nerve crush. J. Neurosci. 21, 4348-4355.
44. Siconolfi L. B. and Seeds N. W. (2001b) Induction of the plasminogen activator system accompanies peripheral nerve regeneration after sciatic nerve crush. J. Neurosci. 21, 4336-4347.
45. Stefansson S., Haudenschild C. A. and Lawrence D. A. (1998) The role of plasminogen activator inhibitor-1 and vitronectin in vascular wound healing. Trends Cardiovascular Med. 8, 175-180.
46. Stefansson S. and Lawrence D. A. (1996) The serpin PAI-1 inhibits cell migration by blocking integrin alpha V beta 3 binding to vitronectin [see comments]. Nature 383, 441-443.
47. Stoeckli E. T., Lemkin P. F., Kuhn T. B., Ruegg M. A., Heller M. and Sonderegger P. (1989) Identification of proteins secreted from axons of embryonic dorsal-root-ganglia neurons. Eur. J. Biochem. 180, 249-258.
48. Sumi Y., Dent M. A., Owen D. E., Seeley P. J. and Morris R. J. (1992) The expression of tissue and urokinase-type plasminogen activators in neural development suggests different modes of proteolytic involvement in neuronal growth. Development 116, 625-637.
49. Turgeon V. L. and Houenou L. J. (1997) The role of thrombin-like (serine) proteases in the development, plasticity and pathology of the nervous system. Brain Res. - Brain Res. Rev. 25, 85-95.
50. Wu Y. P., Siao C. J., Lu W., Sung T. C., Frohman M. A., Milev P., Bugge T. H., Degen J. L., Levine J. M., Margolis R. U. and Tsirka S. E. (2000) The tissue plasminogen activator (tPA)/plasmin extracellular proteolytic system regulates seizure-induced hippocampal mossy fiber outgrowth through a proteoglycan substrate. J. Cell Biol. 148, 1295-1304.